Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Moderately Good
Based on 119 Reviews
7.3
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%

Top Medical Research Studies

We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
We examined how various tocolytic drugs delay preterm birth, analyzing data from 122 trials involving nearly 13,700 women.

Our findings suggest that all classes of tocolytics, including magnesium sulfate, are likely effective for delaying birth up to 7 days compared to no treatment.

While these treatments showed promise, they also carried risks of side effects, such as nausea and headaches, particularly with betamimetics and calcium channel blockers. We found no definitive conclusions on their impact on neonatal outcomes, leaving room for further research.
Read More
7
Magnesium's efficacy for headaches
We explored the impact of magnesium treatment on headaches, focusing specifically on its role in preventing migraines. The evidence suggests that magnesium may be beneficial for some individuals in managing headache frequency and intensity. It is often recommended not only for migraine prevention but also for acute treatment when given intravenously.

Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.

Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
Read More

Most Useful Reviews

7.5
Back pain relieved
162 people found this helpful
The magnesium composition is excellent. I take two capsules at night, and on occasion, I add another if I feel stressed or have restless sleep. This routine has stopped my back pain and greatly reduced headaches, allowing me to feel rejuvenated. I find it indispensable for managing stress and overall health.
Read More
9
Headache relief
47 people found this helpful
I often have headaches and have taken too many painkillers without success. Switching to herbal medicine didn't help immediately. However, after taking three tablets a day, I suddenly noticed my headaches subsiding. They're not entirely gone, but I've stopped taking medication altogether. The tablets are large but tasteless and odorless, making them easy to swallow. Importantly, my sleep has improved as well. It's worth trying for anyone suffering from headaches!
Read More
9
No severe headaches now
45 people found this helpful
I have an autoimmune disease affecting my muscles and migraines. My husband suggested magnesium for his cramps. After two weeks, I've noticed a significant improvement in my neck pain and headaches, and I haven't had to take any painkillers since starting it. I feel much more relaxed and my shoulder pain has improved as well.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
  • All Researches
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
We examined the effects of magnesium treatment on individuals suffering from episodic migraine and tension-type headache, aiming to understand its potential benefits alongside other therapeutic approaches. The study involved 104 participants, who were assessed for anxiety, depression, insomnia, and fatigue before and after receiving various treatments, including magnesium.

Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.

Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Read More
9
Multimodal therapy shows promise
We explored a case involving a 36-year-old woman with endometriosis suffering from frequent headaches and debilitating pain. While traditional medications didn't work for her, she started a new treatment plan that included acupuncture and supplements like magnesium and turmeric.

After this multimodal approach, her headache frequency decreased significantly, along with improvements in her lumbopelvic pain, sleep quality, and overall focus. This case indicates that integrating various alternative therapies can provide significant relief for those with challenging symptoms.
Read More
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.

After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.

Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.

Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
Read More
We examined the idea that Meniere's disease (MD) might actually be a form of migraine rather than just a standalone inner ear issue. Interestingly, we found that while only about 12% of the general population deals with migraines, a staggering 51-60% of those with MD also experience migraine headaches regularly.

Furthermore, we learned that endolymphatic hydrops, a key feature often associated with MD, has also been spotted in people suffering from vestibular migraine. This connection hints that treating migraine might also benefit those with MD. A particularly effective approach we've seen involves changes in diet and lifestyle, along with magnesium and riboflavin supplements, and possibly preventative medication to manage migraine symptoms.

By treating the underlying migraine aspect, we observed that patients with MD can find relief and improvement. This indicates that MD might best be approached as a migraine-related condition, opening up new avenues for effective treatment strategies.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 119 Reviews
7.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Back pain relieved
162 people found this helpful
The magnesium composition is excellent. I take two capsules at night, and on occasion, I add another if I feel stressed or have restless sleep. This routine has stopped my back pain and greatly reduced headaches, allowing me to feel rejuvenated. I find it indispensable for managing stress and overall health.
Read More
9
Headache relief
47 people found this helpful
I often have headaches and have taken too many painkillers without success. Switching to herbal medicine didn't help immediately. However, after taking three tablets a day, I suddenly noticed my headaches subsiding. They're not entirely gone, but I've stopped taking medication altogether. The tablets are large but tasteless and odorless, making them easy to swallow. Importantly, my sleep has improved as well. It's worth trying for anyone suffering from headaches!
Read More
9
No severe headaches now
45 people found this helpful
I have an autoimmune disease affecting my muscles and migraines. My husband suggested magnesium for his cramps. After two weeks, I've noticed a significant improvement in my neck pain and headaches, and I haven't had to take any painkillers since starting it. I feel much more relaxed and my shoulder pain has improved as well.
Read More
9
Effective for headaches
21 people found this helpful
These work wonders for my headaches and muscle cramps. After running out and switching brands, the cramps returned. Once I resumed these after two days, they disappeared. Although the pills could be slimmer for easier swallowing, they are very effective.
Read More
9
Migraine relief
17 people found this helpful
I regularly visit a headache outpatient clinic and take medications like Depakene and Triptan. Since I began taking this high absorption magnesium before bed, I haven't had a migraine for over two weeks. It's remarkable, considering my headaches have persisted for over a decade. This product is affordable and certainly worth trying for those suffering from migraines.
Read More

