Last update
3/30/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.6
USERS' SCORE
Good
Based on 9 Reviews
8
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Bromelain (from pineapple ext.) (stem)(3,000 Gelatin Digesting Units per gram)
500 mg (1,500 GDU)
†
Top Medical Research Studies
9
We examined how bromelain, a pineapple extract, helps in identifying allergies to Hymenoptera venom. By analyzing serum from 51 patients, we found that many presented cross-reactive IgE due to a carbohydrate called CCD.
Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.
Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.
Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Read More
8
We explored how bromelain, a natural extract from pineapples, influences allergic airway disease in a mouse model. Mice were sensitized and treated with bromelain or saline over several days.
Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.
However, further research is needed to confirm these effects in human subjects.
Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.
However, further research is needed to confirm these effects in human subjects.
Read More
9.5
The study looked into how plant-made influenza vaccines interact with the immune system, particularly concerning allergies. We followed 280 participants over six months, monitoring for allergic reactions and measuring specific antibodies.
While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
Read More
Most Useful Reviews
8
Surprising results
45 people found this helpful
Initially bought for digestion, yet the effects on allergies and congestion surprised me. I took Bromelain during my last pregnancy to handle severe allergies. After taking it, my nasal congestion improved remarkably. It appears to work well for allergies and sinus congestion.
Read More
9
Improved allergy symptoms
6 people found this helpful
Sure has helped my terrible allergies. I started this to minimise swelling post-operatively, and I've noticed a marked improvement in my chronic allergies. My runny nose and mouth breathing at night have significantly reduced, and I’m no longer suffering from itchy, watery eyes. I'm still taking Zyrtec and two capsules of bromelain daily, preferably on an empty stomach. Who would have thought it would be helpful? The capsules are easy to swallow as well.
Read More
9
Effective for rhinitis
3 people found this helpful
I purchased this for its ability to suppress inflammation in the body. It has been effective for my rhinitis during seasonal changes! The capsule form is convenient to ingest quickly, and it has no taste, making it easy to swallow.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.6
- All Researches
9.5
The study looked into how plant-made influenza vaccines interact with the immune system, particularly concerning allergies. We followed 280 participants over six months, monitoring for allergic reactions and measuring specific antibodies.
While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
Read More
9
We examined how bromelain, a pineapple extract, helps in identifying allergies to Hymenoptera venom. By analyzing serum from 51 patients, we found that many presented cross-reactive IgE due to a carbohydrate called CCD.
Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.
Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.
Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Read More
8
We explored how bromelain, a natural extract from pineapples, influences allergic airway disease in a mouse model. Mice were sensitized and treated with bromelain or saline over several days.
Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.
However, further research is needed to confirm these effects in human subjects.
Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.
However, further research is needed to confirm these effects in human subjects.
Read More
8
We examined how bromelain, an enzyme derived from pineapple, affects children under 11 with acute sinusitis. In our study involving 116 patients across Germany, we compared those treated with bromelain alone, standard treatments, and a mix of both.
The results revealed that the bromelain group had the quickest recovery, with symptoms lasting about 6.66 days. Interestingly, only one patient had a mild allergic reaction, which was self-limiting. Overall, bromelain appears to provide a beneficial treatment option for young children suffering from acute sinusitis.
The results revealed that the bromelain group had the quickest recovery, with symptoms lasting about 6.66 days. Interestingly, only one patient had a mild allergic reaction, which was self-limiting. Overall, bromelain appears to provide a beneficial treatment option for young children suffering from acute sinusitis.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
8
Surprising results
45 people found this helpful
Initially bought for digestion, yet the effects on allergies and congestion surprised me. I took Bromelain during my last pregnancy to handle severe allergies. After taking it, my nasal congestion improved remarkably. It appears to work well for allergies and sinus congestion.
Read More
9
Improved allergy symptoms
6 people found this helpful
Sure has helped my terrible allergies. I started this to minimise swelling post-operatively, and I've noticed a marked improvement in my chronic allergies. My runny nose and mouth breathing at night have significantly reduced, and I’m no longer suffering from itchy, watery eyes. I'm still taking Zyrtec and two capsules of bromelain daily, preferably on an empty stomach. Who would have thought it would be helpful? The capsules are easy to swallow as well.
Read More
9
Effective for rhinitis
3 people found this helpful
I purchased this for its ability to suppress inflammation in the body. It has been effective for my rhinitis during seasonal changes! The capsule form is convenient to ingest quickly, and it has no taste, making it easy to swallow.
Read More
9
Nasal allergy relief
This product is effective for improving nasal allergies!
Read More
7.5
Relieves allergies
A very good product to relieve allergies. I recommend taking it before meals to assist with digestion; it works wonderfully for me.
Read More
Frequently Asked Questions
2
No improvement noticed
I noticed improved digestion from bromelain but did not observe any results for my allergies, even though I took it without a doctor's advice.
9
Effective for rhinitis
3 people found this helpful
I purchased this for its ability to suppress inflammation in the body. It has been effective for my rhinitis during seasonal changes! The capsule form is convenient to ingest quickly, and it has no taste, making it easy to swallow.
0
Time needed for allergies
I can't say much for skin allergies as I took it along with Pipin and Vitamin C, but there was no improvement. Perhaps I simply didn’t give it enough time.
4
Allergy worsened
Consuming bromelain daily has improved my digestion, and while the quality is good, I feel my allergy symptoms have slightly advanced.
9
We examined how bromelain, a pineapple extract, helps in identifying allergies to Hymenoptera venom. By analyzing serum from 51 patients, we found that many presented cross-reactive IgE due to a carbohydrate called CCD.
Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.
Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.
Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
8
We explored how bromelain, a natural extract from pineapples, influences allergic airway disease in a mouse model. Mice were sensitized and treated with bromelain or saline over several days.
Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.
However, further research is needed to confirm these effects in human subjects.
Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.
However, further research is needed to confirm these effects in human subjects.
8
We examined how bromelain, an enzyme derived from pineapple, affects children under 11 with acute sinusitis. In our study involving 116 patients across Germany, we compared those treated with bromelain alone, standard treatments, and a mix of both.
The results revealed that the bromelain group had the quickest recovery, with symptoms lasting about 6.66 days. Interestingly, only one patient had a mild allergic reaction, which was self-limiting. Overall, bromelain appears to provide a beneficial treatment option for young children suffering from acute sinusitis.
The results revealed that the bromelain group had the quickest recovery, with symptoms lasting about 6.66 days. Interestingly, only one patient had a mild allergic reaction, which was self-limiting. Overall, bromelain appears to provide a beneficial treatment option for young children suffering from acute sinusitis.
References
- Abram DM, Fernandes LGR, Perez-Riverol A, Regina Brochetto-Braga M, Zollner RL. Cross-Reactive Carbohydrate Determinant in , and Venoms: Identification of Allergic Sensitization and Cross-Reactivity. Toxins (Basel). 2020;12. 10.3390/toxins12100649
- Ward BJ, Landry N, Trépanier S, Mercier G, Dargis M, et al. Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines. Vaccine. 2014;32:6098. 10.1016/j.vaccine.2014.08.079
- Secor ER, Carson WF, Cloutier MM, Guernsey LA, Schramm CM, et al. Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease. Cell Immunol. 2005;237:68. PubMed
- Braun JM, Schneider B, Beuth HJ. Therapeutic use, efficiency and safety of the proteolytic pineapple enzyme Bromelain-POS in children with acute sinusitis in Germany. In Vivo. 2005;19:417. PubMed
Data last updated:
