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SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 vegan softgel
Amount Per Serving
%DV
Calories
5
_
Total Fat
0.5 g
<1%‡
Microalgae Oil (40% DHA)which typically provides:
500 mg
*
DHA (Docosahexaenoic Acid) [Ω-3]
200 mg
*
Top Medical Research Studies
9
DHA aids post-heart attack recovery
The polyunsaturated fatty acids, EPA and DHA, ameliorate myocardial infarction-induced heart failure by inhibiting p300-HAT activity in rats.
Relevant to myocardial infarction treatments
We explored the effects of docosahexaenoic acid (DHA) on heart attack recovery in rats. The study aimed to understand how DHA, alongside eicosapentaenoic acid (EPA), can influence heart failure following myocardial infarction (MI).
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Read More
9
DHA supports heart recovery post-MI
Metabolic transformation of fat in obesity determines the inflammation resolving capacity of splenocardiac and cardiorenal networks in heart failure.
Study shows DHA's positive role
We investigated how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, influences recovery following a heart attack (MI) in the context of dietary fat intake. The study began by feeding mice with safflower oil (rich in omega-6 fatty acids) for 12 weeks, followed by DHA supplementation for another 8 weeks before inducing a heart attack.
Through this process, we observed that the early intake of safflower oil led to heightened inflammation, delaying the body’s ability to heal. However, when we supplemented with DHA, we noted a favorable shift. DHA increased the levels of specialized proresolving mediators (SPMs) that help the body resolve inflammation. These mediators seemed to counteract the negative effects of safflower oil by enhancing mechanisms in both the heart and kidneys critical for recovery post-MI.
Additionally, DHA contributed to an increase in resolving macrophages, which play a vital role in repairing the heart, and it also elevated T regulatory cells in the heart tissue during chronic heart failure. This might suggest that transitioning from a diet high in omega-6 fatty acids to one rich in omega-3s like DHA could improve outcomes after heart attacks.
Overall, while excessive safflower oil intake worsens inflammation and affects heart recovery, DHA promotes a healthier resolving phase, supporting better heart and kidney function in the aftermath of a heart attack.
Through this process, we observed that the early intake of safflower oil led to heightened inflammation, delaying the body’s ability to heal. However, when we supplemented with DHA, we noted a favorable shift. DHA increased the levels of specialized proresolving mediators (SPMs) that help the body resolve inflammation. These mediators seemed to counteract the negative effects of safflower oil by enhancing mechanisms in both the heart and kidneys critical for recovery post-MI.
Additionally, DHA contributed to an increase in resolving macrophages, which play a vital role in repairing the heart, and it also elevated T regulatory cells in the heart tissue during chronic heart failure. This might suggest that transitioning from a diet high in omega-6 fatty acids to one rich in omega-3s like DHA could improve outcomes after heart attacks.
Overall, while excessive safflower oil intake worsens inflammation and affects heart recovery, DHA promotes a healthier resolving phase, supporting better heart and kidney function in the aftermath of a heart attack.
Read More
9
DHA supports heart recovery
Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Strong focus on DHA effects
We set out to explore how docosahexaenoic acid (DHA), a beneficial omega-3 fatty acid found in fish oil and seaweed, might play a role in heart health, particularly after a heart attack. Our findings stemmed from experiments on both isolated heart cells under low oxygen conditions and live mice experiencing myocardial infarction (MI), which is the medical term for a heart attack.
The results were promising. We observed that DHA not only improved cell survival in stressed heart cells but also minimized damage in mice following a heart attack. Specifically, we noted a reduction in heart injury and a boost in heart function, highlighting DHA's potential as a protective agent.
Importantly, we found that DHA enhances autophagy—a natural process that cleans out damaged cells—by activating specific signaling pathways in the body. We established that in both our test models, the presence of DHA led to less cell death and richer heart function recovery. However, when we inhibited the autophagy process in experiments, the protective advantages of DHA were lost, underscoring its reliance on this cell-cleaning mechanism.
Our study indicates that DHA may serve as a valuable aid in healing the heart after a heart attack by promoting processes that protect against cell damage. Balancing scientific insight with real-world implications offers a promising avenue for heart health strategies, especially for those recovering from myocardial infarction.
The results were promising. We observed that DHA not only improved cell survival in stressed heart cells but also minimized damage in mice following a heart attack. Specifically, we noted a reduction in heart injury and a boost in heart function, highlighting DHA's potential as a protective agent.
Importantly, we found that DHA enhances autophagy—a natural process that cleans out damaged cells—by activating specific signaling pathways in the body. We established that in both our test models, the presence of DHA led to less cell death and richer heart function recovery. However, when we inhibited the autophagy process in experiments, the protective advantages of DHA were lost, underscoring its reliance on this cell-cleaning mechanism.
