Last update
5/10/2026
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8.3
Supplement Facts
Serving Size: 1 Veggie Capsule
Serving Per Container: 60
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
200 mg
†
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg
†
Top Medical Research Studies
9
In examining the impact of coenzyme Q10 on muscle pain linked to statin use, we found promising results. Fifty participants experiencing mild-to-moderate muscle symptoms received either coenzyme Q10 or a placebo for 30 days.
Using validated pain questionnaires, we observed significant reductions in both pain severity and interference in daily activities among those taking coenzyme Q10. Notably, 75% of participants reported relief from their symptoms. However, no changes were found in blood tests, indicating no adverse effects.
Using validated pain questionnaires, we observed significant reductions in both pain severity and interference in daily activities among those taking coenzyme Q10. Notably, 75% of participants reported relief from their symptoms. However, no changes were found in blood tests, indicating no adverse effects.
Read More
8
We investigated the impact of Coenzyme Q10 (CoQ10) in patients who struggled with muscle pain related to statin use. Sixty participants first paused their statins for a month, then were given either CoQ10 or a placebo for three months.
Our findings revealed that those taking CoQ10 reported less muscle pain compared to the placebo group. The clinical measures showed significant improvements in symptoms such as myalgia. Overall, CoQ10 appears beneficial for managing statin-associated muscle discomfort.
Our findings revealed that those taking CoQ10 reported less muscle pain compared to the placebo group. The clinical measures showed significant improvements in symptoms such as myalgia. Overall, CoQ10 appears beneficial for managing statin-associated muscle discomfort.
Read More
7
We analyzed the impact of Coenzyme Q10 (CoQ10) on muscle pain in patients using statins, based on data from seven randomized controlled trials. Through our review, we found that CoQ10 significantly lessened muscle pain in patients experiencing statin-associated muscle symptoms (SAMS).
While four trials showed a noticeable reduction in pain intensity, three did not exhibit significant changes. Overall, this suggests that CoQ10 supplementation could be beneficial for those struggling with muscle discomfort due to statin use, though further research is essential to bolster these findings.
While four trials showed a noticeable reduction in pain intensity, three did not exhibit significant changes. Overall, this suggests that CoQ10 supplementation could be beneficial for those struggling with muscle discomfort due to statin use, though further research is essential to bolster these findings.
Read More
Most Useful Reviews
8
Muscle pain relief
3 people found this helpful
A wonderful product I used two years ago. I had a fast heart rate and muscle pain, but after using it, praise be to God, everything improved.
Read More
10
Migraine improvement
1 people found this helpful
Excellent and useful product. I previously suffered from general fatigue and muscle pain, but all of that has disappeared. My migraine also improved significantly, nearly resolving after using this product.
Read More
6
Uncertain benefits
1 people found this helpful
CoQ10 offers a neutralising effect on my pain from inflammation. While I initially thought I had heart issues, I’ve been taking it for over a year. It may help my myalgia and costochondritis, as missing a few days brings a tightening in my chest.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
- All Researches
9
In examining the impact of coenzyme Q10 on muscle pain linked to statin use, we found promising results. Fifty participants experiencing mild-to-moderate muscle symptoms received either coenzyme Q10 or a placebo for 30 days.
Using validated pain questionnaires, we observed significant reductions in both pain severity and interference in daily activities among those taking coenzyme Q10. Notably, 75% of participants reported relief from their symptoms. However, no changes were found in blood tests, indicating no adverse effects.
Using validated pain questionnaires, we observed significant reductions in both pain severity and interference in daily activities among those taking coenzyme Q10. Notably, 75% of participants reported relief from their symptoms. However, no changes were found in blood tests, indicating no adverse effects.
Read More
8
We investigated the impact of Coenzyme Q10 (CoQ10) in patients who struggled with muscle pain related to statin use. Sixty participants first paused their statins for a month, then were given either CoQ10 or a placebo for three months.
