Reviewed By
Overview
SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
USERS' SCORE
Good
Based on 38 Reviews
8.2
Supplement Facts
Serving Size: 1 scoop (~2 grams)
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Read More
9
We sought to understand the effectiveness of oral magnesium in treating leg cramps experienced by pregnant women. Our study was well-structured, involving a double-blind, randomized, placebo-controlled design. It included 86 healthy pregnant women between 14 to 34 weeks of gestation who encountered leg cramps at least twice a week, and we followed them over a four-week period.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
Read More
7
We set out to investigate whether magnesium citrate could be an effective remedy for those who experience bothersome leg cramps, particularly at night. In our study, we used a randomised, double-blind, cross-over, placebo-controlled design to ensure reliable results. Participants suffering from regular leg cramps were recruited and given either magnesium citrate or a matching placebo over six weeks.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Read More
Most Useful Reviews
9
Good for sleep
8 people found this helpful
This magnesium is excellent for promoting sound sleep. Chelated forms are absorbed well and remedy deficiency symptoms. I often suffer from calf muscle cramps at night, and this magnesium helps restore order quickly. It also promotes relaxation and ensures a good night's sleep.
Read More
9
Elderly facility support
7 people found this helpful
I purchase this magnesium for my 76-year-old mother who struggles to swallow pills. Her magnesium absorption has decreased with age, leading to leg cramps. After just two days of starting this supplement, the cramps stopped entirely. She has had no digestive issues and highly recommends it.
Read More
10
Reduced leg cramps
6 people found this helpful
Excellent! Good health! I've taken this magnesium before but in capsules. I typically take about 100 mg in capsules, but here half a scoop is sufficient. In stressful situations, I take a full scoop. The effect is good; I became calmer, though I still respond actively. My sleep improved and the leg cramps really disappeared. They used to be bothersome, but now I hardly notice them. I still enjoy tea with sugar, but don’t have any other sweets. This result is fantastic! Thank you for your Likes!
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
- All Researches
9.5
We explored the effects of magnesium treatment in a unique case involving a 62-year-old woman with stage IV colon cancer undergoing oxaliplatin therapy. Shortly after her first infusion, we observed that she experienced significant neurological symptoms, including right hemibody paresthesia, muscle cramping in her right calf, and dysphonia.
To address these symptoms, she was administered intravenous magnesium sulfate along with calcium gluconate. Remarkably, within three hours, all her symptoms resolved. While this case suggests that magnesium can provide relief from cramps and other neurological side effects, it is important to note that magnesium was used in conjunction with other medications, making it challenging to assess its isolated effectiveness.
For future doses, the oxaliplatin was adjusted by reducing the dose and extending the infusion duration, which minimized her symptoms to occasional mild paresthesia. In summary, while magnesium showed promise in this case, further research is needed to determine its specific impact on leg cramps in a clearer, more controlled manner.
To address these symptoms, she was administered intravenous magnesium sulfate along with calcium gluconate. Remarkably, within three hours, all her symptoms resolved. While this case suggests that magnesium can provide relief from cramps and other neurological side effects, it is important to note that magnesium was used in conjunction with other medications, making it challenging to assess its isolated effectiveness.
For future doses, the oxaliplatin was adjusted by reducing the dose and extending the infusion duration, which minimized her symptoms to occasional mild paresthesia. In summary, while magnesium showed promise in this case, further research is needed to determine its specific impact on leg cramps in a clearer, more controlled manner.
Read More
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Read More
9
We sought to understand the effectiveness of oral magnesium in treating leg cramps experienced by pregnant women. Our study was well-structured, involving a double-blind, randomized, placebo-controlled design. It included 86 healthy pregnant women between 14 to 34 weeks of gestation who encountered leg cramps at least twice a week, and we followed them over a four-week period.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
Read More
7
We set out to investigate whether magnesium citrate could be an effective remedy for those who experience bothersome leg cramps, particularly at night. In our study, we used a randomised, double-blind, cross-over, placebo-controlled design to ensure reliable results. Participants suffering from regular leg cramps were recruited and given either magnesium citrate or a matching placebo over six weeks.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Read More
7
Magnesium shows potential benefits
We explored the effectiveness of magnesium treatment for leg cramps during pregnancy through a review of five randomized trials involving 352 women.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
Read More
User Reviews
USERS' SCORE
Good
Based on 38 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Good for sleep
8 people found this helpful
This magnesium is excellent for promoting sound sleep. Chelated forms are absorbed well and remedy deficiency symptoms. I often suffer from calf muscle cramps at night, and this magnesium helps restore order quickly. It also promotes relaxation and ensures a good night's sleep.
