We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
Read More
8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
Read More
9
Magnesium improves diarrhea-related symptoms
Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature.
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
Read More
Most Useful Reviews
9
No diarrhea issue
162 people found this helpful
Delivery took six days, which I found impressive. I ordered magnesium glycinate for my mother, as it's better absorbed and doesn't cause diarrhoea. She's using it to prevent arthrosis and anaemia. The size is manageable, and I appreciate the quality packaging from Doctor's Best. I plan to explore more products from this brand. The effect of magnesium is easily noticeable.
Read More
9
No diarrhoea effect
97 people found this helpful
I'm quite pleased with this magnesium. I take it for myself and my parents, and it's proving effective. It calms my parents' nerves and helps Mum with joint pain, and it doesn’t lead to diarrhoea. The tablets are sizeable, but they can be split if needed. We take two each night.
Read More
9
No diarrhoea concerns
50 people found this helpful
After taking this magnesium, I feel a gradual relaxation physically and mentally, especially helpful before bed. It alleviates muscle tension and has helped with menstrual pain. I'd recommend starting with one tablet, as I've experienced no side effects or diarrhoea.
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
Read More
9
Magnesium improves diarrhea-related symptoms
Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature.
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
Read More
9
Magnesium reduces diarrhea incidence
Dietary supplementation with potassium-magnesium sulfate modulates the antioxidant capacity, immunity, and gut microbiota in weaned piglets.
In our exploration of how potassium-magnesium sulfate (PMS) impacts diarrhea in weaned piglets, we set out to understand its effects on growth performance, immunity, and gut health. A total of 216 piglets were divided into six groups, with varying levels of PMS in their diets.
Our findings revealed some compelling results: the addition of PMS significantly reduced the diarrhea rate among the piglets. Notably, when we included 0.3% PMS in their diet, we observed improved antioxidant capacity, which plays a crucial role in maintaining overall gut health.
We also discovered that PMS supplementation positively influenced intestinal immunity by lowering certain inflammatory markers, further suggesting its beneficial role in digestive health. Additionally, the changes in gut bacteria composition indicated that magnesium may help foster a healthier gut environment.
Overall, our study sheds light on magnesium's potential role as a treatment option for reducing diarrhea in weaned piglets, emphasizing its effectiveness in fostering both immunity and gut health.
Read More
9
Impact of magnesium on diarrhea
Bioactivities of (Wall.) and Study against Cyclooxygenase Enzymes.
We conducted a study to assess the effectiveness of magnesium in treating diarrhea, particularly focusing on its role in extracts from (Wall.) leaves. To evaluate this, we utilized several tests that mimic diarrhea conditions. Our findings showed that while magnesium was mentioned in connection with the extracts, it was administered alongside other treatments. This means we're not entirely sure how much of the anti-diarrheal effect was due to magnesium itself.
In our tests, the methanol extract of (Wall.) leaves was particularly noteworthy, showing significant inhibition of diarrhea at a dose of 400 mg/kg. However, the role of magnesium in this context remains ambiguous since it wasn't given alone. In essence, while the extract worked well against diarrhea, the individual contribution of magnesium to this benefit is unclear.
Overall, we support the traditional use of (Wall.) plants in managing diarrhea and pain, but we need more focused research to isolate the effects of magnesium.
Read More
8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
Delivery took six days, which I found impressive. I ordered magnesium glycinate for my mother, as it's better absorbed and doesn't cause diarrhoea. She's using it to prevent arthrosis and anaemia. The size is manageable, and I appreciate the quality packaging from Doctor's Best. I plan to explore more products from this brand. The effect of magnesium is easily noticeable.
Read More
9
No diarrhoea effect
97 people found this helpful
I'm quite pleased with this magnesium. I take it for myself and my parents, and it's proving effective. It calms my parents' nerves and helps Mum with joint pain, and it doesn’t lead to diarrhoea. The tablets are sizeable, but they can be split if needed. We take two each night.
Read More
9
No diarrhoea concerns
50 people found this helpful
After taking this magnesium, I feel a gradual relaxation physically and mentally, especially helpful before bed. It alleviates muscle tension and has helped with menstrual pain. I'd recommend starting with one tablet, as I've experienced no side effects or diarrhoea.
