Deva Vegan Omega-3 DHA Supplement

Omega-3s may reduce headaches

Based on 9 Researches

Long-chain omega-3 fatty acids and headache in the U.S. population.

Most Relevant Research

We aimed to explore the link between dietary intake of long-chain omega-3 fatty acids, specifically docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and their potential impact on headache prevalence in the U.S. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we looked at a diverse group of over 12,000 adults aged 20 and older.

Through interviews, participants reported experiences of severe headaches or migraines in the past three months. We also measured dietary EPA and DHA from their food intake and assessed levels of C-reactive protein, which is an indicator of inflammation. Our analysis suggested that increased intake of omega-3 fatty acids correlated with a lower prevalence of severe headaches or migraines. Specifically, each log unit increase in EPA was linked to a 6% reduction in the prevalence—while DHA showed a similar reduction.

Interestingly, we found that this effect was more pronounced among non-Mexican Hispanic participants compared to others. Importantly, our results remained robust even after considering inflammation levels. Thus, this study supports the idea that omega-3 fatty acids may be beneficial in helping to prevent or alleviate headaches.

9.5

Headache relief

Most Useful Review

I used to prefer animal omega, but it didn't suit me. This omega combined with 5-htp interestingly alleviated my headache. The price-quality ratio is satisfactory.

Reflux

Excellent! This plant-based omega 3 doesn't taste of fish, and I feel better using it as fish omega caused me reflux.

Allergies

Docosahexaenoic acid's anti-inflammatory effects

Based on 12 Researches

Resolvin D2 regulates type 2 inflammatory responses and promotes resolution of mouse allergic inflammation.

Most Relevant Research

We examined how docosahexaenoic acid, particularly its metabolite resolvin D2, influences allergic reactions and inflammation. Our focus was on type 2 inflammatory responses, often seen in allergic conditions. Through rigorous methodologies, including control groups, the study assessed how resolvin D2 can help in regulating these responses and promote the resolution of allergy-related inflammation in mice.

Our findings revealed that resolvin D2 plays a significant role in effectively managing allergic inflammation. It helps to mitigate the intense reactions typically associated with allergies, providing a clearer path toward alleviating symptoms.

This research demonstrates the potential of docosahexaenoic acid in offering therapeutic benefits for those suffering from type 2 inflammation due to allergies, and suggests that targeted treatments could improve overall allergen management.

9.5

Immediate moisturising effect

Most Useful Review

The ingredients are excellent and suitable for my fish allergies. The quality is fantastic as I noticed an immediate moisturising effect on my skin from the second day. I also appreciate that there is no aftertaste; it is sweet and easy to swallow.

Autoimmune Disorder

DHA shows promise for autoimmunity

Neuroprotective and antioxidant effects of docosahexaenoic acid (DHA) in an experimental model of multiple sclerosis.

Most Relevant Research

We conducted a study to evaluate how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, can impact autoimmune disorders, specifically using an animal model of multiple sclerosis (MS). In this investigation, we worked with twenty-five Dark Agouti rats, dividing them into distinct groups. Some received DHA, while others served as controls, allowing for comparisons of its effectiveness on clinical symptoms and levels of oxidative stress.

Over the course of 51 days, DHA was administered via injections, with a daily 40 mg/kg dosage given five days a week. What we observed was quite encouraging. The DHA supplementation appeared to lead to a reduction in oxidative stress markers and showed improvements in clinical scores related to the disease. These results suggest that DHA has the potential to positively influence the progression of MS.

Furthermore, we believe this effect may be linked to DHA’s ability to activate Nrf2, an important antioxidant factor in our bodies. Overall, our findings indicate that DHA could be a beneficial treatment option for managing multiple sclerosis and possibly other autoimmune conditions.

9.5

Fish craving ceased

Most Useful Review

Effective! I discovered this version of omega from Sasha Avocado @avocadosasha. During my third month of pregnancy, I craved fish despite not eating it for 2-2.5 years. I didn’t take a test for this deficiency. After a month of taking it, my urge for fish vanished. This shows its effectiveness as my diet did not change. I consumed two cans.

