Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.1
USERS' SCORE
Excellent
Based on 10 Reviews
9
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Vitamin B12 (as Methylcobalamin)
1,500 mcg
62500%

Top Medical Research Studies

9
We observed how vitamin B12 deficiency can masquerade as serious conditions like hematologic malignancies, causing symptoms such as dizziness, nausea, and leukopenia. In our evaluation of a 39-year-old male, we found that treating severe B12 deficiency led to significant improvement in his blood counts.

After intensive vitamin B12 injections, his symptoms, including nausea, diminished, demonstrating the importance of assessing nutritional deficiencies before pursuing more invasive diagnoses. This case highlights how addressing vitamin B12 deficiency can effectively resolve challenging medical scenarios.
Read More
9.5
We explored the possible link between vitamin B12 deficiency and nausea in a 62-year-old patient with Type 2 Diabetes Mellitus who had been on metformin for four years. After presenting with nausea, vomiting, and other symptoms, a diagnosis of megaloblastic anemia due to vitamin B12 deficiency was made. Remarkably, the patient's symptoms alleviated following vitamin B12 injections. This case suggests the importance of monitoring B12 levels to combat related nausea in those on metformin and mitigate anemia risks.
Read More
We created a novel GLP-1 receptor agonist combined with a vitamin B12 precursor to enhance blood sugar control while minimizing nausea and vomiting. The study involved testing our Cbi-Ex4 compound in musk shrews, which are known to experience these side effects.

The results showed that Cbi-Ex4 not only provided better glycemic responses but also significantly reduced emetic events compared to traditional treatments. This encourages the potential clinical use of Cbi-Ex4, offering hope for patients who currently struggle with nausea from existing diabetes medications.
Read More

Most Useful Reviews

9.5
Nausea alleviated
I take 1 capsule each morning and evening for carpal tunnel syndrome. It used to be numb when I woke up, and I often felt numb during the day. Nausea was alleviated after about two weeks of taking it. I am mindful of light stretching and would like to continue taking more.
Read More
10
No nausea felt
I do not feel any nausea when I take this product!
Read More
9.5
No nausea issues
The capsules are nice and small. I've never experienced nausea or heartburn as I do with some other supplements. My energy and focus improve significantly when I supplement my meatless diet with this.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.1
  • All Researches
9.5
We explored the possible link between vitamin B12 deficiency and nausea in a 62-year-old patient with Type 2 Diabetes Mellitus who had been on metformin for four years. After presenting with nausea, vomiting, and other symptoms, a diagnosis of megaloblastic anemia due to vitamin B12 deficiency was made. Remarkably, the patient's symptoms alleviated following vitamin B12 injections. This case suggests the importance of monitoring B12 levels to combat related nausea in those on metformin and mitigate anemia risks.
Read More
9
We observed how vitamin B12 deficiency can masquerade as serious conditions like hematologic malignancies, causing symptoms such as dizziness, nausea, and leukopenia. In our evaluation of a 39-year-old male, we found that treating severe B12 deficiency led to significant improvement in his blood counts.

After intensive vitamin B12 injections, his symptoms, including nausea, diminished, demonstrating the importance of assessing nutritional deficiencies before pursuing more invasive diagnoses. This case highlights how addressing vitamin B12 deficiency can effectively resolve challenging medical scenarios.
Read More
We created a novel GLP-1 receptor agonist combined with a vitamin B12 precursor to enhance blood sugar control while minimizing nausea and vomiting. The study involved testing our Cbi-Ex4 compound in musk shrews, which are known to experience these side effects.

The results showed that Cbi-Ex4 not only provided better glycemic responses but also significantly reduced emetic events compared to traditional treatments. This encourages the potential clinical use of Cbi-Ex4, offering hope for patients who currently struggle with nausea from existing diabetes medications.
Read More
We observed how the B12-Ex4 conjugate may be a game-changer in managing type 2 diabetes. It effectively improved glucose tolerance in male rats without causing the nausea and malaise commonly associated with its unconjugated counterpart, Ex4.

In our study, we tested both the conjugate and Ex4 on food intake, weight, and nausea, noting that B12-Ex4 did not penetrate the brain as much, which could explain the reduced side effects.

