We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
Read More
8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
Read More
9
Magnesium improves diarrhea-related symptoms
Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature.
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
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Most Useful Reviews
9
No diarrhoea experienced
28 people found this helpful
Best magnesium I have tried! It tastes just fine. I have a problem with magnesium absorption and take at least 1600mg daily, including about 400mg transdermal. I’ve tried many types, including ReMag, which caused diarrhoea at the high doses I require. MegaMag is decent, but I worry about lead, arsenic and mercury at those doses. This magnesium does not cause diarrhoea, and unlike some reviewers, I find the taste quite acceptable. I take a couple of scoops in water with sea salt and potassium three times a day and I'm very satisfied!
Read More
7.5
No diarrhoea risk
18 people found this helpful
Magnesium chelate is excellent! Since it’s in powder form, it is quickly absorbed without any chemical fillers. Unlike magnesium citrate, this product alleviates the concern of diarrhoea and is the most reliable choice for magnesium deficiency. I typically purchase two at once and if I drink water with calcium after dinner, I enjoy deep sleep and wake feeling refreshed!
Read More
9
No diarrhoea noted
7 people found this helpful
I decided to try this new powdered magnesium. The taste was terrible at first, although I eventually got used to the sweet aftertaste. Magnesium glycinate is a preferred form of chelated magnesium as it quickly restores magnesium levels in the body and doesn't cause diarrhoea.
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
Read More
9
Magnesium improves diarrhea-related symptoms
Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature.
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
Read More
9
Magnesium reduces diarrhea incidence
Dietary supplementation with potassium-magnesium sulfate modulates the antioxidant capacity, immunity, and gut microbiota in weaned piglets.
In our exploration of how potassium-magnesium sulfate (PMS) impacts diarrhea in weaned piglets, we set out to understand its effects on growth performance, immunity, and gut health. A total of 216 piglets were divided into six groups, with varying levels of PMS in their diets.
Our findings revealed some compelling results: the addition of PMS significantly reduced the diarrhea rate among the piglets. Notably, when we included 0.3% PMS in their diet, we observed improved antioxidant capacity, which plays a crucial role in maintaining overall gut health.
We also discovered that PMS supplementation positively influenced intestinal immunity by lowering certain inflammatory markers, further suggesting its beneficial role in digestive health. Additionally, the changes in gut bacteria composition indicated that magnesium may help foster a healthier gut environment.
Overall, our study sheds light on magnesium's potential role as a treatment option for reducing diarrhea in weaned piglets, emphasizing its effectiveness in fostering both immunity and gut health.
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9
Impact of magnesium on diarrhea
Bioactivities of (Wall.) and Study against Cyclooxygenase Enzymes.
We conducted a study to assess the effectiveness of magnesium in treating diarrhea, particularly focusing on its role in extracts from (Wall.) leaves. To evaluate this, we utilized several tests that mimic diarrhea conditions. Our findings showed that while magnesium was mentioned in connection with the extracts, it was administered alongside other treatments. This means we're not entirely sure how much of the anti-diarrheal effect was due to magnesium itself.
In our tests, the methanol extract of (Wall.) leaves was particularly noteworthy, showing significant inhibition of diarrhea at a dose of 400 mg/kg. However, the role of magnesium in this context remains ambiguous since it wasn't given alone. In essence, while the extract worked well against diarrhea, the individual contribution of magnesium to this benefit is unclear.
Overall, we support the traditional use of (Wall.) plants in managing diarrhea and pain, but we need more focused research to isolate the effects of magnesium.
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8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
Best magnesium I have tried! It tastes just fine. I have a problem with magnesium absorption and take at least 1600mg daily, including about 400mg transdermal. I’ve tried many types, including ReMag, which caused diarrhoea at the high doses I require. MegaMag is decent, but I worry about lead, arsenic and mercury at those doses. This magnesium does not cause diarrhoea, and unlike some reviewers, I find the taste quite acceptable. I take a couple of scoops in water with sea salt and potassium three times a day and I'm very satisfied!