Chronic Fatigue Syndrome

Essential fatty acids aid fatigue syndrome

Based on 2 Researches

Effect of high doses of essential fatty acids on the postviral fatigue syndrome.

Most Relevant Research

We conducted a study to evaluate the effectiveness of essential fatty acids, particularly docosahexaenoic acid (DHA), in treating postviral fatigue syndrome, which affects many individuals after a viral infection.

In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.

Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.

Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.

9.5

Increased energy

Most Useful Review

I was initially hesitant about this substitute for another vegetarian Omega-3. However, this product has been perfect and has no unpleasant aftertaste. Since taking Omega-3, I feel far more energetic, shaking off the stress and fatigue that had plagued me, including symptoms of chronic fatigue syndrome. I'm committed to ordering this from Korea. Thank you, iHerb!

Depression

DHA shows potential for depression

Based on 15 Researches

The Efficacy of Omega-3 Fatty Acids as the Monotherapy for Depression: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.

Most Relevant Research

We conducted a study to find out whether docosahexaenoic acid (DHA), a type of omega-3 fatty acid, could effectively help those dealing with major depressive disorder (MDD). Over the course of 12 weeks, 60 participants were involved in a double-blind, placebo-controlled trial. They were divided into two groups: one received 3.2 grams of DHA daily, while the other group was given an equivalent amount of soybean oil as a placebo.

Throughout the study, we measured depression levels using the Hamilton Rating Scale for Depression (HRSD). Our results were intriguing—those taking the DHA showed significant improvements in their depression scores compared to the placebo group by weeks 4, 6, 8, and 12. While we noted that 26.7% of participants receiving DHA achieved remission by week 12, this was not statistically significant in comparison to the placebo group.

Overall, our findings support the idea that DHA may serve as a promising alternative treatment for individuals suffering from MDD. Although the results are encouraging, we recognize the need for further research to confirm these benefits conclusively.

9.5

Alleviates depression

Most Useful Review

I began taking this vegan DHA during my pregnancy, and I’ve continued as it significantly alleviates my depression. I've tried other brands, but none have worked as effectively as Deva.

Fibromyalgia

Improved mental clarity

Most Useful Review

Fabulous product! I have fibromyalgia and have experienced 'fibro-fog'. Within two days of taking this supplement, I felt mental clarity and significant improvement in my short-term memory. This is an excellent product.

Heart Attack

DHA aids post-heart attack recovery

The polyunsaturated fatty acids, EPA and DHA, ameliorate myocardial infarction-induced heart failure by inhibiting p300-HAT activity in rats.

Most Relevant Research

We explored the effects of docosahexaenoic acid (DHA) on heart attack recovery in rats. The study aimed to understand how DHA, alongside eicosapentaenoic acid (EPA), can influence heart failure following myocardial infarction (MI).

Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.

Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.

Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.

8.8

Heart health improvement

Most Useful Review

My dad has taken this excellent supplement for years, and it aids in maintaining his heart's healthy function. A great source of omega.

Heart Disease

Omega-3s may reduce coronary risk

A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.

Most Relevant Research

We explored the impact of omega-3 fatty acids, particularly docosahexaenoic acid (DHA), on heart disease via the large-scale VITAL study. This trial involved over 25,000 older adults in the U.S. who were monitored for about 5.3 years to assess how omega-3 FA supplementation influences cardiovascular events.

Although the findings from the VITAL trial indicated no significant results for major cardiovascular events, our analysis employing Bayesian methods suggested a different story. By incorporating previous research evidence, we found that daily supplementation of omega-3 fatty acids appears to significantly lower the risk of coronary events like heart attacks. However, it's important to note that this effect did not extend to reducing the risk of stroke.

Overall, this reevaluation supports the idea that omega-3 fatty acids, including DHA, could play a meaningful role in heart health, especially for preventing coronary-related issues. While the trial didn't show an impact on all aspects of heart disease, the results regarding coronary events provide valuable insights for the use of omega-3s in primary prevention strategies.

