Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy.
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
Read More
8
Hyaluronic acid enhances skin regeneration
Transfersomal serum loading amniotic mesenchymal stem cells metabolite products with hyaluronic acid addition for skin regeneration in UV aging-induced mice.
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.
We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.
This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
Read More
8
COVID-19 exacerbates dermatitis herpetiformis
A Rare Case of COVID-19-Induced Acute Exacerbation of Oral Dermatitis Herpetiformis in a Geriatric Patient.
We observed a compelling case where a 74-year-old woman experienced a severe flare of dermatitis herpetiformis, a rare autoimmune skin condition, following a COVID-19 infection.
Initially, she presented with blisters and oral ulcers. After treatment that included hyaluronic acid mouthwash, her oral lesions showed remarkable improvement over four weeks.
Unfortunately, after contracting COVID-19, she had another flare-up, but again, her symptoms resolved after a month of treatment. This highlights the impact of COVID-19 on existing autoimmune conditions.
Read More
Most Useful Reviews
9
Rash eventually cleared
2 people found this helpful
Initially, rashes appeared on my skin when I started taking it, but I continued nonetheless. After a month, the skin changed and the rash disappeared. My complexion now looks healthy and even. I'm pleased with the result and have ordered more.
Read More
0
Developed severe rash
1 people found this helpful
I developed a rash, a cluster of red, scaly bumps around my wrists and the back of my elbow, as a result of this supplement.
Read More
2
Noticeable rash observed
6 people found this helpful
To each their own; I did not like the product as I unfortunately developed a noticeable rash with this dosage. However, my mother has already finished her third jar! Even her beautician has noticed a clear effect from taking it. Her facial skin has become more radiant and puffy eyes less pronounced. An important point to note is that while taking this drug, one must drink a considerable amount of water; otherwise, it will not be effective.
Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy.
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
Read More
9
Effective treatment for atopic dermatitis
A multicenter, randomized, vehicle-controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults.
We explored the impact of MAS063DP cream on mild to moderate atopic dermatitis in a clinical study involving 218 adults. Patients were randomly assigned to use either the MAS063DP cream or a placebo for 50 days, applying it three times daily to affected skin areas. Our results showed that MAS063DP was significantly more effective in reducing symptoms compared to the vehicle, with lower rates of rash reported in the treatment group. This indicates that MAS063DP cream is a promising option for managing atopic dermatitis.
Read More
8
Hyaluronic acid enhances skin regeneration
Transfersomal serum loading amniotic mesenchymal stem cells metabolite products with hyaluronic acid addition for skin regeneration in UV aging-induced mice.
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.
We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.
This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
Read More
8
COVID-19 exacerbates dermatitis herpetiformis
A Rare Case of COVID-19-Induced Acute Exacerbation of Oral Dermatitis Herpetiformis in a Geriatric Patient.
We observed a compelling case where a 74-year-old woman experienced a severe flare of dermatitis herpetiformis, a rare autoimmune skin condition, following a COVID-19 infection.
Initially, she presented with blisters and oral ulcers. After treatment that included hyaluronic acid mouthwash, her oral lesions showed remarkable improvement over four weeks.
Unfortunately, after contracting COVID-19, she had another flare-up, but again, her symptoms resolved after a month of treatment. This highlights the impact of COVID-19 on existing autoimmune conditions.
Read More
8
Hyaluronic acid treatments reduce wrinkles
A Randomized, Blinded, Prospective Clinical Study Comparing Small-Particle Versus Cohesive Polydensified Matrix Hyaluronic Acid Fillers for the Treatment of Perioral Rhytids.
We explored the effectiveness of two hyaluronic acid fillers in treating superficial wrinkles around the mouth. In a double-blind study involving 48 patients, we compared small-particle hyaluronic acid with lidocaine to cohesive polydensified matrix hyaluronic acid.
Both treatments reduced wrinkling, with notable results maintained for 180 days. However, the small-particle approach showed superior effectiveness as rated by both patients and investigators after the treatment period. While both products had similar safety profiles, adverse reactions included some rash among patients using cohesive matrix fillers.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 13 Reviews
6.9
All Reviews
Positive Reviews
Negative Reviews
9
Rash eventually cleared
2 people found this helpful
Initially, rashes appeared on my skin when I started taking it, but I continued nonetheless. After a month, the skin changed and the rash disappeared. My complexion now looks healthy and even. I'm pleased with the result and have ordered more.
