My dad is a veterinarian. Eight years ago he had three stents after a quintuple bypass. They put him on blood thinners and told him that his heart had lost 80% of it function and that he had one foot in the grave and one foot on a banana peel. We looked at an alternative medicine newsletter and it had a big article on Nattokinase. We researched it through the medical journals and found that it has a lot of quality research behind it. He went in to the doctors about 2 years ago concerned that he was having a heart attach again. They could find nothing wrong with his heart. He went to the Everett Clinic in Washington where all of the specialists were under one roof. They had him provide 20 years of medical records. They said his heart was in great condition and he should keep doing what he was doing. The pain turned out to be caused by an Ulcer. This supplement is awesome