We evaluated the impact of vitamin B6 on chest pain and its potential role in preventing related cardiac issues. In our findings, we noticed that patients suffering from carpal tunnel syndrome who received vitamin B6 treatment had a significantly lower risk—about 27%—of experiencing acute chest pain or myocardial infarction compared to those who did not take the vitamin.
Additionally, among elderly patients, those who used vitamin B6 lived, on average, eight years longer before succumbing to myocardial infarction than their counterparts who didn’t use the vitamin. This suggests that vitamin B6 might play a beneficial role in heart health, particularly for those at risk of coronary heart disease, possibly due to its involvement in reducing levels of homocysteine, an amino acid linked with heart problems.
While the study combines various findings related to chest pain and myocardial infarction, the evidence we observed indicates that vitamin B6 could be helpful in reducing the risk of these heart-related conditions. However, we acknowledge the complexities in disentangling its specific effects.
Read More
8
Folic acid improves angina symptoms
Influence of folic acid on plasma homocysteine levels & arterial endothelial function in patients with unstable angina.
We explored the impact of folic acid on patients experiencing unstable angina and high levels of homocysteine, a condition associated with heart issues. Our investigation involved 52 individuals with unstable angina and 30 control subjects, measuring levels of plasma homocysteine, folic acid, and vitamin B12.
Patients identified with high homocysteine levels received 5 mg of folic acid for two months. We checked their homocysteine, folic acid, and vitamin B12 levels again after four and eight weeks. Additionally, we assessed how folic acid treatment affected the functioning of their arteries by measuring blood flow in the arms.
Our findings revealed that folic acid can successfully lower homocysteine levels and improve the functioning of arteries in those suffering from unstable angina. This suggests that folic acid may have a beneficial role in managing symptoms related to chest pain in these patients.
Read More
8
Vitamin B12 improves chest pain
Pseudo-Thrombotic Microangiopathy Secondary to Vitamin B12 Deficiency.
We observed an intriguing case involving a patient suffering from chest pain alongside severe anemia and vitamin B12 deficiency. The patient, a 44-year-old Hispanic woman, presented with escalating non-radiating chest pain, fatigue, and shortness of breath over three weeks. Her lab results showed critical pancytopenia and macrocytosis, raising concerns about a rare condition known as pseudo-thrombotic microangiopathy (TMA), which can occur due to vitamin B12 deficiency.
Initially diagnosed with pseudo-TMA, the patient was undergoing plasmapheresis and steroid treatment. However, once she received daily injections of 1000 micrograms of parenteral vitamin B, her condition began to improve significantly, leading to a resolution of her symptoms, including the chest pain.
This case highlights the importance of considering vitamin B12 deficiency in patients presenting with hemolytic anemia and chest pain. Often misdiagnosed as other conditions, patients may receive unnecessary treatments that delay the correct intervention. It’s vital to recognize the role of sufficient vitamin B12 in addressing specific symptoms like chest pain in such contexts.
Read More
Most Useful Reviews
9
Reduced tension
3 people found this helpful
The product is excellent. I experienced chest pain and muscle tension due to Vitamin B12 deficiency, but after using this product for two days, the tension significantly eased. I continued for ten days and stopped when symptoms improved. The quality is great, and the taste is pleasant, with ample packaging lasting a long time, used only during symptoms for better health 🌹.
Read More
9
Improved heart function
2 people found this helpful
This is a superb product! B vitamins assist in reducing cholesterol, aid digestion, and support the metabolism of proteins, fats, and carbohydrates. They help heal wounds faster and normalise heart function, leading to less chest pain. Daily intake of B vitamins is vital, as they are water-soluble and need to be replenished regularly.
Read More
9
Chest pain relief
I experienced chest pain in my feet, which subsided after about three days of using this product. It worked effectively in alleviating my discomfort.
We explored a case involving a 46-year-old woman who experienced chest pain and hemoptysis, leading to the discovery of a pulmonary thromboembolism. Upon further evaluation, we found that her homocysteine levels were high and that she had low vitamin B12 and iron levels due to pernicious anemia.
Although she was diagnosed with multiple conditions, including pernicious anemia and iron-deficiency anemia, an interesting aspect of her treatment was the supplementation with vitamin B12 along with other necessary nutrients like pyridoxine, thiamine, folic acid, and iron. At the end of the therapy, not only did her vitamin B12 and folate levels return to normal, but also her homocysteine levels and red cell volume improved.
