Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 18 Reviews
8.5
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Calcium (from tricalcium phosphate and calcium stearate in Serrateric™)
29 mg
2%
Serrapeptase Enzyme (from Serratio sp.)
40,000 SPU**
Nattokinase (from fibrinase enzyme)
2,000 FU***

Top Medical Research Studies

8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Read More

Most Useful Reviews

9.5
No cold symptoms
I tried this combined drug after taking Serrapeptase separately for five months. After a month of using it, I feel fantastic. I previously had chronic headaches and allergies, but most importantly, I experienced no symptoms of a cold. The combination of this drug with other medications and proper nutrition appears to have improved my metabolism, reducing swelling and stabilising my weight. I will continue taking it regularly.
Read More
9
Warm hands
No more cold hands and feet. Until I started taking Natto-Serra, my hands and feet were perpetually cold. Now they feel warm unless I’m out in chilly weather! I’m sure it’s contributing to improved overall circulation.
Read More
10
No colds for months
This jar contains Nattokinase and Serrapeptase. After taking them for the second time, I realised I hadn’t caught a cold for over six months! My order coincided with my family’s mild covid infection, which we barely noticed. These enzymes effectively break down foreign proteins and have antiviral properties that are remarkable during covid and post-covid. Ensure you take them on an empty stomach for the best results!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Read More

User Reviews

USERS' SCORE
Good
Based on 18 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
No cold symptoms
I tried this combined drug after taking Serrapeptase separately for five months. After a month of using it, I feel fantastic. I previously had chronic headaches and allergies, but most importantly, I experienced no symptoms of a cold. The combination of this drug with other medications and proper nutrition appears to have improved my metabolism, reducing swelling and stabilising my weight. I will continue taking it regularly.
Read More
9
Warm hands
No more cold hands and feet. Until I started taking Natto-Serra, my hands and feet were perpetually cold. Now they feel warm unless I’m out in chilly weather! I’m sure it’s contributing to improved overall circulation.
Read More
10
No colds for months
This jar contains Nattokinase and Serrapeptase. After taking them for the second time, I realised I hadn’t caught a cold for over six months! My order coincided with my family’s mild covid infection, which we barely noticed. These enzymes effectively break down foreign proteins and have antiviral properties that are remarkable during covid and post-covid. Ensure you take them on an empty stomach for the best results!
Read More
9.5
Effective cold prevention
I never expected this product would be an essential part of my first aid kit. I take one capsule each morning on an empty stomach. It’s an excellent remedy for preventing colds and for use at the initial signs of illness. The quality is superb! Highly recommend!
Read More
8.8
Supports cold prevention
My spouse’s nutritionist prescribed this natto-serrapeptase for vascular health. Older patients should take higher doses, so it was recommended my parents take these separately. These enzymes are remarkable! They are also effective at the first sign of a cold, and many find them beneficial for bronchitis.
Read More

Frequently Asked Questions

Cold is a term that refers to a state of low temperature, often associated with a perceptibly chilly environment or the sensation of being cool to the touch. Scientifically, cold is relative to the presence and movement of heat, which is a measure of energy within matter. In everyday terms, we experience cold through weather changes, such as during winter months, and it can also be described in the context of specific temperature ranges – for example, temperatures below 32 degrees Fahrenheit (0 degrees Celsius) generally signify freezing conditions, which can impact outdoor activities, personal comfort, and various ecological systems.

Moreover, the sensation of cold is not solely dependent on temperature; factors like humidity and wind chill can enhance the feeling of coldness. When discussing cold in terms of human health, prolonged exposure to cold conditions can lead to hypothermia or frostbite if body heat is not effectively maintained. Hence, it's crucial to dress appropriately and take necessary precautions during colder months to prevent adverse effects. Understanding the concept of cold can help individuals better prepare for seasonal changes and ensure their comfort and safety.

