Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.4
USERS' SCORE
Good
Based on 12 Reviews
8.2
Supplement Facts
Serving Size: 1 scoop (~2 grams)
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
9
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Read More
9
We investigated how magnesium (Mg) affects the severity of autoimmune lupus in mice. By feeding MRL/lpr female mice a standard or high magnesium diet for nine weeks, we measured impacts on skin lesions and pathogenic autoantibodies.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
Read More
8
Magnesium shows promise for NMOSD
Our investigation focused on how magnesium L-threonate might help those with neuromyelitis optica spectrum disorder (NMOSD).
We examined both mice and cultured human cells to see if long-term magnesium treatment could reduce neuroinflammation, demyelination, and strengthen the blood-brain barrier.
The results were promising; magnesium supplementation appeared to alleviate damage linked to NMOSD by improving blood-brain barrier integrity and dampening inflammation.
This suggests magnesium could be a novel approach to treating NMOSD.
We examined both mice and cultured human cells to see if long-term magnesium treatment could reduce neuroinflammation, demyelination, and strengthen the blood-brain barrier.
The results were promising; magnesium supplementation appeared to alleviate damage linked to NMOSD by improving blood-brain barrier integrity and dampening inflammation.
This suggests magnesium could be a novel approach to treating NMOSD.
Read More
Most Useful Reviews
9
Improved immunity
8 people found this helpful
I appreciate this chelated magnesium powder, which is highly absorbable and free from fillers. It's beneficial for my autoimmune disorder and overall health. Although the taste is unpleasant when mixed with water, I prefer diluting it with juice or lemon. Since using it, my sleep and immunity have noticeably improved, alongside better digestive health and skin quality. It's essential for me and my family, especially for heart health in older age and my gallbladder issues.
Read More
9
Alleviates cramps
3 people found this helpful
This magnesium is my go-to. The taste took some getting used to, but I now enjoy its benefits. I drink it in the evening and have noticed substantial relief from leg cramps and a calming effect. As it’s more economical than capsule alternatives, I’ll definitely be ordering again.
Read More
9
Restores sleep
7 people found this helpful
I tried this magnesium powder as I was feeling overwhelmingly anxious and struggled with sleep. After several days of taking it in the evening, my sleep improved dramatically, and my nerves felt more balanced. I recommend it to anyone facing similar issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.4
- All Researches
9
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Read More
9
We investigated how magnesium (Mg) affects the severity of autoimmune lupus in mice. By feeding MRL/lpr female mice a standard or high magnesium diet for nine weeks, we measured impacts on skin lesions and pathogenic autoantibodies.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
Read More
9
We explored the potential of a new magnesium-aluminum layered double hydroxide combined with nano-ceria in treating rheumatoid arthritis (RA). This innovative therapy targets the unhealthy immune environment and the harmful buildup of hydrogen ions associated with RA. By neutralizing excess acidity, we observed improved immune responses, encouraging the body to heal damaged bones. This approach showed promising results in mice models, indicating it may be a viable future treatment for managing RA effectively.
Read More
9
Magnesium aids arthritis through immunity
We explored the effects of a high magnesium diet on rheumatoid arthritis using two mouse models. Our findings suggest that magnesium can significantly reduce arthritis severity and joint damage, while also promoting immune cell types that help combat inflammation.
Interestingly, these benefits seem to hinge on an immune mediator called IL-10 and changes in the gut microbiome, such as increased beneficial bacteria. While our results are promising, it is important to recognize that the protective effects depend on sufficient levels of IL-10, indicating that the relationship between magnesium and immune regulation is quite intricate.
Interestingly, these benefits seem to hinge on an immune mediator called IL-10 and changes in the gut microbiome, such as increased beneficial bacteria. While our results are promising, it is important to recognize that the protective effects depend on sufficient levels of IL-10, indicating that the relationship between magnesium and immune regulation is quite intricate.
Read More
9
Magnesium mitigates MS-related mood issues
We investigated the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression in multiple sclerosis (MS), a disease often accompanied by these mood disorders. Our findings indicated that MgH treatment significantly improved anxiety and depression-like behaviors in mice with experimental autoimmune encephalomyelitis (EAE).
Additionally, MgH reduced disease severity and inflammatory damage. The proposed mechanism behind these effects involves modulation of microglial polarization and reduced oxidative stress. Thus, MgH shows promise as a potential treatment for psychiatric issues associated with MS.
