Overview
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
USERS' SCORE
Good
Based on 28 Reviews
8.1
Supplement Facts
Serving Size: 1 Veggie Capsule
Serving Per Container: 60
Amount Per Serving
%DV
Vitamin K2 (from MenaQ7® Menaquinone, MK-7)
45 mcg
38%
Top Medical Research Studies
9
Vitamin K1 reduces coronary calcifications
We aimed to determine how vitamin K1 affects coronary artery calcifications in patients undergoing hemodialysis. In our study with 60 participants, we compared the effects of intravenous vitamin K1 against a placebo over 12 months.
The results showed that vitamin K1 significantly slowed the progression of coronary artery calcifications by 55%, compared to the placebo group. This finding suggests vitamin K1 may offer an important benefit in managing heart health for those with chronic kidney disease.
The results showed that vitamin K1 significantly slowed the progression of coronary artery calcifications by 55%, compared to the placebo group. This finding suggests vitamin K1 may offer an important benefit in managing heart health for those with chronic kidney disease.
Read More
7
Real-world effectiveness of blood thinners
We explored how well the outcomes of landmark trials for two blood thinners—apixaban and rivaroxaban—hold up in real-world atrial fibrillation (AF) patients. By examining data from the GARFIELD-AF registry, we found that patients on these treatments had similar results in preventing strokes, bleeding, and overall mortality when compared to those on vitamin K antagonists.
While apixaban showed promising results, rivaroxaban had more mixed findings, yet overall, the effectiveness and safety were largely in line with the original trials. This suggests that these medications can be appropriately used in everyday medical practice.
While apixaban showed promising results, rivaroxaban had more mixed findings, yet overall, the effectiveness and safety were largely in line with the original trials. This suggests that these medications can be appropriately used in everyday medical practice.
Read More
4
Vitamin K antagonists raise mortality risk
We analyzed data from a study involving patients who underwent mitral valve repair and had atrial fibrillation, comparing the effects of direct oral anticoagulants to vitamin K antagonists (VKAs).
Surprisingly, we found that both treatments led to similar rates of serious complications, like strokes or bleeding. However, those on VKAs showed a significantly higher overall mortality. This suggests that while both anticoagulants may work similarly for immediate outcomes, VKAs might come with increased risks for longer-term survival. Further research is needed to clarify the best options for these patients.
Surprisingly, we found that both treatments led to similar rates of serious complications, like strokes or bleeding. However, those on VKAs showed a significantly higher overall mortality. This suggests that while both anticoagulants may work similarly for immediate outcomes, VKAs might come with increased risks for longer-term survival. Further research is needed to clarify the best options for these patients.
Read More
Most Useful Reviews
9
Prevents vascular calcification
6 people found this helpful
This form of Vitamin K2 is essential for preventing vascular calcification, especially when taking high doses of Vitamin D3. I prefer to take them from separate jars as it suits me better. I recommend this combination wholeheartedly for its health benefits, including heart disease prevention.
Read More
9
Remarkable dental recovery
6 people found this helpful
This vitamin combined with D3 has been a blessing for my periodontal health! I experienced significant dental issues, but after two months of taking it, my condition improved. My dentist was astonished at the results! I believe this supplement can help others avoid similar dental problems and heart disease.
Read More
9
Essential for calcium absorption
3 people found this helpful
This product is not commonly found in pharmacies due to its MK-7 formula. I recommend purchasing it online for its great value. I've been using it for four months to improve vitamin D absorption, calcium distribution, and heart disease health. It’s crucial for maintaining bone and cardiovascular health.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
- All Researches
9
Vitamin K1 reduces coronary calcifications
We aimed to determine how vitamin K1 affects coronary artery calcifications in patients undergoing hemodialysis. In our study with 60 participants, we compared the effects of intravenous vitamin K1 against a placebo over 12 months.
The results showed that vitamin K1 significantly slowed the progression of coronary artery calcifications by 55%, compared to the placebo group. This finding suggests vitamin K1 may offer an important benefit in managing heart health for those with chronic kidney disease.
The results showed that vitamin K1 significantly slowed the progression of coronary artery calcifications by 55%, compared to the placebo group. This finding suggests vitamin K1 may offer an important benefit in managing heart health for those with chronic kidney disease.
Read More
9
We analyzed a study comparing two anticoagulation options—direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs)—in patients with non-valvular atrial fibrillation who faced blood clots despite previous treatment.
Our findings reveal that those on DOACs had significantly fewer cardioembolic events and complications following left atrial appendage closure.
In contrast, patients on VKAs did not show the same benefit, which suggests that DOACs may be a more effective option for ongoing treatment in these cases.
Our findings reveal that those on DOACs had significantly fewer cardioembolic events and complications following left atrial appendage closure.
In contrast, patients on VKAs did not show the same benefit, which suggests that DOACs may be a more effective option for ongoing treatment in these cases.
