Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Medium or Average
Based on 13 Reviews
6.9
Supplement Facts
Serving Size: 2 Veggie Capsules
Amount Per Serving
%DV
BioCell Collagen®(from chicken sternal cartilage) providing minimum:Hydrolyzed Collagen Type IIChondroitin SulfateHyaluronic Acid
1000 mg600 mg200 mg100 mg
††††

Top Medical Research Studies

9
Hyaluronic acid gel shows promise
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
Read More
8
Hyaluronic acid enhances skin regeneration
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.

We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.

This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
Read More
8
COVID-19 exacerbates dermatitis herpetiformis
We observed a compelling case where a 74-year-old woman experienced a severe flare of dermatitis herpetiformis, a rare autoimmune skin condition, following a COVID-19 infection.

Initially, she presented with blisters and oral ulcers. After treatment that included hyaluronic acid mouthwash, her oral lesions showed remarkable improvement over four weeks.

Unfortunately, after contracting COVID-19, she had another flare-up, but again, her symptoms resolved after a month of treatment. This highlights the impact of COVID-19 on existing autoimmune conditions.
Read More

Most Useful Reviews

9
Rash eventually cleared
2 people found this helpful
Initially, rashes appeared on my skin when I started taking it, but I continued nonetheless. After a month, the skin changed and the rash disappeared. My complexion now looks healthy and even. I'm pleased with the result and have ordered more.
Read More
0
Developed severe rash
1 people found this helpful
I developed a rash, a cluster of red, scaly bumps around my wrists and the back of my elbow, as a result of this supplement.
Read More
2
Noticeable rash observed
6 people found this helpful
To each their own; I did not like the product as I unfortunately developed a noticeable rash with this dosage. However, my mother has already finished her third jar! Even her beautician has noticed a clear effect from taking it. Her facial skin has become more radiant and puffy eyes less pronounced. An important point to note is that while taking this drug, one must drink a considerable amount of water; otherwise, it will not be effective.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
  • All Researches
9
Hyaluronic acid gel shows promise
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
Read More
9
Effective treatment for atopic dermatitis
We explored the impact of MAS063DP cream on mild to moderate atopic dermatitis in a clinical study involving 218 adults. Patients were randomly assigned to use either the MAS063DP cream or a placebo for 50 days, applying it three times daily to affected skin areas. Our results showed that MAS063DP was significantly more effective in reducing symptoms compared to the vehicle, with lower rates of rash reported in the treatment group. This indicates that MAS063DP cream is a promising option for managing atopic dermatitis.
Read More
8
Hyaluronic acid enhances skin regeneration
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.

We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.

This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
Read More
8
COVID-19 exacerbates dermatitis herpetiformis
We observed a compelling case where a 74-year-old woman experienced a severe flare of dermatitis herpetiformis, a rare autoimmune skin condition, following a COVID-19 infection.

Initially, she presented with blisters and oral ulcers. After treatment that included hyaluronic acid mouthwash, her oral lesions showed remarkable improvement over four weeks.

Unfortunately, after contracting COVID-19, she had another flare-up, but again, her symptoms resolved after a month of treatment. This highlights the impact of COVID-19 on existing autoimmune conditions.
Read More
8
Hyaluronic acid treatments reduce wrinkles
We explored the effectiveness of two hyaluronic acid fillers in treating superficial wrinkles around the mouth. In a double-blind study involving 48 patients, we compared small-particle hyaluronic acid with lidocaine to cohesive polydensified matrix hyaluronic acid.

Both treatments reduced wrinkling, with notable results maintained for 180 days. However, the small-particle approach showed superior effectiveness as rated by both patients and investigators after the treatment period. While both products had similar safety profiles, adverse reactions included some rash among patients using cohesive matrix fillers.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 13 Reviews
6.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Rash eventually cleared
2 people found this helpful
Initially, rashes appeared on my skin when I started taking it, but I continued nonetheless. After a month, the skin changed and the rash disappeared. My complexion now looks healthy and even. I'm pleased with the result and have ordered more.
Read More
0
Developed severe rash
1 people found this helpful
I developed a rash, a cluster of red, scaly bumps around my wrists and the back of my elbow, as a result of this supplement.
Read More
2
Noticeable rash observed
6 people found this helpful
To each their own; I did not like the product as I unfortunately developed a noticeable rash with this dosage. However, my mother has already finished her third jar! Even her beautician has noticed a clear effect from taking it. Her facial skin has become more radiant and puffy eyes less pronounced. An important point to note is that while taking this drug, one must drink a considerable amount of water; otherwise, it will not be effective.
Read More
7.5
Winter rash prevented
1 people found this helpful
I really liked the effect of these capsules; they made my skin smoother and more radiant. Normally, in winter, I get skin rashes from the cold, but taking this drug has prevented that. My pores are less noticeable, and my skin tone is even. I was apprehensive about puffiness, but that was not an issue. I plan to continue taking it.
Read More
8
Rash significantly reduced
I used to eat nutrient-rich food. This product has been beneficial; I've experienced a notable reduction in rashes and excess sebum, thanks to L-Cysteine.
Read More

