Riboflavin may improve symptomsTherapeutic trial in the first three Asian cases of ethylmalonic encephalopathy: response to riboflavin.
Study evaluates combined treatment impact
We observed three Korean girls suffering from ethylmalonic encephalopathy, marking the first known cases in Asia. Through treatment with riboflavin and coenzyme Q10, we noted slight improvements in their motor functions, cognitive behaviors, and notably, their chronic mucoid diarrhea.
Although the improvements were modest, the connection between these treatments and their impact on diarrhea is intriguing. It's worth mentioning that since both riboflavin and coenzyme Q10 were used in the study, we cannot definitively isolate the effects of coenzyme Q10 on diarrhea alone.
The precise cause of ethylmalonic encephalopathy is still unclear, but our findings suggest that riboflavin may offer some benefit. Overall, while we didn't see a significant breakthrough regarding diarrhea, the potential of these treatments warrants further exploration to understand their full effects.
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