5/25/2025
Last update
5/25/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.1
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesiumlysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
8
We set out to understand how magnesium levels relate to the frequency of chest pain in women suffering from variant angina. By assessing the magnesium status in twelve participants, we divided them into two groups: those experiencing four or more angina attacks per week, and those with fewer.
Through a magnesium loading test, we discovered that women in the group with higher attack frequency had a significantly higher retention of magnesium. They also showed lower intracellular magnesium levels in their red blood cells. This suggests a clear deficiency in magnesium amongst those experiencing more frequent chest pain.
Our findings indicate a strong correlation: as magnesium levels in the cells decreased, the frequency of angina attacks increased. This suggests that addressing magnesium deficiency may be crucial for women dealing with variant angina and experiencing chest pain more frequently.
Through a magnesium loading test, we discovered that women in the group with higher attack frequency had a significantly higher retention of magnesium. They also showed lower intracellular magnesium levels in their red blood cells. This suggests a clear deficiency in magnesium amongst those experiencing more frequent chest pain.
Our findings indicate a strong correlation: as magnesium levels in the cells decreased, the frequency of angina attacks increased. This suggests that addressing magnesium deficiency may be crucial for women dealing with variant angina and experiencing chest pain more frequently.
Read More
8
We embarked on a study to understand if magnesium plays a significant role in reducing angina symptoms and improving recovery during coronary artery bypass grafting (CABG) procedures. Our investigation involved forty patients with serious coronary artery disease, who were split into two groups: one received the standard cold blood cardioplegia, while the other group was treated with a modified version enriched with potassium-magnesium aspartate.
Throughout the study, we measured important clinical outcomes, including levels of cardiac troponin I—a marker that indicates heart injury—as well as hemodynamic indexes during and post-surgery. Our findings revealed that the enriched cardioplegia solution helped reduce reperfusion injury, which is a common complication in heart surgery. While the study specifically points to benefits regarding heart recovery, it indirectly connects to magnesium's potential impact on angina.
Overall, our work highlights the importance of magnesium in cardiac procedures and suggests that enhancing cardioplegia with this mineral can lead to better outcomes for patients undergoing heart surgery. However, while it may not directly assess magnesium's effects on angina in a broad sense, it opens the door to further exploration in this area.
Throughout the study, we measured important clinical outcomes, including levels of cardiac troponin I—a marker that indicates heart injury—as well as hemodynamic indexes during and post-surgery. Our findings revealed that the enriched cardioplegia solution helped reduce reperfusion injury, which is a common complication in heart surgery. While the study specifically points to benefits regarding heart recovery, it indirectly connects to magnesium's potential impact on angina.
Overall, our work highlights the importance of magnesium in cardiac procedures and suggests that enhancing cardioplegia with this mineral can lead to better outcomes for patients undergoing heart surgery. However, while it may not directly assess magnesium's effects on angina in a broad sense, it opens the door to further exploration in this area.
Read More
We examined the effectiveness of a magnesium-based scaffold designed to deliver sirolimus, a drug that helps prevent blood vessel blockages, in patients experiencing angina due to coronary lesions. Over the course of three years, we followed 123 participants enrolled in an international, multicenter study, observing their progress after receiving this treatment.
Remarkably, at the end of the study, a high percentage—91.1%—of patients reported being free from angina symptoms. While the scaffold aimed to improve blood vessel health, we recorded a target lesion failure rate of 6.8%, which is relatively low and included a few serious events like heart attacks and deaths. Notably, no instances of scaffold thrombosis occurred, indicating the treatment was quite safe.
We also did a deeper dive with a smaller group of patients—25 individuals who voluntarily participated in angiographic assessments at 6, 12, and 36 months post-treatment. In these patients, we noted a slight increase in late lumen loss and diameter stenosis, but the increases were not substantial, suggesting that the scaffold maintained its effectiveness even beyond the time it was expected to be absorbed.
Overall, our findings indicate that while the magnesium scaffold shows promise in managing angina, especially in terms of safety, further studies may be needed to fully understand and confirm its benefits over the long term.
Remarkably, at the end of the study, a high percentage—91.1%—of patients reported being free from angina symptoms. While the scaffold aimed to improve blood vessel health, we recorded a target lesion failure rate of 6.8%, which is relatively low and included a few serious events like heart attacks and deaths. Notably, no instances of scaffold thrombosis occurred, indicating the treatment was quite safe.
