Last update
5/10/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Ineffective
Based on 2 Researches
4.8
USERS' SCORE
Good
Based on 7 Reviews
8.3
Supplement Facts
Serving Size: 1 Veggie Capsule
Serving Per Container: 60
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
200 mg
†
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg
†
Top Medical Research Studies
0
CoQ10 ineffective for mitochondrial sleep apnea
We examined a rare case of mitochondrial encephalomyopathy featuring multiple complications including sleep apnea, cerebellar ataxia, and peripheral neuropathy—a combination never before documented in medical literature. The patient received six months of coenzyme Q10 therapy to address the underlying mitochondrial dysfunction.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Read More
9.5
Coenzyme Q10 in sleep apnea study
We explored the impact of various treatments, including coenzyme Q10, on obstructive sleep apnea (OSA) in a patient with adult-onset Leigh disease. This condition often presents with severe neurological symptoms, complicating the patients’ overall health and quality of life.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
Read More
Most Useful Reviews
9
Increased energy
1 people found this helpful
A potent antioxidant! After a week of taking it, I feel more energetic, and my sleep has improved dramatically without any side effects. I plan to continue this for optimal heart and brain support.
Read More
9
Normalised heart rate
1 people found this helpful
This high-absorption coenzyme truly works wonders! For years, I suffered from sleep disturbances and an irregular heart rhythm at night. Since taking this, those issues have disappeared. The results are evident.
Read More
9
Energy boost
I’m now addicted to Qemwinter! I feel full of energy and don’t feel the need to sleep. I recommend taking it in the morning for sustained energy throughout the day.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Ineffective
Based on 2 Researches
4.8
- All Researches
9.5
Coenzyme Q10 in sleep apnea study
We explored the impact of various treatments, including coenzyme Q10, on obstructive sleep apnea (OSA) in a patient with adult-onset Leigh disease. This condition often presents with severe neurological symptoms, complicating the patients’ overall health and quality of life.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
Read More
0
CoQ10 ineffective for mitochondrial sleep apnea
We examined a rare case of mitochondrial encephalomyopathy featuring multiple complications including sleep apnea, cerebellar ataxia, and peripheral neuropathy—a combination never before documented in medical literature. The patient received six months of coenzyme Q10 therapy to address the underlying mitochondrial dysfunction.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Increased energy
1 people found this helpful
A potent antioxidant! After a week of taking it, I feel more energetic, and my sleep has improved dramatically without any side effects. I plan to continue this for optimal heart and brain support.
Read More
9
Normalised heart rate
1 people found this helpful
This high-absorption coenzyme truly works wonders! For years, I suffered from sleep disturbances and an irregular heart rhythm at night. Since taking this, those issues have disappeared. The results are evident.
Read More
9
Energy boost
I’m now addicted to Qemwinter! I feel full of energy and don’t feel the need to sleep. I recommend taking it in the morning for sustained energy throughout the day.
Read More
7.5
Youthfulness restored
For menopausal women, Q10 is fantastic for preventing ageing. After one bottle, my skin looks better, my energy has increased, and I sleep well. It’s perfect.
Read More
7.5
Mood enhancement
4 people found this helpful
I recommend this as it has significantly increased my energy and mood. My sleep quality has also improved, leaving me well-rested upon waking.
Read More
Frequently Asked Questions
9
Increased energy
1 people found this helpful
A potent antioxidant! After a week of taking it, I feel more energetic, and my sleep has improved dramatically without any side effects. I plan to continue this for optimal heart and brain support.
7.5
Relieved soreness
1 people found this helpful
After a few days, my family noticed improved sleep and reduced soreness in their calves. I'm excited for even better results!
9
Normalised heart rate
1 people found this helpful
This high-absorption coenzyme truly works wonders! For years, I suffered from sleep disturbances and an irregular heart rhythm at night. Since taking this, those issues have disappeared. The results are evident.
7.5
Mood enhancement
4 people found this helpful
I recommend this as it has significantly increased my energy and mood. My sleep quality has also improved, leaving me well-rested upon waking.
9.5
Coenzyme Q10 in sleep apnea study
We explored the impact of various treatments, including coenzyme Q10, on obstructive sleep apnea (OSA) in a patient with adult-onset Leigh disease. This condition often presents with severe neurological symptoms, complicating the patients’ overall health and quality of life.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
References
- Tatsumi C, Takahashi M, Yorifuji S, Nishikawa Y, Kitaguchi M, et al. Mitochondrial encephalomyopathy with sleep apnea. Eur Neurol. 1988;28:64. PubMed
- Mermigkis C, Bouloukaki I, Mastorodemos V, Plaitakis A, Alogdianakis V, et al. Medical treatment with thiamine, coenzyme Q, vitamins E and C, and carnitine improved obstructive sleep apnea in an adult case of Leigh disease. Sleep Breath. 2013;17:1129. 10.1007/s11325-013-0816-5
