Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.8
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
100 mg
†
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg
†
Top Medical Research Studies
9.5
We explored the potential benefits of idebenone, a synthetic analog of coenzyme Q10, in treating autoimmune disorders, specifically lupus, in mouse models. By administering idebenone to mice with lupus for eight weeks, we aimed to investigate its impact on disease activity and organ damage.
Our findings showed that idebenone led to a significant reduction in disease severity. Mice that received idebenone exhibited lower mortality rates and improvements in kidney function, indicated by reduced glomerular inflammation and lower levels of certain inflammatory markers. The treatment also minimized the production of proinflammatory cytokines and enhanced mitochondrial metabolism.
Besides benefiting the kidneys, idebenone diminished markers of inflammation throughout the body, which is crucial since lupus often results in systemic damage. Importantly, we noticed that idebenone improved overall metabolism in these mice without causing obvious side effects.
This research supports the idea that modulating mitochondrial function can be a promising therapeutic strategy for managing lupus, opening the door for future studies on its effectiveness in humans.
Our findings showed that idebenone led to a significant reduction in disease severity. Mice that received idebenone exhibited lower mortality rates and improvements in kidney function, indicated by reduced glomerular inflammation and lower levels of certain inflammatory markers. The treatment also minimized the production of proinflammatory cytokines and enhanced mitochondrial metabolism.
Besides benefiting the kidneys, idebenone diminished markers of inflammation throughout the body, which is crucial since lupus often results in systemic damage. Importantly, we noticed that idebenone improved overall metabolism in these mice without causing obvious side effects.
This research supports the idea that modulating mitochondrial function can be a promising therapeutic strategy for managing lupus, opening the door for future studies on its effectiveness in humans.
Read More
9
CoQ10 shows promise for autoimmune treatment
We explored the effects of coenzyme Q10 (CoQ10) as a treatment for various autoimmune disorders. Over a period from 1966 to April 2023, we reviewed 20 articles encompassing a total of 483 patients, focusing on conditions such as Fibromyalgia (FM), Rheumatoid Arthritis (RA), and Antiphospholipid Syndrome (APS).
Our findings revealed that CoQ10 supplementation resulted in notable improvements, especially for patients with RA. Specifically, these patients showed enhancements in disease activity index and reductions in inflammatory markers, including erythrocyte sedimentation rate and malondialdehyde levels. For those with APS, CoQ10 exhibited benefits such as improved endothelial function and reduced pro-inflammatory markers.
When it came to FM, most studies indicated that individuals experienced relief in symptoms related to pain, fatigue, sleep disturbances, and mood disorders. Notably, the treatment was well-received, with only minor side effects reported in a couple of cases.
Overall, CoQ10 appears to be an effective complementary treatment option for patients suffering from RA and FM. However, we encourage further research involving larger sample sizes and additional autoimmune conditions to better understand its efficacy.
Our findings revealed that CoQ10 supplementation resulted in notable improvements, especially for patients with RA. Specifically, these patients showed enhancements in disease activity index and reductions in inflammatory markers, including erythrocyte sedimentation rate and malondialdehyde levels. For those with APS, CoQ10 exhibited benefits such as improved endothelial function and reduced pro-inflammatory markers.
When it came to FM, most studies indicated that individuals experienced relief in symptoms related to pain, fatigue, sleep disturbances, and mood disorders. Notably, the treatment was well-received, with only minor side effects reported in a couple of cases.
Overall, CoQ10 appears to be an effective complementary treatment option for patients suffering from RA and FM. However, we encourage further research involving larger sample sizes and additional autoimmune conditions to better understand its efficacy.
Read More
9
CoQ10 improves rheumatoid arthritis symptoms
We conducted a randomized, double-blind, placebo-controlled trial to investigate the potential benefits of coenzyme Q10 (CoQ10) supplementation for individuals with rheumatoid arthritis (RA). Our group included 54 participants who were assigned to receive either 100 mg of CoQ10 or a placebo daily for two months. We carefully measured changes in serum matrix metalloproteinases (MMPs), as well as clinical parameters like the Disease Activity Score in 28 joints (DAS-28) before and after the treatment period.