Read More
0
Developed severe rash
1 people found this helpful
I developed a rash, a cluster of red, scaly bumps around my wrists and the back of my elbow, as a result of this supplement.
Read More
2
Noticeable rash observed
6 people found this helpful
To each their own; I did not like the product as I unfortunately developed a noticeable rash with this dosage. However, my mother has already finished her third jar! Even her beautician has noticed a clear effect from taking it. Her facial skin has become more radiant and puffy eyes less pronounced. An important point to note is that while taking this drug, one must drink a considerable amount of water; otherwise, it will not be effective.
Read More
7.5
Winter rash prevented
1 people found this helpful
I really liked the effect of these capsules; they made my skin smoother and more radiant. Normally, in winter, I get skin rashes from the cold, but taking this drug has prevented that. My pores are less noticeable, and my skin tone is even. I was apprehensive about puffiness, but that was not an issue. I plan to continue taking it.
Read More
8
Rash significantly reduced
I used to eat nutrient-rich food. This product has been beneficial; I've experienced a notable reduction in rashes and excess sebum, thanks to L-Cysteine.
A rash is a noticeable change in the texture or color of the skin that can manifest in various ways, including redness, swelling, itching, or blistering. Rashes can result from a wide range of causes, such as allergies, irritants, infections, or skin conditions like eczema or psoriasis. While some rashes may be mild and resolve on their own, others might require medical attention, particularly if they are persistent, widespread, or accompanied by other symptoms like fever or pain.
Identifying the underlying cause of a rash is crucial for effective treatment. Over-the-counter antihistamines or hydrocortisone creams can alleviate mild allergic reactions or irritations. However, for more severe cases or rashes that worsen, consulting a healthcare professional is recommended to ensure proper diagnosis and treatment options. Overall, being proactive and understanding the potential triggers of rashes can help in managing and preventing them in the future.
Hyaluronic acid is a naturally occurring substance in the body, particularly abundant in connective tissues, skin, and eyes. It plays a crucial role in retaining moisture, making it vital for maintaining healthy skin hydration and elasticity. As a humectant, hyaluronic acid can hold up to 1,000 times its weight in water, which is why it's a favored ingredient in many skincare products. When applied topically, it helps to draw moisture into the skin, leaving it plump and well-hydrated.
In addition to its hydrating properties, hyaluronic acid has gained popularity for its potential anti-aging benefits. It helps to diminish the appearance of fine lines and wrinkles by creating a smoother skin texture. Many experts recommend incorporating hyaluronic acid into your skincare routine, particularly if you have dry or dehydrated skin, as it can complement other treatments and products effectively. Overall, hyaluronic acid is an essential component for those seeking to enhance their skin’s moisture levels and achieve a youthful glow.
Hyaluronic acid is primarily known for its hydrating properties and is widely used in skincare products to retain moisture in the skin. While it can help in soothing and providing hydration to stressed or irritated skin, its direct efficacy in treating rashes is not well-established. Rashes can vary significantly in their causes—ranging from allergic reactions to infections—so the effectiveness of hyaluronic acid may depend on the underlying issue.
If the rash is due to dryness or irritation, the hydrating qualities of hyaluronic acid might offer some relief by preventing further moisture loss and promoting skin barrier function. However, for rashes that result from other causes, such as eczema or psoriasis, it would be best to consult with a dermatologist for a targeted treatment plan. As always, patch testing on a small area of skin before fully applying any new product can help prevent worsening of the rash.
Based on user reviews, the timeline for seeing results from this supplement can vary significantly. Some users report noticeable improvements in their skin conditions, including a reduction in rashes, as early as one week after starting the supplement. For instance, one user mentioned no rashes on their forehead and chin after two weeks of use Read Review. Another user cited an effect after just 1-2 weeks, though they still faced challenges with their skin rash persisting Read Review.
On the other hand, some users experienced a delay in seeing positive changes. One individual noted that it took about a month before their skin improved significantly, leading to smoother, healthier skin and the disappearance of the rash Read Review. Overall, while a subset of users report swift results, others may need to wait longer, suggesting that individual response times can vary widely.
