Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 18 Reviews
8.1
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Calcium (from tricalcium phosphate and calcium stearate in Serratericâ„¢)
29 mg
2%
Serrapeptase Enzyme (from Serratio sp.)
40,000 SPU**
†
Nattokinase (from fibrinase enzyme)
2,000 FU***
†

Top Medical Research Studies

8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Read More

Most Useful Reviews

9
No cold symptoms
53 people found this helpful
I tried this combined drug after taking Serrapeptase separately for five months. After a month of using it, I feel fantastic. I previously had chronic headaches and allergies, but most importantly, I experienced no symptoms of a cold. The combination of this drug with other medications and proper nutrition appears to have improved my metabolism, reducing swelling and stabilising my weight. I will continue taking it regularly.
Read More
8
Warm hands
32 people found this helpful
No more cold hands and feet. Until I started taking Natto-Serra, my hands and feet were perpetually cold. Now they feel warm unless I’m out in chilly weather! I’m sure it’s contributing to improved overall circulation.
Read More
10
No colds for months
5 people found this helpful
This jar contains Nattokinase and Serrapeptase. After taking them for the second time, I realised I hadn’t caught a cold for over six months! My order coincided with my family’s mild covid infection, which we barely noticed. These enzymes effectively break down foreign proteins and have antiviral properties that are remarkable during covid and post-covid. Ensure you take them on an empty stomach for the best results!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Read More

User Reviews

USERS' SCORE
Good
Based on 18 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No cold symptoms
53 people found this helpful
I tried this combined drug after taking Serrapeptase separately for five months. After a month of using it, I feel fantastic. I previously had chronic headaches and allergies, but most importantly, I experienced no symptoms of a cold. The combination of this drug with other medications and proper nutrition appears to have improved my metabolism, reducing swelling and stabilising my weight. I will continue taking it regularly.
Read More
8
Warm hands
32 people found this helpful
No more cold hands and feet. Until I started taking Natto-Serra, my hands and feet were perpetually cold. Now they feel warm unless I’m out in chilly weather! I’m sure it’s contributing to improved overall circulation.
Read More
10
No colds for months
5 people found this helpful
This jar contains Nattokinase and Serrapeptase. After taking them for the second time, I realised I hadn’t caught a cold for over six months! My order coincided with my family’s mild covid infection, which we barely noticed. These enzymes effectively break down foreign proteins and have antiviral properties that are remarkable during covid and post-covid. Ensure you take them on an empty stomach for the best results!
Read More
9
Effective cold prevention
2 people found this helpful
I never expected this product would be an essential part of my first aid kit. I take one capsule each morning on an empty stomach. It’s an excellent remedy for preventing colds and for use at the initial signs of illness. The quality is superb! Highly recommend!
Read More
7.5
Supports cold prevention
8 people found this helpful
My spouse’s nutritionist prescribed this natto-serrapeptase for vascular health. Older patients should take higher doses, so it was recommended my parents take these separately. These enzymes are remarkable! They are also effective at the first sign of a cold, and many find them beneficial for bronchitis.
Read More

Frequently Asked Questions

9
Quick recovery
I took it as support for colds and was very pleased with the result. My body quickly coped with the virus.
9
Effective cold relief
I highly recommend this product! It significantly alleviates my symptoms when I have a cold and speeds up recovery. However, for my maxillary sinus issues, I require a higher dosage. I ordered serropeptase at 12,000.
10
No colds for months
5 people found this helpful
This jar contains Nattokinase and Serrapeptase. After taking them for the second time, I realised I hadn’t caught a cold for over six months! My order coincided with my family’s mild covid infection, which we barely noticed. These enzymes effectively break down foreign proteins and have antiviral properties that are remarkable during covid and post-covid. Ensure you take them on an empty stomach for the best results!
7.5
Effective for colds
I took the drug to get rid of a persistent cold. Two weeks of use helped, and I did not experience any discomfort after taking it.
9
Recommended for colds
I took it for my mother, everything is fine. I also give it to my children and take it myself during colds. I recommend it.
8
Improved immunity
I purchased Natto-Serra to support cardiovascular health and improve my well-being. My energy increased, and I feel my immune system has become more resilient to colds. I did not experience any side effects, and overall, I am very pleased with my choice.
9
No cold symptoms
53 people found this helpful
I tried this combined drug after taking Serrapeptase separately for five months. After a month of using it, I feel fantastic. I previously had chronic headaches and allergies, but most importantly, I experienced no symptoms of a cold. The combination of this drug with other medications and proper nutrition appears to have improved my metabolism, reducing swelling and stabilising my weight. I will continue taking it regularly.
7.5
Supports cold prevention
8 people found this helpful
My spouse’s nutritionist prescribed this natto-serrapeptase for vascular health. Older patients should take higher doses, so it was recommended my parents take these separately. These enzymes are remarkable! They are also effective at the first sign of a cold, and many find them beneficial for bronchitis.
7
Supports respiratory health
Excellent! One of the best supplements for respiratory health. It helps with allergies and colds. I took it daily without any side effects for three months.
8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.

References

  1. Nara N, Kurosawa Y, Fuse-Hamaoka S, Kuroiwa M, Endo T, et al. A single dose of oral nattokinase accelerates skin temperature recovery after cold water immersion: A double-blind, placebo-controlled crossover study. Heliyon. 2023;9:e17951. 10.1016/j.heliyon.2023.e17951
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