Read More
9
Stress relief noted
47 people found this helpful
Magnesium is essential for relaxation. It inhibits excitement in the central nervous system and reduces sensitivity to stress. I recommend specific forms for different needs, like glycinate for anxiety and sleep. It’s crucial to find what's right for you, as some forms may cause diarrhoea.
Read More
9
Muscle stiffness alleviated
35 people found this helpful
This product is excellent for raising magnesium levels without causing diarrhoea. It has significantly helped with muscle stiffness.
Diarrhea is a condition characterized by the frequent passage of loose or watery stools, which can occur due to various factors, including infections, dietary choices, and underlying health conditions. It often results from the body's response to an irritation of the gastrointestinal tract, which can be caused by viruses, bacteria, parasites, or certain medications. While most cases tend to be short-lived and resolve on their own, diarrhea can lead to dehydration, especially in vulnerable populations such as young children and the elderly.
Managing diarrhea typically involves staying hydrated by drinking clear fluids and, when necessary, replenishing lost electrolytes. In some cases, over-the-counter medications may provide relief, although it’s essential to consult a healthcare professional for persistent or severe symptoms. A focus on bland, easy-to-digest foods can also help during recovery. Remember, if diarrhea persists for more than a couple of days or is accompanied by other concerning symptoms—like high fever, severe abdominal pain, or blood in stools—seeking medical attention is crucial.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium can have an effect on digestive health, but its role in managing diarrhea is complex. Magnesium is known to have a laxative effect, especially in higher doses or in certain forms, such as magnesium citrate or magnesium sulfate. This means that while magnesium can be beneficial for individuals suffering from constipation, it may exacerbate diarrhea for those who are already experiencing loose stools.
In some cases, magnesium may be helpful in alleviating diarrhea due to its overall importance in digestive function and maintaining electrolyte balance. However, if diarrhea is persistent or severe, it's crucial to consult a healthcare professional for proper evaluation and treatment. Overall, magnesium should not be seen as a primary treatment for diarrhea, and those experiencing digestive discomfort should consider other remedies and strategies alongside any magnesium supplementation.
Based on user reviews, the timeframe for seeing results when taking magnesium supplements for diarrhea can vary significantly. Some users reported experiencing gastrointestinal issues, including diarrhea, within hours of taking their first dose, particularly if they ingested more than the recommended dosage. For example, one user mentioned having diarrhea three hours after taking a single tablet, expressing concern about the effects of increased dosages Read Review. Another user shared a similar experience, noting that even two tablets resulted in persistent diarrhea, which led them to reduce their intake Read Review.
Conversely, several users found the magnesium supplement effective without causing diarrhea, allowing for noticeable relief when taken regularly. One user mentioned that despite taking up to 600 mg, they did not experience any diarrhea, suggesting a positive experience with the product Read Review. It's important to note that individual experiences may vary, and reactions can depend on factors like dosage and product form. If experiencing gastrointestinal upset, it is advisable to consult a healthcare professional for tailored advice.
Magnesium supplementation shows strong potential for managing diarrhea, particularly in specific contexts, according to recent studies. One significant research investigation highlighted that increasing magnesium levels can effectively inhibit chloride secretion in intestinal cells, a key factor in secretory diarrhea, including cholera. The study reported a 65% reduction in this secretory process when magnesium was present, suggesting that oral supplementation could be a straightforward and effective strategy for managing various types of diarrhea [1]. Additionally, another study related to HNF1B syndrome patients found that magnesium supplementation significantly improved diarrhea symptoms linked to low magnesium levels, further underscoring its role in gastrointestinal health [2].
Other investigations have offered mixed insights. While some studies indicate that magnesium can boost bowel movement frequency, they also found an associated increase in diarrhea occurrences, suggesting that magnesium may have dual effects that need to be carefully monitored in clinical settings [6]. Overall, the emerging evidence indicates that magnesium supplementation is not only supported by scientific research for managing diarrhea but also suggests a nuanced approach to its use, especially considering the potential for both benefits and drawbacks. This makes magnesium a promising option for those seeking relief from diarrhea.
Users report a range of improvements in symptoms when taking magnesium supplements, particularly those in the glycinate form, which is noted for its better absorption and lower likelihood of causing gastrointestinal issues. Many users found that magnesium significantly helped with muscle tension, joint pain, and even menstrual discomfort. For instance, one user shared that magnesium helped alleviate menstrual cramps and they could take two tablets without any stomach upset or diarrhoea Read Review. Additionally, another user indicated that it provided notable relaxation, aiding in both physical and mental stress relief Read Review.