The results were quite promising. We observed that CoQ10 significantly reduced the level of MMP-3 and improved various clinical outcomes—showing a notable drop in DAS-28 scores which indicates reduced disease activity. Furthermore, patients taking CoQ10 experienced significant reductions in swollen and tender joint counts, pain scores, and erythrocyte sedimentation rate (ESR) compared to their initial readings.
Overall, the findings suggest that CoQ10 supplementation may complement standard treatments for rheumatoid arthritis, helping to reduce inflammation and improve joint health. This new approach could offer hope for RA patients looking for additional management options.
The results were quite promising. We observed that CoQ10 significantly reduced the level of MMP-3 and improved various clinical outcomes—showing a notable drop in DAS-28 scores which indicates reduced disease activity. Furthermore, patients taking CoQ10 experienced significant reductions in swollen and tender joint counts, pain scores, and erythrocyte sedimentation rate (ESR) compared to their initial readings.
Overall, the findings suggest that CoQ10 supplementation may complement standard treatments for rheumatoid arthritis, helping to reduce inflammation and improve joint health. This new approach could offer hope for RA patients looking for additional management options.
Read More
Most Useful Reviews
9
Increased energy levels
38 people found this helpful
I truly want to enjoy life fully. Suffering from chronic fatigue, I discovered CoQ10, and within just a few days, I experienced a surge in energy. I no longer feel exhausted, and I highly recommend this to anyone with chronic fatigue!
Read More
9
Breathlessness alleviated
7 people found this helpful
I ordered this for my mother, who struggled with breathlessness. After two weeks of use, her air-supply issues have disappeared. I also ordered another for my aunt's birthday, knowing it will benefit her too.
Read More
9
Boost of energy
7 people found this helpful
I reordered this 360-capsule jar. I've been using it daily after meals alongside omega-3. While I can’t confirm its heart health benefits, it definitely boosts my energy. My grandmothers also report feeling more vigorous.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
- All Researches
9.5
We explored the potential benefits of idebenone, a synthetic analog of coenzyme Q10, in treating autoimmune disorders, specifically lupus, in mouse models. By administering idebenone to mice with lupus for eight weeks, we aimed to investigate its impact on disease activity and organ damage.
Our findings showed that idebenone led to a significant reduction in disease severity. Mice that received idebenone exhibited lower mortality rates and improvements in kidney function, indicated by reduced glomerular inflammation and lower levels of certain inflammatory markers. The treatment also minimized the production of proinflammatory cytokines and enhanced mitochondrial metabolism.
Besides benefiting the kidneys, idebenone diminished markers of inflammation throughout the body, which is crucial since lupus often results in systemic damage. Importantly, we noticed that idebenone improved overall metabolism in these mice without causing obvious side effects.
This research supports the idea that modulating mitochondrial function can be a promising therapeutic strategy for managing lupus, opening the door for future studies on its effectiveness in humans.
Our findings showed that idebenone led to a significant reduction in disease severity. Mice that received idebenone exhibited lower mortality rates and improvements in kidney function, indicated by reduced glomerular inflammation and lower levels of certain inflammatory markers. The treatment also minimized the production of proinflammatory cytokines and enhanced mitochondrial metabolism.
Besides benefiting the kidneys, idebenone diminished markers of inflammation throughout the body, which is crucial since lupus often results in systemic damage. Importantly, we noticed that idebenone improved overall metabolism in these mice without causing obvious side effects.
This research supports the idea that modulating mitochondrial function can be a promising therapeutic strategy for managing lupus, opening the door for future studies on its effectiveness in humans.
Read More
9
CoQ10 shows promise for autoimmune treatment
We explored the effects of coenzyme Q10 (CoQ10) as a treatment for various autoimmune disorders. Over a period from 1966 to April 2023, we reviewed 20 articles encompassing a total of 483 patients, focusing on conditions such as Fibromyalgia (FM), Rheumatoid Arthritis (RA), and Antiphospholipid Syndrome (APS).
