We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
Read More
8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
Read More
9
Magnesium improves diarrhea-related symptoms
Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature.
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
Read More
Most Useful Reviews
9
No diarrhea issue
162 people found this helpful
Delivery took six days, which I found impressive. I ordered magnesium glycinate for my mother, as it's better absorbed and doesn't cause diarrhoea. She's using it to prevent arthrosis and anaemia. The size is manageable, and I appreciate the quality packaging from Doctor's Best. I plan to explore more products from this brand. The effect of magnesium is easily noticeable.
Read More
9
No side effects
91 people found this helpful
My diet lacked magnesium, so I opted for Doctor's Best High Absorption Magnesium Glycinate. It’s easily absorbed, unlikely to cause diarrhoea, and has improved my sleep and overall wellbeing. I highly recommend it.
Read More
9
No diarrhoea concerns
50 people found this helpful
After taking this magnesium, I feel a gradual relaxation physically and mentally, especially helpful before bed. It alleviates muscle tension and has helped with menstrual pain. I'd recommend starting with one tablet, as I've experienced no side effects or diarrhoea.
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
Read More
9
Magnesium improves diarrhea-related symptoms
Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature.
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
Read More
9
Magnesium reduces diarrhea incidence
Dietary supplementation with potassium-magnesium sulfate modulates the antioxidant capacity, immunity, and gut microbiota in weaned piglets.
In our exploration of how potassium-magnesium sulfate (PMS) impacts diarrhea in weaned piglets, we set out to understand its effects on growth performance, immunity, and gut health. A total of 216 piglets were divided into six groups, with varying levels of PMS in their diets.
Our findings revealed some compelling results: the addition of PMS significantly reduced the diarrhea rate among the piglets. Notably, when we included 0.3% PMS in their diet, we observed improved antioxidant capacity, which plays a crucial role in maintaining overall gut health.
We also discovered that PMS supplementation positively influenced intestinal immunity by lowering certain inflammatory markers, further suggesting its beneficial role in digestive health. Additionally, the changes in gut bacteria composition indicated that magnesium may help foster a healthier gut environment.
Overall, our study sheds light on magnesium's potential role as a treatment option for reducing diarrhea in weaned piglets, emphasizing its effectiveness in fostering both immunity and gut health.
Read More
9
Impact of magnesium on diarrhea
Bioactivities of (Wall.) and Study against Cyclooxygenase Enzymes.
We conducted a study to assess the effectiveness of magnesium in treating diarrhea, particularly focusing on its role in extracts from (Wall.) leaves. To evaluate this, we utilized several tests that mimic diarrhea conditions. Our findings showed that while magnesium was mentioned in connection with the extracts, it was administered alongside other treatments. This means we're not entirely sure how much of the anti-diarrheal effect was due to magnesium itself.
In our tests, the methanol extract of (Wall.) leaves was particularly noteworthy, showing significant inhibition of diarrhea at a dose of 400 mg/kg. However, the role of magnesium in this context remains ambiguous since it wasn't given alone. In essence, while the extract worked well against diarrhea, the individual contribution of magnesium to this benefit is unclear.
Overall, we support the traditional use of (Wall.) plants in managing diarrhea and pain, but we need more focused research to isolate the effects of magnesium.
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8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
Delivery took six days, which I found impressive. I ordered magnesium glycinate for my mother, as it's better absorbed and doesn't cause diarrhoea. She's using it to prevent arthrosis and anaemia. The size is manageable, and I appreciate the quality packaging from Doctor's Best. I plan to explore more products from this brand. The effect of magnesium is easily noticeable.
Read More
9
No side effects
91 people found this helpful
My diet lacked magnesium, so I opted for Doctor's Best High Absorption Magnesium Glycinate. It’s easily absorbed, unlikely to cause diarrhoea, and has improved my sleep and overall wellbeing. I highly recommend it.
Read More
9
No diarrhoea concerns
50 people found this helpful
After taking this magnesium, I feel a gradual relaxation physically and mentally, especially helpful before bed. It alleviates muscle tension and has helped with menstrual pain. I'd recommend starting with one tablet, as I've experienced no side effects or diarrhoea.
