Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy.
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.
Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
9
Thiamine deficiency linked to anorexia
Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi.
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.
After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
8
Pyridoxine reduces nausea in pregnancy
The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.
Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.
Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More
Most Useful Reviews
7.5
Nausea prevented
7 people found this helpful
It helped me! A geneticist prescribed these capsules due to my increased homocysteine levels. After two months of taking these vitamins, my levels fell, and I successfully became pregnant. I recommend taking them after meals to avoid nausea.
Read More
9
No adverse reactions
1 people found this helpful
My body reacts well to this brand of Vit B complex. So far, it’s the only one that doesn’t induce adverse reactions like nausea and frequent urination.
Read More
9
No nausea
1 people found this helpful
Buy it! Unlike most supplements, this medicine doesn’t induce any nausea for me at all. I've never missed a dose since starting it, which is an achievement considering my dislike for medication. This is an honest review. I highly recommend it.
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.
After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
9
Cariban effectively relieves pregnancy nausea
Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy.
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.
Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
8
Pyridoxine reduces nausea in pregnancy
The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.
Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.
Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More
7
Pyridoxine shows potential for PONV
Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial.
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.
Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 17 Reviews
6.4
All Reviews
Positive Reviews
Negative Reviews
7.5
Nausea prevented
7 people found this helpful
It helped me! A geneticist prescribed these capsules due to my increased homocysteine levels. After two months of taking these vitamins, my levels fell, and I successfully became pregnant. I recommend taking them after meals to avoid nausea.
Read More
9
No adverse reactions
1 people found this helpful
My body reacts well to this brand of Vit B complex. So far, it’s the only one that doesn’t induce adverse reactions like nausea and frequent urination.
Read More
9
No nausea
1 people found this helpful
Buy it! Unlike most supplements, this medicine doesn’t induce any nausea for me at all. I've never missed a dose since starting it, which is an achievement considering my dislike for medication. This is an honest review. I highly recommend it.
Read More
10
No nausea
An excellent complex with vitamins in readily available forms. Importantly, there is no nausea associated with it.
Read More
9
Nausea from capsules
Good composition, fast delivery, high-quality packaging. However, the capsules are a bit large but swallow easily. I've noticed the benefits since taking this alongside other supplements; I had frequent headaches and nausea, which have now diminished. My mood has improved significantly too, and I recommend it, especially for fitness enthusiasts.
Nausea is a sensation that often precedes vomiting and is characterized by an uneasy feeling in the stomach. It can be caused by a variety of factors, including motion sickness, certain medications, food poisoning, or underlying health conditions. The experience of nausea can range from mildly uncomfortable to intensely distressing and is often accompanied by other symptoms such as sweating, increased salivation, or a feeling of lightheadedness.
Many people experience nausea at some point in their lives, making it a common issue. Fortunately, there are several remedies and treatments available that can help alleviate this unpleasant sensation. Over-the-counter medications, home remedies like ginger tea, and lifestyle changes, such as eating smaller meals or avoiding certain triggers, can be effective in reducing nausea. However, if nausea is persistent or accompanied by severe symptoms like severe abdominal pain or fever, it’s essential to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
Vitamin B Complex has the potential to help with nausea, particularly in specific situations. There is some evidence suggesting that vitamin B6 (pyridoxine) can be effective in alleviating nausea and vomiting, especially in pregnant women experiencing morning sickness. Studies have shown that vitamin B6 may help by influencing the brain's neurotransmitters, which play a role in the nausea response. While B6 can be a useful option, it's important to consult with a healthcare provider before starting any vitamin supplementation, especially during pregnancy.
Vitamin B Complex includes a group of B vitamins, each with its unique benefits. The other B vitamins, such as B1 (thiamine), B2 (riboflavin), and B12 (cobalamin), also contribute to overall health but may not directly impact nausea. If you're considering B vitamins to help with nausea, B6 is the most relevant in this context. Always remember that individual reactions to supplements can vary, so it's best to discuss your symptoms and treatment options with a healthcare professional for personalized advice.
Based on user reviews, the time it takes to see results from the supplement varies significantly among individuals. Some users, like one who reported noticeable benefits after just 10 days of consistent use, found their headaches and nausea diminished during this time Read Review. Others have noted more gradual improvements, with general well-being increasing after prolonged use of a month or more Read Review.
However, not all experiences were positive, as a few users indicated that they encountered nausea shortly after starting the regimen, which led to discontinuation Read Review. It's worth noting that factors such as whether the supplement is taken with food or on an empty stomach can significantly affect the experience, with many advising to consume it after meals to help mitigate nausea Read Review. Thus, while some users noted quick relief, the overall timeframe for witnessing the desired effects can significantly vary depending on individual reactions to the supplement.
When it comes to finding relief from nausea, certain supplements show promise based on scientific research. Vitamin B6, also known as pyridoxine, has been specifically studied for its effects on postoperative nausea and vomiting (PONV), and the findings are encouraging. In a controlled study involving patients after gynecological surgery, those who received pyridoxine reported lower levels of nausea compared to those who were given a placebo. While these results indicate that vitamin B6 may be effective in managing nausea, further research with a more diverse patient population is necessary to confirm its efficacy across different scenarios [1].
Additionally, vitamin B6 has been evaluated for its role in alleviating nausea and vomiting during pregnancy (NVP). A comprehensive review of 18 studies suggests that pyridoxine supplementation, whether used alone or in combination with other treatments, led to significant improvements in reducing nausea in pregnant women. Notably, about 44% of the studies highlighted the effectiveness of vitamin B6 by itself, reinforcing its potential as a viable option for managing this common pregnancy symptom [4]. These findings underline the importance of considering vitamin B6 as a complementary approach for those experiencing nausea.
