Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Moderately Good
Based on 21 Reviews
7.1
Supplement Facts
Serving Size:  4 capsules
Amount Per Serving
%DV
Chloride (from glucosamine hydrochloride potassium sulfate)
170 mg 
7%
Sodium (from chondroitin sulfate sodium)
120 mg
5%
Potassium (from glucosamine hydrochloride potassium sulfate)
190 mg 
4%
GlucosamineHydrochloride Potassium Sulfate
1500 mg
†
Chondroitin sulfate Sodium
1200 mg
†
MSM (Methylsulfonylmethane)(OptiMSM®)
1000 mg
†

Top Medical Research Studies

8
MSM linked to lower migraine impact
We dived into how adherence to acute migraine medications influences migraine severity and patient satisfaction. Over three months, participants diligently recorded their migraine experiences in daily diaries.

With 337 adults participating, the findings showed that those using migraine-specific medication (MSM), especially when pain was milder, reported the best outcomes. This included less daily disability and greater satisfaction with their medication.

Our results suggest that starting treatment with MSM may lead to a better quality of life for migraine sufferers.
Read More
9
Erenumab reduces migraine medication use
We explored how erenumab impacts the use of acute headache medication, especially migraine-specific medications (MSM). The study analyzed data from two major clinical trials involving patients with episodic migraine (EM) and chronic migraine (CM). Participants received either erenumab or placebo over a set period, allowing us to compare medication usage accurately.

Our findings indicate that treatment with erenumab led to a significant decrease in the number of days patients used acute headache medications, particularly in those relying on MSM. This reduction was observed in both episodic and chronic migraine patients, suggesting that erenumab not only helps manage migraines but may also help mitigate the need for additional acute treatment.

Overall, these results highlight the potential benefits of erenumab in addressing not just the frequency of migraines but also reducing dependence on medications traditionally used for acute migraine relief.
Read More

Most Useful Reviews

9
Headaches are gone
5 people found this helpful
I have intervertebral hernia and initially didn't observe much difference after taking this. However, once I began combining it with collagen, I felt the benefits. Remarkably, my headaches have disappeared as well, so I recommend taking collagen alongside this product for better results.
Read More
10
Headaches stopped
1 people found this helpful
After a month of taking this product, I found that my headaches stopped completely. I am uncertain whether this is directly linked to MSN, but it was a very pleasant bonus.
Read More
9
Effective for mother
I purchased this for my mother, and she reported that it was effective against her knee headaches.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
  • All Researches
9
Erenumab reduces migraine medication use
We explored how erenumab impacts the use of acute headache medication, especially migraine-specific medications (MSM). The study analyzed data from two major clinical trials involving patients with episodic migraine (EM) and chronic migraine (CM). Participants received either erenumab or placebo over a set period, allowing us to compare medication usage accurately.

Our findings indicate that treatment with erenumab led to a significant decrease in the number of days patients used acute headache medications, particularly in those relying on MSM. This reduction was observed in both episodic and chronic migraine patients, suggesting that erenumab not only helps manage migraines but may also help mitigate the need for additional acute treatment.

Overall, these results highlight the potential benefits of erenumab in addressing not just the frequency of migraines but also reducing dependence on medications traditionally used for acute migraine relief.
Read More
8
MSM linked to lower migraine impact
We dived into how adherence to acute migraine medications influences migraine severity and patient satisfaction. Over three months, participants diligently recorded their migraine experiences in daily diaries.

With 337 adults participating, the findings showed that those using migraine-specific medication (MSM), especially when pain was milder, reported the best outcomes. This included less daily disability and greater satisfaction with their medication.

Our results suggest that starting treatment with MSM may lead to a better quality of life for migraine sufferers.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 21 Reviews
7.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Headaches are gone
5 people found this helpful
I have intervertebral hernia and initially didn't observe much difference after taking this. However, once I began combining it with collagen, I felt the benefits. Remarkably, my headaches have disappeared as well, so I recommend taking collagen alongside this product for better results.
Read More
10
Headaches stopped
1 people found this helpful
After a month of taking this product, I found that my headaches stopped completely. I am uncertain whether this is directly linked to MSN, but it was a very pleasant bonus.
Read More
9
Effective for mother
I purchased this for my mother, and she reported that it was effective against her knee headaches.
Read More
9
Alleviated pain
I bought the capsules for my mother. They are relatively large but cost-effective. After about a month of use, my mother's knee headaches have alleviated, and she experiences no pain!
Read More
9
Headache disappeared
My knee headache disappeared after eating.
Read More

Frequently Asked Questions

7.5
Improved knee pain
After a few days of use, I noticed an improvement in my knee headaches; the dull pain has subsided significantly.
10
Headaches stopped
1 people found this helpful
After a month of taking this product, I found that my headaches stopped completely. I am uncertain whether this is directly linked to MSN, but it was a very pleasant bonus.
0
Severe headache reaction
5 people found this helpful
I took this complex for connective tissue and joints, but sadly, it didn’t work out for me. While I have no complaints about the product's quality, I did experience a severe headache after taking it, possibly due to the sulfur in the composition, unlike similar products from other brands. Unfortunately, I cannot recommend it. I hope my review helps you. Wishing you and your loved ones good health!
9
Alleviated pain
I bought the capsules for my mother. They are relatively large but cost-effective. After about a month of use, my mother's knee headaches have alleviated, and she experiences no pain!
9
Headaches are gone
5 people found this helpful
I have intervertebral hernia and initially didn't observe much difference after taking this. However, once I began combining it with collagen, I felt the benefits. Remarkably, my headaches have disappeared as well, so I recommend taking collagen alongside this product for better results.
0
Triggers headaches
I strangely get a headache if I eat this; I can't consume it. I've searched everywhere but can't figure out why.
0
Bad experience
This product isn't for everyone. It gave me a dreadful headache and stomach issues.
9
Erenumab reduces migraine medication use
We explored how erenumab impacts the use of acute headache medication, especially migraine-specific medications (MSM). The study analyzed data from two major clinical trials involving patients with episodic migraine (EM) and chronic migraine (CM). Participants received either erenumab or placebo over a set period, allowing us to compare medication usage accurately.

Our findings indicate that treatment with erenumab led to a significant decrease in the number of days patients used acute headache medications, particularly in those relying on MSM. This reduction was observed in both episodic and chronic migraine patients, suggesting that erenumab not only helps manage migraines but may also help mitigate the need for additional acute treatment.

Overall, these results highlight the potential benefits of erenumab in addressing not just the frequency of migraines but also reducing dependence on medications traditionally used for acute migraine relief.
8
MSM linked to lower migraine impact
We dived into how adherence to acute migraine medications influences migraine severity and patient satisfaction. Over three months, participants diligently recorded their migraine experiences in daily diaries.

With 337 adults participating, the findings showed that those using migraine-specific medication (MSM), especially when pain was milder, reported the best outcomes. This included less daily disability and greater satisfaction with their medication.

Our results suggest that starting treatment with MSM may lead to a better quality of life for migraine sufferers.

References

  1. Tepper SJ, Ashina M, Reuter U, Hallström Y, Broessner G, et al. Reduction in acute migraine-specific and non-specific medication use in patients treated with erenumab: post-hoc analyses of episodic and chronic migraine clinical trials. J Headache Pain. 2021;22:81. 10.1186/s10194-021-01292-w
  2. Seng EK, Robbins MS, Nicholson RA. Acute migraine medication adherence, migraine disability and patient satisfaction: A naturalistic daily diary study. Cephalalgia. 2017;37:955. 10.1177/0333102416663459
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