Overall, our findings suggest that B12-Ex4 could be a promising therapeutic option, minimizing unwanted nausea while enhancing glucose management.
Read More
We examined a case of a 28-year-old man who experienced persistent headaches, nausea, and vomiting, ultimately diagnosed with cerebral venous thrombosis (CVT). This condition was linked to a mutation in the MTHFR gene and resulted in elevated homocysteine levels.

After treatment with heparin, warfarin, and vitamin B12, the patient showed significant improvement in symptoms.

This underscores the importance of screening for MTHFR mutations in patients with CVT.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 10 Reviews
9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Nausea alleviated
I take 1 capsule each morning and evening for carpal tunnel syndrome. It used to be numb when I woke up, and I often felt numb during the day. Nausea was alleviated after about two weeks of taking it. I am mindful of light stretching and would like to continue taking more.
Read More
10
No nausea felt
I do not feel any nausea when I take this product!
Read More
9.5
No nausea issues
The capsules are nice and small. I've never experienced nausea or heartburn as I do with some other supplements. My energy and focus improve significantly when I supplement my meatless diet with this.
Read More
9.5
Convenient without nausea
These capsules effectively raise B12 levels and are small and convenient to take. They do not cause nausea or irritate my stomach. I highly recommend them!
Read More
9.5
Nausea reduced
I have a clean composition and the capsules are easy to swallow. After just two weeks of taking them to address insulin resistance, I’ve noticed increased energy, reduced snacking, and fewer cravings. Nausea and headaches have decreased, and I feel calmer. I recommend this supplement for metabolism improvement.
Read More

Frequently Asked Questions

Nausea is a sensation that often precedes vomiting and is characterized by an uneasy feeling in the stomach. It can be caused by a variety of factors, including motion sickness, certain medications, food poisoning, or underlying health conditions. The experience of nausea can range from mildly uncomfortable to intensely distressing and is often accompanied by other symptoms such as sweating, increased salivation, or a feeling of lightheadedness.

Many people experience nausea at some point in their lives, making it a common issue. Fortunately, there are several remedies and treatments available that can help alleviate this unpleasant sensation. Over-the-counter medications, home remedies like ginger tea, and lifestyle changes, such as eating smaller meals or avoiding certain triggers, can be effective in reducing nausea. However, if nausea is persistent or accompanied by severe symptoms like severe abdominal pain or fever, it’s essential to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a crucial role in several vital functions in the human body. It is essential for red blood cell formation, neurological function, and DNA synthesis. Naturally occurring in animal products, the vitamin can be found in high concentrations in meat, fish, eggs, and dairy, making it particularly important for those following a vegetarian or vegan diet, as plant-based sources of B12 are limited and often require supplementation.

A deficiency in vitamin B12 can lead to serious health issues, including anemia, fatigue, memory problems, and nerve damage. Due to its significance, it's crucial for individuals, particularly those at risk of deficiency, to ensure adequate intake through diet or supplementation. For most adults, the recommended daily allowance (RDA) is around 2.4 micrograms, though pregnant or breastfeeding women may require higher amounts. If you're considering B12 supplements, it's advisable to consult with a healthcare provider to determine the best option for your specific needs and health status.

Based on user reviews, the time it takes to see results from this supplement for nausea can vary, but many users report noticeable improvements within a couple of weeks. For example, one user mentioned that their nausea was alleviated after about two weeks of consistent use of the capsules (Read Review). Other reviews indicate that users have experienced significant benefits, including the cessation of nausea and headaches, after only 10 days of use (Read Review).

Overall, while experiences may differ, it seems that two weeks may be a reasonable timeframe to expect the onset of relief from nausea for most users. It's worth noting that a number of reviews emphasized that the supplement did not induce nausea for them, suggesting overall tolerability (Read Review)(Read Review). As always, individual results may vary.

Vitamin B12 has shown potential benefits in alleviating nausea symptoms, particularly in cases of deficiency. Research indicates that addressing vitamin B12 deficiency can significantly improve nausea symptoms alongside other health issues. For example, in a case study of a patient with severe B12 deficiency, treatment with cyanocobalamin injections led to a notable decrease in nausea, emphasizing the importance of diagnosing and treating such deficiencies effectively [1]. Similar findings were observed in other contexts, where individuals with B12 deficiency experienced relief from nausea after receiving appropriate supplementation [4].

