Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.3
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Calcium (from tricalcium phosphate and calcium stearate in Serratericâ„¢)
29 mg
2%
Serrapeptase Enzyme (from Serratio sp.)
40,000 SPU**
â€
Nattokinase (from fibrinase enzyme)
2,000 FU***
â€
Top Medical Research Studies
7
We examined the effects of nattokinase, a protease found in natto, on allergies. Our study involved eight individuals who experienced allergic reactions after consuming natto, specifically the sticky substance surrounding the beans. Some participants tested negative for polygamma glutamic acid (PGA), which was previously identified as a potential allergen.
Throughout our investigation, we employed skin prick tests, immunoblotting, and ELISA to assess the reactivity to nattokinase and other components. Notably, we discovered that a subset of patients, particularly those who were negative for PGA, exhibited an allergic response to nattokinase. This finding suggests that nattokinase may act as a distinct allergen in certain individuals.
In the end, we identified nattokinase as a new allergen linked to natto allergy, particularly in those not sensitized to PGA. While our study highlights the allergenic potential of nattokinase, its broader implications for allergy treatment remain to be fully explored.
Throughout our investigation, we employed skin prick tests, immunoblotting, and ELISA to assess the reactivity to nattokinase and other components. Notably, we discovered that a subset of patients, particularly those who were negative for PGA, exhibited an allergic response to nattokinase. This finding suggests that nattokinase may act as a distinct allergen in certain individuals.
In the end, we identified nattokinase as a new allergen linked to natto allergy, particularly in those not sensitized to PGA. While our study highlights the allergenic potential of nattokinase, its broader implications for allergy treatment remain to be fully explored.
Read More
Most Useful Reviews
0
Anaphylaxis risk
25 people found this helpful
I intended to take this for cardiovascular benefits but had to return it due to a severe reaction. My throat is still swollen almost a day later. I’m unsure if it’s the serratiopeptidase or the nattokinase causing this. I have a history of anaphylaxis from food allergies, so I advise caution for anyone with similar conditions.
Read More
9
Better breathing
1 people found this helpful
Ultimately, I started to wake up with a normal breathing nose and ceased taking allergy medicine at night. The allergy itself seems to have disappeared. I cannot say for certain if it’s coincidence, but my sense of smell has improved. Serrapeptase appears to have addressed the internal fibroses, making my body feel lighter and more agile.
Read More
9
Sinuses clear
Clears sinuses! No more allergies, it wonderfully clears out my sinuses. Great quality and ingredients, with a convenient size and dosage.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
We examined the effects of nattokinase, a protease found in natto, on allergies. Our study involved eight individuals who experienced allergic reactions after consuming natto, specifically the sticky substance surrounding the beans. Some participants tested negative for polygamma glutamic acid (PGA), which was previously identified as a potential allergen.
Throughout our investigation, we employed skin prick tests, immunoblotting, and ELISA to assess the reactivity to nattokinase and other components. Notably, we discovered that a subset of patients, particularly those who were negative for PGA, exhibited an allergic response to nattokinase. This finding suggests that nattokinase may act as a distinct allergen in certain individuals.
In the end, we identified nattokinase as a new allergen linked to natto allergy, particularly in those not sensitized to PGA. While our study highlights the allergenic potential of nattokinase, its broader implications for allergy treatment remain to be fully explored.
Throughout our investigation, we employed skin prick tests, immunoblotting, and ELISA to assess the reactivity to nattokinase and other components. Notably, we discovered that a subset of patients, particularly those who were negative for PGA, exhibited an allergic response to nattokinase. This finding suggests that nattokinase may act as a distinct allergen in certain individuals.
In the end, we identified nattokinase as a new allergen linked to natto allergy, particularly in those not sensitized to PGA. While our study highlights the allergenic potential of nattokinase, its broader implications for allergy treatment remain to be fully explored.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
0
Anaphylaxis risk
25 people found this helpful
I intended to take this for cardiovascular benefits but had to return it due to a severe reaction. My throat is still swollen almost a day later. I’m unsure if it’s the serratiopeptidase or the nattokinase causing this. I have a history of anaphylaxis from food allergies, so I advise caution for anyone with similar conditions.
Read More
9
Better breathing
1 people found this helpful
Ultimately, I started to wake up with a normal breathing nose and ceased taking allergy medicine at night. The allergy itself seems to have disappeared. I cannot say for certain if it’s coincidence, but my sense of smell has improved. Serrapeptase appears to have addressed the internal fibroses, making my body feel lighter and more agile.
Read More
9
Sinuses clear
Clears sinuses! No more allergies, it wonderfully clears out my sinuses. Great quality and ingredients, with a convenient size and dosage.
Read More
9
Seasonal relief
I bought this for my boyfriend to assist with his seasonal allergies! He loves it and says it works better than allergy pills.
Read More
9
Allergy medication alternative
20 people found this helpful
My nasal passages used to get blocked at night and sometimes during the day due to allergies. This product has truly worked! I haven’t taken any allergy or sinus medications since February. If it also benefits circulatory health, that’s a bonus. This is definitely a must-buy for anyone struggling with allergies.
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Frequently Asked Questions
9
Better breathing
1 people found this helpful
Ultimately, I started to wake up with a normal breathing nose and ceased taking allergy medicine at night. The allergy itself seems to have disappeared. I cannot say for certain if it’s coincidence, but my sense of smell has improved. Serrapeptase appears to have addressed the internal fibroses, making my body feel lighter and more agile.
9
Sinuses clear
Clears sinuses! No more allergies, it wonderfully clears out my sinuses. Great quality and ingredients, with a convenient size and dosage.
7
Eased seasonal allergies
4 people found this helpful
I had been taking Dr Best serrapeptase for a while before switching to Natto-Serra a couple of months ago. This supplement aids with phlegm and my seasonal allergies. I also hope to see improvements concerning spider veins, but that will require time.
9
No allergies observed
2 people found this helpful
An excellent quality product with excellently chosen ingredients. I experienced no allergies or adverse reactions. The packaging is large and sufficient for a long time. The medium-sized capsules are neutral in taste. Delivery was quick and undamaged. The composition includes only healthy, natural ingredients, along with folic acid. I've noticed an improvement in my intestinal function and metabolism; changes were evident within a week, and my nervous system is functioning better now, with reduced anxiety.
9
Seasonal relief
I bought this for my boyfriend to assist with his seasonal allergies! He loves it and says it works better than allergy pills.
References
- Suzuki K, Nakamura M, Sato N, Futamura K, Matsunaga K, et al. Nattokinase (Bac s 1), a subtilisin family serine protease, is a novel allergen contained in the traditional Japanese fermented food natto. Allergol Int. 2023;72:279. 10.1016/j.alit.2022.11.010