Additionally, MgH reduced disease severity and inflammatory damage. The proposed mechanism behind these effects involves modulation of microglial polarization and reduced oxidative stress. Thus, MgH shows promise as a potential treatment for psychiatric issues associated with MS.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved immunity
8 people found this helpful
I appreciate this chelated magnesium powder, which is highly absorbable and free from fillers. It's beneficial for my autoimmune disorder and overall health. Although the taste is unpleasant when mixed with water, I prefer diluting it with juice or lemon. Since using it, my sleep and immunity have noticeably improved, alongside better digestive health and skin quality. It's essential for me and my family, especially for heart health in older age and my gallbladder issues.
Read More
9
Alleviates cramps
3 people found this helpful
This magnesium is my go-to. The taste took some getting used to, but I now enjoy its benefits. I drink it in the evening and have noticed substantial relief from leg cramps and a calming effect. As it’s more economical than capsule alternatives, I’ll definitely be ordering again.
Read More
9
Restores sleep
7 people found this helpful
I tried this magnesium powder as I was feeling overwhelmingly anxious and struggled with sleep. After several days of taking it in the evening, my sleep improved dramatically, and my nerves felt more balanced. I recommend it to anyone facing similar issues.
Read More
7.5
Better sleep quality
7 people found this helpful
This magnesium product has significantly improved my well-being. I enjoyed its convenient measuring spoon for better mixing. After three to four days, I noticed enhanced sleep quality. The deeper, dreamless sleep has helped reduce irritability, making it easier to face daily challenges. Such positive effects motivate me to reorder this effective magnesium.
Read More
9
Enhanced calm
4 people found this helpful
Having tried various magnesium supplements, I found this one effective despite its bitter taste. Initially concerning, my deteriorating mental state meant I needed a reliable solution. The calming effect has made a significant difference in my life, making me committed to using this powder continually.
Read More
Frequently Asked Questions
7.5
Better sleep quality
7 people found this helpful
This magnesium product has significantly improved my well-being. I enjoyed its convenient measuring spoon for better mixing. After three to four days, I noticed enhanced sleep quality. The deeper, dreamless sleep has helped reduce irritability, making it easier to face daily challenges. Such positive effects motivate me to reorder this effective magnesium.
9
Improved sleep quality
I chose this magnesium due to its better absorption and trusted brand. After struggling with restless sleep post-Covid, I noticed an immediate improvement after just two days of taking it. I slept soundly through the night! I’ve now been using it for a month and it clearly benefits my nervous system. I suspect I have a significant magnesium deficiency as I've felt much better since starting this.
7.5
Reduces stress
4 people found this helpful
This magnesium powder dissolves easily in water and has an indistinct taste. I was pleased with the included measuring spoon and noticed results after two weeks. I sleep better now and manage stress more effectively. This product is far superior to tablets, making it my preferred choice.
7.5
Improved relaxation
3 people found this helpful
This magnesium powder easily dissolves in water and has a mild taste. I appreciated the measuring spoon included in the jar. After two weeks, I experienced better sleep and reduced stress, especially compared to tablets. This product has become my favourite.
9
Restores sleep
7 people found this helpful
I tried this magnesium powder as I was feeling overwhelmingly anxious and struggled with sleep. After several days of taking it in the evening, my sleep improved dramatically, and my nerves felt more balanced. I recommend it to anyone facing similar issues.
9
Improved immunity
8 people found this helpful
I appreciate this chelated magnesium powder, which is highly absorbable and free from fillers. It's beneficial for my autoimmune disorder and overall health. Although the taste is unpleasant when mixed with water, I prefer diluting it with juice or lemon. Since using it, my sleep and immunity have noticeably improved, alongside better digestive health and skin quality. It's essential for me and my family, especially for heart health in older age and my gallbladder issues.
6
Eases anxiety
8 people found this helpful
I ordered this magnesium for the first time and can confirm its efficacy after two months. Initially, the taste made me gag, but I grew accustomed to it. Despite the unpleasant flavour, it quickly calms me after a long day, aiding my management of stress from work and my child's health struggles. I highly recommend it for its soothing properties.