Frequently Asked Questions

9
No migraines experienced
10 people found this helpful
After taking one tablet with riboflavin each morning for a month, I was surprised to have not experienced a single migraine during that time. Typically, I suffered from headaches twice a week, with severe instances inducing nausea and vomiting. This has brought me considerable relief.
9
Headache relief
47 people found this helpful
I often have headaches and have taken too many painkillers without success. Switching to herbal medicine didn't help immediately. However, after taking three tablets a day, I suddenly noticed my headaches subsiding. They're not entirely gone, but I've stopped taking medication altogether. The tablets are large but tasteless and odorless, making them easy to swallow. Importantly, my sleep has improved as well. It's worth trying for anyone suffering from headaches!
7.5
Effective headache relief
7 people found this helpful
Excellent magnesium in a digestible form. It has no side effects due to its chelated form, which is well absorbed. You should take four per day: two in each dose. I experienced the first noticeable effect after a month. I started taking magnesium due to severe hair loss, migraines once a month, increased irritability, and an unsteady heartbeat. With magnesium deficiency addressed, I feel much better overall. The only downside is the large tablets, which can be hard to swallow.
9
Migraine relief
17 people found this helpful
I regularly visit a headache outpatient clinic and take medications like Depakene and Triptan. Since I began taking this high absorption magnesium before bed, I haven't had a migraine for over two weeks. It's remarkable, considering my headaches have persisted for over a decade. This product is affordable and certainly worth trying for those suffering from migraines.
7.5
Headache relief
3 people found this helpful
This highly digestible magnesium, chelated with lysine and glycine, is what my doctor recommended for stress. It aids in reducing irritability and improving sleep while helping with headaches. Magnesium is crucial for our overall well-being, and I believe everyone should include it in their routine.
0
Persistent headaches
3 people found this helpful
I’m unsure why, but I experience headaches every time I take it. Magnesium citramate from Thorne seems better for me.
10
Migraine solution
5 people found this helpful
Excellent for headaches, particularly migraines when taken with a vitamin B6 pill. This is my go-to solution for headaches. Praise be to God!
9
Headaches disappeared
7 people found this helpful
A good, easily digestible magnesium I take with vitamin B6. I've become less irritable, and even headaches have disappeared. I recommend it!
9
Cramps and headaches
7 people found this helpful
I don't want to share this review, fearing that it'll sell out! For those suffering menstrual cramps, I wholeheartedly recommend increasing dosage to four pills daily before your period. Since I've started, I no longer need painkillers for headaches triggered by caffeine.
4
Magnesium's role in migraine evaluated
We explored how magnesium levels affect those suffering from migraines by comparing 50 migraine patients with an equal number of healthy controls. The study found that migraine patients had lower serum magnesium levels, both during attacks and between them, compared to healthy individuals.

Notably, there was an inverse relationship between magnesium levels and the frequency of migraine attacks. This suggests that magnesium could play a significant role in migraine mechanisms and may be worth investigating as a treatment option in the future.
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
7
Magnesium's efficacy for headaches
We explored the impact of magnesium treatment on headaches, focusing specifically on its role in preventing migraines. The evidence suggests that magnesium may be beneficial for some individuals in managing headache frequency and intensity. It is often recommended not only for migraine prevention but also for acute treatment when given intravenously.

Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.

Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.

After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.

Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.

Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
7
Magnesium shows potential benefits
The effectiveness of magnesium in treating headaches has garnered attention, particularly when we consider its potential role as a dietary supplement for both children and adults. In examining its impact, studies have indeed explored how magnesium may help alleviate headache symptoms.

Our review highlighted research findings that suggest magnesium may not only reduce headache frequency but also the intensity of pain experienced during episodes. Interestingly, some studies specifically noted that certain dietary supplements, including magnesium, could yield positive outcomes for individuals suffering from headaches.

It’s important to note, however, that while there are promising indications, the evaluation of magnesium's effectiveness often comes paired with other treatments. This raises questions about its isolated impact. Therefore, while there’s evidence pointing to magnesium's benefits, its exact role, particularly when not combined with other therapies, remains to be clarified.

References

  1. Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725
  2. Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
  3. Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
  4. Mirzaeva LM, Lobzina AS, Akhmedova KN, Shvartsman GI, Kula II, et al. [Therapeutic approaches to comorbid pathology in episodic migraine and tension-type headache]. Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123:52. doi:10.17116/jnevro202312309152
  5. Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
  6. Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. doi:10.1097/MOO.0000000000000908
  7. Verhaak A, Bakaysa S, Johnson A, Veronesi M, Williamson A, et al. Migraine treatment in pregnancy: A survey of comfort and treatment practices of women's healthcare providers. Headache. 2023;63:211. doi:10.1111/head.14436
  8. Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. doi:10.4103/0028-3886.359247
  9. Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, et al. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022;8:CD014978. doi:10.1002/14651858.CD014978.pub2
  10. Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
  11. Bharadwaj VN, Meyerowitz J, Zou B, Klukinov M, Yan N, et al. Impact of Magnesium on Oxytocin Receptor Function. Pharmaceutics. 2022;14. doi:10.3390/pharmaceutics14051105
  12. Martin BR. Multimodal Care for Headaches, Lumbopelvic Pain, and Dysmenorrhea in a Woman With Endometriosis: A Case Report. J Chiropr Med. 2021;20:148. doi:10.1016/j.jcm.2021.10.002
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