5/10/2025
Last update
5/10/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.1
USERS' SCORE
Good
Based on 40 Reviews
8
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
8
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Read More
8
We aimed to understand how a 24-hour infusion of magnesium sulphate affects patients with unstable angina. In a double-blind, placebo-controlled study, 62 patients were monitored for signs of myocardial ischaemia after receiving either magnesium or a placebo.
While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
Read More
8
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Read More
Most Useful Reviews
9
Continues to work
14 people found this helpful
I take magnesium transdermally and orally. After I stopped, I began experiencing leg cramps. However, once I resumed taking magnesium, the chest pain ceased. I intend to continue its use as I find it helpful. Capsules are easier to swallow, albeit manageable. Sometimes, I feel it might be stuck in my throat, so I drink carefully.
Read More
9
Leg cramps stopped
2 people found this helpful
I take magnesium both transdermally and orally. After I stopped, I experienced cramps in my legs, but they disappeared when I started taking magnesium again. I feel it is working, so I will continue its use. Capsules are easier to manage, yet I am cautious since they occasionally feel stuck in my throat when swallowed.
Read More
9
Leg cramps resolved
2 people found this helpful
I use magnesium in both transdermal and oral forms. When I chose to stop, I got cramps in my legs. Upon starting again, the pain was alleviated. I will persist with it as it feels to be helping. The capsules are typically easy to swallow, though I sometimes feel they get stuck in my throat.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.1
- All Researches
9.5
Magnesium's unclear role in chest pain
We examined the role of magnesium in treating chest pain, particularly in a case involving a young female with Gitelman syndrome. This patient experienced recurrent chest pain alongside symptoms like tingling and numbness, prompting a thorough investigation into her condition.
Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.
While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.
While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
Read More
8
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Read More
8
We explored how potassium magnesium aspartate could offer protective benefits against chest pain linked to coronary artery disease. In a study involving 98 patients with angina and arrhythmia, participants were divided into two groups. One group received the routine treatment for heart disease along with potassium magnesium aspartate, while the other only received the standard therapy.
After a week of treatment, we examined various markers of oxidative stress and monitored cardiac rhythms. The results were promising: potassium magnesium aspartate significantly improved oxidative stress levels and reduced lipid oxidative damage in patients. Notably, there was a marked decrease in the frequency of premature heartbeats in those receiving potassium magnesium aspartate compared to the control group.
It appears that by enhancing oxidative stress status, potassium magnesium aspartate may also contribute to alleviating symptoms associated with arrhythmia, including chest pain. This suggests that oxidative stress could play a critical role in the development of arrhythmias, and addressing it might help treat related symptoms effectively.
After a week of treatment, we examined various markers of oxidative stress and monitored cardiac rhythms. The results were promising: potassium magnesium aspartate significantly improved oxidative stress levels and reduced lipid oxidative damage in patients. Notably, there was a marked decrease in the frequency of premature heartbeats in those receiving potassium magnesium aspartate compared to the control group.
It appears that by enhancing oxidative stress status, potassium magnesium aspartate may also contribute to alleviating symptoms associated with arrhythmia, including chest pain. This suggests that oxidative stress could play a critical role in the development of arrhythmias, and addressing it might help treat related symptoms effectively.
Read More
8
In a controlled study involving 53 male patients with stable coronary artery disease (CAD), we investigated the impact of oral magnesium supplementation on exercise-related heart rate and chest pain. Some participants received 15 mmol of magnesium twice daily, while others were given a placebo for six months.
Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.
By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.
By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
Read More
8
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 40 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Continues to work
14 people found this helpful
I take magnesium transdermally and orally. After I stopped, I began experiencing leg cramps. However, once I resumed taking magnesium, the chest pain ceased. I intend to continue its use as I find it helpful. Capsules are easier to swallow, albeit manageable. Sometimes, I feel it might be stuck in my throat, so I drink carefully.
Read More
9
Leg cramps stopped
2 people found this helpful
I take magnesium both transdermally and orally. After I stopped, I experienced cramps in my legs, but they disappeared when I started taking magnesium again. I feel it is working, so I will continue its use. Capsules are easier to manage, yet I am cautious since they occasionally feel stuck in my throat when swallowed.
Read More
9
Leg cramps resolved
2 people found this helpful
I use magnesium in both transdermal and oral forms. When I chose to stop, I got cramps in my legs. Upon starting again, the pain was alleviated. I will persist with it as it feels to be helping. The capsules are typically easy to swallow, though I sometimes feel they get stuck in my throat.
Read More
9
Positive effects noted
2 people found this helpful
I take magnesium in both transdermal and oral forms. After stopping intake, I developed leg cramps, which improved after I began taking magnesium again. I plan to keep using it as I believe it’s effective. Capsules are convenient, although I sometimes feel them lodged in my throat.
Read More
9
Continued usage warranted
2 people found this helpful
I utilise magnesium both transdermally and orally. When I stopped taking it, I suffered from leg cramps, but after resuming, the chest pain went away. I plan to keep using it as it seems to be working. Capsules are easier to manage, though sometimes they feel stuck in my throat, so I drink carefully.
Read More
Frequently Asked Questions
9
Continues to work
14 people found this helpful
I take magnesium transdermally and orally. After I stopped, I began experiencing leg cramps. However, once I resumed taking magnesium, the chest pain ceased. I intend to continue its use as I find it helpful. Capsules are easier to swallow, albeit manageable. Sometimes, I feel it might be stuck in my throat, so I drink carefully.