Conversely, while some users experienced beneficial effects, others reported adverse reactions like diarrhoea, particularly with incorrect dosages or different forms of magnesium. For instance, a user indicated they switched to gylicinate after facing issues with citrate, resulting in an improved mood without gastrointestinal discomfort Read Review. It's clear from the reviews that while many found relief and positive changes, individual results can vary widely depending on the form and dosage of magnesium taken. Hence, users are advised to start with a lower dosage and monitor their body's response.
Users report a variety of experiences when combining magnesium supplements with other products, particularly in the context of managing diarrhea. A significant number of reviewers emphasized that magnesium glycinate, in particular, tends to be well-tolerated and does not commonly cause diarrhea. For example, one user noted that despite taking up to two tablets nightly, they experienced no digestive issues, which they found beneficial for their overall well-being Read Review. Conversely, some users reported adverse reactions, including diarrhea, when they took different forms of magnesium, such as citrate. One user mentioned they switched to glycinate after facing digestive issues with citrate and saw improvements without gastrointestinal discomfort Read Review.
Additionally, users advised starting with lower doses to mitigate potential side effects like diarrhea. Many found that consistent and careful dosing helped them avoid gastrointestinal disturbances. For instance, a user who gradually increased their intake noted positive results without experiencing diarrhea Read Review. However, there were instances where individuals experienced digestive upset regardless of their dosage, highlighting the importance of individual response to different supplements. Overall, while many found magnesium effective for various conditions without adverse effects, others reported that certain forms and dosages led to gastrointestinal problems, suggesting that personal experience plays a significant role in effectiveness Read Review.
According to recent research, magnesium supplementation could play a meaningful role in managing diarrhea, particularly in cases associated with deficiencies. A study emphasized that magnesium can significantly inhibit chloride secretion in intestinal cells, which can effectively reduce secretory diarrhea symptoms. The research indicated that administering magnesium in higher concentrations led to a remarkable 65% reduction in fluid secretion during episodes of diarrhea caused by cholera, suggesting that oral magnesium supplementation could be an effective therapeutic strategy in such contexts [1].
Moreover, another investigation highlighted that even in cases of magnesium deficiency, such as those caused by genetic factors, magnesium supplementation improved diarrhea symptoms significantly. This points to the importance of monitoring and potentially correcting magnesium levels in patients experiencing gastrointestinal issues [2]. Although the optimal dosage can vary depending on individual needs and health contexts, findings from a recent analysis showed that even higher doses, up to 1200 mg daily, generally did not lead to an increase in diarrhea incidents [3]. Therefore, while the exact optimal dose for every individual may not be clearly established, it seems that magnesium can be safely supplemented, particularly in cases showing deficiencies, to assist in diarrhea management.
0
Gastrointestinal upset
5 people found this helpful
I started with one tablet at night, but after two days I had diarrhoea three hours later. I can't imagine the effects of taking two tablets twice daily.
0
Causes diarrhoea
12 people found this helpful
I've been experiencing diarrhoea after taking just two tablets daily. The dosage seems too much for my system, as it persists despite my reduction in intake.
10
No diarrhea experience
5 people found this helpful
I have used this for years to lower blood pressure and manage migraine headaches. Even when I increase my dosage to 600 mg, I don’t experience diarrhea. The large pressed tablets are easy to swallow, and overall, this magnesium product offers great value.
10
Helps cramps
4 people found this helpful
I got this product to ease menstrual cramps, and it has helped significantly. I take two tablets without experiencing stomach upset or diarrhoea, and I'm pleased that it does not affect my stools.
9
No diarrhoea concerns
50 people found this helpful
After taking this magnesium, I feel a gradual relaxation physically and mentally, especially helpful before bed. It alleviates muscle tension and has helped with menstrual pain. I'd recommend starting with one tablet, as I've experienced no side effects or diarrhoea.
9
Better option
3 people found this helpful
I switched to Doctor's Best, as the magnesium citrate I was taking caused headaches and diarrhoea. This product doesn’t give me any issues and has improved my depression. I won’t go back to cheaper options.
9
No diarrhoea effect
97 people found this helpful
I'm quite pleased with this magnesium. I take it for myself and my parents, and it's proving effective. It calms my parents' nerves and helps Mum with joint pain, and it doesn’t lead to diarrhoea. The tablets are sizeable, but they can be split if needed. We take two each night.
9
Regular bowel movement
3 people found this helpful
I had chronic constipation despite taking prescribed magnesium. After starting this supplement, I experienced normal bowel movements. At first, I took two tablets before bed and one in the morning, eventually increasing to two each time. I was pleasantly surprised by the results, with no diarrhoea.
0
Wasted money
14 people found this helpful
I had good experiences with magnesium in the past, but this time, there was no smell and resulted in terrible diarrhoea for both me and my partner an hour after taking it.
9.5
Magnesium shows potential for diarrhea
Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells.
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
We investigated the effects of naldemedine, a medication often used to treat opioid-induced constipation, in combination with magnesium oxide (MgO) and other laxatives during hospital stays. Our study focused on how these treatments affected daily bowel movements and the occurrence of diarrhea.
Analysis of 93 inpatients who received at least four doses of naldemedine revealed that the addition of magnesium or other laxatives significantly increased the average daily defecation counts when compared to naldemedine alone.
However, we also noted that the combination treatments were associated with higher rates of diarrhea. This suggests that while magnesium might enhance bowel movement frequency, it could also lead to more diarrhea, which is an important consideration for treatment.
Therefore, we concluded that introducing naldemedine either alone or with magnesium could be beneficial, but healthcare providers should carefully monitor for signs of diarrhea and adjust treatments as needed.
4
Magnesium and diarrhea analysis
Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults.
We explored how magnesium supplementation affects diarrhea, particularly in adults. In recent research, we carefully reviewed data from intervention studies conducted between 1997 and 2022, focusing mainly on single-ingredient magnesium products. Our goal was to determine whether higher doses of magnesium cause significant gastrointestinal issues, especially diarrhea, which had previously shaped the established upper intake limit.
The findings were enlightening. Out of ten studies we analyzed, including five meta-analyses and five randomized controlled trials, seven indicated no significant difference in diarrhea incidents between those receiving magnesium and those given a placebo. It was interesting to note that even at doses as high as 1200 mg per day, participants generally did not report diarrhea.
When reviewing adverse event data reported to the FDA, we found just 40 cases of gastrointestinal issues linked to magnesium supplementation. Quite tellingly, only one-third of these involved complaints about diarrhea. This suggests that the concern regarding magnesium causing significant gastrointestinal problems may be overstated.
Overall, our evaluation indicates that adults can often consume magnesium supplements above the current upper intake level without significant adverse effects related to diarrhea. This opens up opportunities for increasing magnesium intake, which could help address inadequacies in this essential nutrient for many individuals.
References
de Souza Goncalves L, Chu T, Master R, Chhetri PD, Gao Q, et al. Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells. J Clin Invest. 2024;134. doi:10.1172/JCI171249
Wang Y, Xiao X, Lin Q, Song R, Wang X, et al. Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia. J Diabetes Investig. 2024;15:121. doi:10.1111/jdi.14084
Costello R, Rosanoff A, Nielsen F, West C. Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults. Adv Nutr. 2023;14:973. doi:10.1016/j.advnut.2023.06.008
Kamali F, Jamee M, Sayer JA, Sadeghi-Bojd S, Golchehre Z, et al. Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature. CEN Case Rep. 2023;12:413. doi:10.1007/s13730-023-00785-8
Cao S, Huang K, Wen X, Gao J, Cui B, et al. Dietary supplementation with potassium-magnesium sulfate modulates the antioxidant capacity, immunity, and gut microbiota in weaned piglets. Front Microbiol. 2022;13:961989. doi:10.3389/fmicb.2022.961989
Takemura M, Niki K, Miyaguchi S, Ueda M. Naldemedine-laxative combination: retrospective inpatient study. BMJ Support Palliat Care. 2024;13:e816. doi:10.1136/spcare-2022-003685
Sarkar KK, Mitra T, Rahman MA, Raja IM, Aktaruzzaman M, et al. Bioactivities of (Wall.) and Study against Cyclooxygenase Enzymes. Biomed Res Int. 2022;2022:1331758. doi:10.1155/2022/1331758