A year and a half later I confirm again that it works for me like magic. I want to emphasize that I was not asked for this review, nor getting any free product. Here is the story. After finishing the first bottle, for the reason I don't remember, I decided to buy a different brand of glucosamine. It was probably also working for my joints because I didn't experience any pain. But it was making me feel dizzy. I'd stop for a while and start again and every time I felt dizzy. So I stopped it all together. A few months later my knees started hurting again and I remembered my own praise for Doctor's Best glucosamine. Now I am back on track: one capsule a day (maybe it is enough for highly sensitive people?) and the knee pain is gone from the day one. Amazing! I have to mention that when I started Doctor's Best almost two years ago I also experienced dizziness at first (just didn't know it could be related) but it improved within a few days. When I restarted this time, there were no side-effects at all. And you know what? I think it works for my dog too. A few months ago our 9 year-old Yorkie started hesitating and sometimes completely refusing to jump up just a few steps on the stairs. The vet didn't see anything wrong with her joints. We decided to start adding a tiny bit of glucosamine in her food once a day and see if that helps. Within a week she started jumping stairs again without hesitation. Keep in mind that our dog is also on a perfect anti-inflammatory diet: all homemade, mostly organic, no junk food at all. ------ I rarely write reviews for the supplements because it's hard to determine whether this particular supplement is actually working. This time something amazing happened, so I want to share it; maybe it will help someone else. For a few weeks I'd been feeling mild but persistent pain in my both knees that did not allow me to walk stairs freely like I used to. When I bought this Glucosamine Chondroitin MSM I was hoping that within a few weeks of taking it my knees will start feeling better. The unexpected magic happened! I took just one capsule in the evening and I woke up next morning without any discomfort in my knees! I know... can it be really so potent?! Maybe it's just a coincidence but it also could be a synergistic effect and the final piece of the puzzle is in its place. In addition to my diligent anti-inflammatory diet, I take Fish Oil, Turmeric and Boswellia for quite a while now. It seems to be working for me pretty well because most of the time I don't even feel any signs of Arthritis that was haunting me many years ago. Now I added Glucosamine Chondroitin MSM and all my joints are happy. I still take just one, sometimes two, capsules a day instead of recommended 4. It works! Try it. Highly recommend

