We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
Magnesium reduces mortality in HFpEF
Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
Most Useful Reviews
7.5
High digestibility
66 people found this helpful
I ordered this for myself. I have no complaints; it's as described. The powder dissolves easily in warm water and is well-absorbed due to the chelation with amino acids. It helps with my nervous system and muscles, allowing for good sleep. I prefer this powder over encapsulated forms, as it’s effective and supports my magnesium levels, crucial for heart disease.
Read More
9
Cured nasopharyngitis
12 people found this helpful
A doctor recommended a high intake of magnesium to manage chronic nasopharyngitis. After taking this product, my wife and I felt significant improvement. Magnesium has helped with our symptoms, including migraines, and is also suggested for heart disease.
Read More
9
Life-saving support
10 people found this helpful
This magnesium has truly saved me! After experiencing severe symptoms from depleting my magnesium reserves due to vitamin D, this product made a noticeable difference within days. It’s vital for my heart health, and I've improved vastly since using it, despite the awful taste.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
8
Magnesium intake impacts heart disease risk
Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study.
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Read More
8
Magnesium and potassium reduce BP
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length.
We analyzed several clinical trials to examine how magnesium and potassium affect systolic blood pressure (SBP) in healthy individuals. Our findings showed that magnesium significantly reduced SBP, especially at lower doses (up to 360 mg/day) and longer treatment periods of over three months. Potassium also played a role but was effective at higher doses and shorter durations.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
Read More
8
Calcium-Magnesium Ratio Predicts Prognosis
Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome.
We explored how the serum calcium-magnesium ratio impacts outcomes in patients with acute coronary syndrome (ACS) by analyzing data from 1,775 individuals who underwent coronary procedures over five years.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
I ordered this for myself. I have no complaints; it's as described. The powder dissolves easily in warm water and is well-absorbed due to the chelation with amino acids. It helps with my nervous system and muscles, allowing for good sleep. I prefer this powder over encapsulated forms, as it’s effective and supports my magnesium levels, crucial for heart disease.
Read More
9
Cured nasopharyngitis
12 people found this helpful
A doctor recommended a high intake of magnesium to manage chronic nasopharyngitis. After taking this product, my wife and I felt significant improvement. Magnesium has helped with our symptoms, including migraines, and is also suggested for heart disease.
Read More
9
Life-saving support
10 people found this helpful
This magnesium has truly saved me! After experiencing severe symptoms from depleting my magnesium reserves due to vitamin D, this product made a noticeable difference within days. It’s vital for my heart health, and I've improved vastly since using it, despite the awful taste.
Read More
7.5
Heartburn relief
I appreciate this product, though the taste is quite unpleasant. Surprisingly, it alleviates heartburn, meaning I no longer need my previous medication, which is fantastic for my health, including heart disease management.
Read More
6
Gastrointestinal impact
This magnesium chelate works and calms well, though it can irritate the gastrointestinal tract. It was recommended for my heart health, and I plan to compare it with another type.
Heart disease refers to a range of conditions that affect the heart's function and overall health. This umbrella term includes various cardiovascular issues such as coronary artery disease, which is caused by the buildup of plaque in the arteries; heart rhythm problems (arrhythmias); and heart defects present at birth (congenital heart defects). Additionally, heart disease encompasses conditions related to the heart muscle, such as cardiomyopathy, and the heart's valves, which might not open or close properly. The effects of heart disease can be significant, impacting not only physical health but also quality of life, making prevention and timely medical intervention crucial.
Several risk factors contribute to the development of heart disease, including high blood pressure, high cholesterol levels, diabetes, obesity, poor diet, physical inactivity, and smoking. Genetics also play a role, as heart disease can run in families. To mitigate the risks, healthcare professionals typically recommend lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and avoiding tobacco use. For those already diagnosed with heart disease, treatment options can vary widely, ranging from lifestyle modifications to medications and, in severe cases, surgical interventions. Understanding the nature of heart disease and its risk factors is an essential step toward prevention and effective management.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is an essential mineral that plays a critical role in cardiovascular health. Research suggests that adequate magnesium intake may help reduce the risk of heart disease by maintaining normal heart rhythm, regulating blood pressure, and supporting overall vascular health. Some studies have shown that higher magnesium levels are associated with lower rates of heart attack and stroke, indicating that this mineral might have a protective effect on the heart. Additionally, magnesium helps with the transport of potassium and calcium, both of which are vital for proper heart function.