9
Effective treatment
1 people found this helpful
I take magnesium both transdermally and orally. After I stopped, I suffered from leg cramps, but upon resuming, the chest pain subsided. I plan to keep using it as it feels beneficial. While the capsules are easier to swallow, I occasionally feel as though they are stuck in my throat, so I am careful when consuming them.
9
Effective magnesium use
1 people found this helpful
I take magnesium transdermally and orally. When I stopped, I began experiencing cramps in my legs. However, resuming magnesium alleviated the pain. I will continue using it as I believe it is effective. While capsules are easier to swallow, I sometimes feel as though they are stuck in my throat, so I am cautious when taking them.
8
In a controlled study involving 53 male patients with stable coronary artery disease (CAD), we investigated the impact of oral magnesium supplementation on exercise-related heart rate and chest pain. Some participants received 15 mmol of magnesium twice daily, while others were given a placebo for six months.
Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.
By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.
By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
4
Magnesium shows limited chest pain effect
We investigated the effects of magnesium sulfate treatment on patients suffering from acute myocardial infarction (AMI) who underwent coronary reperfusion therapy. In this study, 38 patients were analyzed—19 received magnesium, while 19 were given a placebo. Although magnesium treatment significantly reduced the occurrence of arrhythmias, it did not show a marked improvement in the incidence of chest pain aggravation, with rates of 67% in the treatment group and 73% in the placebo group. Thus, while magnesium has protective qualities, it may not alleviate chest pain effectively in these cases.
8
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
4
Magnesium shows limited chest pain relief
We investigated how magnesium treatment affects chest pain in patients with variant angina. In our study involving 15 patients, we noted that while magnesium reduced exercise-induced ST segment elevation for some, it didn’t significantly correlate with magnesium deficiency levels. After placebo, all participants experienced angina attacks, but after magnesium treatment, fewer attacks were reported. Ultimately, we found that magnesium administered intravenously has limited effectiveness for this condition.
References
- Ola O, Gharacholou SM, Del-Carpio Munoz F. Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room". JAMA Intern Med. 2021;181:1393. 10.1001/jamainternmed.2021.4021
- Poudel A. An adolescent with tingling and numbness of hand: gitelman syndrome. N Am J Med Sci. 2015;7:27. 10.4103/1947-2714.150086
- Amoozgar H, Rafizadeh H, Ajami G, Borzoee M. The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy. Int Cardiovasc Res J. 2012;6:92.
- Zhi YF, Huang YS, Xu BS, Wang SR. [Clinical investigation of the protective effects of potassium magnesium aspartate against arrhythmia and its possible anti-oxidative mechanism]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007;19:662.
- Pokan R, Hofmann P, von Duvillard SP, Smekal G, Wonisch M, et al. Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients. Br J Sports Med. 2006;40:773.
- Sovová E, Skvarilová M, Bartousek J, Doupal V, Lukl J, et al. [Latent tetany in patients with a negative coronarographic finding]. Vnitr Lek. 1999;45:291.
- Guo H, Cheng J, Lee JD, Ueda T, Shan J, et al. Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004;29:299.
- Shechter M, Bairey Merz CN, Stuehlinger HG, Slany J, Pachinger O, et al. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease. Am J Cardiol. 2003;91:517.
- Ezhov AV, Pimenov LT. [Effect of adjuvant magnesium therapy on the quality of life and emotional status of elderly patients with stable angina]. Adv Gerontol. 2002;10:95.
- Teragawa H, Kato M, Yamagata T, Matsuura H, Kajiyama G. The preventive effect of magnesium on coronary spasm in patients with vasospastic angina. Chest. 2000;118:1690.
- Sueda S, Saeki H, Otani T, Mineoi K, Kondo T, et al. Limited efficacy of magnesium for the treatment of variant angina. J Cardiol. 1999;34:139.
- Shibata M, Ueshima K, Harada M, Nakamura M, Hiramori K, et al. Effect of magnesium sulfate pretreatment and significance of matrix metalloproteinase-1 and interleukin-6 levels in coronary reperfusion therapy for patients with acute myocardial infarction. Angiology. 1999;50:573.
- Redwood SR, Bashir Y, Huang J, Leatham EW, Kaski JC, et al. Effect of magnesium sulphate in patients with unstable angina. A double blind, randomized, placebo-controlled study. Eur Heart J. 1997;18:1269.
- Satake K, Lee JD, Shimizu H, Ueda T, Nakamura T. Relation between severity of magnesium deficiency and frequency of anginal attacks in men with variant angina. J Am Coll Cardiol. 1996;28:897.
- Gawaz M, Reininger A, Neumann FJ. Platelet function and platelet-leukocyte adhesion in symptomatic coronary heart disease. Effects of intravenous magnesium. Thromb Res. 1996;83:341.
- Otani H, Kawasaki H, Ninomiya H, Kido M, Kawaguchi H. [Significance of hot shot in patients with unstable angina undergoing emergency coronary artery bypass graft surgery]. Nihon Kyobu Geka Gakkai Zasshi. 1996;44:123.
- Caspi J, Rudis E, Bar I, Safadi T, Saute M. Effects of magnesium on myocardial function after coronary artery bypass grafting. Ann Thorac Surg. 1995;59:942.
- Feldstedt M, Boesgaard S, Bouchelouche P, Svenningsen A, Brooks L, et al. Magnesium substitution in acute ischaemic heart syndromes. Eur Heart J. 1991;12:1215.
- Tanabe K, Noda K, Mikawa T, Murayama M, Sugai J. Magnesium content of erythrocytes in patients with vasospastic angina. Cardiovasc Drugs Ther. 1991;5:677.