If you are new to MSM, you should read THE MIRACLE OF MSM by Stanley Jacob, MD. He explains MSM and how it works in layman's terms. I've dealt with joint pain AND sciatic pain that was so painful I was wondering if I had cancer in both my legs! The following protocol/regimen is what has brought me to a place of being, literally, 99% pain free. It is my opinion (personal experience) that the combination of the hyaluronic acid and collagen II along with Doctor's Best MSM has just about cured me. This is by Russell Blaylock, MD Special Supplements to Repair Joints * *Hyaluronic acid The joint contains cartilage composed of complex glycosaminoglycans, which aid in joint health. One product that supplies this vital substance is hyaluronic acid. This is a component of connective tissue whose function is to cushion and lubricate. Some products contain the larger molecular form, which is not absorbed. Pure Encapsulation Company makes a product under this name. It has a lower molecular weight and is well absorbed. The dose is three capsules twice a day with or between meals. You can get Pure Encapsulation products at [...] * *MSM Also called methyl sulfonyl methane, MSM is a natural form of sulfur found in living organisms. Its main benefits are a reduction of inflammation and the ability to penetrate many tissues, including joints. Recent studies have confirmed its safety, even when used in large doses over prolonged periods of time. The dose is 500 mg. to 1,000 mg. two to three times a day with meals. It is widely available. * *Collagen type II This is a major component in cartilage, and supplementation has demonstrated benefits in reducing pain and improving joint function. The dose is three capsules twice a day on an empty stomach. It is important that you get a brand made from chicken rather than bovine. You can get this from [...] * Tart cherry extract A number of studies have shown that concentrated extracts of tart cherries improve joint function and reduce pain and swelling. You can also get this fromJuly 2006 The Blaylock Wellness Report Page 5 [...]. The dose is one to two capsules a day. * Triple stack This is a special compounded supplement containing full therapeutic doses of MSM, glucosamine, and curcumin. The dose is one capsule three times a day. It should be taken with meals. The best results are seen within three weeks. It can only be found at Specialty Pharmacy [...] Special Supplements to Reduce Inflammation Below I will discuss special plant extracts and vitamins that can reduce inflammation and free radicals within the joint. * *Curcumin This is one of the most powerful natural anti- inflammatory substances known. Its effects are comparable to steroids, without the harmful effects. All inflammatory Arthritis problems arise from the activation of a special inflammation signal molecule in cartilage cells called NFkappaB, or NFKB. Curcumin powerfully inhibits this cell signal and also suppresses the destructive enzymes mentioned above (MMPs and collagenase). Curcumin is best absorbed when dissolved in an oil. I would recommend either extra virgin olive oil or fish oil. Fish oil has a significant anti-inflammatory effect all its own, so I would recommend over olive oil. The dose is 250 mg. of curcumin powder mixed with a half-tablespoon of fish oil. Mix well. Take this three times a day with meals. * *Quercetin This is also a powerful anti-inflammatory and antioxidant. When combined with curcumin, you get a powerful anti-inflammatory effect because they each act on different inflammatory biochemical pathways. It also suppresses the destructive enzymes I spoke about (MMPs and collagenase). Mix 250 mg. of quercetin into oil with the curcumin and take that three times a day. * *Borage oil Borage oil contains a high concentration of gamma-linolenic acid, which has significant anti- inflammatory properties. It also moistens mucous membranes and the skin. You can add this to the mix above. It will come in a gelatin capsule, but don't eat that -- just stick a pin into it and squeeze 1,000 mg. into the mentioned mix twice a day. Keep both the fish oil and borage oil in the refrigerator. * *Natural vitamin E (Unique-E) Vitamin E, in natural form, has significant anti- inflammatory effects. The dose is 1,000 IU a day. Unique-E is the brand I recommend. * *Buffered vitamin C (calcium/magnesium ascorbate) Vitamin C is not only a powerful antioxidant and anti-inflammatory, but it also strengthens the tissues and the ligaments surrounding the joint. * *Vitamin/mineral supplement A recent study found that selenium was significantly depleted in the joints of people with Arthritis, while copper levels increased. High iron levels were found in the damaged joints of osteoarthritis sufferers. Iron is a powerful generator of inflammation and free radicals. A well-balanced supplement such as Extend Core [...]will deliver all the essential vitamins and minerals. * *Magnesium citrate or citrate/malate Magnesium supplementation has been shown to reduce inflammation, while a deficiency increases it. It not only slashes free radicals but blocks the release of inflammatory cytokines as well. The dose is two capsules twice a day between meals. A survey found that a dearth of magnesium is one of the most common mineral deficiencies seen, with 75% of the population lacking it. Chronic illness and many medications worsen magnesium loss. * Stinging nettle extract This plant extract has been shown to have powerful anti-inflammatory properties. Recent studies have found it to be very protective of the brain as well. It is often included in natural supplements used to treat chronic prostate problems for the same reason. But taking too much can produce a mucous-like diarrhea. I would limit intake to two capsules a day with meals. These are the basic steps you will need to follow for good health. I have placed an asterisk beside the most important supplements. The closer you follow these steps the more likely you will attain success. It is important to know that curcumin and quercetin can cause your blood sugar to drop slightly. While this is beneficial to those with diabetes, it can be a problem if you have reactive hypoglycemia. For this reason, always take it with a meal

I like these, although it's hard to tell how well any supplement works. My joint pain has not come back since I switched to this brand, so I'm giving this my 5 Star rating. Before using Glucosamine/Chondroitin/MSM supplements, I had severe joint pain in my shoulders, and this combination absolutely worked to relieve it! IMHO always look for a 1500/1200/1000 mixture and avoid "proprietary blends" at all cost! Propriatary blends means they don't want you to know how much (or how little) and/or what compounds they put into their crap. I used to get WalM***'s brand but I had a hard time finding it and switched to these. I like these a lot and it has the same blend, but in a capsule instead of a pill, which I find easier to swallow

I've been having some knee issues that have come and gone since 2021 after a very long hiking trip with improper shoes. I had to use my knees quite a bit to brace myself and ended up aggravating the Meniscus. Recently it was throbbing again and I've some cracking in my knees so I wanted to see if this would be a good supplement to assist with my pain but also general joint maintenance. I am a bit confused because after only 4 days my pain has reduced significantly and the knee seems to be healing much faster. The research says it could take several weeks but I don't know if I've ever experienced such a fast response to a supplement. I would definitely recommend this to anyone experiencing joint pain