We also did a deeper dive with a smaller group of patients—25 individuals who voluntarily participated in angiographic assessments at 6, 12, and 36 months post-treatment. In these patients, we noted a slight increase in late lumen loss and diameter stenosis, but the increases were not substantial, suggesting that the scaffold maintained its effectiveness even beyond the time it was expected to be absorbed.
Overall, our findings indicate that while the magnesium scaffold shows promise in managing angina, especially in terms of safety, further studies may be needed to fully understand and confirm its benefits over the long term.
Read More
Most Useful Reviews
7.5
Effective pain relief
55 people found this helpful
I have tried various remedies for my constitution and my mother’s panic disorder, but magnesium has had an immediate effect. My body has been getting weaker due to my job, and I often woke up at night with pain. After taking magnesium, I am now completely pain-free. I have also managed to deal with my vasospastic angina attacks, which I’ve been controlling with nitroglycerin for years. This has been a dramatic bonus for me. I can feel how effective it is for my nerves and muscles. I’m feeling much better now, and I hope it will benefit my mother’s mental health as well.
Read More
7.5
Angina symptom relief
I periodically take magnesium supplements, which help reduce the symptoms of angina pectoris. The chelated form of magnesium offered by this manufacturer is easily absorbed by the body and comes in a convenient dosage.
Read More
6
Relaxation benefits
28 people found this helpful
Magnesium is well-known for relaxing muscles post-exercise and soothing nerves by slowing down nerve impulses, making it ideal for night-time use. It increases serotonin levels, improving mood and reducing stress while also boosting melatonin for better sleep. Additionally, magnesium reduces adrenaline and is crucial for muscle relaxation and pain reduction. It enhances oxygen flow to the heart, alleviating angina pectoris and arrhythmias. Moreover, magnesium is effective in managing symptoms of PMS and managing heart issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
- All Researches
We examined the effectiveness of a magnesium-based scaffold designed to deliver sirolimus, a drug that helps prevent blood vessel blockages, in patients experiencing angina due to coronary lesions. Over the course of three years, we followed 123 participants enrolled in an international, multicenter study, observing their progress after receiving this treatment.
Remarkably, at the end of the study, a high percentage—91.1%—of patients reported being free from angina symptoms. While the scaffold aimed to improve blood vessel health, we recorded a target lesion failure rate of 6.8%, which is relatively low and included a few serious events like heart attacks and deaths. Notably, no instances of scaffold thrombosis occurred, indicating the treatment was quite safe.
We also did a deeper dive with a smaller group of patients—25 individuals who voluntarily participated in angiographic assessments at 6, 12, and 36 months post-treatment. In these patients, we noted a slight increase in late lumen loss and diameter stenosis, but the increases were not substantial, suggesting that the scaffold maintained its effectiveness even beyond the time it was expected to be absorbed.
Overall, our findings indicate that while the magnesium scaffold shows promise in managing angina, especially in terms of safety, further studies may be needed to fully understand and confirm its benefits over the long term.
Remarkably, at the end of the study, a high percentage—91.1%—of patients reported being free from angina symptoms. While the scaffold aimed to improve blood vessel health, we recorded a target lesion failure rate of 6.8%, which is relatively low and included a few serious events like heart attacks and deaths. Notably, no instances of scaffold thrombosis occurred, indicating the treatment was quite safe.
We also did a deeper dive with a smaller group of patients—25 individuals who voluntarily participated in angiographic assessments at 6, 12, and 36 months post-treatment. In these patients, we noted a slight increase in late lumen loss and diameter stenosis, but the increases were not substantial, suggesting that the scaffold maintained its effectiveness even beyond the time it was expected to be absorbed.
Overall, our findings indicate that while the magnesium scaffold shows promise in managing angina, especially in terms of safety, further studies may be needed to fully understand and confirm its benefits over the long term.
Read More
8
We investigated the effects of potassium magnesium aspartate on patients suffering from angina and arrhythmia related to coronary artery disease. Conducted with a single-blind approach, our study included 98 participants who were divided into two groups. The experimental group received the standard treatment plus potassium magnesium aspartate, while the control group only received standard therapy.
After a week of treatment, we found notable improvements in those taking potassium magnesium aspartate. Specifically, there was a significant enhancement in their oxidative stress status, which is crucial for heart health, along with a reduction in lipid oxidative damage. Additionally, frequent premature heartbeats, which can be troubling for patients, were also decreased.
