Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Moderately Good
Based on 115 Reviews
7.6
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
Most Useful Reviews
8
Enhanced relaxation benefits
1258 people found this helpful
I've found magnesium, particularly its connection with amino acids, incredibly beneficial. It absorbs well and supports relaxation, sound sleep, and blood pressure normalisation. I alternate my magnesium type every three months based on my needs, feeling rejuvenated with each cycle. It’s become an essential part of my health routine, aiding significantly in managing my heart health.
Read More
9
Crucial mineral
112 people found this helpful
Magnesium reduces the activity of various substances that contribute to blood clot formation. It is an essential mineral for a healthy heart and should be taken by everyone.
Read More
9
Improves sleep quality
42 people found this helpful
Magnesium helped restore my sleep and allowed me to wake without an alarm. Initially, I didn't expect much, but it vastly improved my mornings, unlike before when rising was impossible, even after long sleep. My husband didn't notice the same benefits, but I am grateful for waking early.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
8
Magnesium intake impacts heart disease risk
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Read More
8
We analyzed several clinical trials to examine how magnesium and potassium affect systolic blood pressure (SBP) in healthy individuals. Our findings showed that magnesium significantly reduced SBP, especially at lower doses (up to 360 mg/day) and longer treatment periods of over three months. Potassium also played a role but was effective at higher doses and shorter durations.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
Read More
8
We explored how the serum calcium-magnesium ratio impacts outcomes in patients with acute coronary syndrome (ACS) by analyzing data from 1,775 individuals who underwent coronary procedures over five years.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 115 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
8
Enhanced relaxation benefits
1258 people found this helpful
I've found magnesium, particularly its connection with amino acids, incredibly beneficial. It absorbs well and supports relaxation, sound sleep, and blood pressure normalisation. I alternate my magnesium type every three months based on my needs, feeling rejuvenated with each cycle. It’s become an essential part of my health routine, aiding significantly in managing my heart health.
Read More
9
Crucial mineral
112 people found this helpful
Magnesium reduces the activity of various substances that contribute to blood clot formation. It is an essential mineral for a healthy heart and should be taken by everyone.
Read More
9
Improves sleep quality
42 people found this helpful
Magnesium helped restore my sleep and allowed me to wake without an alarm. Initially, I didn't expect much, but it vastly improved my mornings, unlike before when rising was impossible, even after long sleep. My husband didn't notice the same benefits, but I am grateful for waking early.
Read More
9
Significant improvement
18 people found this helpful
It truly works! For 5 years, I suffered from atrial fibrillation and tried numerous drugs, damaging my thyroid. After being advised by a cardiologist to try magnesium alone, I bought Doctor's Best. After taking it for 3 weeks, I can state it works! For over ten days, I've maintained a sinus rhythm, even reducing my sotahexal dosage. No seizures post-family quarrel! I might have been magnesium deficient, which caused my arrhythmia.
Read More
0
Dissatisfaction with product
17 people found this helpful
I was disappointed with my latest batch of Doctors Best Magnesium, as it no longer provided the calming effect I relied on. Instead, I experienced an unpleasant stimulation, causing my heart to race, akin to excessive caffeine intake. This negative effect compelled me to seek alternatives, such as brands known for consistent quality. My previous experience with magnesium was positive, but this batch was unacceptable.
Read More
Frequently Asked Questions
9
Significant improvement
18 people found this helpful
It truly works! For 5 years, I suffered from atrial fibrillation and tried numerous drugs, damaging my thyroid. After being advised by a cardiologist to try magnesium alone, I bought Doctor's Best. After taking it for 3 weeks, I can state it works! For over ten days, I've maintained a sinus rhythm, even reducing my sotahexal dosage. No seizures post-family quarrel! I might have been magnesium deficient, which caused my arrhythmia.
9
Extrasystole relief
11 people found this helpful
My battle with extrasystole ended with magnesium supplementation. After experiencing distressing heart rhythms daily, I found relief after starting magnesium. My symptoms disappeared within weeks, showcasing its effectiveness. I now consistently take magnesium and have tailored my dosage based on how I feel, ensuring it remains a crucial part of my health regimen.
9
Hypertension relief
2 people found this helpful
This supplement has been invaluable for managing my blood pressure issues; it alleviated signs of hypertension. After just a week of use, I felt significantly better. It also helps stabilise my emotional responses to stress and improves sleep.