8.8

Improves heart health

Most Useful Review

I have not consumed meat, fish, or seafood since 2008, making Omega-3 and vitamin B-12 essential staples from iHerb. Omega-3 offers several benefits: it enhances metabolism, supports heart health by lowering blood pressure and cholesterol, and improves joint function. It positively affects the brain and memory, boosts immunity, and elevates mood. Insufficient Omega-3 can lead to skin issues, fatigue, and even heart disease. Including Omega-3-rich foods in my diet or opting for this product ensures I remain healthy. Wishing everyone health and love! 💗

High Cholesterol

DHA lowers cholesterol; boosts metabolism

Based on 13 Researches

F-Fluorodeoxyglucose positron emission tomography/computed tomography imaging reveals the protective effect of docosahexaenoic acid on glucose metabolism by reducing brain 27-hydroxycholesterol.

Most Relevant Research

We aimed to investigate how docosahexaenoic acid (DHA) impacts cholesterol levels and brain glucose metabolism. In our study, we focused on aged SAMP8 mice, dividing them into two groups: a control group and one receiving DHA supplementation.

Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.

These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.

9.5

High-quality ingredients

Most Useful Review

The ingredients are of high quality and suitable for adults. Without fish oil and with a pleasant taste, the package lasts for three months. I've seen excellent results in my blood tests, with improved HDL cholesterol and reduced LDL cholesterol levels. I was just about to reorder, but unfortunately, it’s not available at the moment.

Knee Pain

Fish oil improves knee function

Based on 9 Researches

Efficacy and Safety of Fish Oil in Treatment of Knee Osteoarthritis.

Most Relevant Research

We explored how fish oil, rich in docosahexaenoic acid (DHA), can impact knee pain, particularly for those suffering from osteoarthritis. In our study, we involved 75 participants, divided into three groups, each taking either 1,000 mg or 2,000 mg of fish oil daily for eight weeks. We carefully measured their knee pain and walking abilities before and after the supplementation.

The results were encouraging. Those who took fish oil reported notable improvements in knee performance and function compared to a control group. On a satisfaction scale, the average score was an impressive 9.06 out of 10! While most participants experienced the benefits of fish oil without complications, there was one case of hematuria that was unrelated to the treatment.

Overall, our findings suggest that taking 1,000 to 2,000 mg of fish oil daily can significantly enhance knee performance and is safe for individuals with mild to moderate knee osteoarthritis. However, it’s worth noting that increasing the dose beyond 1,000 mg didn't yield greater benefits.

9.5

Vegan supplement benefits

Most Useful Review

This supplement is fantastic for my knee pain. I need to take a DHA/EPA supplement regularly to avoid the pain, and I appreciate that this one is vegan sourced with quality ingredients.

Arthritis

DHA benefits osteoarthritis treatment

Based on 14 Researches

DHA attenuates cartilage degeneration by mediating apoptosis and autophagy in human chondrocytes and rat models of osteoarthritis.

Most Relevant Research

We set out to investigate how docosahexaenoic acid (DHA), a fatty acid known for its health benefits, can affect osteoarthritis (OA), a common degenerative joint disease, particularly among older adults. Using both human chondrocyte models stimulated by IL-1β and rat models created through surgical methods, we aimed to understand DHA's potential to impact chondrocyte behavior and cartilage health.

Our observations revealed that DHA significantly promotes the growth of chondrocytes while reducing cell death, which is a key concern in OA. Notably, we found an increase in autophagosomes—structures that help break down cellular waste—within cells treated with DHA, suggesting enhanced cell health.

In comparing groups, those treated with DHA exhibited healthier cartilage characterized by thickened tissue and a decrease in degeneration when compared to the untreated OA group. We also noted an increase in collagen production, vital for maintaining joint structure. The biochemical analysis indicated that DHA potentially exerts its effects by inhibiting certain pathways associated with cell growth and stress responses, thus enhancing chondrocyte proliferation and survival.

Overall, our findings contribute valuable insights into how DHA can be leveraged as a therapeutic approach for OA, emphasizing its role in protecting and restoring cartilage health.