The scientific research indicates that certain supplements, particularly those containing hyaluronic acid, may have beneficial effects on skin health, but their support specific to rashes is varied. For instance, a study examining the role of hyaluronic acid in skin regeneration revealed that its application led to significant improvements in skin hydration and health, with no adverse effects such as rash reported [1]. Additionally, another study focused on hyaluronic acid treatment for vaginal dryness noted improvements in symptoms, including rash, suggesting the active compound could provide relief in some contexts [4].
However, the research surrounding the use of hyaluronic acid in conjunction with other treatments shows some reports of rash as a side effect, particularly in the context of filler treatments [3]. Conversely, a topical cream, MAS063DP, specifically designed for atopic dermatitis, demonstrated effectiveness in reducing rash and related symptoms compared to a placebo, highlighting its potential as a treatment option [5]. Overall, while some supplements may have supporting research for general skin health, including the reduction of rashes, the effectiveness can significantly vary based on individual conditions and formulations.
Based on user reviews, several individuals have reported significant improvements in their skin symptoms after using the supplement. Many users noted a reduction in rashes and an overall enhancement in skin texture and hydration. For example, one user highlighted that after a month of use, their rash disappeared, and their complexion looked healthy and even Read Review. Another user shared that they experienced smoother, more radiant skin and found that normally recurrent winter rashes were effectively prevented while using the product Read Review.
However, individual experiences can vary, with some users reporting initial rashes as their bodies adjusted to the supplement. For example, one user experienced a notable rash initially but later found their skin's condition to improve rejuvenating Read Review. Another individual mentioned that while they had some challenges initially, after restarting the supplement, they noted less rashes and improved hydration in their skin Read Review. Overall, while many users have seen positive results, it's essential to recognize that reactions and effectiveness can differ from person to person.
Based on user reviews, combining this supplement with other products has yielded mixed results for managing rashes. Some users experienced a reduction in skin rashes when taking the supplement alongside collagen. For instance, one user noted that their skin's condition improved significantly in elasticity and smoothness, leading to a reduction in facial rashes Read Review. Another individual mentioned the prevention of winter rashes when using the supplement along with other treatments, resulting in smoother and more radiant skin Read Review.
However, there were reports of adverse reactions when combining the supplement with certain products. One user articulated experiencing a significant rash when taking the supplement, pointing out that their skin reacted negatively alongside other dietary elements Read Review. Additionally, another user suggested that difficulties arose from taking a hyaluronic acid supplement simultaneously, contributing to an increase in rashes rather than alleviating them Read Review. Overall, while some users found success in reducing rashes through complementary use, others reported worsened skin reactions, highlighting the individuality of skin response to combined supplementation.
According to user reviews, the dosage of Hyaluronic Acid for treating rashes seems to vary in its effectiveness. Some users reported adverse reactions, such as rashes appearing initially when starting the supplement, although these eventually cleared up after continued use. For instance, one user noted that they developed a rash when they began taking it, but after a month, their skin improved significantly, and the rash disappeared Read Review. Another user experienced a rash that persisted despite using the product Read Review.
In contrast, others experienced improvements in skin health with the proper dosage but emphasized the importance of hydration. One reviewer mentioned that adequate water intake is crucial for the supplement to be effective, suggesting that neglecting hydration might lead to increased rashes Read Review. Moreover, another user emphasized that taking the supplement after meals seemed to aid in absorption and reduce rashes Read Review. Overall, while user experiences with Hyaluronic Acid for rashes are mixed, incorporating a sufficient water intake and possibly using the supplement consistently over time may yield beneficial results.
7.5
No rashes after use
I bought this product based on word of mouth. After a week of not taking it, my skin felt smooth and moist. After two weeks, I noticed no rashes on my forehead and chin, unlike before.
6
Rash remained prevalent
1 people found this helpful
What are these supplements! I find myself needing to buy two bottles each month. The effect is felt in about 1-2 weeks. I’ve been using CoQ10; my skin rash remains quite prevalent despite the improvement in acne. If this drug does not yield substantial results, I might explore other options.
9
Rash eventually cleared
2 people found this helpful
Initially, rashes appeared on my skin when I started taking it, but I continued nonetheless. After a month, the skin changed and the rash disappeared. My complexion now looks healthy and even. I'm pleased with the result and have ordered more.