However, while magnesium supplementation may benefit those who are deficient, it is important to note that it should not be seen as a standalone treatment for heart disease. Individuals with existing heart conditions should consult their healthcare providers before making any changes to their diet or supplementation regimen. Overall, maintaining a balanced diet rich in magnesium through food sources like leafy greens, nuts, seeds, and whole grains, combined with regular physical activity, may contribute to better heart health.
Based on user reviews, many individuals report noticeable improvements in their symptoms related to heart disease within a few days of starting the supplement. For instance, one user mentioned a significant difference just days after beginning their regimen, which they attributed to the magnesium's role in managing heart health Read Review. Other users echoed similar sentiments, highlighting how quickly they felt the benefits of using magnesium for their heart-related issues.
While a few users shared that they appreciated the immediate calming effects this supplement had on their nervous system, specifically noting improvements in their sleep quality and overall health Read Review. Overall, while the timeline may vary from person to person, many users seem to notice results within a week or less, making it a potentially effective option for those managing heart disease.
Scientific research supports the use of magnesium supplements for heart health, particularly in relation to heart disease. Multiple studies have shown that higher magnesium levels are linked to a reduced risk of heart failure and adverse cardiac events. For instance, a study focusing on over 94,000 veterans found that those who took magnesium supplements had a lower heart failure risk compared to nonusers (8.0% versus 9.7%) [1]. Another investigation demonstrated that individuals with higher magnesium levels experienced significantly lower mortality rates from heart-related conditions, particularly in the context of chronic kidney disease [2]. This suggests that maintaining adequate magnesium levels may contribute positively to overall heart health.
Furthermore, magnesium supplementation has shown promise among heart failure patients. A study of nearly 2,000 patients revealed a significant reduction in 28-day mortality rates among those who received magnesium, especially in older adults and women with high blood pressure [4]. Additionally, magnesium intake has been linked to better blood sugar control in patients with coronary artery disease, which is another critical factor in managing heart health [3]. While these findings suggest a beneficial relationship between magnesium and heart health, further randomized controlled trials are necessary to fully understand these implications and optimal dosing guidelines.
Based on user reviews, many individuals have reported significant improvements in various symptoms after incorporating magnesium into their regimen. For example, one user noted that after only a few days of use, their heart health dramatically improved, particularly after suffering from magnesium depletion Read Review. Others have shared that they experienced relief from chronic conditions such as migraines and heartburn, highlighting magnesium’s versatility in alleviating these issues without the need for additional medication Read ReviewRead Review. Additionally, users have praised its calming effects, particularly noting improvements in sleep quality and overall well-being, which are crucial for managing health concerns like heart disease Read Review.
While the results can vary depending on the individual, many found that the bioavailability of chelated magnesium significantly contributed to the quick onset of benefits for their health, including muscle relaxation and nervous system support. This feedback indicates that those battling heart disease or related symptoms may find magnesium supplementation a valuable addition to their health routine Read Review. However, it is essential to keep in mind that personal experiences may differ.
Based on user reviews, many individuals report positive experiences when combining this magnesium supplement with other supplements for managing heart disease. Several users highlighted that magnesium not only supports heart health but also pairs well with other supplements, enhancing their overall effectiveness. For instance, one user noted that taking magnesium in conjunction with 5-HTP improved their sleep and overall health related to heart concerns Read Review. Another user mentioned that after being advised to increase magnesium intake, both they and their spouse saw significant improvements in their health, particularly in managing chronic conditions Read Review.
Additionally, users appreciated magnesium's calming benefits, which can be crucial for those dealing with heart disease, as stress management is a key component of heart health. One reviewer noted that their experience included alleviating symptoms like heartburn, allowing them to forgo previous medications, further supporting their heart health goals Read Review. While individual reactions can vary, the consensus suggests that combining magnesium with other treatments may provide complementary benefits for those managing heart disease.
