Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More
9.5
Magnesium's role in brain tumor treatment
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More
Most Useful Reviews
9
Life-changing effect
106 people found this helpful
Highly recommended! At just 26, I've had sleep issues for years, often not sleeping until 3-4am. After starting DOCTOR’s magnesium pill, I felt relaxed and experienced improved sleep quality. I now sleep around 12-1am, which is a remarkable change! Despite the larger pill size, it wasn’t a concern for me. I’m grateful for including magnesium in my regimen.
Read More
9
Hypertension relief
52 people found this helpful
After a year of use, my hypertension and related palpitations have disappeared, allowing me to stop medication. Magnesium deficiency seemed to be the cause of my hypertension, and I feel much better since taking this.
Read More
9
Headache reduction
14 people found this helpful
My migraine occurrences have decreased remarkably, and I enjoy a newfound ease in my life! I've faced occasional constipation; I'm curious if this is related to magnesium intake. Overall, I'm pleased with the improvements.
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More
7
Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More
User Reviews
USERS' SCORE
Good
Based on 22 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
9
Life-changing effect
106 people found this helpful
Highly recommended! At just 26, I've had sleep issues for years, often not sleeping until 3-4am. After starting DOCTOR’s magnesium pill, I felt relaxed and experienced improved sleep quality. I now sleep around 12-1am, which is a remarkable change! Despite the larger pill size, it wasn’t a concern for me. I’m grateful for including magnesium in my regimen.
Read More
9
Hypertension relief
52 people found this helpful
After a year of use, my hypertension and related palpitations have disappeared, allowing me to stop medication. Magnesium deficiency seemed to be the cause of my hypertension, and I feel much better since taking this.
Read More
9
Headache reduction
14 people found this helpful
My migraine occurrences have decreased remarkably, and I enjoy a newfound ease in my life! I've faced occasional constipation; I'm curious if this is related to magnesium intake. Overall, I'm pleased with the improvements.
Read More
7.5
Mood improvement
14 people found this helpful
After using Doctor's Best 100% High Absorption Magnesium for over 30 days, I've noticed significant improvements in brain function, mood, and stress levels. Within two weeks, my mood improved, and my irritability decreased. This product has been very beneficial for me, and I hope this review helps others.
Read More
9
Migraine relief
3 people found this helpful
Good product for migraines. 80% of migraine sufferers are magnesium deficient, and after suffering migraines for 30 years, I've finally found a solution. I can now take two magnesium pills daily without pain! Menstrual migraines affect many women, leading to heightened headache frequency. Magnesium plays a crucial role in alleviating these symptoms by supporting nerve conduction. I've experienced a significant reduction in migraine severity since starting this supplement during times of stress, and I believe magnesium is vital for overall brain health.
A brain tumor is an abnormal growth of cells in the brain or central spinal canal. These tumors can be classified as either benign (non-cancerous) or malignant (cancerous), and they can originate from the brain tissue itself (primary brain tumors) or spread to the brain from other parts of the body (secondary or metastatic brain tumors). Symptoms may vary widely depending on the tumor's location, size, and type, but common indicators include headaches, seizures, cognitive or behavioral changes, and motor skill deficiencies. Diagnosing a brain tumor typically involves imaging tests such as MRI or CT scans, followed by a biopsy to determine the type of tumor.
Treatment for brain tumors depends on several factors, including the tumor type, size, and location, as well as the patient's overall health. Common treatment options include surgery to remove the tumor, radiation therapy, and chemotherapy. While advancements in medical technology have improved treatment outcomes significantly—enabling more precise targeting of tumors and minimizing damage to surrounding healthy brain tissue—challenges still exist. It's crucial for patients to discuss all available options with their healthcare providers to determine the best course of action tailored to their specific situation.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Based on user reviews, the time it takes to see results from magnesium supplementation can vary depending on the individual and the specific health concerns being addressed. For some users, significant improvements were noted within a matter of weeks. For instance, one user reported feeling improvements in brain function and mood after just two weeks of using Doctor's magnesium product Read Review, while another mentioned calmness and restful sleep occurring within an hour of taking the supplement Read Review.
However, for more chronic conditions like a calcified brain tumor, longer usage may yield observable results. One user indicated a slight decrease in tumor size after a year of consistent magnesium intake Read Review. This suggests that while some benefits of magnesium might be experienced relatively quickly, particularly for mood and sleep, lasting effects related to serious conditions may require sustained use over a longer period.
Based on the available scientific research, there is some evidence suggesting that magnesium may have beneficial effects in the context of brain tumors. One study examined the impact of magnesium sulfate on patients undergoing brain tumor surgery and found that it lowered significant protein levels associated with brain injury, even though it did not significantly alter overall functional outcomes [3]. This indicates that while magnesium might play a role in reducing certain injury markers, more comprehensive studies are needed to clarify its potential effectiveness in brain tumor recovery.
Additionally, another study highlights the importance of monitoring magnesium levels in cancer care. A patient with advanced breast cancer experienced neurological symptoms that improved remarkably following magnesium supplementation, suggesting that low magnesium could be a contributing factor to complications during treatment [2]. While these findings point towards the relevance of magnesium in brain tumor contexts, further research is essential to establish its definitive role and therapeutic applications.
Based on user reviews, many individuals have reported notable improvements in their symptoms after incorporating magnesium supplements into their routine. A common theme emerges around sleep quality; users frequently share that they experienced significant enhancements in their ability to fall asleep and stay asleep, with one reviewer citing a shift from sleeping at 3-4 am to a more manageable 12-1 am after just a few weeks of use Read Review. Additionally, users suffering from migraines have seen a dramatic reduction in frequency and severity, with some claiming they can now take magnesium without experiencing pain—marking a major turnaround after years of struggle Read Review.