7.5
Winter rash prevented
1 people found this helpful
I really liked the effect of these capsules; they made my skin smoother and more radiant. Normally, in winter, I get skin rashes from the cold, but taking this drug has prevented that. My pores are less noticeable, and my skin tone is even. I was apprehensive about puffiness, but that was not an issue. I plan to continue taking it.
7.5
Reduced rash
I believe this aids the skin, and I also feel it reduces rashes, making my skin smoother.
7.5
Softer skin
After taking Collagen types 1 and 3 with Peptan for a month, I noticed no changes. My lips were excessively dry. After a month’s break, I resumed taking it and observed significant skin improvement; it became softer and more hydrated, with fewer rashes. Whenever a bump appeared, it healed more quickly, and my lips remained soft and moist. I took it after meals to aid absorption.
2
Noticeable rash observed
6 people found this helpful
To each their own; I did not like the product as I unfortunately developed a noticeable rash with this dosage. However, my mother has already finished her third jar! Even her beautician has noticed a clear effect from taking it. Her facial skin has become more radiant and puffy eyes less pronounced. An important point to note is that while taking this drug, one must drink a considerable amount of water; otherwise, it will not be effective.
2
Rashes appeared persistently
This hyaluronic acid supplement requires plenty of water; otherwise, your skin can dry out. I wasn't entirely pleased with the effect as I experienced more rashes when taking it.
8
Hyaluronic acid enhances skin regeneration
Transfersomal serum loading amniotic mesenchymal stem cells metabolite products with hyaluronic acid addition for skin regeneration in UV aging-induced mice.
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.
We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.
This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
9
Hyaluronic acid gel shows promise
Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy.
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
8
Hyaluronic acid treatments reduce wrinkles
A Randomized, Blinded, Prospective Clinical Study Comparing Small-Particle Versus Cohesive Polydensified Matrix Hyaluronic Acid Fillers for the Treatment of Perioral Rhytids.
We explored the effectiveness of two hyaluronic acid fillers in treating superficial wrinkles around the mouth. In a double-blind study involving 48 patients, we compared small-particle hyaluronic acid with lidocaine to cohesive polydensified matrix hyaluronic acid.
Both treatments reduced wrinkling, with notable results maintained for 180 days. However, the small-particle approach showed superior effectiveness as rated by both patients and investigators after the treatment period. While both products had similar safety profiles, adverse reactions included some rash among patients using cohesive matrix fillers.
9
Effective treatment for atopic dermatitis
A multicenter, randomized, vehicle-controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults.
We explored the impact of MAS063DP cream on mild to moderate atopic dermatitis in a clinical study involving 218 adults. Patients were randomly assigned to use either the MAS063DP cream or a placebo for 50 days, applying it three times daily to affected skin areas. Our results showed that MAS063DP was significantly more effective in reducing symptoms compared to the vehicle, with lower rates of rash reported in the treatment group. This indicates that MAS063DP cream is a promising option for managing atopic dermatitis.
References
Miatmoko A, Dewangga SS, Handoko KK, Legowo D, Purwantari KE, et al. Transfersomal serum loading amniotic mesenchymal stem cells metabolite products with hyaluronic acid addition for skin regeneration in UV aging-induced mice. Int J Pharm. 2024;667:124950. 10.1016/j.ijpharm.2024.124950
Shafuria A, Sufiawati I, Usman HA. A Rare Case of COVID-19-Induced Acute Exacerbation of Oral Dermatitis Herpetiformis in a Geriatric Patient. Int Med Case Rep J. 2023;16:129. 10.2147/IMCRJ.S401775
Polacco MA, Singleton AE, Luu T, Maas CS. A Randomized, Blinded, Prospective Clinical Study Comparing Small-Particle Versus Cohesive Polydensified Matrix Hyaluronic Acid Fillers for the Treatment of Perioral Rhytids. Aesthet Surg J. 2021;41:NP493. 10.1093/asj/sjaa161
Morali G, Polatti F, Metelitsa EN, Mascarucci P, Magnani P, et al. Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy. Arzneimittelforschung. 2006;56:230.
Abramovits W, Boguniewicz M. A multicenter, randomized, vehicle-controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults. J Drugs Dermatol. 2006;5:236.