Our study indicates that DHA may serve as a valuable aid in healing the heart after a heart attack by promoting processes that protect against cell damage. Balancing scientific insight with real-world implications offers a promising avenue for heart health strategies, especially for those recovering from myocardial infarction.
Read More
Most Useful Reviews
8.8
Heart health improvement
My dad has taken this excellent supplement for years, and it aids in maintaining his heart's healthy function. A great source of omega.
Read More
8.8
Vegan omega-3 benefits
Deva Omega 3 DHA is a fantastic vegan addition to my diet. These tablets are easy to take and have noticeably improved my overall condition, which is important for eye, nervous system, and heart health. Plus, they are gluten-free and vegan-friendly. I recommend this product for anyone looking to maintain their health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
9
DHA aids post-heart attack recovery
The polyunsaturated fatty acids, EPA and DHA, ameliorate myocardial infarction-induced heart failure by inhibiting p300-HAT activity in rats.
Relevant to myocardial infarction treatments
We explored the effects of docosahexaenoic acid (DHA) on heart attack recovery in rats. The study aimed to understand how DHA, alongside eicosapentaenoic acid (EPA), can influence heart failure following myocardial infarction (MI).
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Read More
9
DHA supports heart recovery post-MI
Metabolic transformation of fat in obesity determines the inflammation resolving capacity of splenocardiac and cardiorenal networks in heart failure.
Study shows DHA's positive role
We investigated how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, influences recovery following a heart attack (MI) in the context of dietary fat intake. The study began by feeding mice with safflower oil (rich in omega-6 fatty acids) for 12 weeks, followed by DHA supplementation for another 8 weeks before inducing a heart attack.
Through this process, we observed that the early intake of safflower oil led to heightened inflammation, delaying the body’s ability to heal. However, when we supplemented with DHA, we noted a favorable shift. DHA increased the levels of specialized proresolving mediators (SPMs) that help the body resolve inflammation. These mediators seemed to counteract the negative effects of safflower oil by enhancing mechanisms in both the heart and kidneys critical for recovery post-MI.
Additionally, DHA contributed to an increase in resolving macrophages, which play a vital role in repairing the heart, and it also elevated T regulatory cells in the heart tissue during chronic heart failure. This might suggest that transitioning from a diet high in omega-6 fatty acids to one rich in omega-3s like DHA could improve outcomes after heart attacks.
Overall, while excessive safflower oil intake worsens inflammation and affects heart recovery, DHA promotes a healthier resolving phase, supporting better heart and kidney function in the aftermath of a heart attack.
Through this process, we observed that the early intake of safflower oil led to heightened inflammation, delaying the body’s ability to heal. However, when we supplemented with DHA, we noted a favorable shift. DHA increased the levels of specialized proresolving mediators (SPMs) that help the body resolve inflammation. These mediators seemed to counteract the negative effects of safflower oil by enhancing mechanisms in both the heart and kidneys critical for recovery post-MI.
Additionally, DHA contributed to an increase in resolving macrophages, which play a vital role in repairing the heart, and it also elevated T regulatory cells in the heart tissue during chronic heart failure. This might suggest that transitioning from a diet high in omega-6 fatty acids to one rich in omega-3s like DHA could improve outcomes after heart attacks.
Overall, while excessive safflower oil intake worsens inflammation and affects heart recovery, DHA promotes a healthier resolving phase, supporting better heart and kidney function in the aftermath of a heart attack.
Read More
9
DHA supports heart recovery
Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Strong focus on DHA effects
We set out to explore how docosahexaenoic acid (DHA), a beneficial omega-3 fatty acid found in fish oil and seaweed, might play a role in heart health, particularly after a heart attack. Our findings stemmed from experiments on both isolated heart cells under low oxygen conditions and live mice experiencing myocardial infarction (MI), which is the medical term for a heart attack.
The results were promising. We observed that DHA not only improved cell survival in stressed heart cells but also minimized damage in mice following a heart attack. Specifically, we noted a reduction in heart injury and a boost in heart function, highlighting DHA's potential as a protective agent.
Importantly, we found that DHA enhances autophagy—a natural process that cleans out damaged cells—by activating specific signaling pathways in the body. We established that in both our test models, the presence of DHA led to less cell death and richer heart function recovery. However, when we inhibited the autophagy process in experiments, the protective advantages of DHA were lost, underscoring its reliance on this cell-cleaning mechanism.