Our findings revealed that CoQ10 supplementation resulted in notable improvements, especially for patients with RA. Specifically, these patients showed enhancements in disease activity index and reductions in inflammatory markers, including erythrocyte sedimentation rate and malondialdehyde levels. For those with APS, CoQ10 exhibited benefits such as improved endothelial function and reduced pro-inflammatory markers.
When it came to FM, most studies indicated that individuals experienced relief in symptoms related to pain, fatigue, sleep disturbances, and mood disorders. Notably, the treatment was well-received, with only minor side effects reported in a couple of cases.
Overall, CoQ10 appears to be an effective complementary treatment option for patients suffering from RA and FM. However, we encourage further research involving larger sample sizes and additional autoimmune conditions to better understand its efficacy.
Our findings revealed that CoQ10 supplementation resulted in notable improvements, especially for patients with RA. Specifically, these patients showed enhancements in disease activity index and reductions in inflammatory markers, including erythrocyte sedimentation rate and malondialdehyde levels. For those with APS, CoQ10 exhibited benefits such as improved endothelial function and reduced pro-inflammatory markers.
When it came to FM, most studies indicated that individuals experienced relief in symptoms related to pain, fatigue, sleep disturbances, and mood disorders. Notably, the treatment was well-received, with only minor side effects reported in a couple of cases.
Overall, CoQ10 appears to be an effective complementary treatment option for patients suffering from RA and FM. However, we encourage further research involving larger sample sizes and additional autoimmune conditions to better understand its efficacy.
Read More
9
In a comprehensive study, we explored the potential benefits of Coenzyme Q10 (CoQ10) in addressing the challenges of Multiple Sclerosis (MS), a chronic autoimmune disorder that leads to the degradation of protective myelin in the central nervous system. Using a well-established mouse model, we divided the animals into groups—some receiving a diet containing cuprizone (CPZ) to induce MS symptoms, while one group was also given CoQ10 to assess its impact on demyelination and remyelination.
Over a period of 12 weeks, the effects of CoQ10 were assessed through behavioral tests and molecular analyses. We noted improvements in the histological results for those treated with CoQ10, including increased levels of myelin basic protein and specific markers that indicate support for oligodendrocyte health. These findings suggest that CoQ10 administration can significantly promote remyelination and reduce oxidative stress and inflammation linked to CPZ exposure.
While the CPZ group did not exhibit significant differences in behavioral tests compared to controls, the positive cellular and histological outcomes demonstrated the treatment's promise. Overall, our findings could imply that CoQ10 might be beneficial in managing remyelination processes in MS, although further research in human subjects is needed to fully understand its potential.
Over a period of 12 weeks, the effects of CoQ10 were assessed through behavioral tests and molecular analyses. We noted improvements in the histological results for those treated with CoQ10, including increased levels of myelin basic protein and specific markers that indicate support for oligodendrocyte health. These findings suggest that CoQ10 administration can significantly promote remyelination and reduce oxidative stress and inflammation linked to CPZ exposure.
While the CPZ group did not exhibit significant differences in behavioral tests compared to controls, the positive cellular and histological outcomes demonstrated the treatment's promise. Overall, our findings could imply that CoQ10 might be beneficial in managing remyelination processes in MS, although further research in human subjects is needed to fully understand its potential.
Read More
9
We explored the anti-inflammatory effects of Coenzyme Q10 (CoQ10) using liposome/gold hybrid nanoparticles, referred to as LGNP-CoQ10, specifically in the context of rheumatoid arthritis. The study involved administering both CoQ10 and LGNP-CoQ10 orally to mice suffering from collagen-induced arthritis (CIA) over a period of 10 weeks.
To understand the impact, we analyzed the joint tissues for inflammation pathology and also looked closely at the immune response through various staining techniques. Our findings revealed a notable decrease in pro-inflammatory cytokines and populations of Th17 cells, which are commonly associated with autoimmune responses, in the mice treated with LGNP-CoQ10.
