Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Medium or Average
Based on 19 Reviews
6.3
Supplement Facts
Serving Size:  1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%

Top Medical Research Studies

We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.

Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Read More
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.

Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Read More

Most Useful Reviews

9
Nausea followed rash
11 people found this helpful
I felt unwell after taking one capsule daily, as I developed a red rash on the back of my left hand without itching. Upon ceasing the supplement, the rash cleared up. Although I was unsure of the cause, I suspect high doses of vitamins can result in such issues. I thought nausea may stem from folic acid. As the capsules are quite large, individual reactions may vary, but I recommend caution when self-prescribing.
Read More
9
No adverse reaction
2 people found this helpful
Very good! This complex delivers what it promises. I had issues with rash due to niacin when I previously purchased another product from this site. However, with this one, there were no adverse reactions. It noticeably improved my mood and even helped with hair loss. I will certainly continue using this excellent quality product!
Read More
0
Immediate rash reaction
1 people found this helpful
I had a reaction to this product 30 minutes after taking it. I experienced flushed skin, tingling, and a burning skin rash, accompanied by a headache and general malaise.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
  • All Researches
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.

Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Read More
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.

Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 19 Reviews
6.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Nausea followed rash
11 people found this helpful
I felt unwell after taking one capsule daily, as I developed a red rash on the back of my left hand without itching. Upon ceasing the supplement, the rash cleared up. Although I was unsure of the cause, I suspect high doses of vitamins can result in such issues. I thought nausea may stem from folic acid. As the capsules are quite large, individual reactions may vary, but I recommend caution when self-prescribing.
Read More
9
No adverse reaction
2 people found this helpful
Very good! This complex delivers what it promises. I had issues with rash due to niacin when I previously purchased another product from this site. However, with this one, there were no adverse reactions. It noticeably improved my mood and even helped with hair loss. I will certainly continue using this excellent quality product!
Read More
0
Immediate rash reaction
1 people found this helpful
I had a reaction to this product 30 minutes after taking it. I experienced flushed skin, tingling, and a burning skin rash, accompanied by a headache and general malaise.
Read More
0
Severe rash reaction
1 people found this helpful
After taking this supplement for the first time, I experienced terrible rashes immediately. I will not use it again.
Read More
9
Rash not noticeable
Great product! It's an excellent dosage, and my body responds well. The rash is hardly noticeable. I continue taking 2 capsules daily, although I would not recommend taking it on an empty stomach; better to take it an hour after breakfast.
Read More

Frequently Asked Questions

9
Rash healed quickly
The effect is beneficial, and the price is quite reasonable. Taking one tablet a day has shown clear effects; the rash around my mouth started to heal after a few days of use.
9
Effective for rash
Whenever I experience a rash, I take B complex, and it improves rapidly; it's very effective.
0
Severe rash reaction
1 people found this helpful
After taking this supplement for the first time, I experienced terrible rashes immediately. I will not use it again.
0
Immediate rash reaction
1 people found this helpful
I had a reaction to this product 30 minutes after taking it. I experienced flushed skin, tingling, and a burning skin rash, accompanied by a headache and general malaise.
9
B vitamins effective
1 people found this helpful
Nice complex. B vitamins offer numerous benefits, particularly for the skin; I noticed a significant decrease and even disappearance of rashes and acne. I also felt more energetic.
9
No adverse reaction
2 people found this helpful
Very good! This complex delivers what it promises. I had issues with rash due to niacin when I previously purchased another product from this site. However, with this one, there were no adverse reactions. It noticeably improved my mood and even helped with hair loss. I will certainly continue using this excellent quality product!
7.5
Improved rash condition
After some time of use, I noticed that my rash problem has significantly improved.
2
Severe niacin flush
12 people found this helpful
Beware of Niacin Flush. I develop a severe niacin flush 15 to 20 minutes after taking one capsule around lunchtime. It is less intense with food and plenty of water, but the bright redness of my skin, the heat beneath it, and the sensation of burning for a few moments should be noted. The first time I experienced this, I genuinely thought I was going to die, but it is a regular symptom.
0
Skin rash developed
1 people found this helpful
Doesn't fit. It seems that the high dosage did not suit me, as I developed a skin rash and chose to stop taking it, passing it on to my family.
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.

Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.

Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.

References

  1. Adie MA, Martes Gomez M, Yom J, Durand M, Wertheimer F, et al. Twin Premature Infants With Riboflavin and Biotin Deficiency Presenting With Refractory Lactic Acidosis, Rash, and Multiorgan Failure During Prolonged Parenteral Nutrition. J Investig Med High Impact Case Rep. 2023;11:23247096231168111. doi:10.1177/23247096231168111
  2. Nabity SA, Mponda K, Gutreuter S, Surie D, Zimba SB, et al. Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study. Lancet Glob Health. 2022;10:e705. doi:10.1016/S2214-109X(22)00096-1
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