Read More
9
Muscle stiffness alleviated
35 people found this helpful
This product is excellent for raising magnesium levels without causing diarrhoea. It has significantly helped with muscle stiffness.
Read More
0
Wasted money
14 people found this helpful
I had good experiences with magnesium in the past, but this time, there was no smell and resulted in terrible diarrhoea for both me and my partner an hour after taking it.
Diarrhea is a condition characterized by the frequent passage of loose or watery stools, which can occur due to various factors, including infections, dietary choices, and underlying health conditions. It often results from the body's response to an irritation of the gastrointestinal tract, which can be caused by viruses, bacteria, parasites, or certain medications. While most cases tend to be short-lived and resolve on their own, diarrhea can lead to dehydration, especially in vulnerable populations such as young children and the elderly.
Managing diarrhea typically involves staying hydrated by drinking clear fluids and, when necessary, replenishing lost electrolytes. In some cases, over-the-counter medications may provide relief, although it’s essential to consult a healthcare professional for persistent or severe symptoms. A focus on bland, easy-to-digest foods can also help during recovery. Remember, if diarrhea persists for more than a couple of days or is accompanied by other concerning symptoms—like high fever, severe abdominal pain, or blood in stools—seeking medical attention is crucial.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium can have an effect on digestive health, but its role in managing diarrhea is complex. Magnesium is known to have a laxative effect, especially in higher doses or in certain forms, such as magnesium citrate or magnesium sulfate. This means that while magnesium can be beneficial for individuals suffering from constipation, it may exacerbate diarrhea for those who are already experiencing loose stools.
In some cases, magnesium may be helpful in alleviating diarrhea due to its overall importance in digestive function and maintaining electrolyte balance. However, if diarrhea is persistent or severe, it's crucial to consult a healthcare professional for proper evaluation and treatment. Overall, magnesium should not be seen as a primary treatment for diarrhea, and those experiencing digestive discomfort should consider other remedies and strategies alongside any magnesium supplementation.
Based on user reviews, the time it takes to see results from taking magnesium supplements can vary significantly among individuals. Some users have reported experiencing changes or side effects such as diarrhoea shortly after starting the supplement, often within a day or two. For instance, one reviewer mentioned they suffered from diarrhoea three hours after taking their first dose Read Review. Another user noted they encountered persistent diarrhoea after just three days, ultimately deciding to stop taking the product Read Review.
On the other hand, some users report no issues with diarrhoea and instead feel improvements in other areas of health, such as better sleep and muscle relaxation. One reviewer shared that they had been taking magnesium for three weeks without issues Read Review. This variability suggests that while some may notice effects almost immediately, others might not see positive results or may experience negative ones within a few days. Overall, it appears there's no standard timeframe, and results can be quite individualistic.
Research suggests that magnesium supplementation may be beneficial for managing certain types of diarrhea, particularly secretory diarrhea associated with cholera and conditions linked to magnesium deficiency. A study showed that increasing magnesium levels significantly inhibits chloride secretion in intestinal cells, which is critical during diarrhea episodes, achieving a reduction in fluid loss during cholera by 40% in mouse models [1]. Additionally, another investigation involving patients with HNF1B syndrome, where low magnesium levels often lead to gastrointestinal issues, found that magnesium supplementation significantly improved diarrhea symptoms in affected individuals, underscoring the importance of addressing magnesium deficiency in related conditions [2].
However, it's worth noting that while magnesium typically does not cause significant gastrointestinal issues, a study analyzing data from various studies found that most participants did not report diarrhea even at high supplementation doses [3]. Conversely, when magnesium was used in conjunction with naldemedine, there was an increase in the frequency of diarrhea among patients [6]. Hence, while magnesium can play a positive role in managing diarrhea through various mechanisms, its effects can vary based on individual health circumstances and the form of diarrhea being treated.
Based on user reviews, many individuals have reported a variety of improvements in their symptoms after taking magnesium supplements. A significant number of users have noted enhanced relaxation and improved sleep quality, identifying a reduction in muscle tension and menstrual pain. For instance, one user mentioned feeling a gradual relaxation that was especially helpful before bed and noticed significant relief from menstrual cramps Read Review. Others have highlighted the product's effectiveness in alleviating muscle stiffness without gastrointestinal side effects Read Review.