Additionally, when we tested human peripheral blood mononuclear cells, we observed that the IL-17 expression significantly dropped when treated with the LGNP-CoQ10 formulation. This suggests that the hybrid nanoparticle approach effectively enhances the anti-inflammatory properties of CoQ10, indicating its potential as a therapeutic option for rheumatoid arthritis.
To understand the impact, we analyzed the joint tissues for inflammation pathology and also looked closely at the immune response through various staining techniques. Our findings revealed a notable decrease in pro-inflammatory cytokines and populations of Th17 cells, which are commonly associated with autoimmune responses, in the mice treated with LGNP-CoQ10.
Additionally, when we tested human peripheral blood mononuclear cells, we observed that the IL-17 expression significantly dropped when treated with the LGNP-CoQ10 formulation. This suggests that the hybrid nanoparticle approach effectively enhances the anti-inflammatory properties of CoQ10, indicating its potential as a therapeutic option for rheumatoid arthritis.
Read More
9
CoQ10 improves rheumatoid arthritis symptoms
We conducted a randomized, double-blind, placebo-controlled trial to investigate the potential benefits of coenzyme Q10 (CoQ10) supplementation for individuals with rheumatoid arthritis (RA). Our group included 54 participants who were assigned to receive either 100 mg of CoQ10 or a placebo daily for two months. We carefully measured changes in serum matrix metalloproteinases (MMPs), as well as clinical parameters like the Disease Activity Score in 28 joints (DAS-28) before and after the treatment period.
The results were quite promising. We observed that CoQ10 significantly reduced the level of MMP-3 and improved various clinical outcomes—showing a notable drop in DAS-28 scores which indicates reduced disease activity. Furthermore, patients taking CoQ10 experienced significant reductions in swollen and tender joint counts, pain scores, and erythrocyte sedimentation rate (ESR) compared to their initial readings.
Overall, the findings suggest that CoQ10 supplementation may complement standard treatments for rheumatoid arthritis, helping to reduce inflammation and improve joint health. This new approach could offer hope for RA patients looking for additional management options.
The results were quite promising. We observed that CoQ10 significantly reduced the level of MMP-3 and improved various clinical outcomes—showing a notable drop in DAS-28 scores which indicates reduced disease activity. Furthermore, patients taking CoQ10 experienced significant reductions in swollen and tender joint counts, pain scores, and erythrocyte sedimentation rate (ESR) compared to their initial readings.
Overall, the findings suggest that CoQ10 supplementation may complement standard treatments for rheumatoid arthritis, helping to reduce inflammation and improve joint health. This new approach could offer hope for RA patients looking for additional management options.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Increased energy levels
38 people found this helpful
I truly want to enjoy life fully. Suffering from chronic fatigue, I discovered CoQ10, and within just a few days, I experienced a surge in energy. I no longer feel exhausted, and I highly recommend this to anyone with chronic fatigue!
Read More
9
Breathlessness alleviated
7 people found this helpful
I ordered this for my mother, who struggled with breathlessness. After two weeks of use, her air-supply issues have disappeared. I also ordered another for my aunt's birthday, knowing it will benefit her too.
Read More
9
Boost of energy
7 people found this helpful
I reordered this 360-capsule jar. I've been using it daily after meals alongside omega-3. While I can’t confirm its heart health benefits, it definitely boosts my energy. My grandmothers also report feeling more vigorous.
Read More
9
Seizures reduction
3 people found this helpful
I purchased CoQ10 for my mother, who suffers from high blood pressure and related seizures. Since starting it, she's seen great results and prefers it over what she used before. She feels stronger and more energised.
Read More
9
Improved breathing
3 people found this helpful
I took CoQ10 as part of a beauty supplement recommendation but noticed significant effects. It alleviated the feeling of incomplete inspiration linked to my autoimmune disorder, allowing me to breathe deeply again. A friend with heart issues experienced relief from tachycardia after trying it. I’ve ordered more for myself and my mother, and plan to keep using it.