Nattokinase is an enzyme extracted from a traditional Japanese food called natto, which is made from fermented soybeans. This enzyme is thought to have potential health benefits, primarily for cardiovascular health. Nattokinase is believed to support the breakdown of fibrin in the blood, which can help improve circulation and reduce the risk of blood clot formation. As a dietary supplement, it is often marketed for its possible ability to promote healthy blood flow and cardiovascular function.

While some studies suggest that nattokinase may help reduce blood pressure and enhance overall heart health, research is still ongoing. As with any supplement, it is essential to consult with a healthcare professional before adding nattokinase to your regimen, especially if you are on blood-thinning medications or have underlying health conditions. Overall, while nattokinase might offer some intriguing health benefits, more comprehensive studies are needed to fully understand its efficacy and safety profile.

When it comes to taking this supplement for cold relief, user experiences suggest that results can vary, but many report positive effects relatively quickly. Some users have noted that taking the supplement at the first sign of illness provides effective support, with one indicating that their body coped swiftly with the virus after introducing the supplement into their routine (Read Review). Additionally, a user mentioned feeling significant alleviation of symptoms and a speedier recovery after regular intake (Read Review).

For those looking for preventative effects, some have reported that consistent use over weeks has resulted in a noticeable reduction of colds and seasonal illnesses, with one individual stating they had not caught a cold for over six months while using the supplement (Read Review). Others mention that two weeks can yield substantial benefits in managing symptoms of a persistent cold (Read Review). Overall, while individual experiences may vary, users commonly report seeing results within a short timeframe of starting the supplement.

Nattokinase, a supplement derived from fermented soybeans, has been studied for its potential effects on recovery from cold exposure. A recent study indicated that a single dose of nattokinase may enhance recovery of skin temperature after immersion in cold water. Participants who took nattokinase showed faster warming of their hands compared to those who received a placebo, suggesting that this supplement could be beneficial for individuals who experience excessive cold sensitivity, such as women and the elderly [1].

While the research demonstrates that nattokinase can improve skin temperature recovery, it’s important to note that it did not affect cardiovascular responses during cold exposure. This specificity indicates that while nattokinase could assist in managing cold sensitivity, it does not influence heart rate or other related physiological changes typically triggered by cold environments [1]. Overall, while there is some scientific basis for the benefits of nattokinase regarding cold recovery, further research would be beneficial to fully understand its efficacy and potential applications.

Users have reported various improvements in their symptoms after using this supplement, particularly for cold prevention and respiratory health. Many individuals noted a significant reduction in the frequency of colds, with one user mentioning they had not fallen ill for over six months while using the product during their family's mild Covid infection (Read Review). Others experienced fast relief and recovery during cold symptoms, stating that they felt alleviated effects when taking the supplement at the onset of illness (Read Review). Additionally, some users expressed satisfaction with added benefits such as improved circulation and a boost in overall energy levels, suggesting that the combination of Nattokinase and Serrapeptase may enhance metabolic function too (Read Review).

Moreover, consistent feedback emphasized that users experienced notable symptom relief from respiratory issues, including allergies and sinus congestion, often reporting that they felt "fantastic" and observed clear improvements in their usual health and wellness (Read Review). Overall, while individual results can certainly differ, many users find this supplement to be a reliable support system for both preventing and alleviating cold symptoms.

Users have reported promising results when combining this supplement with other medications and proper nutrition for managing cold symptoms. Many note that using Nattokinase and Serrapeptase together has enhanced their effectiveness, leading to significant improvements in symptoms and overall health. One user highlighted that after taking the combination for a month, they felt fantastic and had no cold symptoms, attributing the improvements to the synergy of using this product along with a balanced diet (Read Review). Another review emphasized that the combined enzymes effectively prevent colds and help manage illness at the onset, indicating that these supplements serve as a beneficial part of their cold management strategy (Read Review).

