Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 25 Reviews
8.7
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Nattokinase (from fibrinase enzymes)
2,000 FU**

Top Medical Research Studies

8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Read More

Most Useful Reviews

10
Circulation improvement
48 people found this helpful
I bought this for my husband's cold left foot, which he couldn't feel for years. Within 24 hours of taking it, he regained feeling, and it felt warm again! He had thought he would suffer forever. Now, he’s active and claims he has his life back—his hands are warm too. He takes one capsule in the morning and another before dinner. We ordered multiple bottles to keep this up. We're incredibly grateful for this product!
Read More
9
Constant warmth
23 people found this helpful
This drug has worked wonders for my husband, who always had cold hands and feet. Since taking it, he no longer suffers from the cold and stays warm all the time. It's clear that it improves his circulation. Our whole family benefited from it when we had covid, and it positively affected us. If you find this review helpful, please give it a thumbs up!
Read More
10
Cold feet resolved
10 people found this helpful
Nattokinase is sensational! I've suffered from cold feet for 40 years, but this product eliminated the issue in just 24 hours. I will continue purchasing it.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.

Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.

Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.

Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Read More

User Reviews

USERS' SCORE
Good
Based on 25 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Circulation improvement
48 people found this helpful
I bought this for my husband's cold left foot, which he couldn't feel for years. Within 24 hours of taking it, he regained feeling, and it felt warm again! He had thought he would suffer forever. Now, he’s active and claims he has his life back—his hands are warm too. He takes one capsule in the morning and another before dinner. We ordered multiple bottles to keep this up. We're incredibly grateful for this product!
Read More
9
Constant warmth
23 people found this helpful
This drug has worked wonders for my husband, who always had cold hands and feet. Since taking it, he no longer suffers from the cold and stays warm all the time. It's clear that it improves his circulation. Our whole family benefited from it when we had covid, and it positively affected us. If you find this review helpful, please give it a thumbs up!
Read More
10
Cold feet resolved
10 people found this helpful
Nattokinase is sensational! I've suffered from cold feet for 40 years, but this product eliminated the issue in just 24 hours. I will continue purchasing it.
Read More
9
Cold tolerance
2 people found this helpful
This worked extremely quickly for me. I now tolerate the cold much better, with my hands becoming warm.
Read More
9
Supports lung function
We take this to enhance lung and bronchi function since we live in a cold climate and frequently lack oxygen. Thanks to nattokinase, I easily endured COVID without feeling heaviness in my airways and suffer less from laryngitis. The capsules are small and convenient.
Read More

Frequently Asked Questions

10
Circulation improvement
48 people found this helpful
I bought this for my husband's cold left foot, which he couldn't feel for years. Within 24 hours of taking it, he regained feeling, and it felt warm again! He had thought he would suffer forever. Now, he’s active and claims he has his life back—his hands are warm too. He takes one capsule in the morning and another before dinner. We ordered multiple bottles to keep this up. We're incredibly grateful for this product!
9
Instant symptom relief
I didn't expect such an instant effect! I initially took it for candida, but when my husband got a sore throat and cold symptoms, within two days of using this supplement, all his symptoms vanished without any gargling. It's a miracle supplement!
7.5
Effective for cold extremities
1 people found this helpful
Very good for cold extremities in winter; it works after a week of taking the treatment.
10
Cold feet resolved
10 people found this helpful
Nattokinase is sensational! I've suffered from cold feet for 40 years, but this product eliminated the issue in just 24 hours. I will continue purchasing it.
9
Constant warmth
23 people found this helpful
This drug has worked wonders for my husband, who always had cold hands and feet. Since taking it, he no longer suffers from the cold and stays warm all the time. It's clear that it improves his circulation. Our whole family benefited from it when we had covid, and it positively affected us. If you find this review helpful, please give it a thumbs up!
7.5
Immunity support
Great! I take this vitamin in autumn and winter to support my immunity. I have only caught a cold once! I feel brilliant, and the supplement in capsules is convenient and easy to wash down with water.
7.5
Leg heaviness relief
I decided to try nattokinase for its blood vessel benefits. After a month’s course, I noticed my legs tire less often and I experience cold extremities much less. My overall health has improved significantly, and I have more energy. I plan to continue this during sedentary periods.
7.5
Positive immunity boost
Good quantity at a reasonable price. Contrary to reviews mentioning a smell, I found none upon opening. I take NAC alongside Serrareptase, and it positively impacts my immunity. Colds have become easier and quicker to manage.
9
Effective remedy
My sister advised me to take various supplements when I caught a cold. The effect is obvious. I will purchase it again.
6
Helps with blood flow
1 people found this helpful
An excellent natural remedy for thinning blood; the main thing is not to combine it with food for best effects. It also loosens mucus from colds and promotes excretion.
7.5
Prevents colds
3 people found this helpful
I recommend it. I read in other reviews to take it before bed, so I have taken one tablet at night. It helps me rise in the morning, and I have yet to catch a cold.
7.5
Improved circulation
The quality of this nattokinase supplement is excellent, containing a potent dose of 2,000 fibrinolytic units (FUs) per serving, which supports circulation and healthy blood flow. The biggest benefit I've observed is the enhancement of my circulation; I’ve experienced fewer instances of cold hands and feet, which used to be a challenge for me.

References

  1. Nara N, Kurosawa Y, Fuse-Hamaoka S, Kuroiwa M, Endo T, et al. A single dose of oral nattokinase accelerates skin temperature recovery after cold water immersion: A double-blind, placebo-controlled crossover study. Heliyon. 2023;9:e17951. 10.1016/j.heliyon.2023.e17951
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