Read More
Frequently Asked Questions
9
Increased energy levels
38 people found this helpful
I truly want to enjoy life fully. Suffering from chronic fatigue, I discovered CoQ10, and within just a few days, I experienced a surge in energy. I no longer feel exhausted, and I highly recommend this to anyone with chronic fatigue!
9
Breathlessness alleviated
7 people found this helpful
I ordered this for my mother, who struggled with breathlessness. After two weeks of use, her air-supply issues have disappeared. I also ordered another for my aunt's birthday, knowing it will benefit her too.
8
Joint pain relief
2 people found this helpful
I sought to improve my health as I age and found CoQ10. After a month of taking Dr Best Q10 with Omega supplements, I noticed significant relief from joint pain linked to my autoimmune disorder. The swelling subsided, and I could wear my wedding ring comfortably for the first time in years. My parents are also benefiting, so I'll continue taking this supplement.
7.5
Reduced inflammation
3 people found this helpful
I ordered Coenzyme Q10 for my mother, who has an autoimmune disorder affecting her blood vessels, causing bruises easily. She takes it with vitamin C, and her condition has improved. Additionally, her sensitivity to weather changes has decreased, and her blood pressure has stabilised, which demonstrates the effectiveness of CoQ10 for cardiovascular health. Research indicates that low CoQ10 levels are linked to inflammation and various diseases. Thus, she will continue using this supplement.
9
Boost of energy
7 people found this helpful
I reordered this 360-capsule jar. I've been using it daily after meals alongside omega-3. While I can’t confirm its heart health benefits, it definitely boosts my energy. My grandmothers also report feeling more vigorous.
7
We explored the impact of Coenzyme Q10 (CoQ10) supplementation on multiple sclerosis (MS), an autoimmune disorder that significantly affects the central nervous system. Our approach followed established systematic review methods, analyzing studies that looked into how CoQ10 might influence oxidative stress, inflammation, and clinical symptoms in MS patients.
Through our review of existing research, we observed that CoQ10 appears to have beneficial, dose-dependent effects, helping to reduce oxidative stress and inflammation in individuals with MS. Moreover, there are indications that it could provide relief from some clinical symptoms linked to the disease. However, we must recognize the limitations of the evidence, notably the small number of studies included in our review.
It's also important to note that definitive clinical recommendations cannot yet be made, as future studies are necessary to build a more substantial body of evidence. Thus, while CoQ10 shows promise, more research is needed to fully understand its role in managing autoimmune disorders like MS.
Through our review of existing research, we observed that CoQ10 appears to have beneficial, dose-dependent effects, helping to reduce oxidative stress and inflammation in individuals with MS. Moreover, there are indications that it could provide relief from some clinical symptoms linked to the disease. However, we must recognize the limitations of the evidence, notably the small number of studies included in our review.
It's also important to note that definitive clinical recommendations cannot yet be made, as future studies are necessary to build a more substantial body of evidence. Thus, while CoQ10 shows promise, more research is needed to fully understand its role in managing autoimmune disorders like MS.
9
CoQ10 improves rheumatoid arthritis symptoms
We conducted a randomized, double-blind, placebo-controlled trial to investigate the potential benefits of coenzyme Q10 (CoQ10) supplementation for individuals with rheumatoid arthritis (RA). Our group included 54 participants who were assigned to receive either 100 mg of CoQ10 or a placebo daily for two months. We carefully measured changes in serum matrix metalloproteinases (MMPs), as well as clinical parameters like the Disease Activity Score in 28 joints (DAS-28) before and after the treatment period.
The results were quite promising. We observed that CoQ10 significantly reduced the level of MMP-3 and improved various clinical outcomes—showing a notable drop in DAS-28 scores which indicates reduced disease activity. Furthermore, patients taking CoQ10 experienced significant reductions in swollen and tender joint counts, pain scores, and erythrocyte sedimentation rate (ESR) compared to their initial readings.
