Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.8
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Nattokinase (from fibrinase enzymes)
2,000 FU**
†
Top Medical Research Studies
8
Nattokinase shows promise for Alzheimer’s
We explored how chronic Nattokinase (NK) treatment influences neuropsychiatric complications tied to Alzheimer's disease in mice. By administering NK to mice injected with β-amyloid peptide, we observed reduced signs of depression, anxiety, and memory impairments—key indicators of Alzheimer’s progression. NK treatment led to improvements in cognitive performance and normalized chemical changes in the brain, similar to the effects of donepezil, a known Alzheimer’s medication. This suggests that Nattokinase could be a promising avenue for addressing behavioral and cognitive challenges in Alzheimer’s.
Read More
7
We investigated how nattokinase could help in treating Alzheimer's disease in rats. Over 10 weeks, we divided rats into groups, some receiving nattokinase along with treatments that mimic Alzheimer's symptoms.
The results showed that nattokinase improved memory and decreased harmful proteins in the brain. Additionally, brain scans revealed less damage after treatment. This suggests that nattokinase may hold promise as a therapeutic option for Alzheimer's, though more human research is needed to confirm its effectiveness.
The results showed that nattokinase improved memory and decreased harmful proteins in the brain. Additionally, brain scans revealed less damage after treatment. This suggests that nattokinase may hold promise as a therapeutic option for Alzheimer's, though more human research is needed to confirm its effectiveness.
Read More
9
We explored the potential of nattokinase (NK) in alleviating the effects of Alzheimer's disease (AD) in a rat model. Over 45 days, rats given aluminum chloride to induce AD experienced typical symptoms, including increased brain enzymes linked to neurodegeneration. When treated with NK, these conditions improved; we observed reduced harmful brain activity and an increase in beneficial factors. The results indicate that NK could effectively influence AD-related factors, suggesting potential for therapeutic use in human patients.
Read More
Most Useful Reviews
9
Alzheimer's assistance
This top cardiovascular supplement aids in blood flow and supports Alzheimer’s management effectively, avoiding the adverse effects of traditional medications like aspirin.
Read More
7.5
Supports Alzheimer's treatment
118 people found this helpful
Nattokinase, derived from natto, greatly aids blood circulation. Its properties are multifaceted, beneficial for preventing osteoporosis, Alzheimer's, and heart conditions. As a food supplement, it normalises blood pressure and reduces cholesterol, offering a natural alternative to aspirin.
Read More
9
Benefits for Alzheimer's
2 people found this helpful
Nattokinase, extracted from natto, is known for improving heart health and lowering blood pressure. It breaks down blood clots and is beneficial for Alzheimer's, cardiovascular diseases, and osteoporosis.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
We explored the potential of nattokinase (NK) in alleviating the effects of Alzheimer's disease (AD) in a rat model. Over 45 days, rats given aluminum chloride to induce AD experienced typical symptoms, including increased brain enzymes linked to neurodegeneration. When treated with NK, these conditions improved; we observed reduced harmful brain activity and an increase in beneficial factors. The results indicate that NK could effectively influence AD-related factors, suggesting potential for therapeutic use in human patients.
Read More
8
Nattokinase shows promise for Alzheimer’s
We explored how chronic Nattokinase (NK) treatment influences neuropsychiatric complications tied to Alzheimer's disease in mice. By administering NK to mice injected with β-amyloid peptide, we observed reduced signs of depression, anxiety, and memory impairments—key indicators of Alzheimer’s progression. NK treatment led to improvements in cognitive performance and normalized chemical changes in the brain, similar to the effects of donepezil, a known Alzheimer’s medication. This suggests that Nattokinase could be a promising avenue for addressing behavioral and cognitive challenges in Alzheimer’s.
Read More
8
Nattokinase shows promise for Alzheimer's
We investigated the potential of nattokinase, an enzyme known for its beneficial effects, in treating Alzheimer's disease. By creating a specialized delivery system using polymeric nanoparticles, we aimed to enhance the enzyme's effectiveness against amyloid plaques. Our findings indicate that this innovative formulation can reduce amyloid aggregation while maintaining the stability and activity of nattokinase. However, while the results are promising, further research is necessary to fully understand its implications for Alzheimer's treatment.
Read More
8
Nattokinase shows potential for Alzheimer's
To assess how fermented soybean nutrients, specifically nattokinase, affect Alzheimer's, we studied their impact on rats with cognitive deficits induced by colchicine.
Our results showed that these nutrients significantly improved learning and memory. We observed a notable boost in the activity of acetylcholinesterase, suggesting potential neuroprotective effects.
Moreover, the treatment reduced oxidative stress markers in the brain, indicating its role in combating cognitive issues linked to Alzheimer's. Overall, these findings hint at a promising avenue for future Alzheimer's treatments using nattokinase.
Our results showed that these nutrients significantly improved learning and memory. We observed a notable boost in the activity of acetylcholinesterase, suggesting potential neuroprotective effects.
