Can Doctor's Best High Absorption Zinc Bisglycinate Help with High Cholesterol?
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.5
Supplement Facts
Serving Size: 1 Veggie Capsule
Serving Per Container: 90
Amount Per Serving
%DV
Zinc (as zinc bisglycinate chelate) (Albion®)
50 mg
455%
Top Medical Research Studies
9
Zinc improves cholesterol levels
Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
Zinc, cholesterol, and heart health
Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study.
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
Zinc's variable impact on cholesterol
Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus.
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More
Most Useful Reviews
9
Symptoms resolved
1 people found this helpful
The best zinc supplement available! This amazing product is highly bioavailable and offers superior absorption. All my symptoms of low zinc disappeared after just a few weeks of use (such as white spots on my nails, weak immune system, and poor wound healing). The capsules are small, easy to take, and free from unnecessary fillers. I adore all of Doctor's Best products!
Read More
9
Improved senses
4 people found this helpful
Excellent! Zinc is in a formula that is easily absorbed by the body and comes in a high dose. I provided it for my relatives when they were infected with COVID-19. Within just five days, they noticed a difference, and thankfully their sense of smell and taste returned after some time, thanks to the formula. This dose is therapeutic. Please be cautious with your body and avoid taking anything you do not understand, as it may lead to unavoidable problems. 🙏🏻
Read More
7.5
Skin condition improved
1 people found this helpful
Doctor's Best Zinc Bisglycinate boasts high absorption and is an excellent supplement for boosting immunity and skin health. After using it for a few weeks, I observed an enhancement in my skin condition and stronger nails. The vegetarian capsules are convenient to take, and the chelated form ensures a high level of absorption.
Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
Zinc's variable impact on cholesterol
Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus.
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More
8
Zinc, cholesterol, and heart health
Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study.
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
Study on zinc and cholesterol outcomes
Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial.
We conducted a randomized clinical trial involving 75 patients with type 2 diabetes to explore the effects of a nutraceutical combination containing myo-inositol, d-chiro-inositol, α-lactalbumin, Gymnema sylvestre, and zinc on cholesterol levels.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
Read More
7
Zinc's role in cholesterol management
The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats.
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.5
All Reviews
Positive Reviews
Negative Reviews
9
Symptoms resolved
1 people found this helpful
The best zinc supplement available! This amazing product is highly bioavailable and offers superior absorption. All my symptoms of low zinc disappeared after just a few weeks of use (such as white spots on my nails, weak immune system, and poor wound healing). The capsules are small, easy to take, and free from unnecessary fillers. I adore all of Doctor's Best products!
Read More
9
Improved senses
4 people found this helpful
Excellent! Zinc is in a formula that is easily absorbed by the body and comes in a high dose. I provided it for my relatives when they were infected with COVID-19. Within just five days, they noticed a difference, and thankfully their sense of smell and taste returned after some time, thanks to the formula. This dose is therapeutic. Please be cautious with your body and avoid taking anything you do not understand, as it may lead to unavoidable problems. 🙏🏻
Read More
7.5
Skin condition improved
1 people found this helpful
Doctor's Best Zinc Bisglycinate boasts high absorption and is an excellent supplement for boosting immunity and skin health. After using it for a few weeks, I observed an enhancement in my skin condition and stronger nails. The vegetarian capsules are convenient to take, and the chelated form ensures a high level of absorption.
Read More
Frequently Asked Questions
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc plays a crucial role in various bodily functions, including immune system support and wound healing, but its effect on cholesterol levels is not well-established. Some studies suggest that zinc may have a modest impact on lipid profiles, including potentially lowering levels of total cholesterol and triglycerides. However, these findings are not conclusive enough to recommend zinc supplementation as a primary treatment for high cholesterol.
If you're considering zinc supplements for cholesterol management, it's essential to consult with a healthcare professional first. They can provide personalized guidance based on your individual health needs and suggest more established lifestyle changes, such as a balanced diet and regular exercise, which are proven strategies for managing cholesterol levels effectively. Remember that while supplements can support health in specific areas, they should not replace conventional treatment methods prescribed by your doctor.
Zinc supplementation shows some potential in managing cholesterol levels, particularly for individuals with conditions like type 2 diabetes. A randomized, placebo-controlled study indicated that patients taking zinc experienced significant reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, with average reductions of 25.06 mg/dL and 22.2 mg/dL, respectively [1]. Additionally, a comprehensive review of multiple trials (covering 1,357 participants) found that zinc supplementation led to decreases in total cholesterol and LDL levels, alongside improvements in high-density lipoprotein (HDL) cholesterol [4].