Overall, the findings suggest that CoQ10 supplementation may complement standard treatments for rheumatoid arthritis, helping to reduce inflammation and improve joint health. This new approach could offer hope for RA patients looking for additional management options.
The results were quite promising. We observed that CoQ10 significantly reduced the level of MMP-3 and improved various clinical outcomes—showing a notable drop in DAS-28 scores which indicates reduced disease activity. Furthermore, patients taking CoQ10 experienced significant reductions in swollen and tender joint counts, pain scores, and erythrocyte sedimentation rate (ESR) compared to their initial readings.
Overall, the findings suggest that CoQ10 supplementation may complement standard treatments for rheumatoid arthritis, helping to reduce inflammation and improve joint health. This new approach could offer hope for RA patients looking for additional management options.
8
We explored how coenzyme Q10, a natural compound found in our bodies, may benefit those suffering from autoimmune disorders like rheumatoid arthritis (RA). In recent years, there has been significant interest in combining coenzyme Q10 with traditional treatments known as disease-modifying anti-rheumatic drugs (DMARDs).
Through various studies and clinical trials, we observed that pairing coenzyme Q10 with DMARDs has shown promising effects. This combination might not only help reduce inflammation but also lessen some of the unwanted side effects associated with standard RA medications.
However, we must also acknowledge that the effectiveness of coenzyme Q10 can depend on factors like solubility and how well it gets absorbed by our bodies. Some studies highlighted these challenges, emphasizing the need for improved delivery methods to maximize the potential benefits of this supplement.
Overall, integrating coenzyme Q10 into RA treatment plans presents an exciting opportunity for enhancing patient care. It could lead to better outcomes, fewer side effects, and a more holistic approach to managing autoimmune disorders.
Through various studies and clinical trials, we observed that pairing coenzyme Q10 with DMARDs has shown promising effects. This combination might not only help reduce inflammation but also lessen some of the unwanted side effects associated with standard RA medications.
However, we must also acknowledge that the effectiveness of coenzyme Q10 can depend on factors like solubility and how well it gets absorbed by our bodies. Some studies highlighted these challenges, emphasizing the need for improved delivery methods to maximize the potential benefits of this supplement.
Overall, integrating coenzyme Q10 into RA treatment plans presents an exciting opportunity for enhancing patient care. It could lead to better outcomes, fewer side effects, and a more holistic approach to managing autoimmune disorders.
7
Coenzyme Q10's potential in treatment
Our systematic review examined how coenzyme Q10 might influence autoimmune disorders, an area of growing interest given the challenges faced by individuals living with these conditions. We analyzed data from multiple randomized controlled trials to determine if this nutraceutical could offer any improvements in clinical outcomes for patients.
The findings revealed that coenzyme Q10 has been tested in a few studies for its effects on biological and clinical measures related to autoimmune disorders. While some improvements were noted, particularly in aspects like fatigue and overall well-being, it’s essential to highlight that the studies were relatively small. Thus, conclusions drawn from these trials must be approached with caution.
Moreover, the research indicates a need for larger-scale studies to confirm these initial findings. It's clear that while there is some promise in the potential benefits of coenzyme Q10 for those with autoimmune disorders, more robust evidence is required to firmly establish its role in treatment regimens.
The findings revealed that coenzyme Q10 has been tested in a few studies for its effects on biological and clinical measures related to autoimmune disorders. While some improvements were noted, particularly in aspects like fatigue and overall well-being, it’s essential to highlight that the studies were relatively small. Thus, conclusions drawn from these trials must be approached with caution.
Moreover, the research indicates a need for larger-scale studies to confirm these initial findings. It's clear that while there is some promise in the potential benefits of coenzyme Q10 for those with autoimmune disorders, more robust evidence is required to firmly establish its role in treatment regimens.