Read More
9
Elderly facility support
7 people found this helpful
I purchase this magnesium for my 76-year-old mother who struggles to swallow pills. Her magnesium absorption has decreased with age, leading to leg cramps. After just two days of starting this supplement, the cramps stopped entirely. She has had no digestive issues and highly recommends it.
Read More
10
Reduced leg cramps
6 people found this helpful
Excellent! Good health! I've taken this magnesium before but in capsules. I typically take about 100 mg in capsules, but here half a scoop is sufficient. In stressful situations, I take a full scoop. The effect is good; I became calmer, though I still respond actively. My sleep improved and the leg cramps really disappeared. They used to be bothersome, but now I hardly notice them. I still enjoy tea with sugar, but don’t have any other sweets. This result is fantastic! Thank you for your Likes!
Read More
10
Cramps are gone
4 people found this helpful
I found this chelated magnesium from Doctor Best to be easily digestible and effective. Although I initially bought it in powder, I quickly swallow it with water, avoiding the bitter taste. It significantly enhances sleep quality, and my leg cramps have vanished, indicating a potential deficiency.
Read More
9
Better sleep
4 people found this helpful
Helps me get a good night's sleep. I use magnesium before going to bed, and it aids in achieving restful sleep without muscle cramps. It's also beneficial for my gut health.
Read More
Frequently Asked Questions
9
Elderly facility support
7 people found this helpful
I purchase this magnesium for my 76-year-old mother who struggles to swallow pills. Her magnesium absorption has decreased with age, leading to leg cramps. After just two days of starting this supplement, the cramps stopped entirely. She has had no digestive issues and highly recommends it.
8
Muscle cramping relief
182 people found this helpful
Magnesium is essential for regulating various bodily processes. Since taking it, my sleep has improved significantly, and my muscles have stopped cramping. The positive effects of magnesium became apparent after just a few days, despite an unpleasant taste.
9
Effective dosage
1 people found this helpful
This magnesium is excellent for muscle cramps. I take two scoops daily—one in the morning and another a couple of hours before bed. I used to wake up multiple times each night with leg cramps, but after two weeks of this regimen, the cramps are gone, and I sleep more deeply.
10
Effective product
3 people found this helpful
Though I initially disliked the taste, I've grown accustomed to it. I appreciate how effective this magnesium is; my leg cramps have disappeared. It’s gentle on the stomach and creates a relaxing effect in the evening, all at a better price than capsule alternatives. I plan to reorder.
9
Better sleep
4 people found this helpful
Helps me get a good night's sleep. I use magnesium before going to bed, and it aids in achieving restful sleep without muscle cramps. It's also beneficial for my gut health.
9
No more cramps
4 people found this helpful
I add this to my smoothies. I take magnesium for nighttime leg cramps, and it works brilliantly. I ensure I don't exceed 500 mg at a time; however, it effectively eliminates my cramps. I never experience them anymore – yay!
10
Pain relief
1 people found this helpful
Cramping is painful, but this product works well with orange cordial. I no longer experience cramps when using this.
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
2
We examined the effectiveness of magnesium supplements in reducing leg cramps during pregnancy, a common issue that affects up to half of pregnant women. Four randomized controlled trials were included in our analysis, with a total of 332 participants, which compared magnesium treatment to a placebo.
Our findings showed that magnesium supplementation did not significantly decrease the frequency of leg cramps compared to the control group. The weighted mean difference was -0.47, which indicates that while there may be a slight improvement, it was not considered statistically meaningful.
Moreover, magnesium did not help women recover from leg cramps more effectively than the placebo, and there were no significant side effects reported. Overall, we found that oral magnesium supplementation is not effective in treating leg cramps during pregnancy.
Our findings showed that magnesium supplementation did not significantly decrease the frequency of leg cramps compared to the control group. The weighted mean difference was -0.47, which indicates that while there may be a slight improvement, it was not considered statistically meaningful.
Moreover, magnesium did not help women recover from leg cramps more effectively than the placebo, and there were no significant side effects reported. Overall, we found that oral magnesium supplementation is not effective in treating leg cramps during pregnancy.