Read More
7.5
No diarrhoea risk
18 people found this helpful
Magnesium chelate is excellent! Since it’s in powder form, it is quickly absorbed without any chemical fillers. Unlike magnesium citrate, this product alleviates the concern of diarrhoea and is the most reliable choice for magnesium deficiency. I typically purchase two at once and if I drink water with calcium after dinner, I enjoy deep sleep and wake feeling refreshed!
Read More
9
No diarrhoea noted
7 people found this helpful
I decided to try this new powdered magnesium. The taste was terrible at first, although I eventually got used to the sweet aftertaste. Magnesium glycinate is a preferred form of chelated magnesium as it quickly restores magnesium levels in the body and doesn't cause diarrhoea.
Read More
7.5
Less diarrhoea occurrence
3 people found this helpful
It's hard for me to drink, with a concentrated bittern-like, fishy taste. Being chelated, it’s less likely to cause diarrhoea and I can feel the benefits of magnesium. The ingredients are excellent, so I’m considering wrapping it in oblate for easier consumption, although next time I might opt for tablets.
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0
Adverse reaction.
3 people found this helpful
GAVE ME BAD DIARRHOEA! I was disappointed as I wanted this to work, but after just one pill, I experienced explosive diarrhoea. It was dreadful! I lack the courage to try again after such an experience.
Diarrhea is a condition characterized by the frequent passage of loose or watery stools, which can occur due to various factors, including infections, dietary choices, and underlying health conditions. It often results from the body's response to an irritation of the gastrointestinal tract, which can be caused by viruses, bacteria, parasites, or certain medications. While most cases tend to be short-lived and resolve on their own, diarrhea can lead to dehydration, especially in vulnerable populations such as young children and the elderly.
Managing diarrhea typically involves staying hydrated by drinking clear fluids and, when necessary, replenishing lost electrolytes. In some cases, over-the-counter medications may provide relief, although it’s essential to consult a healthcare professional for persistent or severe symptoms. A focus on bland, easy-to-digest foods can also help during recovery. Remember, if diarrhea persists for more than a couple of days or is accompanied by other concerning symptoms—like high fever, severe abdominal pain, or blood in stools—seeking medical attention is crucial.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium can have an effect on digestive health, but its role in managing diarrhea is complex. Magnesium is known to have a laxative effect, especially in higher doses or in certain forms, such as magnesium citrate or magnesium sulfate. This means that while magnesium can be beneficial for individuals suffering from constipation, it may exacerbate diarrhea for those who are already experiencing loose stools.
In some cases, magnesium may be helpful in alleviating diarrhea due to its overall importance in digestive function and maintaining electrolyte balance. However, if diarrhea is persistent or severe, it's crucial to consult a healthcare professional for proper evaluation and treatment. Overall, magnesium should not be seen as a primary treatment for diarrhea, and those experiencing digestive discomfort should consider other remedies and strategies alongside any magnesium supplementation.
Based on user reviews, many individuals report quick relief from diarrhea after switching to this magnesium supplement. Several users note that the chelated form of magnesium in particular is less likely to cause gastrointestinal issues compared to other forms, such as magnesium citrate. For example, one reviewer highlighted that after making the switch, they no longer experienced diarrhea, indicating that the supplement has helped them find relief in a short time frame Read Review.
Users also associated quicker absorption and more favorable effects on their digestive system with this specific magnesium formula. Despite some initial unpleasant experiences with taste, many found that they could adjust to the product without the accompanying side effect of diarrhea. Generally, reviewers expressed satisfaction with the supplement's performance, often implying noticeable benefits within a few days of use Read Review.
Magnesium supplementation is increasingly supported by scientific research as a potential treatment for managing diarrhea. A study focused on secretory diarrhea, particularly from cholera, revealed that magnesium significantly inhibits chloride secretion in intestinal cells, which is crucial in episodes of diarrhea. The study showed that magnesium could reduce fluid loss associated with cholera by about 40%, suggesting its efficacy during diarrheal conditions [1]. Additionally, another research highlighted that supplementation improved symptoms in patients suffering from severe diarrhea related to low magnesium levels, emphasizing the connection between magnesium deficiency and gastrointestinal issues [2].