These findings suggest that potassium magnesium aspartate isn’t just a supplement but may play a meaningful role in managing angina by alleviating some core symptoms. This highlights an interesting link between oxidative stress and heart rhythm issues. Although we can't specifically isolate the impact of magnesium alone from this study, it does hint at its promising role in promoting heart health alongside conventional treatments.
After a week of treatment, we found notable improvements in those taking potassium magnesium aspartate. Specifically, there was a significant enhancement in their oxidative stress status, which is crucial for heart health, along with a reduction in lipid oxidative damage. Additionally, frequent premature heartbeats, which can be troubling for patients, were also decreased.
These findings suggest that potassium magnesium aspartate isn’t just a supplement but may play a meaningful role in managing angina by alleviating some core symptoms. This highlights an interesting link between oxidative stress and heart rhythm issues. Although we can't specifically isolate the impact of magnesium alone from this study, it does hint at its promising role in promoting heart health alongside conventional treatments.
Read More
8
We embarked on a study to understand if magnesium plays a significant role in reducing angina symptoms and improving recovery during coronary artery bypass grafting (CABG) procedures. Our investigation involved forty patients with serious coronary artery disease, who were split into two groups: one received the standard cold blood cardioplegia, while the other group was treated with a modified version enriched with potassium-magnesium aspartate.
Throughout the study, we measured important clinical outcomes, including levels of cardiac troponin I—a marker that indicates heart injury—as well as hemodynamic indexes during and post-surgery. Our findings revealed that the enriched cardioplegia solution helped reduce reperfusion injury, which is a common complication in heart surgery. While the study specifically points to benefits regarding heart recovery, it indirectly connects to magnesium's potential impact on angina.
Overall, our work highlights the importance of magnesium in cardiac procedures and suggests that enhancing cardioplegia with this mineral can lead to better outcomes for patients undergoing heart surgery. However, while it may not directly assess magnesium's effects on angina in a broad sense, it opens the door to further exploration in this area.
Throughout the study, we measured important clinical outcomes, including levels of cardiac troponin I—a marker that indicates heart injury—as well as hemodynamic indexes during and post-surgery. Our findings revealed that the enriched cardioplegia solution helped reduce reperfusion injury, which is a common complication in heart surgery. While the study specifically points to benefits regarding heart recovery, it indirectly connects to magnesium's potential impact on angina.
Overall, our work highlights the importance of magnesium in cardiac procedures and suggests that enhancing cardioplegia with this mineral can lead to better outcomes for patients undergoing heart surgery. However, while it may not directly assess magnesium's effects on angina in a broad sense, it opens the door to further exploration in this area.
Read More
8
We set out to understand how magnesium levels relate to the frequency of chest pain in women suffering from variant angina. By assessing the magnesium status in twelve participants, we divided them into two groups: those experiencing four or more angina attacks per week, and those with fewer.
Through a magnesium loading test, we discovered that women in the group with higher attack frequency had a significantly higher retention of magnesium. They also showed lower intracellular magnesium levels in their red blood cells. This suggests a clear deficiency in magnesium amongst those experiencing more frequent chest pain.
Our findings indicate a strong correlation: as magnesium levels in the cells decreased, the frequency of angina attacks increased. This suggests that addressing magnesium deficiency may be crucial for women dealing with variant angina and experiencing chest pain more frequently.
Through a magnesium loading test, we discovered that women in the group with higher attack frequency had a significantly higher retention of magnesium. They also showed lower intracellular magnesium levels in their red blood cells. This suggests a clear deficiency in magnesium amongst those experiencing more frequent chest pain.
Our findings indicate a strong correlation: as magnesium levels in the cells decreased, the frequency of angina attacks increased. This suggests that addressing magnesium deficiency may be crucial for women dealing with variant angina and experiencing chest pain more frequently.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Effective pain relief
55 people found this helpful
I have tried various remedies for my constitution and my mother’s panic disorder, but magnesium has had an immediate effect. My body has been getting weaker due to my job, and I often woke up at night with pain. After taking magnesium, I am now completely pain-free. I have also managed to deal with my vasospastic angina attacks, which I’ve been controlling with nitroglycerin for years. This has been a dramatic bonus for me. I can feel how effective it is for my nerves and muscles. I’m feeling much better now, and I hope it will benefit my mother’s mental health as well.