Moreover, innovative treatments combining vitamin B12 with other compounds have also been examined for their potential to reduce nausea while improving overall health outcomes. One study reported that a new GLP-1 receptor agonist combined with a B12 precursor not only provided better glycemic control but also significantly reduced the occurrence of nausea typically associated with diabetes treatments [3]. This suggests a promising avenue for future research focused on vitamin B12 and its applications for nausea management, especially related to underlying deficiencies or as part of more complex therapeutic strategies. However, while evidence points to the efficacy of vitamin B12 in specific scenarios, further research is necessary to delineate its effectiveness as a standalone remedy for nausea.

Based on user reviews, many individuals have reported improvements in various symptoms after using the supplement. Several users specifically noted the alleviation of nausea, with one stating that they no longer experienced nausea after consistent use of the product (Read Review). Another user mentioned that nausea and headaches ceased after just 10 days of taking the capsules (Read Review). Furthermore, one reviewer highlighted that after two weeks of use for insulin resistance, they noticed a reduction in cravings, headaches, and an overall calming effect (Read Review).

In addition to nausea relief, many users have experienced boosts in energy, focus, and mood. A common sentiment among reviewers is the product's tolerability, as several indicated that it does not induce nausea or stomach discomfort, which is often an issue with other supplements (Read Review). While individual results can vary significantly, the feedback suggests that this supplement may offer substantial benefits, particularly regarding nausea management and enhanced overall well-being.

Users report positive experiences when combining this supplement with other vitamins for handling nausea. Many have noted the product's tolerability, emphasizing that it does not induce nausea or stomach discomfort, which is often a problem with various supplements. For instance, one reviewer specifically stated that they take this supplement alongside other vitamins and appreciate its lack of nausea-inducing effects, highlighting its compatibility with their routine (Read Review).

Furthermore, another user remarked on the absence of nausea and heartburn compared to other supplements, thus reinforcing the supplement's favorable tolerability even when integrated with different dietary additions (Read Review). Overall, the feedback indicates that this product can be safely combined with other supplements, making it a versatile addition to those seeking effective nausea relief and overall wellness support.

Based on user reviews, many individuals report positive experiences regarding the consumption of B12 for alleviating nausea. A frequent observation is that those who take B12 regularly do not experience nausea; for instance, one user mentioned, "I do not feel any nausea when I take this product!" (Read Review). Others noted that after a few weeks of consistent use, nausea and headaches significantly reduced—perhaps indicating that a longer duration of intake might be beneficial in managing these symptoms. One user shared their experience, stating that nausea was alleviated after about two weeks of taking a B12 supplement alongside other health measures (Read Review).

In terms of dosage, while specific amounts were not commonly emphasized across the reviews, the general consensus suggests that regular intake—whether one capsule or more—tends to yield favorable results without adverse effects such as nausea. Several reviews highlighted that the capsules are small and easy to swallow, further contributing to their positive reception. Many users noted that they could tolerate the product well, particularly compared to other vitamins that typically induce nausea (Read Review). Overall, users appear to find that appropriate B12 supplementation not only helps alleviate nausea but may also enhance energy and well-being.

