Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.8
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Calcium (from tricalcium phosphate and calcium stearate in Serratericâ„¢)
29 mg
2%
Serrapeptase Enzyme (from Serratio sp.)
40,000 SPU**
†
Nattokinase (from fibrinase enzyme)
2,000 FU***
†

Top Medical Research Studies

We assessed the effects of nattokinase crude extract (NCE) on hepatocellular carcinoma (HCC) growth in mouse models. Our findings revealed that NCE significantly improved survival rates among treated mice and resulted in decreased tumor size. The extract lowered levels of specific proteins associated with cancer progression, further indicating its potential as a treatment option. Overall, we found that NCE leads to both enhanced survival and reduced tumor growth in HCC-bearing mice.
Read More
9.5
Effective novel liver fibrosis treatment
We explored a new approach to treat liver fibrosis using a combination of a nanosized iron-locked drug generator and oral nattokinase therapy. This innovative method allows drugs to bypass barriers in the liver, ensuring they reach damaged areas effectively.

By administering iron chelator deferasirox alongside, we witnessed improved drug activation precisely in the liver, leading to significant antifibrotic effects. Remarkably, this strategy not only reversed liver fibrosis but also minimized the toxic effects of iron in the liver.

Our findings could pave the way for similar treatments targeting liver diseases in the future.
Read More

Most Useful Reviews

9
Liver condition cleared
16 people found this helpful
This amazing drug cleaves the envelope of the virus among other benefits. I gave it to my husband for two months due to a small liver giongioma. Recently, we had an ultrasound and fibroscan, and thankfully, everything was clear! We're also supplementing with lecithin, hepatrol, magnesium, copper, zinc, omega, vitamins D + K, Q10, and carnitine.
Read More
10
Cyst disappearance
2 people found this helpful
After taking this for a few months and then going for a physical examination, I was surprised to find that the ovarian cysts and liver hemangioma had disappeared. I will continue to purchase it.
Read More
6
Inflammation reduction
Natto Serra comprises two natural enzymes and is advisable to take in courses. I consume it on an empty stomach twice daily. It has an excellent composition and quality, with medium-sized capsules. It helps reduce inflammation during disease exacerbation and effectively thins the blood.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.8
  • All Researches
9.5
Effective novel liver fibrosis treatment
We explored a new approach to treat liver fibrosis using a combination of a nanosized iron-locked drug generator and oral nattokinase therapy. This innovative method allows drugs to bypass barriers in the liver, ensuring they reach damaged areas effectively.

By administering iron chelator deferasirox alongside, we witnessed improved drug activation precisely in the liver, leading to significant antifibrotic effects. Remarkably, this strategy not only reversed liver fibrosis but also minimized the toxic effects of iron in the liver.

Our findings could pave the way for similar treatments targeting liver diseases in the future.
Read More
We assessed the effects of nattokinase crude extract (NCE) on hepatocellular carcinoma (HCC) growth in mouse models. Our findings revealed that NCE significantly improved survival rates among treated mice and resulted in decreased tumor size. The extract lowered levels of specific proteins associated with cancer progression, further indicating its potential as a treatment option. Overall, we found that NCE leads to both enhanced survival and reduced tumor growth in HCC-bearing mice.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Liver condition cleared
16 people found this helpful
This amazing drug cleaves the envelope of the virus among other benefits. I gave it to my husband for two months due to a small liver giongioma. Recently, we had an ultrasound and fibroscan, and thankfully, everything was clear! We're also supplementing with lecithin, hepatrol, magnesium, copper, zinc, omega, vitamins D + K, Q10, and carnitine.
Read More
10
Cyst disappearance
2 people found this helpful
After taking this for a few months and then going for a physical examination, I was surprised to find that the ovarian cysts and liver hemangioma had disappeared. I will continue to purchase it.
Read More
6
Inflammation reduction
Natto Serra comprises two natural enzymes and is advisable to take in courses. I consume it on an empty stomach twice daily. It has an excellent composition and quality, with medium-sized capsules. It helps reduce inflammation during disease exacerbation and effectively thins the blood.
Read More

Frequently Asked Questions

9
Liver condition cleared
16 people found this helpful
This amazing drug cleaves the envelope of the virus among other benefits. I gave it to my husband for two months due to a small liver giongioma. Recently, we had an ultrasound and fibroscan, and thankfully, everything was clear! We're also supplementing with lecithin, hepatrol, magnesium, copper, zinc, omega, vitamins D + K, Q10, and carnitine.
10
Cyst disappearance
2 people found this helpful
After taking this for a few months and then going for a physical examination, I was surprised to find that the ovarian cysts and liver hemangioma had disappeared. I will continue to purchase it.
6
Inflammation reduction
Natto Serra comprises two natural enzymes and is advisable to take in courses. I consume it on an empty stomach twice daily. It has an excellent composition and quality, with medium-sized capsules. It helps reduce inflammation during disease exacerbation and effectively thins the blood.
9.5
Effective novel liver fibrosis treatment
We explored a new approach to treat liver fibrosis using a combination of a nanosized iron-locked drug generator and oral nattokinase therapy. This innovative method allows drugs to bypass barriers in the liver, ensuring they reach damaged areas effectively.

By administering iron chelator deferasirox alongside, we witnessed improved drug activation precisely in the liver, leading to significant antifibrotic effects. Remarkably, this strategy not only reversed liver fibrosis but also minimized the toxic effects of iron in the liver.

Our findings could pave the way for similar treatments targeting liver diseases in the future.
We assessed the effects of nattokinase crude extract (NCE) on hepatocellular carcinoma (HCC) growth in mouse models. Our findings revealed that NCE significantly improved survival rates among treated mice and resulted in decreased tumor size. The extract lowered levels of specific proteins associated with cancer progression, further indicating its potential as a treatment option. Overall, we found that NCE leads to both enhanced survival and reduced tumor growth in HCC-bearing mice.

References

  1. Sun Q, Yang W, Song Z, Lu H, Shang W, et al. Precisely Controlling the Activation of an Iron-Locked Drug Generator in the Liver Sinusoid to Enhance Barrier Penetration and Reduction of Liver Fibrosis. J Am Chem Soc. 2024;146:33784. 10.1021/jacs.4c11988
  2. Yan Y, Wang Y, Qian J, Wu S, Ji Y, et al. Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice. J Microbiol Biotechnol. 2019;29:1281. 10.4014/jmb.1812.12058
image