Furthermore, users have reported that this supplement works well in conjunction with other cold remedies to enhance recovery. A user mentioned that they have been able to take the supplement at the first signs of a cold alongside their regular medications, resulting in quick alleviation of symptoms (Read Review). Others described their experiences of not only preventing colds but also managing ongoing respiratory issues such as allergies, claiming that the supplement brought visible benefits when used alongside their health regimen (Read Review). Overall, the feedback suggests that combining this supplement with other health practices is common and often leads to improved outcomes.

Users report varying experiences with the appropriate dosing of Nattokinase for treating colds. Many individuals seem to find success with a daily regimen of one capsule taken on an empty stomach, as noted in reviews where users experienced significant alleviation of cold symptoms and prevention (see review id='3948f9e2-1acc-4073-8a67-75a7feff8a35'). Others have taken multiple capsules, such as three before each meal, which some users found effective for clearing up colds (refer to review id='709eccc0-7ca4-492d-b615-e726eebdb3ed'). This suggests that there might be flexibility based on individual health needs and preferences.

Additionally, some users highlight the importance of taking these enzymes early at the onset of symptoms, indicating that they can be beneficial for preventing and managing cold symptoms (as seen in review id='2f40db9e-e0d3-4d84-8aee-8b00e40a0171'). A couple of reviewers noted the need for higher dosages for chronic issues or specific conditions, which implies that the right dose may differ based on individual health conditions and age (notably mentioned in review id='2f40db9e-e0d3-4d84-8aee-8b00e40a0171'). Overall, users advocate for a dose that suits their personal health scenario while maintaining good practices of taking the supplement properly.

9.5
Quick recovery
I took it as support for colds and was very pleased with the result. My body quickly coped with the virus.
9.5
Effective cold relief
I highly recommend this product! It significantly alleviates my symptoms when I have a cold and speeds up recovery. However, for my maxillary sinus issues, I require a higher dosage. I ordered serropeptase at 12,000.
10
No colds for months
This jar contains Nattokinase and Serrapeptase. After taking them for the second time, I realised I hadn’t caught a cold for over six months! My order coincided with my family’s mild covid infection, which we barely noticed. These enzymes effectively break down foreign proteins and have antiviral properties that are remarkable during covid and post-covid. Ensure you take them on an empty stomach for the best results!
8.8
Effective for colds
I took the drug to get rid of a persistent cold. Two weeks of use helped, and I did not experience any discomfort after taking it.
9.5
Recommended for colds
I took it for my mother, everything is fine. I also give it to my children and take it myself during colds. I recommend it.
9
Improved immunity
I purchased Natto-Serra to support cardiovascular health and improve my well-being. My energy increased, and I feel my immune system has become more resilient to colds. I did not experience any side effects, and overall, I am very pleased with my choice.
9.5
No cold symptoms
I tried this combined drug after taking Serrapeptase separately for five months. After a month of using it, I feel fantastic. I previously had chronic headaches and allergies, but most importantly, I experienced no symptoms of a cold. The combination of this drug with other medications and proper nutrition appears to have improved my metabolism, reducing swelling and stabilising my weight. I will continue taking it regularly.
8.8
Supports cold prevention
My spouse’s nutritionist prescribed this natto-serrapeptase for vascular health. Older patients should take higher doses, so it was recommended my parents take these separately. These enzymes are remarkable! They are also effective at the first sign of a cold, and many find them beneficial for bronchitis.
8.5
Supports respiratory health
Excellent! One of the best supplements for respiratory health. It helps with allergies and colds. I took it daily without any side effects for three months.
8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.

References

  1. Nara N, Kurosawa Y, Fuse-Hamaoka S, Kuroiwa M, Endo T, et al. A single dose of oral nattokinase accelerates skin temperature recovery after cold water immersion: A double-blind, placebo-controlled crossover study. Heliyon. 2023;9:e17951. doi:10.1016/j.heliyon.2023.e17951
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