3
We examined the effectiveness of magnesium supplementation for preventing skeletal muscle cramps through a systematic review of several studies. Seven trials involving a total of 406 participants were included, with some studies focusing on women experiencing leg cramps during pregnancy and others on adults with idiopathic cramps.
Overall, we found that magnesium supplementation did not offer a significant benefit in reducing the frequency or intensity of cramps for older adults. The data on idiopathic cramps showed only minor changes that weren’t statistically significant. Specifically, the difference in the number of cramps per week between magnesium and placebo groups was negligible, suggesting that it may not provide any clinically meaningful relief.
For pregnant women experiencing leg cramps, the results were mixed, indicating a need for further research. It’s clear from the trials that magnesium might not be the miracle solution that many hope for when it comes to leg cramps. We also noted that any side effects reported were similar to those seen with placebo, reinforcing the idea that magnesium poses little risk.
Overall, we found that magnesium supplementation did not offer a significant benefit in reducing the frequency or intensity of cramps for older adults. The data on idiopathic cramps showed only minor changes that weren’t statistically significant. Specifically, the difference in the number of cramps per week between magnesium and placebo groups was negligible, suggesting that it may not provide any clinically meaningful relief.
For pregnant women experiencing leg cramps, the results were mixed, indicating a need for further research. It’s clear from the trials that magnesium might not be the miracle solution that many hope for when it comes to leg cramps. We also noted that any side effects reported were similar to those seen with placebo, reinforcing the idea that magnesium poses little risk.
4
We explored how magnesium might help alleviate leg cramps during pregnancy through a systematic review of six randomized controlled trials, involving 390 women in total. These studies compared magnesium with placebo or no treatment to see if it could reduce the frequency and intensity of these cramps.
Interestingly, the results showed mixed outcomes. While some trials indicated a slight reduction in the number of leg cramps after magnesium treatment, it wasn't consistent across the board. For example, one trial noted that magnesium could lead to a 50% reduction in cramps, while others found no significant difference compared to placebo.
We also observed that the overall quality of the evidence was low, mainly due to small sample sizes and design limitations. The studies did not comprehensively assess the safety of magnesium either, as side effects were only reported for magnesium versus placebo. Additionally, it was worth noting that other interventions like calcium and vitamin B were also tested but did not show a clear advantage over magnesium.
In conclusion, our findings leave us with an unclear picture of magnesium's effectiveness against leg cramps in pregnant women. For a more definitive answer, more rigorous studies are warranted, especially those exploring different methodologies, including non-drug therapies.
Interestingly, the results showed mixed outcomes. While some trials indicated a slight reduction in the number of leg cramps after magnesium treatment, it wasn't consistent across the board. For example, one trial noted that magnesium could lead to a 50% reduction in cramps, while others found no significant difference compared to placebo.
We also observed that the overall quality of the evidence was low, mainly due to small sample sizes and design limitations. The studies did not comprehensively assess the safety of magnesium either, as side effects were only reported for magnesium versus placebo. Additionally, it was worth noting that other interventions like calcium and vitamin B were also tested but did not show a clear advantage over magnesium.
In conclusion, our findings leave us with an unclear picture of magnesium's effectiveness against leg cramps in pregnant women. For a more definitive answer, more rigorous studies are warranted, especially those exploring different methodologies, including non-drug therapies.
9
We sought to understand the effectiveness of oral magnesium in treating leg cramps experienced by pregnant women. Our study was well-structured, involving a double-blind, randomized, placebo-controlled design. It included 86 healthy pregnant women between 14 to 34 weeks of gestation who encountered leg cramps at least twice a week, and we followed them over a four-week period.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
3
We evaluated the effectiveness of magnesium supplements in preventing leg cramps, a common issue especially for older adults and pregnant women. Our focus was on randomized controlled trials that compared magnesium to placebos or other treatments.
After analyzing data from 11 trials involving a total of 735 participants, we found that magnesium supplementation showed little to no significant benefit. For older adults suffering from idiopathic leg cramps, the differences in cramp frequency, intensity, and duration were minimal and not statistically significant. In one trial focused on pregnant women, the results were mixed and not conclusive.
Additionally, while some participants did report minor gastrointestinal side effects from magnesium, major adverse events were not significantly different from those who received placebo. This leads us to conclude that magnesium may not provide meaningful relief for most older adults experiencing leg cramps. For pregnant women, further studies are necessary to determine if magnesium could be effective.