Users report that magnesium is essential for managing heart disease, often emphasizing its importance for heart health, overall wellness, and symptom relief. Several reviews note a preference for chelated or powdered forms of magnesium, as these types are purportedly better absorbed by the body, enhancing their effectiveness. For instance, one user mentioned that they experienced a significant improvement in their heart health after incorporating chelated magnesium into their routine, stating it was crucial for their overall well-being Read Review. Another user highlighted the product's impact on their nervous system and sleep patterns, attributing these benefits to its role in supporting magnesium levels, which they deemed vital for heart disease management Read Review.
Despite differences in user experience, a consensus on dosage isn't clearly stated across the reviews. The importance of magnesium is reinforced by users who regularly incorporate it into their daily regimen. However, precise dosage recommendations were not a focal point in the feedback provided. Instead, users shared personal positive outcomes from the supplementation of magnesium, which collectively points to its perceived benefits in treating heart disease and enhancing overall health Read Review.
9
Life-saving support
10 people found this helpful
This magnesium has truly saved me! After experiencing severe symptoms from depleting my magnesium reserves due to vitamin D, this product made a noticeable difference within days. It’s vital for my heart health, and I've improved vastly since using it, despite the awful taste.
7.5
Muscle tension relief
3 people found this helpful
This magnesium works wonders before bed. It relaxes my nervous system and helps me fall asleep swiftly. I take it with 5-HTP. I wake up refreshed and optimistic, which is beneficial for managing my overall health concerns related to heart disease.
9
Cured nasopharyngitis
12 people found this helpful
A doctor recommended a high intake of magnesium to manage chronic nasopharyngitis. After taking this product, my wife and I felt significant improvement. Magnesium has helped with our symptoms, including migraines, and is also suggested for heart disease.
7.5
Heartburn relief
I appreciate this product, though the taste is quite unpleasant. Surprisingly, it alleviates heartburn, meaning I no longer need my previous medication, which is fantastic for my health, including heart disease management.
7.5
Soothing experience
1 people found this helpful
This chelated magnesium is excellent for its bioavailability and absorption. It calms my nervous system and can assist in treating conditions like heart disease and anxiety.
7.5
Well absorbed form
2 people found this helpful
This chelated magnesium is combined with amino acids and is well absorbed. Although the taste is unpleasant, it's essential for heart health, brain function, and overall immunity.
7.5
High digestibility
66 people found this helpful
I ordered this for myself. I have no complaints; it's as described. The powder dissolves easily in warm water and is well-absorbed due to the chelation with amino acids. It helps with my nervous system and muscles, allowing for good sleep. I prefer this powder over encapsulated forms, as it’s effective and supports my magnesium levels, crucial for heart disease.
7
Magnesium supplements lower heart failure risk
Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation.
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
9
Magnesium reduces mortality in HFpEF
Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
7
Magnesium improves blood sugar control
Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease.
We investigated the effect of magnesium and calcium on blood sugar levels in 11,934 patients with coronary artery disease. Our findings indicated that higher serum magnesium levels and a favorable magnesium to calcium ratio were associated with lower abnormal HbA1c levels, which reflect better blood sugar management. In contrast, calcium showed no significant association with HbA1c levels. Importantly, we found no evidence that inflammation played a role in this relationship. Overall, magnesium might be beneficial for maintaining healthy blood sugar levels in those with heart disease.
References
Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. 10.1161/JAHA.124.038870
Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. 10.1093/ckj/sfae390
Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. 10.6133/apjcn.202502_34(1).0010
Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. 10.1038/s41598-025-85931-1
Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. 10.1684/mrh.2024.0528
Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. 10.1186/s12889-024-20785-2
Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. 10.3390/nu16213617
Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. 10.1371/journal.pone.0313352
Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. 10.1038/s41598-024-74325-4
Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. 10.4244/EIJ-D-24-00055
Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. 10.1016/j.jjcc.2024.08.003
Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. 10.1093/eurjpc/zwae251
Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. 10.1684/mrh.2024.0517
Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. 10.3390/ijerph21070932
Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. 10.1080/00015385.2024.2379682
Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. 10.1186/s12951-024-02685-0