'
SCIENTIFIC SCORE
Most Likely Effective
Based on 9 Researches
7.4
USERS' SCORE
Excellent
Based on 5 Reviews
9.3
Supplement Facts
Serving Size:  1 vegan softgel
Amount Per Serving
%DV
Calories
5
_
Total Fat
0.5 g
<1%‡
Microalgae Oil (40% DHA)which typically provides:
500 mg
*
DHA (Docosahexaenoic Acid) [Ω-3]
200 mg
*

Top Medical Research Studies

8
Omega-3s may reduce headaches
Long-chain omega-3 fatty acids and headache in the U.S. population.
Strong relevance to study findings
We aimed to explore the link between dietary intake of long-chain omega-3 fatty acids, specifically docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and their potential impact on headache prevalence in the U.S. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we looked at a diverse group of over 12,000 adults aged 20 and older.

Through interviews, participants reported experiences of severe headaches or migraines in the past three months. We also measured dietary EPA and DHA from their food intake and assessed levels of C-reactive protein, which is an indicator of inflammation. Our analysis suggested that increased intake of omega-3 fatty acids correlated with a lower prevalence of severe headaches or migraines. Specifically, each log unit increase in EPA was linked to a 6% reduction in the prevalence—while DHA showed a similar reduction.

Interestingly, we found that this effect was more pronounced among non-Mexican Hispanic participants compared to others. Importantly, our results remained robust even after considering inflammation levels. Thus, this study supports the idea that omega-3 fatty acids may be beneficial in helping to prevent or alleviate headaches.
Read More
9
Omega-3 diet reduces headache pain
Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress.
Study shows positive dietary impact
We explored how dietary changes, specifically increasing omega-3 fatty acids like docosahexaenoic acid (DHA) while lowering omega-6 fatty acids, can influence headache pain. In a trial involving 55 chronic headache patients, we observed significant benefits from this targeted dietary intervention.

Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.

The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Read More
7
DHA reduces migraine frequency
The relationship between different fatty acids intake and frequency of migraine attacks.
Highly relevant to headache treatment
In our exploration of how different fatty acids influence migraine frequency, we found intriguing results regarding docosahexaenoic acid (DHA). We assessed the dietary habits of 105 migraine patients aged between 15 and 50 years, using a food frequency questionnaire to track their intake of various fatty acids such as eicosapentaenoic acid (EPA) and saturated fatty acids (SFA).

The data told a compelling story: a higher intake of omega-3 fatty acids, specifically DHA and EPA, was linked to a lower frequency of migraine attacks. When we looked closer, we discovered that for individuals with lower levels of these omega-3 fats, the frequency of migraines was notably higher. This trend was consistent across both men and women, suggesting a robust relationship between increased DHA intake and reduced headache occurrences.

On the other hand, the study did not find any significant connection between saturated fatty acid intake and migraine frequency. This could indicate that not all fats are created equal when it comes to managing headaches. The findings point to the potential of DHA, alongside EPA, as a dietary intervention for migraine relief, although further studies are needed to deepen our understanding.
Read More

Most Useful Reviews

9.5
Headache relief
I used to prefer animal omega, but it didn't suit me. This omega combined with 5-htp interestingly alleviated my headache. The price-quality ratio is satisfactory.
Read More
9.5
Headache improvement
The quality is excellent. This vegetarian omega-3 is better than fish oil for me. It has helped alleviate my headaches, and the taste is acceptable.
Read More
9.5
Great alternative
Finally, I've found a good vegan omega! Unlike fish oil, which causes headaches and heartburn, this product is a fantastic alternative. The only downside is it goes out of stock quickly.
Read More

Medical Researches

SCIENTIFIC SCORE
Most Likely Effective
Based on 9 Researches
7.4
9.5
Omega-3s effectively reduce headaches
Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.
Dietary intervention impacts headaches
We conducted a clinical trial to see how dietary changes targeting omega-3 and omega-6 fatty acids could help people dealing with chronic headaches. Over 12 weeks, we divided participants into two groups: one that increased their omega-3 intake while reducing omega-6 and another that just focused on lowering omega-6.

Our findings were quite promising! Those in the group increasing their omega-3 levels experienced a greater reduction in headache severity and frequency compared to those simply lowering omega-6. Specifically, the high omega-3 group had a significant drop in both daily headache hours and pain impact, while altering levels of important headache-relief mediators in the body.