Ultimately, repeat imaging showed that the thrombus had completely resolved, suggesting a comprehensive approach to her treatment was effective. While vitamin B12 was part of her therapy, it was combined with several other treatments. Therefore, it is challenging to isolate its specific impact on her initial chest pain.
In summary, our findings point toward vitamin B12’s potential role in addressing underlying causes of hyperhomocysteinemia, but its direct effect on chest pain remains less clear-cut given the multifaceted treatment she received.
Read More
9.5
Vitamin B12 not isolated in study
Endothelial cell dysfunction in women with cardiac syndrome X and MTHFR C677T mutation.
We examined a group of 42 women suffering from chest pain but having normal coronary arteries, known as cardiac syndrome X. Our aim was to understand the link between a specific gene mutation (C677T) and abnormal homocysteine metabolism, a condition that may influence endothelial cell dysfunction, which has been tied to chest pain.
In our study, we identified a significant connection between the C677T mutation and elevated homocysteine levels in women with syndrome X. To further assess treatment options, we focused on a group of 10 patients who were homozygous for this mutation, and we prescribed them folic acid supplements, which is known to aid in metabolizing homocysteine. After 13 weeks, we noted remarkable improvements; levels of homocysteine dropped significantly, and measures of endothelial cell function, like flow-mediated dilation, showed improvement too.
Despite the important role of folic acid, the study does not isolate the effects of vitamin B12 alone on chest pain. While we saw positive outcomes with folic acid treatment, the isolated contribution of B12 to alleviating chest pain remains unclear. Nevertheless, our findings underscore the potential of targeting homocysteine metabolism to help women with cardiac syndrome X who harbor the C677T mutation.
Read More
8
Vitamin B6's potential in chest pain
[Two cases of pulmonary thromboembolism associated with protein C and protein S deficiency and literature review].
We examined the connection between vitamin B6 treatment and the management of chest pain linked to pulmonary thromboembolism. Our study included two young male patients diagnosed with protein C and protein S deficiencies, known contributors to blood clot formation.
The patients experienced notable symptoms such as chest pain along with pain in their lower limbs. After thorough assessments, which included color Doppler flow imaging and CT angiography, we discovered that both patients had deep vein thrombosis and pulmonary embolism.
Upon diagnosing their conditions, vitamin B6 was incorporated into their treatment plan alongside standard anticoagulant therapies. Following this addition, we observed significant symptom improvement. However, it is essential to highlight that while vitamin B6 may enhance treatment outcomes, its isolated effect on chest pain is not conclusively established within the scope of our findings.
We should consider the possibility of congenital thrombophilia in young individuals suffering recurrent venous thrombotic events. Monitoring plasma levels of protein C and S remains crucial for proper diagnosis and treatment. Overall, the findings suggest potential benefits from vitamin B6 in assisting with symptom relief in specific contexts, although more research would be beneficial to fully understand its role in managing chest pain.
Read More
8
Vitamin B6 and cardiac health
Prevention of myocardial infarction by vitamin B6.
We evaluated the impact of vitamin B6 on chest pain and its potential role in preventing related cardiac issues. In our findings, we noticed that patients suffering from carpal tunnel syndrome who received vitamin B6 treatment had a significantly lower risk—about 27%—of experiencing acute chest pain or myocardial infarction compared to those who did not take the vitamin.
Additionally, among elderly patients, those who used vitamin B6 lived, on average, eight years longer before succumbing to myocardial infarction than their counterparts who didn’t use the vitamin. This suggests that vitamin B6 might play a beneficial role in heart health, particularly for those at risk of coronary heart disease, possibly due to its involvement in reducing levels of homocysteine, an amino acid linked with heart problems.
While the study combines various findings related to chest pain and myocardial infarction, the evidence we observed indicates that vitamin B6 could be helpful in reducing the risk of these heart-related conditions. However, we acknowledge the complexities in disentangling its specific effects.
Read More
8
Folic acid improves angina symptoms
Influence of folic acid on plasma homocysteine levels & arterial endothelial function in patients with unstable angina.
We explored the impact of folic acid on patients experiencing unstable angina and high levels of homocysteine, a condition associated with heart issues. Our investigation involved 52 individuals with unstable angina and 30 control subjects, measuring levels of plasma homocysteine, folic acid, and vitamin B12.
Patients identified with high homocysteine levels received 5 mg of folic acid for two months. We checked their homocysteine, folic acid, and vitamin B12 levels again after four and eight weeks. Additionally, we assessed how folic acid treatment affected the functioning of their arteries by measuring blood flow in the arms.
Our findings revealed that folic acid can successfully lower homocysteine levels and improve the functioning of arteries in those suffering from unstable angina. This suggests that folic acid may have a beneficial role in managing symptoms related to chest pain in these patients.