Conversely, while magnesium appears to enhance bowel movement frequency when combined with certain medications, it may also lead to an increased incidence of diarrhea, which is an important consideration in treatment [6]. Overall, the evidence supports magnesium's positive role in treating various types of diarrhea, although practitioners should be mindful of dosage and individual patient responses to avoid adverse effects. As our understanding of magnesium's role in gastrointestinal health continues to evolve, its therapeutic potential in dietary supplementation for diarrhea management could be significant.
Based on user reviews, many individuals report noticeable improvements in their symptoms after using this magnesium supplement, with a significant number highlighting the absence of diarrhea, which has been a common issue with other forms like magnesium citrate. One user, who requires a high dosage for magnesium absorption, noted that this particular product has not caused any gastrointestinal distress, allowing them to maintain their routine comfortably Read Review. Other reviewers echoed similar sentiments, appreciating the formulation's ability to be absorbed quickly while effectively addressing magnesium deficiency without unpleasant side effects Read Review.
Several users also reported experiencing benefits for sleep and muscle relaxation, an added bonus that seems to accompany regular use of the supplement. For instance, one reviewer mentioned enjoying deeper sleep and waking up refreshed after incorporating this magnesium into their nightly routine Read Review. While taste is a frequently discussed downside, many find it tolerable enough to continue using, particularly since the relief from symptoms has proven valuable Read Review. As always, individual results can vary, so it's important to consider personal health needs and experiences when deciding to try any supplement.
Users generally report positive experiences when combining this magnesium supplement with other products, especially in terms of digestive tolerance. Many reviewers note that taking the supplement alongside additional ingredients like sea salt and potassium has not resulted in diarrhea, which has been a problem with other magnesium forms like citrate. For instance, one user shared that they consume the magnesium in water with these additives without any gastrointestinal issues, even at high doses Read Review. Another user mentioned enjoying this powder with water and calcium after dinner, which contributed to improved sleep without adverse side effects Read Review.
Overall, users appreciate the chelated form of magnesium for its reduced likelihood of causing diarrhea. Several reviews indicate that even when mixed with other supplements or liquids, this particular magnesium powder does not lead to gastrointestinal distress, a significant improvement over prior products tried. One reviewer noted they had faced no issues taking the supplement even when combining it with food and drinks, which speaks to its ease of integration into daily routines Read Review. This capacity to blend well with other supplements appears to be a key selling point for many users.
The optimal dosage of magnesium for treating diarrhea varies based on the context and severity of the condition. Research indicates that increasing magnesium levels can significantly inhibit chloride secretion in the intestinal cells, which is crucial during diarrhea episodes. In one study, administering magnesium reduced fluid loss associated with cholera by 40%, suggesting that adequate magnesium supplementation could effectively manage secretory diarrhea [1].
While specific dosage recommendations were not firmly established in the reviewed studies, evidence shows that even at high doses—up to 1200 mg per day—most participants did not report significant gastrointestinal distress or diarrhea [3]. It's essential, however, for individuals to monitor their response to supplementation and discuss effective dosage with healthcare providers, particularly in cases linked to conditions like HNF1B syndrome, where magnesium levels were noted to directly impact diarrhea symptoms [2]. Ultimately, while there isn't a one-size-fits-all answer, increased magnesium intake may provide relief from diarrhea, particularly in contexts of deficiency or specific health conditions.
9
Effective treatment
As it is a powder, it's easy to mix with protein and drink. The taste remains unchanged. I previously experienced diarrhoea, but after switching, this one hasn't caused any.
7.5
Mild diarrhoea
I regularly use this magnesium supplement, as it absorbs well and the diarrhoea isn’t severe. It aids in sleep and muscle relaxation.
9
No diarrhoea experienced
28 people found this helpful
Best magnesium I have tried! It tastes just fine. I have a problem with magnesium absorption and take at least 1600mg daily, including about 400mg transdermal. I’ve tried many types, including ReMag, which caused diarrhoea at the high doses I require. MegaMag is decent, but I worry about lead, arsenic and mercury at those doses. This magnesium does not cause diarrhoea, and unlike some reviewers, I find the taste quite acceptable. I take a couple of scoops in water with sea salt and potassium three times a day and I'm very satisfied!