Moreover, the treatment reduced oxidative stress markers in the brain, indicating its role in combating cognitive issues linked to Alzheimer's. Overall, these findings hint at a promising avenue for future Alzheimer's treatments using nattokinase.
Read More
7
We investigated how nattokinase could help in treating Alzheimer's disease in rats. Over 10 weeks, we divided rats into groups, some receiving nattokinase along with treatments that mimic Alzheimer's symptoms.
The results showed that nattokinase improved memory and decreased harmful proteins in the brain. Additionally, brain scans revealed less damage after treatment. This suggests that nattokinase may hold promise as a therapeutic option for Alzheimer's, though more human research is needed to confirm its effectiveness.
The results showed that nattokinase improved memory and decreased harmful proteins in the brain. Additionally, brain scans revealed less damage after treatment. This suggests that nattokinase may hold promise as a therapeutic option for Alzheimer's, though more human research is needed to confirm its effectiveness.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Alzheimer's assistance
This top cardiovascular supplement aids in blood flow and supports Alzheimer’s management effectively, avoiding the adverse effects of traditional medications like aspirin.
Read More
7.5
Supports Alzheimer's treatment
118 people found this helpful
Nattokinase, derived from natto, greatly aids blood circulation. Its properties are multifaceted, beneficial for preventing osteoporosis, Alzheimer's, and heart conditions. As a food supplement, it normalises blood pressure and reduces cholesterol, offering a natural alternative to aspirin.
Read More
9
Benefits for Alzheimer's
2 people found this helpful
Nattokinase, extracted from natto, is known for improving heart health and lowering blood pressure. It breaks down blood clots and is beneficial for Alzheimer's, cardiovascular diseases, and osteoporosis.
Read More
7.5
Alzheimer's prevention
1 people found this helpful
Nattokinase is a renowned supplement, especially post-COVID. It addresses Alzheimer’s and supports cardiovascular health by dissolving fibrin, aiding blood flow without the side effects of aspirin.
Read More
7.5
Alzheimer's improvement
1 people found this helpful
Nattokinase is vital for health, particularly post-COVID. It thins blood and dissolves clots, benefiting Alzheimer's, enhancing cardiovascular health, and preventing headaches.
Read More
Frequently Asked Questions
7.5
Alzheimer's therapy
Regular use of Nattokinase is recommended to maintain healthy blood vessels and support conditions like Alzheimer's and osteoporosis, making it an excellent supplementary therapy.
7.5
Prevention benefits
I take nattokinase daily on an empty stomach to maintain clear blood vessels by reducing undesirable proteins like fibrin, which can contribute to Alzheimer's disease. As most people can't eat natto regularly, taking nattokinase supplements is an excellent alternative.
9
Alzheimer's assistance
This top cardiovascular supplement aids in blood flow and supports Alzheimer’s management effectively, avoiding the adverse effects of traditional medications like aspirin.
6
Useful for Alzheimer's
36 people found this helpful
Nattokinase is a powerful enzyme that enhances blood fluidity. It helps prevent Alzheimer's and lowers cholesterol, making it a great alternative to aspirin for maintaining blood density and cardiovascular health.
7.5
Supports Alzheimer's treatment
118 people found this helpful
Nattokinase, derived from natto, greatly aids blood circulation. Its properties are multifaceted, beneficial for preventing osteoporosis, Alzheimer's, and heart conditions. As a food supplement, it normalises blood pressure and reduces cholesterol, offering a natural alternative to aspirin.
9
Benefits for Alzheimer's
2 people found this helpful
Nattokinase, extracted from natto, is known for improving heart health and lowering blood pressure. It breaks down blood clots and is beneficial for Alzheimer's, cardiovascular diseases, and osteoporosis.
7.5
Alzheimer's prevention
1 people found this helpful
Nattokinase is a renowned supplement, especially post-COVID. It addresses Alzheimer’s and supports cardiovascular health by dissolving fibrin, aiding blood flow without the side effects of aspirin.
7.5
Heart health support
Nattokinase is an enzyme from natto, aiding blood fluidity and circulation, with potential benefits for Alzheimer’s treatment. It serves as an alternative to aspirin for maintaining blood density. This supplement may prevent osteoporosis, assist with Alzheimer's, and lower cholesterol levels. Its action normalises pressure and alleviates varicose veins, while reducing headaches by increasing oxygen in tissues. Overall, it may significantly contribute to cardiovascular health and reduce risks associated with blood clots.
7.5
Supports Alzheimer's health
Nattokinase enhances longevity and health in Japan, helping to dissolve blood clots and reduce Alzheimer’s and cardiovascular risks. It is essential to avoid combining it with other blood thinners.
7.5
Benefits Alzheimer's treatment
Nattokinase normalises blood circulation and is highly beneficial for Alzheimer’s and cardiovascular health. It has various properties including strengthening bones and cleansing the body. Consult a specialist for dosage.