9
Improves sleep quality
42 people found this helpful
Magnesium helped restore my sleep and allowed me to wake without an alarm. Initially, I didn't expect much, but it vastly improved my mornings, unlike before when rising was impossible, even after long sleep. My husband didn't notice the same benefits, but I am grateful for waking early.
7.5
Calmer heart rate
5 people found this helpful
I’ve been enjoying this product and am now on my second pack. It remarkably reduces anxiety at work, making me feel calmer. Additionally, I’ve noticed improvements with my arrhythmias; I'm now more consistent with my medication schedule, thanks to how magnesium helps my heart function.
9
Palpitations reduced
3 people found this helpful
Works great for heart palpitations! I previously experienced recurring heart palpitations that my cardiologist diagnosed as preatrial contractions (PACs). Although PACs are not harmful, I disliked feeling them. My cardiologist recommended magnesium, and I have been taking 300mg daily of this brand for over a year. My palpitations have mostly ceased (though I occasionally experience one). The magnesium began working swiftly, within days. My cardiologist mentioned that I am fortunate, as it typically helps only about 20% of cases.
9
Medicinal benefits
3 people found this helpful
Worthy Mineral! I continuously take magnesium due to my heart issues. For many years, I relied on antihypertensive and antiarrhythmic medications. After just two weeks of taking 2 tablets a day of magnesium, my cardiologist recommended reducing my medication dosage; and within a week, I entirely stopped taking antiarrhythmic drugs. Alongside magnesium, I regularly take Omega and Vitamin D. Thank you, iHerb, for the chance to assist people!
9
Reduces cardiac risks
11 people found this helpful
Initially, I purchased magnesium to aid sleep. It’s paired with calcium for optimal absorption. This combination helps with insomnia, muscle relaxation, and stabilising nerves, while also reducing cardiovascular disease and type 2 diabetes risks. It proves beneficial for controlling blood pressure and relieving headaches.
0
Dissatisfaction with product
17 people found this helpful
I was disappointed with my latest batch of Doctors Best Magnesium, as it no longer provided the calming effect I relied on. Instead, I experienced an unpleasant stimulation, causing my heart to race, akin to excessive caffeine intake. This negative effect compelled me to seek alternatives, such as brands known for consistent quality. My previous experience with magnesium was positive, but this batch was unacceptable.
7.5
Heart support
12 people found this helpful
I've taken this magnesium for four months, noticing improvements: better sleep, reduced anxiety, and alleviated heart disturbances. It’s beneficial for hypertension, regulating blood pressure over time. I take two tablets daily and plan to continue.
9
Prevents arrhythmia
8 people found this helpful
I’ve been ordering magnesium from Doctor's Best for nearly 2 years now. After a cardiologist diagnosed a heart rhythm disorder post-60, I took numerous medications alongside magnesium. My arrhythmia has vanished, and my doctor suggested magnesium for prevention. Initially, I took 4 tablets for 14 days, then 2 for about a month, and now I take 1 daily without fail. No more arrhythmias, and my mood has significantly improved!
9
Quick relief
15 people found this helpful
It worked! Is it menopause or heart disease? The palpitations were terrible, but after drinking this 4-6 times a day, they stopped! I consume protein, various vitamins, and minerals, but what was missing was magnesium!
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
7
We investigated the effect of magnesium and calcium on blood sugar levels in 11,934 patients with coronary artery disease. Our findings indicated that higher serum magnesium levels and a favorable magnesium to calcium ratio were associated with lower abnormal HbA1c levels, which reflect better blood sugar management. In contrast, calcium showed no significant association with HbA1c levels. Importantly, we found no evidence that inflammation played a role in this relationship. Overall, magnesium might be beneficial for maintaining healthy blood sugar levels in those with heart disease.
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
References
- Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. doi:10.1161/JAHA.124.038870
- Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. doi:10.1093/ckj/sfae390
- Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. doi:10.6133/apjcn.202502_34(1).0010
- Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. doi:10.1038/s41598-025-85931-1
- Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. doi:10.1684/mrh.2024.0528
- Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. doi:10.1186/s12889-024-20785-2
- Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. doi:10.3390/nu16213617
- Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. doi:10.1371/journal.pone.0313352
- Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. doi:10.1038/s41598-024-74325-4
- Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. doi:10.4244/EIJ-D-24-00055
- Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. doi:10.1016/j.jjcc.2024.08.003
- Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. doi:10.1093/eurjpc/zwae251
- Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. doi:10.1684/mrh.2024.0517
- Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. doi:10.3390/ijerph21070932
- Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. doi:10.1080/00015385.2024.2379682
- Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. doi:10.1186/s12951-024-02685-0