Conversely, there are users who have unfortunately experienced adverse reactions, particularly gastrointestinal discomfort, such as diarrhoea. Some have found that switching to a more absorbable form of magnesium, like magnesium glycinate, reduced these side effects Read Review. Overall, while many users report beneficial effects such as better relaxation, enhanced sleep, and reduced pain, it's important to note that individual results can vary widely, with some facing unexpected side effects Read Review. As always, consulting with a healthcare professional before starting any new supplement is advisable.
Users have reported mixed experiences regarding the combination of magnesium supplements with other supplements while handling diarrhea. Some reviewers highlighted that switching to more absorbable forms, like magnesium glycinate, significantly reduced gastrointestinal side effects, including diarrhea. For example, one user specifically noted that magnesium glycinate does not cause diarrhea and is better tolerated, even when combined with other supplements Read Review. Another user mentioned that after switching to Doctor’s Best magnesium, they no longer experienced diarrhea that they encountered with other magnesium sources Read Review.
Conversely, several individuals have reported experiencing diarrhea when taking magnesium, often suggesting a link to other supplements in their regimen. One reviewer experienced persistent diarrhea, speculating that it might be due to a combination of supplements, which hints at the complexities of individual reactions when multiple supplements are involved Read Review. Moreover, a separate user experienced severe gastrointestinal reactions, emphasizing the importance of monitoring one's response, especially when combining magnesium supplements with others Read Review. This variability underscores the importance of personal experimentation and consultation with healthcare providers to find the right combination that minimizes side effects.
According to recent research, magnesium supplementation shows promise as a viable treatment option for managing diarrhea, especially in cases linked to cholera and other gastrointestinal disorders. One study highlighted that increasing magnesium levels could inhibit chloride secretion in intestinal cells by up to 65%, leading to a significant reduction in fluid loss that typically accompanies diarrhea. Specifically, when magnesium was administered in mouse models, it resulted in a 40% decrease in fluid loss associated with cholera, pointing to its potential efficacy in treating secretory diarrhea ([1]).
In adults, multiple studies have also suggested that higher doses of magnesium, even up to 1200 mg daily, do not significantly increase the occurrence of diarrhea. In fact, many participants in these studies reported no adverse gastrointestinal effects from magnesium supplementation ([3]). This underscores the argument that magnesium supplementation could be safely utilized to address diarrhea, particularly in individuals with low magnesium levels due to certain health conditions, as demonstrated in cases involving patients with HNF1B syndrome where improving magnesium levels led to relief from diarrhea symptoms ([2]). Although more targeted research may further define optimal dosing strategies, current findings support magnesium’s beneficial role in managing diarrheal conditions.
0
Gastrointestinal upset
5 people found this helpful
I started with one tablet at night, but after two days I had diarrhoea three hours later. I can't imagine the effects of taking two tablets twice daily.
0
No effect noted
7 people found this helpful
My mum hasn't noticed any difference, and after three days of using it, I experienced diarrhoea and stopped taking the product.
9
No diarrhea
2 people found this helpful
I had issues with other magnesium supplements causing diarrhoea, but after switching to Doctor's High Absorption Magnesium, I no longer experience it. I feel great and plan to continue using this product long-term.
9
No diarrhoea concerns
50 people found this helpful
After taking this magnesium, I feel a gradual relaxation physically and mentally, especially helpful before bed. It alleviates muscle tension and has helped with menstrual pain. I'd recommend starting with one tablet, as I've experienced no side effects or diarrhoea.
9
Muscle stiffness alleviated
35 people found this helpful
This product is excellent for raising magnesium levels without causing diarrhoea. It has significantly helped with muscle stiffness.
0
Wasted money
14 people found this helpful
I had good experiences with magnesium in the past, but this time, there was no smell and resulted in terrible diarrhoea for both me and my partner an hour after taking it.