8.8

Reduced arthritis symptoms

Most Useful Review

DEVA vegan omega 3 is an excellent product. As a sceptic not easily influenced by placebo effects, I find it has alleviated some arthritis symptoms in my fingers and knees, which is pleasing. The price is fantastic, and I’m also impressed with iHerb's service.

Prenatal docosahexaenoic acid supplementation and infant morbidity: randomized controlled trial.

Most Relevant Research

We conducted a double-blind randomized controlled trial to understand how prenatal supplementation of docosahexaenoic acid (DHA) might influence infant health, particularly concerning the common cold. Pregnant women were given either a daily dose of 400 mg of DHA or a placebo starting at 18 to 22 weeks of gestation until childbirth.

Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.

While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.

Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.

This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.

8.8

Helps with cold

Most Useful Review

I take it before the onset of the common cold, as it helps me adapt to colder weather and prevents me from feeling too cold. It also assists with high cholesterol. I chose this vegan formula based on my doctor's recommendation, as it is deemed more beneficial and easily absorbed.

Dizziness

Gout

DHA's potential in gout inflammation

Based on 3 Researches

DHA protects against monosodium urate-induced inflammation through modulation of oxidative stress.

Most Relevant Research

We explored how docosahexaenoic acid (DHA) might help manage inflammation related to gout, specifically by examining its effects on monosodium urate (MSU) phagocytized by immune cells. Our study revealed that DHA significantly reduced the production and release of key inflammatory markers like interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in cell experiments.

We also observed that DHA helps lessen the production of harmful reactive oxygen species (ROS) that can contribute to inflammation. Notably, DHA aided the movement of a critical protein, nuclear factor E2-related factor 2 (Nrf2), into the cell nucleus, which then promoted the expression of several protective antioxidant enzymes. This is important because these enzymes play a vital role in maintaining cellular balance and mitigating oxidative stress.

Additionally, DHA improved mitochondrial function that was impaired by MSU, highlighting its protective effects. In real-world settings, when we administered DHA-rich microalgal oil to laboratory mice, we noted a decrease in the number of neutrophils, or inflammation-prone white blood cells, alongside lowered inflammatory responses.

Overall, our findings suggest that DHA or its rich sources like microalgal oil could be a valuable natural option for preventing inflammation linked to gout by tackling oxidative stress effectively.

8.8

Gout relief noted

Most Useful Review

Vegan Omega 3 is new to me, but I have experienced no adverse effects. The inflammation from gout has decreased, and I hope this product will resolve the issue.

Heartburn

Effective alternative

Most Useful Review

Finally, a good vegan omega! I sought a high-quality omega with the right ingredients and found this one that I wouldn't change. Fish oil gives me headaches and heartburn, but this serves as a fantastic alternative. The only downside is that it tends to sell out quickly.

Liver Disease

DHA-PS promotes liver recovery

DHA-enriched phosphatidylserine ameliorates cyclophosphamide-induced liver injury via regulating the gut-liver axis.

Most Relevant Research

We investigated the potential of DHA-enriched phosphatidylserine (DHA-PS) in addressing liver injuries caused by cyclophosphamide in mice. By administering cyclophosphamide over five days, we created a model to simulate this liver damage. Following this, we treated the mice with different doses of DHA-PS for a week to see if it could help heal their livers.

Our findings were quite promising. The mice receiving DHA-PS experienced significant improvements in key liver health indicators, including reduced inflammation and oxidative stress. Through advanced analysis, we discovered that DHA-PS helped correct metabolic imbalances caused by cyclophosphamide, which is a crucial aspect of liver recovery.

Additionally, we observed that DHA-PS has a positive impact on the gut-liver axis. This treatment restored the intestinal barrier, reduced harmful compounds in the bloodstream, and improved overall gut microbiota health. By balancing the gut bacteria, we enhanced the overall health of the mice.