7.5
Cholesterol reduction
The properties of nattokinase include high fibrinolytic activity, which benefits heart and blood vessel health, and supports Alzheimer's treatment. It strengthens bones, helps detoxify the body, and reduces cholesterol accumulation. Nattokinase enhances metabolism and aids in weight loss. It's important to consult a specialist for the correct dosage.
7
We investigated how nattokinase could help in treating Alzheimer's disease in rats. Over 10 weeks, we divided rats into groups, some receiving nattokinase along with treatments that mimic Alzheimer's symptoms.
The results showed that nattokinase improved memory and decreased harmful proteins in the brain. Additionally, brain scans revealed less damage after treatment. This suggests that nattokinase may hold promise as a therapeutic option for Alzheimer's, though more human research is needed to confirm its effectiveness.
The results showed that nattokinase improved memory and decreased harmful proteins in the brain. Additionally, brain scans revealed less damage after treatment. This suggests that nattokinase may hold promise as a therapeutic option for Alzheimer's, though more human research is needed to confirm its effectiveness.
8
Nattokinase shows promise for Alzheimer’s
We explored how chronic Nattokinase (NK) treatment influences neuropsychiatric complications tied to Alzheimer's disease in mice. By administering NK to mice injected with β-amyloid peptide, we observed reduced signs of depression, anxiety, and memory impairments—key indicators of Alzheimer’s progression. NK treatment led to improvements in cognitive performance and normalized chemical changes in the brain, similar to the effects of donepezil, a known Alzheimer’s medication. This suggests that Nattokinase could be a promising avenue for addressing behavioral and cognitive challenges in Alzheimer’s.
8
Nattokinase shows promise for Alzheimer's
We investigated the potential of nattokinase, an enzyme known for its beneficial effects, in treating Alzheimer's disease. By creating a specialized delivery system using polymeric nanoparticles, we aimed to enhance the enzyme's effectiveness against amyloid plaques. Our findings indicate that this innovative formulation can reduce amyloid aggregation while maintaining the stability and activity of nattokinase. However, while the results are promising, further research is necessary to fully understand its implications for Alzheimer's treatment.
8
Nattokinase shows potential for Alzheimer's
To assess how fermented soybean nutrients, specifically nattokinase, affect Alzheimer's, we studied their impact on rats with cognitive deficits induced by colchicine.
Our results showed that these nutrients significantly improved learning and memory. We observed a notable boost in the activity of acetylcholinesterase, suggesting potential neuroprotective effects.
Moreover, the treatment reduced oxidative stress markers in the brain, indicating its role in combating cognitive issues linked to Alzheimer's. Overall, these findings hint at a promising avenue for future Alzheimer's treatments using nattokinase.
Our results showed that these nutrients significantly improved learning and memory. We observed a notable boost in the activity of acetylcholinesterase, suggesting potential neuroprotective effects.
Moreover, the treatment reduced oxidative stress markers in the brain, indicating its role in combating cognitive issues linked to Alzheimer's. Overall, these findings hint at a promising avenue for future Alzheimer's treatments using nattokinase.
9
We explored the potential of nattokinase (NK) in alleviating the effects of Alzheimer's disease (AD) in a rat model. Over 45 days, rats given aluminum chloride to induce AD experienced typical symptoms, including increased brain enzymes linked to neurodegeneration. When treated with NK, these conditions improved; we observed reduced harmful brain activity and an increase in beneficial factors. The results indicate that NK could effectively influence AD-related factors, suggesting potential for therapeutic use in human patients.
References
- Tanikawa T, Yu J, Hsu K, Chen S, Ishii A, et al. Effect of Nattokinase in D-galactose- and Aluminum Chloride-induced Alzheimer's Disease Model of Rat. In Vivo. 2024;38:2672. 10.21873/invivo.13744
- Naik S, Katariya R, Shelke S, Patravale V, Umekar M, et al. Nattokinase prevents β-amyloid peptide (Aβ) induced neuropsychiatric complications, neuroinflammation and BDNF signalling disruption in mice. Eur J Pharmacol. 2023;952:175821. 10.1016/j.ejphar.2023.175821
- Bhatt PC, Verma A, Al-Abbasi FA, Anwar F, Kumar V, et al. Development of surface-engineered PLGA nanoparticulate-delivery system of Tet1-conjugated nattokinase enzyme for inhibition of Aβ plaques in Alzheimer's disease. Int J Nanomedicine. 2017;12:8749. 10.2147/IJN.S144545
- Bhatt PC, Pathak S, Kumar V, Panda BP. Attenuation of neurobehavioral and neurochemical abnormalities in animal model of cognitive deficits of Alzheimer's disease by fermented soybean nanonutraceutical. Inflammopharmacology. 2018;26:105. 10.1007/s10787-017-0381-9
- Fadl NN, Ahmed HH, Booles HF, Sayed AH. Serrapeptase and nattokinase intervention for relieving Alzheimer's disease pathophysiology in rat model. Hum Exp Toxicol. 2013;32:721. 10.1177/0960327112467040