Read More
7.5
Angina symptom relief
I periodically take magnesium supplements, which help reduce the symptoms of angina pectoris. The chelated form of magnesium offered by this manufacturer is easily absorbed by the body and comes in a convenient dosage.
Read More
6
Relaxation benefits
28 people found this helpful
Magnesium is well-known for relaxing muscles post-exercise and soothing nerves by slowing down nerve impulses, making it ideal for night-time use. It increases serotonin levels, improving mood and reducing stress while also boosting melatonin for better sleep. Additionally, magnesium reduces adrenaline and is crucial for muscle relaxation and pain reduction. It enhances oxygen flow to the heart, alleviating angina pectoris and arrhythmias. Moreover, magnesium is effective in managing symptoms of PMS and managing heart issues.
Read More
9
Essential for health
Magnesium is vital for our health, participating in around 300 regulatory and metabolic processes. It does not occur naturally in the body and must be obtained from diet and water. Magnesium is essential for digestion, as it activates enzymes for protein breakdown and nutrient absorption. It enhances calcium absorption for strong bones and is crucial in synthesising immune cells and neurotransmitters. It also helps regulate blood pressure and has a cardioprotective impact, protecting against conditions like angina pectoris and atherosclerosis, especially important for older women.
Read More
Frequently Asked Questions
7.5
Effective pain relief
55 people found this helpful
I have tried various remedies for my constitution and my mother’s panic disorder, but magnesium has had an immediate effect. My body has been getting weaker due to my job, and I often woke up at night with pain. After taking magnesium, I am now completely pain-free. I have also managed to deal with my vasospastic angina attacks, which I’ve been controlling with nitroglycerin for years. This has been a dramatic bonus for me. I can feel how effective it is for my nerves and muscles. I’m feeling much better now, and I hope it will benefit my mother’s mental health as well.
7.5
Angina symptom relief
I periodically take magnesium supplements, which help reduce the symptoms of angina pectoris. The chelated form of magnesium offered by this manufacturer is easily absorbed by the body and comes in a convenient dosage.
6
Relaxation benefits
28 people found this helpful
Magnesium is well-known for relaxing muscles post-exercise and soothing nerves by slowing down nerve impulses, making it ideal for night-time use. It increases serotonin levels, improving mood and reducing stress while also boosting melatonin for better sleep. Additionally, magnesium reduces adrenaline and is crucial for muscle relaxation and pain reduction. It enhances oxygen flow to the heart, alleviating angina pectoris and arrhythmias. Moreover, magnesium is effective in managing symptoms of PMS and managing heart issues.
9
Essential for health
Magnesium is vital for our health, participating in around 300 regulatory and metabolic processes. It does not occur naturally in the body and must be obtained from diet and water. Magnesium is essential for digestion, as it activates enzymes for protein breakdown and nutrient absorption. It enhances calcium absorption for strong bones and is crucial in synthesising immune cells and neurotransmitters. It also helps regulate blood pressure and has a cardioprotective impact, protecting against conditions like angina pectoris and atherosclerosis, especially important for older women.
We examined the effectiveness of a magnesium-based scaffold designed to deliver sirolimus, a drug that helps prevent blood vessel blockages, in patients experiencing angina due to coronary lesions. Over the course of three years, we followed 123 participants enrolled in an international, multicenter study, observing their progress after receiving this treatment.
Remarkably, at the end of the study, a high percentage—91.1%—of patients reported being free from angina symptoms. While the scaffold aimed to improve blood vessel health, we recorded a target lesion failure rate of 6.8%, which is relatively low and included a few serious events like heart attacks and deaths. Notably, no instances of scaffold thrombosis occurred, indicating the treatment was quite safe.
We also did a deeper dive with a smaller group of patients—25 individuals who voluntarily participated in angiographic assessments at 6, 12, and 36 months post-treatment. In these patients, we noted a slight increase in late lumen loss and diameter stenosis, but the increases were not substantial, suggesting that the scaffold maintained its effectiveness even beyond the time it was expected to be absorbed.
Overall, our findings indicate that while the magnesium scaffold shows promise in managing angina, especially in terms of safety, further studies may be needed to fully understand and confirm its benefits over the long term.