This suggests that increasing omega-3, particularly docosahexaenoic acid, can be an effective strategy for reducing headache symptoms and improving overall quality of life among chronic headache sufferers. These dietary adjustments could provide a new avenue for managing headaches more effectively.
Read More
9
Omega-3 diet reduces headache pain
Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress.
Study shows positive dietary impact
We explored how dietary changes, specifically increasing omega-3 fatty acids like docosahexaenoic acid (DHA) while lowering omega-6 fatty acids, can influence headache pain. In a trial involving 55 chronic headache patients, we observed significant benefits from this targeted dietary intervention.

Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.

The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Read More
8
DHA may predict headache severity
Identifying oxidized lipid mediators as prognostic biomarkers of chronic posttraumatic headache.
Moderate relevance to the study
We investigated the potential of docosahexaenoic acid (DHA) and its oxidized derivatives in predicting chronic posttraumatic headache (PTH) after traumatic brain injury (TBI). In a study involving patients within three days of a TBI, we focused on measuring circulating oxylipins—molecules derived from fatty acids like DHA and arachidonic acid. Our goal was to see if these could help indicate which patients might develop chronic headaches later on.

We found that some DHA-related oxylipins, specifically 4-hydroxy-DHA and 19,20-epoxy-docosapentaenoate, seemed to correlate with lower headache severity. Conversely, a linoleic acid derivative known as 11-hydroxy-9-epoxy-octadecenoate was positively linked to more severe headaches. This suggests that not all fatty acid derivatives act similarly concerning headache severity.

Our findings support the idea that DHA-derived oxylipins have the potential to serve as biomarkers for predicting the onset of chronic headaches after a brain injury, highlighting an exciting area for further research into treatment options.
Read More
8
Omega-3s may reduce headaches
Long-chain omega-3 fatty acids and headache in the U.S. population.
Strong relevance to study findings
We aimed to explore the link between dietary intake of long-chain omega-3 fatty acids, specifically docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and their potential impact on headache prevalence in the U.S. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we looked at a diverse group of over 12,000 adults aged 20 and older.

Through interviews, participants reported experiences of severe headaches or migraines in the past three months. We also measured dietary EPA and DHA from their food intake and assessed levels of C-reactive protein, which is an indicator of inflammation. Our analysis suggested that increased intake of omega-3 fatty acids correlated with a lower prevalence of severe headaches or migraines. Specifically, each log unit increase in EPA was linked to a 6% reduction in the prevalence—while DHA showed a similar reduction.

Interestingly, we found that this effect was more pronounced among non-Mexican Hispanic participants compared to others. Importantly, our results remained robust even after considering inflammation levels. Thus, this study supports the idea that omega-3 fatty acids may be beneficial in helping to prevent or alleviate headaches.
Read More
7
Study on omega-3 and headaches
Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions.
Explores n-6/n-3 PUFA impact
We examined how the balance of omega-6 and omega-3 polyunsaturated fatty acids (PUFAs) influences headache intensity. The study included 605 adults and focused on various chronic pain conditions, including orofacial pain, headache, low back pain, irritable bowel syndrome, and bodily pain.

The findings revealed that a higher ratio of omega-6 to omega-3 fatty acids was linked to increased pain intensity across several conditions, particularly in headaches. Interestingly, docosahexaenoic acid (DHA), a specific type of omega-3 fatty acid, was found to have a strong inverse relationship with pain intensity, indicating that higher levels of DHA may help reduce headache severity.

However, it’s important to note that while the study found a consistent association between the overall ratio of omega-6 to omega-3 and headache intensity, it did not isolate the effect of DHA alone on headaches. This suggests that while DHA may be beneficial, its exact impact on headache pain requires further investigation to fully understand its role.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 5 Reviews
9.3
9.5
Headache relief
I used to prefer animal omega, but it didn't suit me. This omega combined with 5-htp interestingly alleviated my headache. The price-quality ratio is satisfactory.
9.5
Headache improvement
The quality is excellent. This vegetarian omega-3 is better than fish oil for me. It has helped alleviate my headaches, and the taste is acceptable.
9.5
Great alternative
Finally, I've found a good vegan omega! Unlike fish oil, which causes headaches and heartburn, this product is a fantastic alternative. The only downside is it goes out of stock quickly.
9.5
Effective against headaches
This distinctive product is suitable for vegetarians, with an acceptable taste and price. After using this omega, my wife's headaches disappeared, so I will order more in the future.
8.8
Headaches reduced
Wonderful. Although I am not vegan, I like this omega oil. It does not give me a headache like other omegas and the softgels are a manageable size for the kids.
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