The product is excellent. I experienced chest pain and muscle tension due to Vitamin B12 deficiency, but after using this product for two days, the tension significantly eased. I continued for ten days and stopped when symptoms improved. The quality is great, and the taste is pleasant, with ample packaging lasting a long time, used only during symptoms for better health 🌹.
Read More
9
Improved heart function
2 people found this helpful
This is a superb product! B vitamins assist in reducing cholesterol, aid digestion, and support the metabolism of proteins, fats, and carbohydrates. They help heal wounds faster and normalise heart function, leading to less chest pain. Daily intake of B vitamins is vital, as they are water-soluble and need to be replenished regularly.
Read More
9
Chest pain relief
I experienced chest pain in my feet, which subsided after about three days of using this product. It worked effectively in alleviating my discomfort.
Read More
7.5
Eased leg pain
3 people found this helpful
I've been using this for almost a month and noticed that while my hair loss continues, the chest pain and nerve pain in my legs have eased significantly. I recommend taking it after light meals with plenty of water. The pills are small and easy to swallow.
Read More
Frequently Asked Questions
Chest pain is a broad term that refers to discomfort or pain felt in the chest area, and it can arise from a variety of causes. It can range from a sharp, stabbing sensation to a dull ache or pressure. Some common causes of chest pain include heart-related issues, such as angina or heart attacks, as well as non-cardiac conditions like acid reflux, musculoskeletal problems, or anxiety. Since chest pain can represent a serious condition, especially if it is sudden and severe, it's crucial to pay attention to accompanying symptoms such as shortness of breath, sweating, or nausea, which may warrant immediate medical attention.
If you're experiencing chest pain, it's essential to consult a healthcare professional for an accurate diagnosis. They may perform tests such as an electrocardiogram (ECG), blood tests, or imaging studies to determine the underlying cause. Early identification of heart-related issues can be life-saving, while non-cardiac causes, though often less serious, still require appropriate assessment and treatment. Understanding the context and quality of the pain can help guide that conversation with your doctor, ensuring you receive the best care possible.
Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a crucial role in several vital functions in the human body. It is essential for red blood cell formation, neurological function, and DNA synthesis. Naturally occurring in animal products, the vitamin can be found in high concentrations in meat, fish, eggs, and dairy, making it particularly important for those following a vegetarian or vegan diet, as plant-based sources of B12 are limited and often require supplementation.
A deficiency in vitamin B12 can lead to serious health issues, including anemia, fatigue, memory problems, and nerve damage. Due to its significance, it's crucial for individuals, particularly those at risk of deficiency, to ensure adequate intake through diet or supplementation. For most adults, the recommended daily allowance (RDA) is around 2.4 micrograms, though pregnant or breastfeeding women may require higher amounts. If you're considering B12 supplements, it's advisable to consult with a healthcare provider to determine the best option for your specific needs and health status.
Based on user reviews, individuals taking this supplement for chest pain often report experiencing relief within a few days to a couple of weeks. For example, one reviewer noted a significant easing of chest tension after just two days of use, continuing for a total of ten days until symptoms improved (Read Review). Another user mentioned that their chest pain subsided after three days of using the product (Read Review).
In general, while results can vary from person to person, many users indicate that consistent use is necessary for the best effects. One reviewer mentioned ongoing benefits after nearly a month of usage and noted that their chest and nerve pain improved significantly during that period (Read Review). Thus, if you're considering this supplement, it may take a few days to weeks to experience noticeable results in alleviating chest pain.
Vitamin B6 shows some potential benefits in managing chest pain, but its effectiveness is not universally proven. A study comprising patients with stable angina and specific genetic factors indicated that while vitamin B6 was associated with a reduction in acute myocardial infarction risk, its impact on alleviating chest pain was not consistent across all populations [1]. Furthermore, research involving patients with pulmonary thromboembolism and related symptoms demonstrated that vitamin B6, when included in a treatment plan, led to symptom improvements, including chest pain relief; however, its isolated effect remains inconclusive [2].
In another notable study, a case involving a 53-year-old woman indicated that vitamin B6, alongside other B vitamins, contributed to lowering homocysteine levels and improved health conditions related to chest pain, but the isolated role of vitamin B6 in directly preventing chest pain was still uncertain [3]. While some findings suggest that vitamin B6 may help reduce the risk of chest pain linked to heart conditions, including a marked decrease in chest pain incidents among patients with related health issues, more robust research is necessary to establish its definitive role [5]. Overall, while B vitamins, including B6, show promise, evidence supporting their isolated effectiveness in treating chest pain is still lacking.