Read More
7
Real-world effectiveness of blood thinners
We explored how well the outcomes of landmark trials for two blood thinners—apixaban and rivaroxaban—hold up in real-world atrial fibrillation (AF) patients. By examining data from the GARFIELD-AF registry, we found that patients on these treatments had similar results in preventing strokes, bleeding, and overall mortality when compared to those on vitamin K antagonists.
While apixaban showed promising results, rivaroxaban had more mixed findings, yet overall, the effectiveness and safety were largely in line with the original trials. This suggests that these medications can be appropriately used in everyday medical practice.
While apixaban showed promising results, rivaroxaban had more mixed findings, yet overall, the effectiveness and safety were largely in line with the original trials. This suggests that these medications can be appropriately used in everyday medical practice.
Read More
5
Vitamin K antagonists: outcomes assessed
We investigated the impact of vitamin K antagonists (VKA) on patients with atrial fibrillation (AF). Our study included 1,350 patients who received VKA for at least a year, tracking various outcomes like cardiovascular death and thromboembolic events.
Interestingly, while we noted predictors for these clinical outcomes—like previous thromboembolism or bleeding—no significant improvement in heart disease was directly linked to vitamin K treatment itself. Instead, factors such as age and kidney function played crucial roles in determining patient outcomes.
Interestingly, while we noted predictors for these clinical outcomes—like previous thromboembolism or bleeding—no significant improvement in heart disease was directly linked to vitamin K treatment itself. Instead, factors such as age and kidney function played crucial roles in determining patient outcomes.
Read More
4
Vitamin K antagonists raise mortality risk
We analyzed data from a study involving patients who underwent mitral valve repair and had atrial fibrillation, comparing the effects of direct oral anticoagulants to vitamin K antagonists (VKAs).
Surprisingly, we found that both treatments led to similar rates of serious complications, like strokes or bleeding. However, those on VKAs showed a significantly higher overall mortality. This suggests that while both anticoagulants may work similarly for immediate outcomes, VKAs might come with increased risks for longer-term survival. Further research is needed to clarify the best options for these patients.
Surprisingly, we found that both treatments led to similar rates of serious complications, like strokes or bleeding. However, those on VKAs showed a significantly higher overall mortality. This suggests that while both anticoagulants may work similarly for immediate outcomes, VKAs might come with increased risks for longer-term survival. Further research is needed to clarify the best options for these patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 28 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Prevents vascular calcification
6 people found this helpful
This form of Vitamin K2 is essential for preventing vascular calcification, especially when taking high doses of Vitamin D3. I prefer to take them from separate jars as it suits me better. I recommend this combination wholeheartedly for its health benefits, including heart disease prevention.
Read More
9
Remarkable dental recovery
6 people found this helpful
This vitamin combined with D3 has been a blessing for my periodontal health! I experienced significant dental issues, but after two months of taking it, my condition improved. My dentist was astonished at the results! I believe this supplement can help others avoid similar dental problems and heart disease.
Read More
9
Essential for calcium absorption
3 people found this helpful
This product is not commonly found in pharmacies due to its MK-7 formula. I recommend purchasing it online for its great value. I've been using it for four months to improve vitamin D absorption, calcium distribution, and heart disease health. It’s crucial for maintaining bone and cardiovascular health.
Read More
9
Supports heart health
1 people found this helpful
This product contains high-quality K2 MK-7 and is vital for calcium regulation in bones and preventing its deposition in blood vessels. Regular use has improved my bone and heart health significantly. I recommend it for anyone looking to enhance their overall health.
Read More
9
Cardiovascular protection
1 people found this helpful
This Vitamin K2 is excellent for the cardiovascular system. It redistributes calcium, clearing it from arteries, thus protecting against heart disease.
Read More
Frequently Asked Questions
9
Remarkable dental recovery
6 people found this helpful
This vitamin combined with D3 has been a blessing for my periodontal health! I experienced significant dental issues, but after two months of taking it, my condition improved. My dentist was astonished at the results! I believe this supplement can help others avoid similar dental problems and heart disease.
9
Essential for calcium absorption
3 people found this helpful
This product is not commonly found in pharmacies due to its MK-7 formula. I recommend purchasing it online for its great value. I've been using it for four months to improve vitamin D absorption, calcium distribution, and heart disease health. It’s crucial for maintaining bone and cardiovascular health.
9
Supports heart health
1 people found this helpful
This product contains high-quality K2 MK-7 and is vital for calcium regulation in bones and preventing its deposition in blood vessels. Regular use has improved my bone and heart health significantly. I recommend it for anyone looking to enhance their overall health.
9
Strengthened heart
After taking K2, I've noticed my teeth are stronger and my heart feels more robust. I will continue with Doctor's Best for its benefits.
7.5
Vascular health improvement
6 people found this helpful
I take it daily with Vitamin D3, as they work together to ensure calcium is absorbed by bones rather than blood vessels, benefiting heart disease. The soft gels are small and easy to swallow. This K2 form (Menaquinone-7) is highly effective for vascular health, joint health, and inflammation.