7.5
Gastrointestinal improvement
2 people found this helpful
I had difficulty taking magnesium due to a severe gastrointestinal disorder, but this product has changed that for me. My condition has improved significantly, including severe insomnia. I take it mixed with vitamin C, making it palatable and effective.
9
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
9
We investigated how magnesium (Mg) affects the severity of autoimmune lupus in mice. By feeding MRL/lpr female mice a standard or high magnesium diet for nine weeks, we measured impacts on skin lesions and pathogenic autoantibodies.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
The results were encouraging: mice on the high magnesium diet showed significant reductions in skin issues and harmful anti-dsDNA antibodies. Plus, their immune systems displayed more regulatory T cells. However, there were no notable differences in other measured health indicators.
Overall, magnesium supplementation may be a cost-effective and safe complementary treatment for lupus.
8
Magnesium shows promise for NMOSD
Our investigation focused on how magnesium L-threonate might help those with neuromyelitis optica spectrum disorder (NMOSD).
We examined both mice and cultured human cells to see if long-term magnesium treatment could reduce neuroinflammation, demyelination, and strengthen the blood-brain barrier.
The results were promising; magnesium supplementation appeared to alleviate damage linked to NMOSD by improving blood-brain barrier integrity and dampening inflammation.
This suggests magnesium could be a novel approach to treating NMOSD.
We examined both mice and cultured human cells to see if long-term magnesium treatment could reduce neuroinflammation, demyelination, and strengthen the blood-brain barrier.
The results were promising; magnesium supplementation appeared to alleviate damage linked to NMOSD by improving blood-brain barrier integrity and dampening inflammation.
This suggests magnesium could be a novel approach to treating NMOSD.
References
- Toaima DN, Abdel-Maksoud KS, Atef HM, Salah NY. Magnesium, fibrinolysis and clotting interplay among children and adolescents with type 1 diabetes mellitus; potential mediators of diabetic microangiopathy. Nutr Diabetes. 2025;15:13. 10.1038/s41387-025-00368-9
- Laragione T, Harris C, Gulko PS. Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways. Nutrients. 2024;16. 10.3390/nu16234247
- Fu C, Huang L, Lian C, Yue J, Lin P, et al. Effects of long-term magnesium L-threonate supplementation on neuroinflammation, demyelination and blood-brain barrier integrity in mice with neuromyelitis optica spectrum disorder. Brain Res. 2025;1846:149234. 10.1016/j.brainres.2024.149234
- Yan Y, Yao C, Zhang B, Yang Z, Xie J, et al. Olanzapine vs. magnesium valproate vs. lamotrigine in anti-N-methyl-D-aspartic acid receptor encephalitis: a retrospective study. BMC Neurol. 2024;24:331. 10.1186/s12883-024-03811-z
- Verlato A, Laragione T, Bin S, Kim RH, Salem F, et al. Revised version with tracked changes oral Magnesium reduces levels of pathogenic autoantibodies and skin disease in murine lupus. BMC Immunol. 2024;25:58. 10.1186/s12865-024-00650-y
- Liu H, Zhang K, Xiong L. Dietary magnesium intake and rheumatoid arthritis patients' all-cause mortality: evidence from the NHANES database. J Health Popul Nutr. 2024;43:112. 10.1186/s41043-024-00597-1
- Fu H, Guo Y, Fang W, Wang J, Hu P, et al. Anti-Acidification and Immune Regulation by Nano-Ceria-Loaded Mg-Al Layered Double Hydroxide for Rheumatoid Arthritis Therapy. Adv Sci (Weinh). 2024;11:e2307094. 10.1002/advs.202307094
- Fang J, Cao T, Liu C, Wang D, Zhang H, et al. Association between magnesium, copper, and potassium intakes with risk of rheumatoid arthritis: a cross-sectional study from National Health and Nutrition Examination Survey (NHANES). BMC Public Health. 2023;23:2085. 10.1186/s12889-023-16906-y
- Laragione T, Harris C, Azizgolshani N, Beeton C, Bongers G, et al. Magnesium increases numbers of Foxp3+ Treg cells and reduces arthritis severity and joint damage in an IL-10-dependent manner mediated by the intestinal microbiome. EBioMedicine. 2023;92:104603. 10.1016/j.ebiom.2023.104603
- Li Z, Chen K, Shao Q, Lu H, Zhang X, et al. Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress. J Neuroinflammation. 2023;20:16. 10.1186/s12974-023-02696-y