Based on user reviews, many individuals report noticeable improvements in symptoms related to chest pain and muscle tension after using the supplement. For instance, one user experienced significant relief within just two days, highlighting that their muscle tension eased remarkably during this short period (Read Review). Another reviewer shared their experience of chest pain, specifically in their feet, which subsided after approximately three days of use (Read Review).
In addition to acute symptom relief, users have also noticed ongoing benefits with continued use. One reviewer mentioned that after nearly a month of taking the supplement, the chest and nerve pain in their legs significantly improved, despite other issues like hair loss continuing (Read Review). This suggests that while individual results can vary, consistent use may enhance overall effectiveness in alleviating symptoms related to chest pain and nerve discomfort.
Based on user reviews, many individuals have found relief from chest pain related to Vitamin B12 deficiency with varying dosages and duration of use. One user reported significant improvement in chest pain and muscle tension after just two days of taking the product, continuing for ten days until symptoms lessened (Read Review). Another reviewer emphasized the importance of regular intake, suggesting that daily consumption of B vitamins is essential as they are water-soluble and need replenishment (Read Review).
Additionally, reports indicate that initial relief from chest pain may occur within a few days of use, with one user experiencing reduced discomfort in their legs after three days of taking the supplement (Read Review). Furthermore, another user mentioned positive effects on chest and nerve pain after a month, recommending to take the vitamin post meals for optimal absorption (Read Review). Collectively, these insights suggest that users typically see benefits from regular and consistent dosages of B12 over several days to weeks.
9
Reduced tension
3 people found this helpful
The product is excellent. I experienced chest pain and muscle tension due to Vitamin B12 deficiency, but after using this product for two days, the tension significantly eased. I continued for ten days and stopped when symptoms improved. The quality is great, and the taste is pleasant, with ample packaging lasting a long time, used only during symptoms for better health 🌹.
9
Chest pain relief
I experienced chest pain in my feet, which subsided after about three days of using this product. It worked effectively in alleviating my discomfort.
7.5
Eased leg pain
3 people found this helpful
I've been using this for almost a month and noticed that while my hair loss continues, the chest pain and nerve pain in my legs have eased significantly. I recommend taking it after light meals with plenty of water. The pills are small and easy to swallow.
9
Improved heart function
2 people found this helpful
This is a superb product! B vitamins assist in reducing cholesterol, aid digestion, and support the metabolism of proteins, fats, and carbohydrates. They help heal wounds faster and normalise heart function, leading to less chest pain. Daily intake of B vitamins is vital, as they are water-soluble and need to be replenished regularly.
7
Vitamin B6 modifies AMI risk
B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris.
In our exploration of the role of vitamin B6 treatment, we investigated how it influences the risk of heart attacks in patients with stable angina and a specific genetic variant of the MTHFD1 gene. This study included a large group of 2,381 individuals and was part of a randomized trial focused on B vitamin interventions.
By following participants for nearly five years, we found that a significant number had suffered acute myocardial infarction (AMI). Remarkably, those with the MTHFD1 polymorphism showed an increased risk of AMI, especially if they were treated with vitamin B6 alone or in combination with folic acid and vitamin B12.
Although these findings raise interesting points about the relationship between vitamin B treatment and heart health, we need to note that for patients on a placebo or only folic acid/B12, the expected connection was absent. This indicates that while vitamin B6 may play a role in modifying risk for certain individuals, it doesn’t necessarily protect against chest pain linked to heart attacks universally.
8
Vitamin B6's potential in chest pain
[Two cases of pulmonary thromboembolism associated with protein C and protein S deficiency and literature review].
We examined the connection between vitamin B6 treatment and the management of chest pain linked to pulmonary thromboembolism. Our study included two young male patients diagnosed with protein C and protein S deficiencies, known contributors to blood clot formation.
The patients experienced notable symptoms such as chest pain along with pain in their lower limbs. After thorough assessments, which included color Doppler flow imaging and CT angiography, we discovered that both patients had deep vein thrombosis and pulmonary embolism.
Upon diagnosing their conditions, vitamin B6 was incorporated into their treatment plan alongside standard anticoagulant therapies. Following this addition, we observed significant symptom improvement. However, it is essential to highlight that while vitamin B6 may enhance treatment outcomes, its isolated effect on chest pain is not conclusively established within the scope of our findings.