Frequently Asked Questions

7.5
No rashes after use
I bought this product based on word of mouth. After a week of not taking it, my skin felt smooth and moist. After two weeks, I noticed no rashes on my forehead and chin, unlike before.
6
Rash remained prevalent
1 people found this helpful
What are these supplements! I find myself needing to buy two bottles each month. The effect is felt in about 1-2 weeks. I’ve been using CoQ10; my skin rash remains quite prevalent despite the improvement in acne. If this drug does not yield substantial results, I might explore other options.
9
Rash eventually cleared
2 people found this helpful
Initially, rashes appeared on my skin when I started taking it, but I continued nonetheless. After a month, the skin changed and the rash disappeared. My complexion now looks healthy and even. I'm pleased with the result and have ordered more.
7.5
Winter rash prevented
1 people found this helpful
I really liked the effect of these capsules; they made my skin smoother and more radiant. Normally, in winter, I get skin rashes from the cold, but taking this drug has prevented that. My pores are less noticeable, and my skin tone is even. I was apprehensive about puffiness, but that was not an issue. I plan to continue taking it.
7.5
Reduced rash
I believe this aids the skin, and I also feel it reduces rashes, making my skin smoother.
7.5
Softer skin
After taking Collagen types 1 and 3 with Peptan for a month, I noticed no changes. My lips were excessively dry. After a month’s break, I resumed taking it and observed significant skin improvement; it became softer and more hydrated, with fewer rashes. Whenever a bump appeared, it healed more quickly, and my lips remained soft and moist. I took it after meals to aid absorption.
2
Noticeable rash observed
6 people found this helpful
To each their own; I did not like the product as I unfortunately developed a noticeable rash with this dosage. However, my mother has already finished her third jar! Even her beautician has noticed a clear effect from taking it. Her facial skin has become more radiant and puffy eyes less pronounced. An important point to note is that while taking this drug, one must drink a considerable amount of water; otherwise, it will not be effective.
2
Rashes appeared persistently
This hyaluronic acid supplement requires plenty of water; otherwise, your skin can dry out. I wasn't entirely pleased with the effect as I experienced more rashes when taking it.
8
Hyaluronic acid enhances skin regeneration
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.

We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.

This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
9
Hyaluronic acid gel shows promise
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
8
Hyaluronic acid treatments reduce wrinkles
We explored the effectiveness of two hyaluronic acid fillers in treating superficial wrinkles around the mouth. In a double-blind study involving 48 patients, we compared small-particle hyaluronic acid with lidocaine to cohesive polydensified matrix hyaluronic acid.

Both treatments reduced wrinkling, with notable results maintained for 180 days. However, the small-particle approach showed superior effectiveness as rated by both patients and investigators after the treatment period. While both products had similar safety profiles, adverse reactions included some rash among patients using cohesive matrix fillers.
9
Effective treatment for atopic dermatitis
We explored the impact of MAS063DP cream on mild to moderate atopic dermatitis in a clinical study involving 218 adults. Patients were randomly assigned to use either the MAS063DP cream or a placebo for 50 days, applying it three times daily to affected skin areas. Our results showed that MAS063DP was significantly more effective in reducing symptoms compared to the vehicle, with lower rates of rash reported in the treatment group. This indicates that MAS063DP cream is a promising option for managing atopic dermatitis.

References

  1. Miatmoko A, Dewangga SS, Handoko KK, Legowo D, Purwantari KE, et al. Transfersomal serum loading amniotic mesenchymal stem cells metabolite products with hyaluronic acid addition for skin regeneration in UV aging-induced mice. Int J Pharm. 2024;667:124950. 10.1016/j.ijpharm.2024.124950
  2. Shafuria A, Sufiawati I, Usman HA. A Rare Case of COVID-19-Induced Acute Exacerbation of Oral Dermatitis Herpetiformis in a Geriatric Patient. Int Med Case Rep J. 2023;16:129. 10.2147/IMCRJ.S401775
  3. Polacco MA, Singleton AE, Luu T, Maas CS. A Randomized, Blinded, Prospective Clinical Study Comparing Small-Particle Versus Cohesive Polydensified Matrix Hyaluronic Acid Fillers for the Treatment of Perioral Rhytids. Aesthet Surg J. 2021;41:NP493. 10.1093/asj/sjaa161
  4. Morali G, Polatti F, Metelitsa EN, Mascarucci P, Magnani P, et al. Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy. Arzneimittelforschung. 2006;56:230.
  5. Abramovits W, Boguniewicz M. A multicenter, randomized, vehicle-controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults. J Drugs Dermatol. 2006;5:236.
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