Based on user reviews, many individuals have reported significant improvements in their symptoms after taking the vitamin B complex. For instance, one user noted that after two months of use, their homocysteine levels dropped, which led to a successful pregnancy, suggesting a positive impact on overall health Read Review. Others have experienced a marked reduction in frequent headaches and nausea, with one user reporting that their mood also significantly improved after incorporating the supplement into their regimen Read Review. Additionally, another user mentioned that taking the product consistently helped alleviate eye fatigue and related discomfort, affirming that they feel well-suited to this brand Read Review.
However, it’s important to highlight that individual results can vary, with some reviewers experiencing side effects like nausea and bloating. While several users reported no adverse reactions and found the product effective, others did not fare as well, citing nausea and discomfort while taking the supplement Read Review. This underscores the necessity of paying attention to how one's body reacts and possibly adjusting the intake method, such as taking the capsules with food to mitigate any unpleasant symptoms Read Review.
Based on user reviews, many individuals have reported positive outcomes when integrating this supplement with other vitamins to manage nausea. One user noted that taking the supplement alongside vitamin D3+K2 and magnesium led to a significant reduction in headaches and nausea within just ten days of consistent use Read Review. Similarly, another reviewer mentioned combining it with other supplements resulted in improved symptoms related to eye fatigue and unnecessary stomach discomfort, indicating an overall compatibility with other products Read Review.
However, it's crucial to note that individual reactions can vary. Some users experienced nausea when not taking the supplement with sufficient food or when trying to increase their dosage Read Review. A few have reported adverse effects like bloating and nausea regardless of whether they followed guidance on food intake Read Review. Thus, while many report successful combinations and symptom relief, caution is advised as varying reactions may occur based on individual tolerance and intake method.
Based on recent research, Vitamin B6, also known as pyridoxine, appears to be an effective option for alleviating nausea in various contexts, including pregnancy and postoperative settings. For instance, a study highlighted that patients who received pyridoxine reported lower levels of postoperative nausea after gynecological surgeries compared to those who took a placebo [1]. Additionally, another investigation into nausea and vomiting during pregnancy found that Vitamin B6 supplementation, either alone or alongside other treatments, led to significant improvements [4].
While the exact optimal dose can vary from case to case, findings indicate that Vitamin B6 can have a positive impact on the condition. Moreover, in a specific case of an elderly cancer patient experiencing nausea due to severe thiamine deficiency, administering 100 mg of thiamine IV resulted in notable improvements [2]. This observation suggests that addressing vitamin deficiencies is crucial in managing nausea effectively, although more detailed studies are necessary to determine standardized dosing. Overall, Vitamin B Complex, especially pyridoxine, may serve as a viable option for individuals looking to cope with nausea.
7.5
Headaches relieved
I'm very pleased with the fast delivery and high-quality herbal composition. Though the capsules are slightly large, swallowing is easy. I've been taking one daily with meals alongside vitamin D3+K2 and magnesium. After 10 days, I've noticed significant benefits; my frequent headaches and nausea have diminished, my energy has increased, and my mood is excellent. I recommend it, especially for those interested in fitness or dieting.
7.5
Nausea prevented
7 people found this helpful
It helped me! A geneticist prescribed these capsules due to my increased homocysteine levels. After two months of taking these vitamins, my levels fell, and I successfully became pregnant. I recommend taking them after meals to avoid nausea.
0
Nausea increases regularly
11 people found this helpful
I felt sick while taking 1 capsule every day. I developed a red rash on the back of my hand that vanished as soon as I stopped taking it. Although it was a waste, I switched to every other day. This time, nausea appeared after consumption. Even if vitamins are water-soluble and excess should be excreted, excess fat-soluble vitamins seem to cause such symptoms, likely from folic acid. I think there's variation due to capsule size, but I've never experienced such symptoms before with supplements or medicine.
7.5
Nausea with food
1 people found this helpful
It's a great product, but taking it without enough food can cause nausea, so be sure to eat!
9
Nausea from capsules
Good composition, fast delivery, high-quality packaging. However, the capsules are a bit large but swallow easily. I've noticed the benefits since taking this alongside other supplements; I had frequent headaches and nausea, which have now diminished. My mood has improved significantly too, and I recommend it, especially for fitness enthusiasts.
7.5
Eye strain relief
4 people found this helpful
Eye fatigue can lead to a dull pain encasing my head, which extends to my neck and causes nausea. However, taking this product and avoiding use for the rest of the day has allowed my symptoms to improve the next day. If I continue taking it, I don't feel much eye fatigue, and stomach issues aren't present, suggesting it suits me well.
0
Highly bloating effect
3 people found this helpful
Not satisfied. Severe bloating; it has very high amounts, and everyone in my family experienced bloating and nausea after taking it. I recommend another brand with fewer doses.
7
Pyridoxine shows potential for PONV
Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial.
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.
Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
8
Pyridoxine reduces nausea in pregnancy
The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.
Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.
Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
9
Thiamine deficiency linked to anorexia
Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi.
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.
After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
References
Zhang Q, Ye X, Shi S, Zhou S, Ma D, et al. Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial. Anesthesiology. 2024. doi:10.1097/ALN.0000000000005354
Hayashi E, Matuura T, Takano J, Morofushi K, Toriizuka K, et al. Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi. Palliat Support Care. 2024;22:1511. doi:10.1017/S1478951524000415
Saz-Leal P, Zamorano-Domínguez L, Frías J, Guerra P, Saura-Valls M, et al. Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy. Drugs R D. 2023;23:185. doi:10.1007/s40268-023-00425-7
Jayawardena R, Majeed S, Sooriyaarachchi P, Abeywarne U, Ranaweera P. The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2023;308:1075. doi:10.1007/s00404-023-06925-w