Last update
5/11/2025
Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 12 Reviews
8.2
Supplement Facts
Serving Size:   1 scoop (~2 grams)
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%

Top Medical Research Studies

8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More

Most Useful Reviews

9
Positive effect
The composition is good, and I bought it chiefly for its effectiveness. I have enjoyed sound sleep without leg cramps and a notable absence of fatigue, which re-emerged when I temporarily stopped taking it. Resuming led to a surprisingly cheerful mood the following day.
Read More
9
Calmer and relaxed
I am thrilled with this product! Having suffered from chronic stress and insomnia, my doctor recommended magnesium. This powder mixes well and has a pleasant lemon taste. Within a few days, I felt calmer, slept better, and even found relief from muscle aches after workouts. Highly recommend for anyone looking to improve their overall health and mood!
Read More
7.5
Well absorbed
This magnesium chelate is excellently absorbed and does not irritate the stomach. Although the taste is not very pleasing, its efficacy in alleviating fatigue is swift, benefiting muscle function and nervous system health.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
  • All Researches
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Positive effect
The composition is good, and I bought it chiefly for its effectiveness. I have enjoyed sound sleep without leg cramps and a notable absence of fatigue, which re-emerged when I temporarily stopped taking it. Resuming led to a surprisingly cheerful mood the following day.
Read More
9
Calmer and relaxed
I am thrilled with this product! Having suffered from chronic stress and insomnia, my doctor recommended magnesium. This powder mixes well and has a pleasant lemon taste. Within a few days, I felt calmer, slept better, and even found relief from muscle aches after workouts. Highly recommend for anyone looking to improve their overall health and mood!
Read More
7.5
Well absorbed
This magnesium chelate is excellently absorbed and does not irritate the stomach. Although the taste is not very pleasing, its efficacy in alleviating fatigue is swift, benefiting muscle function and nervous system health.
Read More
9
Energized daily
This product is excellent. With just 100mg a day, I feel invigorated and my chronic fatigue remains under control.
Read More
9
Post-exercise relief
I keep this product at home constantly. It has proven invaluable for relieving post-exercise fatigue and cramps, contributing positively to my recovery and overall nerves.
Read More

Frequently Asked Questions

7.5
Increased energy
Very pleased with the fast delivery and high-quality packaging. There were no damages, and the dosage is excellent, made from natural herbal ingredients. The capsules are a tad large, but swallowing is easy, and they taste of citrus. I take one capsule daily with meals, accompanied by vitamin D3+K2, magnesium, and vitamin B6. After ten days of use, I’ve noticed a significant boost in my energy levels; previous headaches and fatigue have subsided, and my mood remains elevated. I highly recommend it, especially for those interested in sports or following a diet, as omega-3 rejuvenates the body effectively.
9
Calmer and relaxed
I am thrilled with this product! Having suffered from chronic stress and insomnia, my doctor recommended magnesium. This powder mixes well and has a pleasant lemon taste. Within a few days, I felt calmer, slept better, and even found relief from muscle aches after workouts. Highly recommend for anyone looking to improve their overall health and mood!
6
Muscle pain relief
I bought this magnesium to alleviate muscle aches and fatigue. After a month, I’ve noticed slight improvements in muscle pain as I increased my workouts, but the taste of this powder mixed in water is horrid. I will probably opt for pills next time, as the flavour is difficult to mask.
9
Positive effect
The composition is good, and I bought it chiefly for its effectiveness. I have enjoyed sound sleep without leg cramps and a notable absence of fatigue, which re-emerged when I temporarily stopped taking it. Resuming led to a surprisingly cheerful mood the following day.
9
Post-exercise relief
I keep this product at home constantly. It has proven invaluable for relieving post-exercise fatigue and cramps, contributing positively to my recovery and overall nerves.
7.5
Quality issue
This magnesium works effectively, but the flavour is a challenge to endure. I’m switching to capsules for convenience. It seems beneficial for my fatigue at this point.
9
Energized daily
This product is excellent. With just 100mg a day, I feel invigorated and my chronic fatigue remains under control.
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.

References

  1. Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. 10.1186/1472-6882-11-87
  2. Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
  3. Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
  4. Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
  5. Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.
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