Our findings revealed that those taking CoQ10 reported less muscle pain compared to the placebo group. The clinical measures showed significant improvements in symptoms such as myalgia. Overall, CoQ10 appears beneficial for managing statin-associated muscle discomfort.
Our findings revealed that those taking CoQ10 reported less muscle pain compared to the placebo group. The clinical measures showed significant improvements in symptoms such as myalgia. Overall, CoQ10 appears beneficial for managing statin-associated muscle discomfort.
Read More
8
We explored the use of coenzyme Q10 (CoQ10) combined with plant polyprenols to address muscle pain in patients suffering from statin-induced myopathy. In our open-label study, 14 participants took 4mg of polyprenols and 100mg of CoQ10 daily for eight weeks.
While safety was generally maintained, we observed significant improvements in muscle pain and weakness among participants. Notably, two patients reported complete relief from muscle pain, showcasing potential benefits.
However, the study’s findings also indicate the need for more extensive research to fully understand the effects.
While safety was generally maintained, we observed significant improvements in muscle pain and weakness among participants. Notably, two patients reported complete relief from muscle pain, showcasing potential benefits.
However, the study’s findings also indicate the need for more extensive research to fully understand the effects.
Read More
7
We analyzed the impact of Coenzyme Q10 (CoQ10) on muscle pain in patients using statins, based on data from seven randomized controlled trials. Through our review, we found that CoQ10 significantly lessened muscle pain in patients experiencing statin-associated muscle symptoms (SAMS).
While four trials showed a noticeable reduction in pain intensity, three did not exhibit significant changes. Overall, this suggests that CoQ10 supplementation could be beneficial for those struggling with muscle discomfort due to statin use, though further research is essential to bolster these findings.
While four trials showed a noticeable reduction in pain intensity, three did not exhibit significant changes. Overall, this suggests that CoQ10 supplementation could be beneficial for those struggling with muscle discomfort due to statin use, though further research is essential to bolster these findings.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
8
Muscle pain relief
3 people found this helpful
A wonderful product I used two years ago. I had a fast heart rate and muscle pain, but after using it, praise be to God, everything improved.
Read More
10
Migraine improvement
1 people found this helpful
Excellent and useful product. I previously suffered from general fatigue and muscle pain, but all of that has disappeared. My migraine also improved significantly, nearly resolving after using this product.
Read More
6
Uncertain benefits
1 people found this helpful
CoQ10 offers a neutralising effect on my pain from inflammation. While I initially thought I had heart issues, I’ve been taking it for over a year. It may help my myalgia and costochondritis, as missing a few days brings a tightening in my chest.
Read More
10
Muscle pain elimination
After experiencing muscle pain from cholesterol medication, I learned about CoQ10. This supplement completely eliminated my muscle pain.
Read More
10
Statin side effects
The highest concentration I found in Israel is 100 mg, but here I have 200 mg per capsule. As a long-term statin user, this helps me immensely; I have no muscle pain.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Kovacic S, Habicht SD, Eckert GP. Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis. J Nutr Sci. 2025;14:e72. 10.1017/jns.2025.10043
- Derosa G, D'Angelo A, Maffioli P. Coenzyme q10 liquid supplementation in dyslipidemic subjects with statin-related clinical symptoms: a double-blind, randomized, placebo-controlled study. Drug Des Devel Ther. 2019;13:3647. 10.2147/DDDT.S223153
- Latkovskis G, Saripo V, Sokolova E, Upite D, Vanaga I, et al. Pilot study of safety and efficacy of polyprenols in combination with coenzyme Q10 in patients with statin-induced myopathy. Medicina (Kaunas). 2016;52:171. 10.1016/j.medici.2016.05.002
- Skarlovnik A, Janić M, Lunder M, Turk M, Šabovič M. Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Med Sci Monit. 2014;20:2183. 10.12659/MSM.890777