9
No diarrhoea issues
3 people found this helpful
Magnesium glycinate is the easiest to absorb and least likely to cause diarrhoea. It has additional benefits from glycine, promoting healthy insulin sensitivity and calming the nervous system. A great product at a good price.
0
Causes diarrhoea
2 people found this helpful
Though I aimed to alleviate migraines with this supplement, it has instead resulted in persistent diarrhoea, possibly due to a combination of other supplements I am taking.
0
Severe diarrhoea
3 people found this helpful
This drug is awful. I experienced severe abdominal pain and diarrhoea. Once I stopped taking it, everything returned to normal, and my bowel movements normalised after three days.
9.5
Magnesium shows potential for diarrhea
Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells.
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
4
Magnesium and diarrhea analysis
Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults.
We explored how magnesium supplementation affects diarrhea, particularly in adults. In recent research, we carefully reviewed data from intervention studies conducted between 1997 and 2022, focusing mainly on single-ingredient magnesium products. Our goal was to determine whether higher doses of magnesium cause significant gastrointestinal issues, especially diarrhea, which had previously shaped the established upper intake limit.
The findings were enlightening. Out of ten studies we analyzed, including five meta-analyses and five randomized controlled trials, seven indicated no significant difference in diarrhea incidents between those receiving magnesium and those given a placebo. It was interesting to note that even at doses as high as 1200 mg per day, participants generally did not report diarrhea.
When reviewing adverse event data reported to the FDA, we found just 40 cases of gastrointestinal issues linked to magnesium supplementation. Quite tellingly, only one-third of these involved complaints about diarrhea. This suggests that the concern regarding magnesium causing significant gastrointestinal problems may be overstated.
Overall, our evaluation indicates that adults can often consume magnesium supplements above the current upper intake level without significant adverse effects related to diarrhea. This opens up opportunities for increasing magnesium intake, which could help address inadequacies in this essential nutrient for many individuals.
We investigated the effects of naldemedine, a medication often used to treat opioid-induced constipation, in combination with magnesium oxide (MgO) and other laxatives during hospital stays. Our study focused on how these treatments affected daily bowel movements and the occurrence of diarrhea.
Analysis of 93 inpatients who received at least four doses of naldemedine revealed that the addition of magnesium or other laxatives significantly increased the average daily defecation counts when compared to naldemedine alone.
However, we also noted that the combination treatments were associated with higher rates of diarrhea. This suggests that while magnesium might enhance bowel movement frequency, it could also lead to more diarrhea, which is an important consideration for treatment.
Therefore, we concluded that introducing naldemedine either alone or with magnesium could be beneficial, but healthcare providers should carefully monitor for signs of diarrhea and adjust treatments as needed.
References
de Souza Goncalves L, Chu T, Master R, Chhetri PD, Gao Q, et al. Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells. J Clin Invest. 2024;134. doi:10.1172/JCI171249
Wang Y, Xiao X, Lin Q, Song R, Wang X, et al. Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia. J Diabetes Investig. 2024;15:121. doi:10.1111/jdi.14084
Costello R, Rosanoff A, Nielsen F, West C. Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults. Adv Nutr. 2023;14:973. doi:10.1016/j.advnut.2023.06.008
Kamali F, Jamee M, Sayer JA, Sadeghi-Bojd S, Golchehre Z, et al. Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature. CEN Case Rep. 2023;12:413. doi:10.1007/s13730-023-00785-8
Cao S, Huang K, Wen X, Gao J, Cui B, et al. Dietary supplementation with potassium-magnesium sulfate modulates the antioxidant capacity, immunity, and gut microbiota in weaned piglets. Front Microbiol. 2022;13:961989. doi:10.3389/fmicb.2022.961989
Takemura M, Niki K, Miyaguchi S, Ueda M. Naldemedine-laxative combination: retrospective inpatient study. BMJ Support Palliat Care. 2024;13:e816. doi:10.1136/spcare-2022-003685
Sarkar KK, Mitra T, Rahman MA, Raja IM, Aktaruzzaman M, et al. Bioactivities of (Wall.) and Study against Cyclooxygenase Enzymes. Biomed Res Int. 2022;2022:1331758. doi:10.1155/2022/1331758