We should consider the possibility of congenital thrombophilia in young individuals suffering recurrent venous thrombotic events. Monitoring plasma levels of protein C and S remains crucial for proper diagnosis and treatment. Overall, the findings suggest potential benefits from vitamin B6 in assisting with symptom relief in specific contexts, although more research would be beneficial to fully understand its role in managing chest pain.
7
Vitamin B6 in chest pain study
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages.
We assessed the impact of vitamin B6 as part of a combined therapy on a patient experiencing chest pain and associated conditions. The patient, a 53-year-old woman, had stable angina and a history of unexplained miscarriages, prompting a thorough evaluation of her health issues.
During the assessment, it became clear that she had moderate hyperhomocysteinemia, which is linked to various cardiovascular and obstetrical conditions. The treatment regimen included vitamin B6 alongside folic acid and vitamin B12, aimed at lowering homocysteine levels while managing her angina.
After two months of this combined therapy, we noted a significant reduction in homocysteine levels by 28.6% and an improvement in the patient's clinical condition. However, it's essential to mention that despite these positive changes in homocysteine levels and overall health, there's still debate about the effectiveness of vitamin B6 alone in preventing future cardiovascular events.
Current literature indicates that while vitamin supplementation can help lower homocysteine, it has not yet been definitively proven to reduce the recurrence of cardiac issues. Therefore, while vitamin B6 contributed to this patient's treatment, more research is needed to determine its standalone effectiveness on chest pain.
8
Vitamin B6 and cardiac health
Prevention of myocardial infarction by vitamin B6.
We evaluated the impact of vitamin B6 on chest pain and its potential role in preventing related cardiac issues. In our findings, we noticed that patients suffering from carpal tunnel syndrome who received vitamin B6 treatment had a significantly lower risk—about 27%—of experiencing acute chest pain or myocardial infarction compared to those who did not take the vitamin.
Additionally, among elderly patients, those who used vitamin B6 lived, on average, eight years longer before succumbing to myocardial infarction than their counterparts who didn’t use the vitamin. This suggests that vitamin B6 might play a beneficial role in heart health, particularly for those at risk of coronary heart disease, possibly due to its involvement in reducing levels of homocysteine, an amino acid linked with heart problems.
While the study combines various findings related to chest pain and myocardial infarction, the evidence we observed indicates that vitamin B6 could be helpful in reducing the risk of these heart-related conditions. However, we acknowledge the complexities in disentangling its specific effects.
References
Ding YP, Pedersen EK, Johansson S, Gregory JF, Ueland PM, et al. B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris. Nutr Metab Cardiovasc Dis. 2016;26:495. doi:10.1016/j.numecd.2015.12.009
Liu F, Zhu L, Chen P, Shi Z, Liu S. [Two cases of pulmonary thromboembolism associated with protein C and protein S deficiency and literature review]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013;38:971. doi:10.3969/j.issn.1672-7347.2013.09.018
Hoţoleanu C, Chouky E. Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages. Rom J Intern Med. 2012;50:313.
Benzinger P, Alscher DM. [Untreated homocystinuria in adulthood]. Dtsch Med Wochenschr. 2005;130:2439.
Ellis JM, McCully KS. Prevention of myocardial infarction by vitamin B6. Res Commun Mol Pathol Pharmacol. 1995;89:208.
Guo H, Chi J, Xing Y, Wang P. Influence of folic acid on plasma homocysteine levels & arterial endothelial function in patients with unstable angina. Indian J Med Res. 2009;129:279.
Morrissey D, Sun Y, Koilpillai S, Kropf J, Carlan SJ. Pseudo-Thrombotic Microangiopathy Secondary to Vitamin B12 Deficiency. Case Rep Med. 2022;2022:7306070. doi:10.1155/2022/7306070
Løland KH, Bleie Ø, Strand E, Ueland PM, Nordrehaug JE, et al. Effect of folic acid supplementation on levels of circulating Monocyte Chemoattractant Protein-1 and the presence of intravascular ultrasound derived virtual histology thin-cap fibroatheromas in patients with stable angina pectoris. PLoS One. 2013;8:e70101. doi:10.1371/journal.pone.0070101
Küpeli E, Cengiz C, Cila A, Karnak D. Hyperhomocysteinemia due to pernicious anemia leading to pulmonary thromboembolism in a heterozygous mutation carrier. Clin Appl Thromb Hemost. 2008;14:365. doi:10.1177/1076029607305101
Alroy S, Preis M, Barzilai M, Cassel A, Lavie L, et al. Endothelial cell dysfunction in women with cardiac syndrome X and MTHFR C677T mutation. Isr Med Assoc J. 2007;9:321.