9
Supports heart health
1 people found this helpful
Doctor's Best, Natural Vitamin K2 MK-7 with MenaQ7 is crucial when taking vitamin D3, as it helps direct calcium to the bones and prevents its deposit in vessels, reducing risks of heart disease and osteoporosis. I take it daily with my breakfast for optimal absorption, knowing that K2 significantly contributes to maintaining vascular integrity and reducing disease risk.
9
Prevents vascular calcification
6 people found this helpful
This form of Vitamin K2 is essential for preventing vascular calcification, especially when taking high doses of Vitamin D3. I prefer to take them from separate jars as it suits me better. I recommend this combination wholeheartedly for its health benefits, including heart disease prevention.
9
Longevity benefits
1 people found this helpful
Vitamin K2 may extend life, as high doses correlate with a 50% decrease in coronary heart disease risk. It's essential to supplement due to common deficiencies, which negatively impact bones and heart health.
5
Vitamin K antagonists: outcomes assessed
We investigated the impact of vitamin K antagonists (VKA) on patients with atrial fibrillation (AF). Our study included 1,350 patients who received VKA for at least a year, tracking various outcomes like cardiovascular death and thromboembolic events.
Interestingly, while we noted predictors for these clinical outcomes—like previous thromboembolism or bleeding—no significant improvement in heart disease was directly linked to vitamin K treatment itself. Instead, factors such as age and kidney function played crucial roles in determining patient outcomes.
Interestingly, while we noted predictors for these clinical outcomes—like previous thromboembolism or bleeding—no significant improvement in heart disease was directly linked to vitamin K treatment itself. Instead, factors such as age and kidney function played crucial roles in determining patient outcomes.
4
Vitamin K antagonists raise mortality risk
We analyzed data from a study involving patients who underwent mitral valve repair and had atrial fibrillation, comparing the effects of direct oral anticoagulants to vitamin K antagonists (VKAs).
Surprisingly, we found that both treatments led to similar rates of serious complications, like strokes or bleeding. However, those on VKAs showed a significantly higher overall mortality. This suggests that while both anticoagulants may work similarly for immediate outcomes, VKAs might come with increased risks for longer-term survival. Further research is needed to clarify the best options for these patients.
Surprisingly, we found that both treatments led to similar rates of serious complications, like strokes or bleeding. However, those on VKAs showed a significantly higher overall mortality. This suggests that while both anticoagulants may work similarly for immediate outcomes, VKAs might come with increased risks for longer-term survival. Further research is needed to clarify the best options for these patients.
9
Vitamin K1 reduces coronary calcifications
We aimed to determine how vitamin K1 affects coronary artery calcifications in patients undergoing hemodialysis. In our study with 60 participants, we compared the effects of intravenous vitamin K1 against a placebo over 12 months.
The results showed that vitamin K1 significantly slowed the progression of coronary artery calcifications by 55%, compared to the placebo group. This finding suggests vitamin K1 may offer an important benefit in managing heart health for those with chronic kidney disease.
The results showed that vitamin K1 significantly slowed the progression of coronary artery calcifications by 55%, compared to the placebo group. This finding suggests vitamin K1 may offer an important benefit in managing heart health for those with chronic kidney disease.
References
- Liporace IL, Oliveira GBF, Alves LBO, Galassi NM, Jeronimo AD, et al. Incidence and Predictors of Clinical Outcomes in Patients with Valvular and Nonvalvular Atrial Fibrillation Using Vitamin K Antagonists. Arq Bras Cardiol. 2025;122:e20240147. doi:10.36660/abc.20240147
- Schipper JH, Sommer AS, Nies RJ, Metze C, Meertens MM, et al. Direct Oral Anticoagulants Versus Vitamin K Antagonists After Mitral Valve Transcatheter Edge-to-Edge Repair in Patients With Atrial Fibrillation: A Single-Center Observational Study. J Am Heart Assoc. 2025;14:e038834. doi:10.1161/JAHA.124.038834
- Babadagli HE, Ye J, Chen J, Turgeon R, Wang EH. Efficacy and safety of anti-thrombotic therapy after surgical mitral valve repair: a scoping review. Open Heart. 2025;12. doi:10.1136/openhrt-2024-003158
- Himmelreich JCL, Virdone S, Camm AJ, Pieper K, Harskamp RE, et al. Emulation of ARISTOTLE and ROCKET AF trials in real-world atrial fibrillation patients results in similar efficacy and safety as original landmark trials: insights from the GARFIELD-AF registry. Open Heart. 2025;12. doi:10.1136/openhrt-2024-002966
- Macias-Cervantes HE, Ocampo-Apolonio MA, Guardado-Mendoza R, Baron-Manzo M, Pereyra-Nobara TA, et al. Effect of vitamin K1 supplementation on coronary calcifications in hemodialysis patients: a randomized controlled trial. J Nephrol. 2025;38:511. doi:10.1007/s40620-024-02154-9
- Preda A, Falasconi G, Melillo F, Margonato D, Posteraro GA, et al. Left atrial appendage closure in patients with failure of anticoagulation therapy: A multicenter comparative study on the hybrid strategy using DOACs and VKAs. Int J Cardiol. 2025;421:132875. doi:10.1016/j.ijcard.2024.132875