7.5
No diarrhoea risk
18 people found this helpful
Magnesium chelate is excellent! Since it’s in powder form, it is quickly absorbed without any chemical fillers. Unlike magnesium citrate, this product alleviates the concern of diarrhoea and is the most reliable choice for magnesium deficiency. I typically purchase two at once and if I drink water with calcium after dinner, I enjoy deep sleep and wake feeling refreshed!
9
Powder works well
The powder is bitter, but I expected that when I tried it for the first time. The measuring spoon was included. It hasn't caused diarrhoea. I will continue to drink it.
9.5
Magnesium shows potential for diarrhea
Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells.
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
8
Magnesium improves diarrhea symptoms
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia.
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
We investigated the effects of naldemedine, a medication often used to treat opioid-induced constipation, in combination with magnesium oxide (MgO) and other laxatives during hospital stays. Our study focused on how these treatments affected daily bowel movements and the occurrence of diarrhea.
Analysis of 93 inpatients who received at least four doses of naldemedine revealed that the addition of magnesium or other laxatives significantly increased the average daily defecation counts when compared to naldemedine alone.
However, we also noted that the combination treatments were associated with higher rates of diarrhea. This suggests that while magnesium might enhance bowel movement frequency, it could also lead to more diarrhea, which is an important consideration for treatment.
Therefore, we concluded that introducing naldemedine either alone or with magnesium could be beneficial, but healthcare providers should carefully monitor for signs of diarrhea and adjust treatments as needed.
4
Magnesium and diarrhea analysis
Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults.
We explored how magnesium supplementation affects diarrhea, particularly in adults. In recent research, we carefully reviewed data from intervention studies conducted between 1997 and 2022, focusing mainly on single-ingredient magnesium products. Our goal was to determine whether higher doses of magnesium cause significant gastrointestinal issues, especially diarrhea, which had previously shaped the established upper intake limit.
The findings were enlightening. Out of ten studies we analyzed, including five meta-analyses and five randomized controlled trials, seven indicated no significant difference in diarrhea incidents between those receiving magnesium and those given a placebo. It was interesting to note that even at doses as high as 1200 mg per day, participants generally did not report diarrhea.
When reviewing adverse event data reported to the FDA, we found just 40 cases of gastrointestinal issues linked to magnesium supplementation. Quite tellingly, only one-third of these involved complaints about diarrhea. This suggests that the concern regarding magnesium causing significant gastrointestinal problems may be overstated.
Overall, our evaluation indicates that adults can often consume magnesium supplements above the current upper intake level without significant adverse effects related to diarrhea. This opens up opportunities for increasing magnesium intake, which could help address inadequacies in this essential nutrient for many individuals.
References
de Souza Goncalves L, Chu T, Master R, Chhetri PD, Gao Q, et al. Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells. J Clin Invest. 2024;134. 10.1172/JCI171249
Wang Y, Xiao X, Lin Q, Song R, Wang X, et al. Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia. J Diabetes Investig. 2024;15:121. 10.1111/jdi.14084
Costello R, Rosanoff A, Nielsen F, West C. Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults. Adv Nutr. 2023;14:973. 10.1016/j.advnut.2023.06.008
Kamali F, Jamee M, Sayer JA, Sadeghi-Bojd S, Golchehre Z, et al. Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature. CEN Case Rep. 2023;12:413. 10.1007/s13730-023-00785-8
Cao S, Huang K, Wen X, Gao J, Cui B, et al. Dietary supplementation with potassium-magnesium sulfate modulates the antioxidant capacity, immunity, and gut microbiota in weaned piglets. Front Microbiol. 2022;13:961989. 10.3389/fmicb.2022.961989
Takemura M, Niki K, Miyaguchi S, Ueda M. Naldemedine-laxative combination: retrospective inpatient study. BMJ Support Palliat Care. 2024;13:e816. 10.1136/spcare-2022-003685
Sarkar KK, Mitra T, Rahman MA, Raja IM, Aktaruzzaman M, et al. Bioactivities of (Wall.) and Study against Cyclooxygenase Enzymes. Biomed Res Int. 2022;2022:1331758. 10.1155/2022/1331758