Medical Researches
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Based on 16 Researches
Magnesium may reduce postoperative AFPerioperative systemic magnesium sulfate minimizes the incidence of atrial fibrillation after thoracotomy for lung resection: a prospective observational study.
Significant findings in AF reduction.
We explored the impact of magnesium sulfate (MgS) on the occurrence of postoperative atrial fibrillation (POAF) in patients undergoing lung surgery via thoracotomy. In a prospective observational study involving 100 patients, we looked at how adding MgS to standard anesthetic management affected the rates of AF after surgery. MgS was given during anesthesia induction and through an infusion over 24 hours to assess its potential benefits.
While we found no significant impact on the first three days after surgery, by day seven, patients who received MgS showed a marked reduction in POAF compared to those who did not receive it. Specifically, the rates were 4% for the MgS group compared to 26% for the control group. Notably, in patients who were not on long-term beta-blockers, the benefits were even clearer, with only 14% experiencing AF compared to 80% in the control group.
Overall, our findings suggest that using magnesium sulfate may be a valuable strategy for lowering the risk of POAF, particularly for patients not already taking beta-blockers. This treatment approach could lead to smoother recoveries, shorter hospital stays, and potentially lower healthcare costs.
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Magnesium's uncertain impact on AFExternal electrical and pharmacological cardioversion for atrial fibrillation, atrial flutter or atrial tachycardias: a network meta-analysis.
Score indicates limited significance
We investigated the role of magnesium among various treatments for atrial fibrillation (AF) in a comprehensive study reviewing multiple clinical trials. The analysis highlighted the effectiveness of both electrical and pharmacological cardioversion methods.
Magnesium was included in this analysis alongside other treatments like ibutilide and propafenone. However, the evidence for magnesium's specific impact on maintaining sinus rhythm was deemed low-certainty and not entirely definitive. We observed that while magnesium may show some promise, its effects were not as clearly established compared to the more robust outcomes seen with other medications.
Despite these findings, our study emphasizes the significance of patient profiles and treatment options available for managing AF. Although magnesium treatment is part of the conversation on atrial fibrillation management, its distinct benefits remain somewhat unclear when compared to other cardioversion methods.
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Magnesium's impact on AFImpact of Dysmagnesemia on Atrial Fibrillation in Maintenance Hemodialysis Patients: A Nationwide Study.
Moderate relevance to AF treatment.
We conducted a nationwide study focusing on how serum magnesium (sMg) levels are linked to atrial fibrillation (AF) in patients undergoing hemodialysis. By analyzing data from 165,926 patients across 2,549 dialysis facilities in Japan, we aimed to assess if variations in magnesium levels truly influenced the occurrence of AF.
Our findings revealed that lower sMg levels could lead to a higher risk of AF. Specifically, patients with sMg levels less than 2.5 mg/dL showed increased odds of AF compared to those within the optimal range. Interestingly, those with sMg levels above this range had fewer cases of AF. This suggests that maintaining appropriate magnesium levels could be essential for heart rhythm stability.
However, we noted that while dysmagnesemia appears to contribute to AF in this population, there is still a need for further research. Longitudinal studies are necessary to truly determine if correcting magnesium levels can reduce AF incidence effectively. Ultimately, the connection between magnesium and atrial fibrillation is a complex one, and this study adds valuable insights to a growing body of evidence.
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Magnesium aids AF cardioversionGender Differences With Ibutilide Effectiveness and Safety in Cardioversion of Atrial Fibrillation.
Study links magnesium with effectiveness
We explored the effects of magnesium treatment in patients with atrial fibrillation (AF) undergoing cardioversion with ibutilide. In our study, patients were carefully monitored; those with low magnesium levels received magnesium sulfate before ibutilide was administered.
The results showed that magnesium pretreatment improved patients' chances of converting back to a normal heart rhythm. Specifically, those who received magnesium saw a 70% success rate in returning to normal sinus rhythm (NSR).
We also noticed a significant gender difference in conversion rates—female patients converted to NSR at an impressive rate of 88%, compared to just 68% for males. This finding was interesting and may suggest that factors beyond magnesium alone contribute to treatment success in AF.
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Magnesium aids atrial fibrillation controlEfficacy of intravenous magnesium for the management of non-post operative atrial fibrillation with rapid ventricular response: A systematic review and meta-analysis.
Moderately relevant study findings
We evaluated the impact of intravenous magnesium (IV Mg) on patients experiencing atrial fibrillation (AF) with a rapid heartbeat. Our study involved a systematic review and meta-analysis of randomized controlled trials, comparing the effects of IV Mg to a placebo while patients received standard care.
Our analysis included nine trials with over a thousand patients. Remarkably, we found that IV Mg not only helped achieve better control over heart rate but also improved the chances of reverting to a normal rhythm. Specifically, it increased rate control by 87% and rhythm control by 45%, making it a promising addition to existing treatments.
We also noted that patients tolerated IV Mg well, and while side effects weren't reported in detail, there was no significant difference between groups regarding their occurrence. This suggests that magnesium could be a beneficial adjunct therapy for managing AF, especially for those who are not post-operative.
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