Last update
4/9/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.2
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%
Top Medical Research Studies
9
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Read More
9
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.
Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Read More
Most Useful Reviews
0
Severe rash reaction
1 people found this helpful
After taking this supplement for the first time, I experienced terrible rashes immediately. I will not use it again.
Read More
9
Rash not noticeable
Great product! It's an excellent dosage, and my body responds well. The rash is hardly noticeable. I continue taking 2 capsules daily, although I would not recommend taking it on an empty stomach; better to take it an hour after breakfast.
Read More
9
Effective for rash
Whenever I experience a rash, I take B complex, and it improves rapidly; it's very effective.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
- All Researches
9
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Read More
9
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.
Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.2
- All Reviews
- Positive Reviews
- Negative Reviews
0
Severe rash reaction
1 people found this helpful
After taking this supplement for the first time, I experienced terrible rashes immediately. I will not use it again.
Read More
9
Rash not noticeable
Great product! It's an excellent dosage, and my body responds well. The rash is hardly noticeable. I continue taking 2 capsules daily, although I would not recommend taking it on an empty stomach; better to take it an hour after breakfast.
Read More
9
Effective for rash
Whenever I experience a rash, I take B complex, and it improves rapidly; it's very effective.
Read More
0
Negative experience
7 people found this helpful
Self Assignment Extremely Not Recommend. Frankly, I do not know how many stars to put, as I cannot ascertain the true value of this drug. I made the mistake of purchasing it myself. After taking just one capsule, I suffered an allergic reaction manifesting as a rash on my face. Additionally, my urine turned an acidic yellow. What a waste of money; no more experiments with self-prescribing vitamins for me.
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0
Unexpected rash
2 people found this helpful
I tried this vitamin, and it gave me a rash. I am uncertain whether it was due to silicon dioxide or another filler. I have previously purchased products from this brand and was quite surprised by the reaction.
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Frequently Asked Questions
9
Rash healed quickly
The effect is beneficial, and the price is quite reasonable. Taking one tablet a day has shown clear effects; the rash around my mouth started to heal after a few days of use.
9
Effective for rash
Whenever I experience a rash, I take B complex, and it improves rapidly; it's very effective.
0
Severe rash reaction
1 people found this helpful
After taking this supplement for the first time, I experienced terrible rashes immediately. I will not use it again.
7.5
Improved rash condition
After some time of use, I noticed that my rash problem has significantly improved.
0
Skin rash developed
1 people found this helpful
Doesn't fit. It seems that the high dosage did not suit me, as I developed a skin rash and chose to stop taking it, passing it on to my family.
9
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
9
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.
Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
References
- Adie MA, Martes Gomez M, Yom J, Durand M, Wertheimer F, et al. Twin Premature Infants With Riboflavin and Biotin Deficiency Presenting With Refractory Lactic Acidosis, Rash, and Multiorgan Failure During Prolonged Parenteral Nutrition. J Investig Med High Impact Case Rep. 2023;11:23247096231168111. 10.1177/23247096231168111
- Nabity SA, Mponda K, Gutreuter S, Surie D, Zimba SB, et al. Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study. Lancet Glob Health. 2022;10:e705. 10.1016/S2214-109X(22)00096-1