References
- Salekzamani S, Pakkhesal S, Babaei M, Mirzaaghazadeh E, Mosaddeghi-Heris R, et al. Coenzyme Q10 supplementation in multiple sclerosis; A systematic review. Mult Scler Relat Disord. 2025;93:106212. 10.1016/j.msard.2024.106212
- Sun L, Xiao H, Ren Y, Xu K, Zhong X, et al. [Clinical and genetic analysis of a child with co-morbid progressive IgA nephropathy and COQ8B-associated glomerulopathy]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2024;41:1231. 10.3760/cma.j.cn511374-20240305-00144
- Poznyak AV, Orekhov NA, Churov AV, Starodubtseva IA, Beloyartsev DF, et al. Mitochondrial Dysfunction in Systemic Lupus Erythematosus: Insights and Therapeutic Potential. Diseases. 2024;12. 10.3390/diseases12090226
- Freire de Carvalho J, Skare T. Coenzyme Q10 supplementation in rheumatic diseases: A systematic review. Clin Nutr ESPEN. 2024;59:63. 10.1016/j.clnesp.2023.11.016
- Hossein Haghighi A, Ahmadi A, Carotenuto A, Askari R, Nikkhah K, et al. Effects of concurrent training and CoQ10 on neurotrophic factors and physical function in people with Multiple Sclerosis: a pilot study. Eur J Transl Myol. 2023;33. 10.4081/ejtm.2023.11253
- Abdelkader HA, Rashed LA, Assaad E, Saleh MA. Serum and tissue levels of coenzyme Q10 in pemphigus vulgaris. J Cosmet Dermatol. 2022;21:3002. 10.1111/jocd.14511
- Kucharská J, Poništ S, Vančová O, Gvozdjáková A, Uličná O, et al. Treatment with coenzyme Q10, omega-3-polyunsaturated fatty acids and their combination improved bioenergetics and levels of coenzyme Q9 and Q10 in skeletal muscle mitochondria in experimental model of arthritis. Physiol Res. 2021;70:723.
- López-Pedrera C, Villalba JM, Patiño-Trives AM, Luque-Tévar M, Barbarroja N, et al. Therapeutic Potential and Immunomodulatory Role of Coenzyme Q and Its Analogues in Systemic Autoimmune Diseases. Antioxidants (Basel). 2021;10. 10.3390/antiox10040600
- Kour G, Haq SA, Bajaj BK, Gupta PN, Ahmed Z. Phytochemical add-on therapy to DMARDs therapy in rheumatoid arthritis: In vitro and in vivo bases, clinical evidence and future trends. Pharmacol Res. 2021;169:105618. 10.1016/j.phrs.2021.105618
- Khalilian B, Madadi S, Fattahi N, Abouhamzeh B. Coenzyme Q10 enhances remyelination and regulate inflammation effects of cuprizone in corpus callosum of chronic model of multiple sclerosis. J Mol Histol. 2021;52:125. 10.1007/s10735-020-09929-x
- Jhun J, Moon J, Ryu J, Shin Y, Lee S, et al. Liposome/gold hybrid nanoparticle encoded with CoQ10 (LGNP-CoQ10) suppressed rheumatoid arthritis via STAT3/Th17 targeting. PLoS One. 2020;15:e0241080. 10.1371/journal.pone.0241080
- Marx W, Hockey M, McGuinness AJ, Lane M, Christodoulou J, et al. The effect of emerging nutraceutical interventions for clinical and biological outcomes in multiple sclerosis: A systematic review. Mult Scler Relat Disord. 2020;37:101486. 10.1016/j.msard.2019.101486
- Blanco LP, Pedersen HL, Wang X, Lightfoot YL, Seto N, et al. Improved Mitochondrial Metabolism and Reduced Inflammation Following Attenuation of Murine Lupus With Coenzyme Q10 Analog Idebenone. Arthritis Rheumatol. 2020;72:454. 10.1002/art.41128
- Nachvak SM, Alipour B, Mahdavi AM, Aghdashi MA, Abdollahzad H, et al. Effects of coenzyme Q10 supplementation on matrix metalloproteinases and DAS-28 in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial. Clin Rheumatol. 2019;38:3367. 10.1007/s10067-019-04723-x