9.5
Nausea alleviated
I take 1 capsule each morning and evening for carpal tunnel syndrome. It used to be numb when I woke up, and I often felt numb during the day. Nausea was alleviated after about two weeks of taking it. I am mindful of light stretching and would like to continue taking more.
9.5
Nausea ceased
Very satisfied with the fast delivery. The capsules are small and convenient when swallowed, with a neutral taste. I've experienced significant benefits in energy and mood after 10 days. Headaches and nausea have stopped, and my metabolism has improved. Highly recommended!
9.5
Convenient without nausea
These capsules effectively raise B12 levels and are small and convenient to take. They do not cause nausea or irritate my stomach. I highly recommend them!
9.5
Nausea avoided
Recommended by my doctor, I take it along with other vitamins. This product is well tolerated, especially as some vitamins typically cause nausea. I find these great!
10
No nausea felt
I do not feel any nausea when I take this product!
9.5
Nausea reduced
I have a clean composition and the capsules are easy to swallow. After just two weeks of taking them to address insulin resistance, I’ve noticed increased energy, reduced snacking, and fewer cravings. Nausea and headaches have decreased, and I feel calmer. I recommend this supplement for metabolism improvement.
9.5
No nausea issues
The capsules are nice and small. I've never experienced nausea or heartburn as I do with some other supplements. My energy and focus improve significantly when I supplement my meatless diet with this.
We explored the impact of vitamin B12 deficiency on symptoms, including nausea, through a case study of a 60-year-old woman. When she presented with weakness, dizziness, and abdominal pain, lab tests revealed severe vitamin B12 deficiency linked to pernicious anemia.

After receiving treatment with intramuscular cyanocobalamin injections, her overall health improved significantly. This case highlights the importance of diagnosing vitamin B12 deficiency not only for its hematologic effects but also for alleviating symptoms like nausea. Early recognition is key to effective management.
9.5
We explored the possible link between vitamin B12 deficiency and nausea in a 62-year-old patient with Type 2 Diabetes Mellitus who had been on metformin for four years. After presenting with nausea, vomiting, and other symptoms, a diagnosis of megaloblastic anemia due to vitamin B12 deficiency was made. Remarkably, the patient's symptoms alleviated following vitamin B12 injections. This case suggests the importance of monitoring B12 levels to combat related nausea in those on metformin and mitigate anemia risks.
We examined a case of a 20-year-old woman with type 1 diabetes who experienced symptoms like diarrhea and nausea due to autoimmune gastritis. Despite no initial signs of vitamin B12 deficiency, she was given B12 supplements. Remarkably, this treatment led to improvements in both her gastrointestinal and neurological problems.

This highlights the importance of recognizing underlying autoimmune disorders in diabetes patients and considering B12 therapy, even if deficiency isn't present. Understanding these connections may help prevent further complications down the line.

References

  1. Salimiaghdam N, Jumaah O, Acob T, Hakobyan K, Chen E. Vitamin B12 Deficiency in Pernicious Anemia: A Hemolytic Anemia Mimic. Cureus. 2025;17:e79176. doi:10.7759/cureus.79176
  2. Choi E, Galicia Garcia G, Kishore Anna K, Albuja Altamirano MF, Yip L, et al. Vitamin B12 Deficiency Manifesting As Pancytopenia, Lymphadenopathy, and Fever: A Clinical Mimic of Hematologic Malignancies. Cureus. 2024;16:e64676. doi:10.7759/cureus.64676
  3. Meyers TM, Reeves PT, Lombardo JL, Anisowicz SK, Larson NS, et al. Autoimmune gastritis as an unexpected cause of diarrhea in a young adult with type I diabetes: a case report. J Med Case Rep. 2023;17:342. doi:10.1186/s13256-023-04039-0
  4. Albai O, Timar B, Paun DL, Sima A, Roman D, et al. Metformin Treatment: A Potential Cause of Megaloblastic Anemia in Patients with Type 2 Diabetes Mellitus. Diabetes Metab Syndr Obes. 2020;13:3873. doi:10.2147/DMSO.S270393
  5. Borner T, Workinger JL, Tinsley IC, Fortin SM, Stein LM, et al. Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis. Cell Rep. 2020;31:107768. doi:10.1016/j.celrep.2020.107768
  6. Mietlicki-Baase EG, Liberini CG, Workinger JL, Bonaccorso RL, Borner T, et al. A vitamin B12 conjugate of exendin-4 improves glucose tolerance without associated nausea or hypophagia in rodents. Diabetes Obes Metab. 2018;20:1223. doi:10.1111/dom.13222
  7. Dikici S, Saritas A, Besir FH, Celbek G, Arslan G. May headache be the first sign of mutation in the MTHFR gene?. World J Emerg Med. 2013;4:69.
  8. Dikici S, Saritas A, Besir FH, Celbek G, Arslan G. May headache be the first sign of mutation in the MTHFR gene?. World J Emerg Med. 2013;4:69.
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