Remarkably, at the end of the study, a high percentage—91.1%—of patients reported being free from angina symptoms. While the scaffold aimed to improve blood vessel health, we recorded a target lesion failure rate of 6.8%, which is relatively low and included a few serious events like heart attacks and deaths. Notably, no instances of scaffold thrombosis occurred, indicating the treatment was quite safe.
We also did a deeper dive with a smaller group of patients—25 individuals who voluntarily participated in angiographic assessments at 6, 12, and 36 months post-treatment. In these patients, we noted a slight increase in late lumen loss and diameter stenosis, but the increases were not substantial, suggesting that the scaffold maintained its effectiveness even beyond the time it was expected to be absorbed.
Overall, our findings indicate that while the magnesium scaffold shows promise in managing angina, especially in terms of safety, further studies may be needed to fully understand and confirm its benefits over the long term.
8
We investigated the effects of potassium magnesium aspartate on patients suffering from angina and arrhythmia related to coronary artery disease. Conducted with a single-blind approach, our study included 98 participants who were divided into two groups. The experimental group received the standard treatment plus potassium magnesium aspartate, while the control group only received standard therapy.
After a week of treatment, we found notable improvements in those taking potassium magnesium aspartate. Specifically, there was a significant enhancement in their oxidative stress status, which is crucial for heart health, along with a reduction in lipid oxidative damage. Additionally, frequent premature heartbeats, which can be troubling for patients, were also decreased.
These findings suggest that potassium magnesium aspartate isn’t just a supplement but may play a meaningful role in managing angina by alleviating some core symptoms. This highlights an interesting link between oxidative stress and heart rhythm issues. Although we can't specifically isolate the impact of magnesium alone from this study, it does hint at its promising role in promoting heart health alongside conventional treatments.
After a week of treatment, we found notable improvements in those taking potassium magnesium aspartate. Specifically, there was a significant enhancement in their oxidative stress status, which is crucial for heart health, along with a reduction in lipid oxidative damage. Additionally, frequent premature heartbeats, which can be troubling for patients, were also decreased.
These findings suggest that potassium magnesium aspartate isn’t just a supplement but may play a meaningful role in managing angina by alleviating some core symptoms. This highlights an interesting link between oxidative stress and heart rhythm issues. Although we can't specifically isolate the impact of magnesium alone from this study, it does hint at its promising role in promoting heart health alongside conventional treatments.
8
We set out to understand how magnesium levels relate to the frequency of chest pain in women suffering from variant angina. By assessing the magnesium status in twelve participants, we divided them into two groups: those experiencing four or more angina attacks per week, and those with fewer.
Through a magnesium loading test, we discovered that women in the group with higher attack frequency had a significantly higher retention of magnesium. They also showed lower intracellular magnesium levels in their red blood cells. This suggests a clear deficiency in magnesium amongst those experiencing more frequent chest pain.
Our findings indicate a strong correlation: as magnesium levels in the cells decreased, the frequency of angina attacks increased. This suggests that addressing magnesium deficiency may be crucial for women dealing with variant angina and experiencing chest pain more frequently.
Through a magnesium loading test, we discovered that women in the group with higher attack frequency had a significantly higher retention of magnesium. They also showed lower intracellular magnesium levels in their red blood cells. This suggests a clear deficiency in magnesium amongst those experiencing more frequent chest pain.
Our findings indicate a strong correlation: as magnesium levels in the cells decreased, the frequency of angina attacks increased. This suggests that addressing magnesium deficiency may be crucial for women dealing with variant angina and experiencing chest pain more frequently.
References
- Haude M, Ince H, Toelg R, Lemos PA, von Birgelen C, et al. Safety and performance of the second-generation drug-eluting absorbable metal scaffold (DREAMS 2G) in patients with de novo coronary lesions: three-year clinical results and angiographic findings of the BIOSOLVE-II first-in-man trial. EuroIntervention. 2020;15:e1375. 10.4244/EIJ-D-18-01000
- Zhi YF, Huang YS, Xu BS, Wang SR. [Clinical investigation of the protective effects of potassium magnesium aspartate against arrhythmia and its possible anti-oxidative mechanism]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007;19:662.
- Ji B, Liu J, Liu M, Feng Z, Wang G, et al. Effect of cold blood cardioplegia enriched with potassium-magnesium aspartate during coronary artery bypass grafting. J Cardiovasc Surg (Torino). 2006;47:671.
- Guo H, Cheng J, Lee JD, Ueda T, Shan J, et al. Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004;29:299.