Overall, the evidence suggests that more research is needed to clarify magnesium's role, especially in specific populations like pregnant women who experience cramps.
After analyzing data from 11 trials involving a total of 735 participants, we found that magnesium supplementation showed little to no significant benefit. For older adults suffering from idiopathic leg cramps, the differences in cramp frequency, intensity, and duration were minimal and not statistically significant. In one trial focused on pregnant women, the results were mixed and not conclusive.
Additionally, while some participants did report minor gastrointestinal side effects from magnesium, major adverse events were not significantly different from those who received placebo. This leads us to conclude that magnesium may not provide meaningful relief for most older adults experiencing leg cramps. For pregnant women, further studies are necessary to determine if magnesium could be effective.
Overall, the evidence suggests that more research is needed to clarify magnesium's role, especially in specific populations like pregnant women who experience cramps.
References
- Barna O, Lohoida P, Holovchenko Y, Bazylevych A, Velychko V, et al. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps. Nutr J. 2021;20:90. 10.1186/s12937-021-00747-9
- Liu J, Song G, Zhao G, Meng T. Effect of oral magnesium supplementation for relieving leg cramps during pregnancy: A meta-analysis of randomized controlled trials. Taiwan J Obstet Gynecol. 2021;60:609. 10.1016/j.tjog.2021.05.006
- Luo L, Zhou K, Zhang J, Xu L, Yin W. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2020;12:CD010655. 10.1002/14651858.CD010655.pub3
- Garrison SR, Korownyk CS, Kolber MR, Allan GM, Musini VM, et al. Magnesium for skeletal muscle cramps. Cochrane Database Syst Rev. 2020;9:CD009402. 10.1002/14651858.CD009402.pub3
- Araújo CAL, Lorena SB, Cavalcanti GCS, Leão GLS, Tenório GP, et al. Oral magnesium supplementation for leg cramps in pregnancy-An observational controlled trial. PLoS One. 2020;15:e0227497. 10.1371/journal.pone.0227497
- Sebo P, Haller D, Cerutti B, Maisonneuve H. A prospective observational study of the main features of nocturnal leg cramps in primary care. Swiss Med Wkly. 2019;149:w20048. 10.4414/smw.2019.20048
- Roguin Maor N, Alperin M, Shturman E, Khairaldeen H, Friedman M, et al. Effect of Magnesium Oxide Supplementation on Nocturnal Leg Cramps: A Randomized Clinical Trial. JAMA Intern Med. 2017;177:617. 10.1001/jamainternmed.2016.9261
- Zhou K, West HM, Zhang J, Xu L, Li W. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2015. 10.1002/14651858.CD010655.pub2
- Sebo P, Cerutti B, Haller DM. Effect of magnesium therapy on nocturnal leg cramps: a systematic review of randomized controlled trials with meta-analysis using simulations. Fam Pract. 2014;31:7. 10.1093/fampra/cmt065
- Garrison SR, Allan GM, Sekhon RK, Musini VM, Khan KM. Magnesium for skeletal muscle cramps. Cochrane Database Syst Rev. 2012;2012:CD009402. 10.1002/14651858.CD009402.pub2
- Supakatisant C, Phupong V. Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial. Matern Child Nutr. 2015;11:139. 10.1111/j.1740-8709.2012.00440.x
- Garrison SR, Birmingham CL, Koehler BE, McCollom RA, Khan KM. The effect of magnesium infusion on rest cramps: randomized controlled trial. J Gerontol A Biol Sci Med Sci. 2011;66:661. 10.1093/gerona/glq232
- Uña E. Atypical presentation of acute neurotoxicity secondary to oxaliplatin. J Oncol Pharm Pract. 2010;16:280. 10.1177/1078155209355849
- Roffe C, Sills S, Crome P, Jones P. Randomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps. Med Sci Monit. 2002;8:CR326.
- Young GL, Jewell D. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2002.
- Frusso R, Zárate M, Augustovski F, Rubinstein A. Magnesium for the treatment of nocturnal leg cramps: a crossover randomized trial. J Fam Pract. 1999;48:868.
- Dahle LO, Berg G, Hammar M, Hurtig M, Larsson L. The effect of oral magnesium substitution on pregnancy-induced leg cramps. Am J Obstet Gynecol. 1995;173:175.