Our study indicates that DHA may serve as a valuable aid in healing the heart after a heart attack by promoting processes that protect against cell damage. Balancing scientific insight with real-world implications offers a promising avenue for heart health strategies, especially for those recovering from myocardial infarction.
The results were promising. We observed that DHA not only improved cell survival in stressed heart cells but also minimized damage in mice following a heart attack. Specifically, we noted a reduction in heart injury and a boost in heart function, highlighting DHA's potential as a protective agent.
Importantly, we found that DHA enhances autophagy—a natural process that cleans out damaged cells—by activating specific signaling pathways in the body. We established that in both our test models, the presence of DHA led to less cell death and richer heart function recovery. However, when we inhibited the autophagy process in experiments, the protective advantages of DHA were lost, underscoring its reliance on this cell-cleaning mechanism.
Our study indicates that DHA may serve as a valuable aid in healing the heart after a heart attack by promoting processes that protect against cell damage. Balancing scientific insight with real-world implications offers a promising avenue for heart health strategies, especially for those recovering from myocardial infarction.
Read More
8
DHA reduces heart attack risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Study relevant for heart health
We examined the effects of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, on the risk of heart attacks as part of a larger study called the VITAL trial. This extensive research involved nearly 26,000 older adults from the U.S. who were followed for an average of 5.3 years. While the initial findings from VITAL did not show significant results for major cardiovascular disease events, our re-analysis using Bayesian methods suggested a different perspective.
By incorporating evidence from previous studies, we found that daily supplementation of omega-3 fatty acids, including DHA, appears to substantially reduce the risk of coronary heart disease events. However, it is important to note that there was no observed benefit regarding stroke risk. This reinforces the idea that DHA may be particularly useful for preventing heart attacks but does not seem to impact strokes positively.
Overall, our results bolster the case for using omega-3 fatty acids in primary prevention strategies for coronary events. While we found promising results for heart attacks, we must remain cautious as these findings do not extend to strokes.
By incorporating evidence from previous studies, we found that daily supplementation of omega-3 fatty acids, including DHA, appears to substantially reduce the risk of coronary heart disease events. However, it is important to note that there was no observed benefit regarding stroke risk. This reinforces the idea that DHA may be particularly useful for preventing heart attacks but does not seem to impact strokes positively.
Overall, our results bolster the case for using omega-3 fatty acids in primary prevention strategies for coronary events. While we found promising results for heart attacks, we must remain cautious as these findings do not extend to strokes.
Read More
8
DHA as biomarker for STEMI
Combining metabolomics and OCT to reveal plasma metabolic profiling and biomarkers of plaque erosion and plaque rupture in STEMI patients.
Metabolic profiling relevance established
We explored the differences in metabolic patterns between plaque erosion (PE) and plaque rupture (PR) in patients experiencing ST-segment elevation myocardial infarction (STEMI). A total of 132 STEMI patients participated in our study, where we analyzed their plasma samples using advanced liquid chromatography and mass spectrometry techniques.
Our findings revealed that docosahexaenoic acid (DHA), along with salicylic acid and proline, could serve as valuable non-invasive biomarkers for distinguishing between PE and PR. Specifically, DHA showed promising results in our analyses, with area under the curve values of 0.81 and 0.75 in the training and test samples, respectively. This indicates that DHA could potentially play a key role in identifying the type of plaque involvement in heart attacks.
The implications of our research underscore the importance of further understanding how DHA and these other metabolites may influence outcomes in heart attack scenarios. As we continue to investigate these metabolic patterns, DHA may emerge as a significant factor in both the diagnosis and management of STEMI patients.
Our findings revealed that docosahexaenoic acid (DHA), along with salicylic acid and proline, could serve as valuable non-invasive biomarkers for distinguishing between PE and PR. Specifically, DHA showed promising results in our analyses, with area under the curve values of 0.81 and 0.75 in the training and test samples, respectively. This indicates that DHA could potentially play a key role in identifying the type of plaque involvement in heart attacks.
The implications of our research underscore the importance of further understanding how DHA and these other metabolites may influence outcomes in heart attack scenarios. As we continue to investigate these metabolic patterns, DHA may emerge as a significant factor in both the diagnosis and management of STEMI patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Heart health improvement
My dad has taken this excellent supplement for years, and it aids in maintaining his heart's healthy function. A great source of omega.
8.8
Vegan omega-3 benefits
Deva Omega 3 DHA is a fantastic vegan addition to my diet. These tablets are easy to take and have noticeably improved my overall condition, which is important for eye, nervous system, and heart health. Plus, they are gluten-free and vegan-friendly. I recommend this product for anyone looking to maintain their health.
Read More