Moreover, those dealing with stress and anxiety have reported improvements in mood and cognitive function, attributing these changes to magnesium's calming properties. For instance, one user noticed a significant reduction in irritability and an overall positive shift in mental health after starting the supplement Read Review. While positive outcomes like these are encouraging, it's important to remember that individual results can vary and some users have had limited success, feeling no benefits at all from magnesium supplementation Read Review.
Based on user reviews, several individuals who are dealing with brain tumors have reported positive experiences when combining magnesium supplements with other supplements. One user specifically noted a slight decrease in the size of a calcified benign brain tumor after a year of using magnesium as recommended by their doctor, highlighting the potential benefits of this supplement in managing their condition Read Review. Additionally, another user shared that they found magnesium glycinate to be effective not only in promoting sleep but also in aiding overall brain function, suggesting that magnesium's role in supporting cognitive health may be beneficial for those facing neurological issues Read Review.
Moreover, there are reviews indicating that combining different forms of magnesium might enhance benefits; one user reported success with magnesium glycinate for sleep enhancement, while also utilizing magnesium threonate for cognitive support, leading to significant improvements in muscle control and reduced convulsions Read Review. This suggests that users are finding value in tailored supplementation approaches, particularly in managing symptoms associated with brain health. However, experiences can vary, as some users have expressed disappointment with certain magnesium forms not yielding the expected benefits, such as sleep or cognitive function improvements Read Review.
Users report varying experiences and dosages of magnesium supplements in relation to treating conditions like brain tumors and improving neurological health. One user specifically mentioned that they have been taking magnesium as recommended by their doctor for a calcified benign brain tumor, noting that after a year of use, the tumor has slightly decreased in size (review-id: a4b8921a-28cd-4be9-8ebe-e8af0de63001). This suggests that magnesium may be beneficial in managing certain brain-related health issues.
Additionally, other reviews highlighted the positive effects of magnesium on mood, brain function, and sleep quality, reinforcing the idea that appropriate dosage is crucial for maximizing these benefits. For instance, one user observed significant improvements in brain function and mood after over 30 days of using magnesium, implying that consistent use over time can yield visible results (review-id: 75911a69-96cf-4ece-a68f-fee2737e4959). However, specific dosage recommendations for treating conditions like brain tumors are not clearly defined in the user reviews, indicating a need for further research and individualized consultation with healthcare providers.
7.5
Mood improvement
14 people found this helpful
After using Doctor's Best 100% High Absorption Magnesium for over 30 days, I've noticed significant improvements in brain function, mood, and stress levels. Within two weeks, my mood improved, and my irritability decreased. This product has been very beneficial for me, and I hope this review helps others.
7.5
Calms mind effectively
1 people found this helpful
This supplement has been impactful. I've tried other magnesium forms, but this one noticeably calms my mind within an hour. My impatience lessens, and I sleep well without stomach issues. It has improved my overall well-being significantly.
7.5
Reduces tumour size
1 people found this helpful
I'm taking this magnesium supplement as recommended by Dr. Fujikawa for my calcified benign brain tumor. After a year of use, I observed that the tumour has slightly decreased in size, prompting me to continue its use.
9
Life-changing effect
106 people found this helpful
Highly recommended! At just 26, I've had sleep issues for years, often not sleeping until 3-4am. After starting DOCTOR’s magnesium pill, I felt relaxed and experienced improved sleep quality. I now sleep around 12-1am, which is a remarkable change! Despite the larger pill size, it wasn’t a concern for me. I’m grateful for including magnesium in my regimen.
9
Migraine relief
3 people found this helpful
Good product for migraines. 80% of migraine sufferers are magnesium deficient, and after suffering migraines for 30 years, I've finally found a solution. I can now take two magnesium pills daily without pain! Menstrual migraines affect many women, leading to heightened headache frequency. Magnesium plays a crucial role in alleviating these symptoms by supporting nerve conduction. I've experienced a significant reduction in migraine severity since starting this supplement during times of stress, and I believe magnesium is vital for overall brain health.
0
Lacks desired effects
Switching from a Mag Threonate product to this one was disappointing as I didn't experience any positive effects—no improvement in sleep, brain focus, or digestion. It felt like taking a placebo.
2
Induces insomnia
Magnesium glycinate is meant to aid sleep, but it makes my brain buzz and causes insomnia, likely due to excess glutamate. I find other magnesium forms like malate more tolerable.
6
Cognitive boost
1 people found this helpful
After experimenting with various magnesium forms over nine months, I found magnesium glycinate particularly helpful for sleep enhancement. I take it roughly 1.5 hours before bed, along with magnesium threonate for cognition, which has significantly reduced muscle convulsions and improved control during activities. I hope others with ADHD see similar benefits from focusing on nutrition.
7
Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
9.5
Magnesium's role in brain tumor treatment
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
References
Nalci OB, Nadaroglu H, Genc S, Hacimuftuoglu A, Alayli A. The effects of MgS nanoparticles-Cisplatin-bio-conjugate on SH-SY5Y neuroblastoma cell line. Mol Biol Rep. 2020;47:9715. 10.1007/s11033-020-05987-2
Zappia F, Verzicco I, Simoni R, Ferrari M, Coghi P, et al. Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment. Acta Biomed. 2020;91:365. 10.23750/abm.v91i2.8685
Mirrahimi B, Mortazavi A, Nouri M, Ketabchi E, Amirjamshidi A, et al. Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial. Acta Neurochir (Wien). 2015;157:985. 10.1007/s00701-015-2376-x