However, the evidence is not entirely conclusive. Other studies highlighted that while there are correlations between zinc intake and heart health, particularly concerning coronary artery disease, the need for further research to understand these relationships better is essential [2]. It's worth noting that while some studies have pointed out potential benefits, others have suggested that zinc alone might not produce significant changes in cholesterol levels, especially in different dietary contexts [3]. Therefore, while zinc could serve as a complementary strategy for cholesterol management, more targeted research is needed to establish its effectiveness firmly.
Users report noticeable improvements in various symptoms related to low zinc levels after using Doctor's Best Zinc Bisglycinate. For instance, one user mentioned that all symptoms including white spots on nails, a weak immune system, and poor wound healing completely disappeared within a few weeks of use Read Review. Another user shared a positive experience with family members who were recovering from COVID-19, highlighting that their sense of smell and taste returned after five days of supplementation, indicating a beneficial impact on recovery Read Review. Additionally, some users noted enhancements in skin health and stronger nails after a few weeks of use, showcasing both cosmetic and health-related benefits Read Review.
According to recent research, the optimal dose of zinc for managing high cholesterol, particularly in individuals with type 2 diabetes, appears to be around 50 mg per day. A study conducted on patients specifically diagnosed with type 2 diabetes indicated that this dose led to a significant reduction in low-density lipoprotein (LDL) cholesterol and triglycerides, with LDL cholesterol dropping by an average of 25.06 mg/dL ([1]). Moreover, an analysis reviewing multiple randomized controlled trials involving zinc supplementation also reported reductions in triglycerides, total cholesterol, and LDL-C, reinforcing the idea that a daily intake in the range of 50 mg could be effective for improving cholesterol levels ([4]).
It’s crucial to note that while zinc supplementation may offer valuable benefits for cholesterol management, the effects can vary, and it doesn’t significantly affect high-density lipoprotein (HDL) cholesterol—often referred to as "good" cholesterol. Therefore, while increasing dietary zinc intake may be beneficial, its role in broadly addressing cholesterol levels is still being studied and further exploration is necessary to validate these findings and ascertain the best approaches for incorporating zinc into dietary plans for effective cholesterol management ([3]).
9
Symptoms resolved
1 people found this helpful
The best zinc supplement available! This amazing product is highly bioavailable and offers superior absorption. All my symptoms of low zinc disappeared after just a few weeks of use (such as white spots on my nails, weak immune system, and poor wound healing). The capsules are small, easy to take, and free from unnecessary fillers. I adore all of Doctor's Best products!
9
Improved senses
4 people found this helpful
Excellent! Zinc is in a formula that is easily absorbed by the body and comes in a high dose. I provided it for my relatives when they were infected with COVID-19. Within just five days, they noticed a difference, and thankfully their sense of smell and taste returned after some time, thanks to the formula. This dose is therapeutic. Please be cautious with your body and avoid taking anything you do not understand, as it may lead to unavoidable problems. 🙏🏻
7.5
Skin condition improved
1 people found this helpful
Doctor's Best Zinc Bisglycinate boasts high absorption and is an excellent supplement for boosting immunity and skin health. After using it for a few weeks, I observed an enhancement in my skin condition and stronger nails. The vegetarian capsules are convenient to take, and the chelated form ensures a high level of absorption.
8
Zinc's variable impact on cholesterol
Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus.
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
9
Zinc improves cholesterol levels
Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
8
Zinc, cholesterol, and heart health
Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study.
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
7
Zinc's role in cholesterol management
The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats.
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
References
Chhina GS, Chhabra A, Luthra SR, Khattar S, Singh P, et al. Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus. Cureus. 2024;16:e69180. doi:10.7759/cureus.69180
Kimura K, Suzuki F, Tsujiguchi H, Hara A, Miyagi S, et al. Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study. J Nutr Sci. 2024;13:e45. doi:10.1017/jns.2024.26
Hasani M, Monfared V, Aleebrahim-Dehkordi E, Jafari A, Agh F, et al. The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats. Curr Mol Med. 2024;24:1307. doi:10.2174/0115665240268180231113045836
Khajeh M, Hassanizadeh S, Pourteymour Fard Tabrizi F, Hassanizadeh R, Vajdi M, et al. Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis. Biol Trace Elem Res. 2024;202:4877. doi:10.1007/s12011-024-04059-x
Nani A, Bertuzzi F, Meneghini E, Mion E, Pintaudi B. Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial. J Clin Med. 2023;12. doi:10.3390/jcm12247650