I've had trouble with my knees since I was a kid. As a 40-year old, the condition is sometimes painful, especially when working out using resistance training. I regularly walk up and down a set of stairs at work, and my knees often ache throughout the climb. About 2 weeks after taking this product regularly, as directed on the bottle, I noticed my knees no longer ached when taking the stairs. I was really amazed. When I would do body weight squats in the past - literally just bending my knees and lowering my body straight down until my rear was parallel to the floor - my knees would kill me going down and coming up. I can actually do that now without pain since I've been taking this GC with MSM (I've been taking it for about a month now). This is a huge deal for me, and I'm thankful to have that range of motion, sans the pain, back. I don't claim this is a miracle product that completely healed my knees though. When I do weighted leg press or lunges at the gym, I do still experience pain in my knees. I'm not sure any medicine is going to help with that. But, I can certainly attest to the efficacy of this product for helping with joint pain associated with day-to-day living. If you've got joint pain issues, I highly recommend you try this and give it about a month. It'll work; just don't expect a miracle from it

This is a great product. I have Arthritis, stenosis and degeneration in my lower back and the pain is intense. I tried this product and it helped and I was pleasantly surprised. I decided to try a similar product and that's when I realized just how much Doctors Best really made a difference. I will not switch again. There is nothing that takes my pain completely away, but this has helped me more than any other product I've tried. I would definitely recommend this product

Let me start by saying, nobody paid me to write this, and I have no incentive to write a positive review, other than the fact that this Glucosamine/Chondrointon supplement works WAY better than anything else I've tried. I'm 60, suffering from many injuries from car crashes, a torn and partially removed medial meniscus, and 20 years of riding/training horses and the wear & tear resulting from that, so I have significant pain in both knees and lower back. For many years I used the Gluc/Chon supplement from CostCo, then switched to Dr's Best after reading Amazon reviews. I didn't really realize how well it really worked until I recently ran out on the day I went to Costco…bought that product again, and within one week, my knees started aching again really bad. It's tough, because I golf at least twice a week, and I'm a walker, so knee pain is my enemy on the course. After three weeks on the bad supplement, I switched back to Dr's Best and the pain started to subside again after about two weeks. I will NEVER buy anything else but Dr's Best…this stuff really works well for me

This is the only brand I have tried so far, but it has been extremely effective in relieving joint pain and reducing the audible cracking and crunching in my knees when ascending stairs. I have also noticed a decided reduction in daily knee pain, and in pain after workouts. I was a bit concerned about placebo effects. To do a "blind" test, I have been giving two of these twice daily to my 13 year old lab/greyhound mix with really bad hip and knee pain. I am quite certain her mobility is much better, especially going up and down stairs and getting up from a sitting or lying position. She had lost significant muscle mass this past winter due to age and lack of exercise due to the obvious severe pain. Loss of muscle coupled with the pain had an obvious negative impact on all of those movements. I added the glucosamine, but haven't yet increased activity to build additional muscle, and can still see a marked improvement in her movement and signs of reduction in pain. As the weather improves, and as the glucosamine continues to work, we will be able to increase activity and build some muscle back. Seeing this affect on her, I am quite certain the product is effective on me as well. Since I don't know how this brand compares to others, and since I don't know of anyone else who has tried glucosamine, I believe this particular product to be extremely effective for me (and my dog). I would recommend this product to friends and family

I am a competitive volleyball player in my late 20s and I've been suffering from chronic knee pain/patellofemoral syndrome/jumper's knee from repetitive jumping and landing for the last 8 years. After games or competition my knees would be sore for the next couple of days and it was painful to sit with my knees bent for more than an hour. I've tried to patellar knee straps and done some muscle balance work in the gym. None of those were as effective in pain reduction as taking these glucosamine/chondroitin/MSM capsules. Like numerous other people I was skeptical about the benefits of glucosamine/chondroitin/MSM but I finally decided to try it upon the recommendation of my nurse practitioner who takes it herself. I am so glad I took her suggestion! Instead of taking two capsules TWICE daily, I only take two capsules daily. I feel I am relatively young so I don't require the full benefits as would someone who is older. Now after volleyball my knees feel fine - no pain nor soreness! I couldn't believe it! I no longer have to rely on ibuprofen which is detrimental to liver health with chronic use. Others are right when they say you need to take these supplements daily because I've missed some days and my knees went back to being sore after playing volleyball. Overall I am very satisfied with the Doctor's Best brand of glucosamine/chondroitin/MSM and will be going back to it when my supply runs out. Great for active young athletes like myself who are looking to eliminate knee joint pain/patellofemoral syndrome/jumper's knees

Have been using the product for just 1 week. I do see my joints pain reducing.. Feel like its working something on my Knee Joints. Am over-weight around 106 Kgs. Trying to increase my Physical activity by Walking and Jogging. Initial joggin actually got me into Knee joint pain.. This product somehow seems to have worked within a week. While using this product I was continuing walking. But i see overall reduction in Joint isues esp on my neck, elbows and Knee. I started with One capsule a day.. So far so good. Am happy with this product