Overall, the results suggest that DHA-PS could be a valuable therapeutic option or functional food for combating liver injuries related to cyclophosphamide. This study highlights the potential benefits of DHA on liver health and underscores the importance of the gut-liver connection.

Omega 3 supplement

Most Useful Review

This omega supplement is recommended by a practising doctor to help replenish omega 3 for those with deficiencies, as well as for pregnant and lactating women and those with liver disease. The herbal composition is excellent!

Back Pain

Omega-3s reduce disc degeneration

Based on 4 Researches

Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration.

Most Relevant Research

We aimed to find out how docosahexaenoic acid (DHA), a key omega-3 fatty acid, could affect intervertebral disc (IVD) degeneration, a common cause of lower back pain. In our study, we used a group of 12 rats, all of whom underwent a procedure to induce disc degeneration.

After the injury, half of the rats were given a daily supplement of omega-3 fatty acids, while the other half received only a sugar solution as control. Over the course of the study, we measured various outcomes related to inflammation and disc health.

We observed that the omega-3 group showed a significant reduction in blood markers associated with inflammation. Additionally, the results indicated that those receiving DHA were less affected by disc dehydration, and the tissue damage due to the induced injury was noticeably less severe in this group.

Overall, this suggests that increasing our intake of omega-3 fatty acids, like DHA, may offer protective effects against the degeneration of intervertebral discs and could potentially ease back pain related to this condition.

7.5

Relieves back pain

Most Useful Review

This product appears to be making a difference in managing my arthritis and back pain. It has also improved my skin.

Bruise

Excellent! I get bruises from formulas containing EPA, but not this one. It appears to uplift my mood slightly when I remember to take it. I prefer this over the dropper version, which tastes dreadful.

Blood Clot

DHA may reduce blood clots

Based on 10 Researches

Potential Benefits of Omega-3 Polyunsaturated Fatty Acids (N3PUFAs) on Cardiovascular Health Associated with COVID-19: An Update for 2023.

Most Relevant Research

We delved into the benefits of docosahexaenoic acid (DHA) in relation to blood clotting, especially in the context of cardiovascular health and COVID-19. DHA, a form of omega-3 fatty acid, shows promise in influencing how our body's clotting mechanism works. By integrating into cell membranes, DHA helps reduce inflammation and support overall epithelial function.

Studies indicate a positive link between increased DHA intake and lower risks of thrombotic outcomes, suggesting that it may be beneficial for those at risk of blood clots. The research highlights that both DHA and its counterpart, eicosapentaenoic acid (EPA), play a role in creating bioactive compounds that support cardiovascular health.

Given its safety profile, DHA emerges as a potential adjunctive treatment for individuals vulnerable to cardiovascular issues due to COVID-19. We also consider the optimal forms and dosages for maximum effectiveness, showing how accessible nutrition can aid in maintaining better heart health.

6.3

Stable blood coagulation

Most Useful Review

My mother's blood coagulation function is somewhat poor, and her skin is prone to allergies. I discovered that the EPA component can lead to increased bleeding, hence pregnant women often use algae oil. I decided to try this cost-effective product, and I feel that her blood coagulation function has become much more stable.

Eczema

DHA shows promise for eczema

Questionable

Based on 7 Researches

Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial.

Most Relevant Research

In a controlled trial, we assessed how docosahexaenoic acid (DHA)—an omega-3 fatty acid—affects atopic eczema. Fifty-three patients, aged 18 to 40, were randomly assigned to receive either 5.4 grams of DHA daily or an isoenergetic control comprising saturated fatty acids for eight weeks. This double-blind setup helped ensure that neither the participants nor the researchers knew who received which treatment, thereby reducing bias in the results.

Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.

Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.

4.8

Minimal effects noted

Most Useful Review

I began using this to help with my acne and eczema, but I have not yet seen a significant difference. The great thing is that there is no fishy aftertaste.

Leg Cramps

Daily consumption needed

Most Useful Review

I always eat it. I believe I tried it a few years ago because it was a vegetable, yet there were no cicadas. If I do not consume Egg Arthur for about a week, the leg cramps return, necessitating daily intake.

Nausea