Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Good
Based on 13 Reviews
8.3
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Vitamin B12 (as Methylcobalamin)
1,500 mcg
62500%

Top Medical Research Studies

5
B12 and ALA assist nerve recovery
We explored the effects of Vitamin B12 and alpha lipoic acid (ALA) on nerve recovery in a rat model of sciatic nerve injury.

Through a rigorous study design involving 40 rats divided into different treatment groups, we assessed functional recovery using various analyses.

Interestingly, while both treatments yielded positive results, ALA showed greater functional improvements compared to B12.

Overall, B12 was effective in enhancing myelination and reducing edema, highlighting its unique benefits alongside ALA’s advantages.
Read More
9
Vitamin B12 effective for back pain
We explored the effectiveness of intramuscular Vitamin B12 for treating low back pain, particularly in those with mechanical sciatica. In a well-structured study involving 60 participants, patients received either Vitamin B12 or a placebo, and we measured pain and disability levels.

By the end of the study, those receiving Vitamin B12 showed a significant decrease in both pain and disability compared to the placebo group. Moreover, they relied less on pain relief medication, indicating that B12 could be a beneficial option for addressing persistent back pain.
Read More
8
Dietary supplement boosts pain relief
We explored the impact of a novel dietary supplement on patients undergoing percutaneous laser disc decompression for lumbar disc herniation.

Patients were divided into two groups: one received just the laser treatment while the other added the supplement.

While both groups reported reduced pain levels post-surgery, the supplement group experienced slightly better outcomes.

Most patients using the supplement noted improved leg pain, with 66.5% reporting significant relief. However, it’s important to mention that the supplement's additional benefits weren’t groundbreaking compared to the laser treatment alone.
Read More

Most Useful Reviews

10
Pain relief achieved
29 people found this helpful
It has been 7 months since I began taking vitamin B12 for my sciatica, which was initially so severe that I couldn't walk. After 4 months, the pain had almost disappeared, and now I feel no pain at all. I used to suffer from this hernia-related pain every day for nearly two years. I still take it daily after meals, as it’s a small capsule that's easy to swallow. I highly recommend it for anyone dealing with nerve pain!
Read More
9
Improved symptoms noted
4 people found this helpful
I have suffered from sciatica due to spinal stenosis for over six months. Over-the-counter medications did not help. Upon starting this supplement, my symptoms improved significantly. The numbness and pain in my calf have nearly gone, leading to a more positive mood. The cute pink capsules make me feel better every time I take one.
Read More
9
Significant pain relief
3 people found this helpful
The mother suffers from sciatica, and I am grateful for the significant improvement and pain relief she's experienced. The package size is perfect, and the number of capsules is plentiful. The taste and smell are acceptable, and I find the effectiveness to be excellent and noticeable.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
  • All Researches
9
Vitamin B12 effective for back pain
We explored the effectiveness of intramuscular Vitamin B12 for treating low back pain, particularly in those with mechanical sciatica. In a well-structured study involving 60 participants, patients received either Vitamin B12 or a placebo, and we measured pain and disability levels.

By the end of the study, those receiving Vitamin B12 showed a significant decrease in both pain and disability compared to the placebo group. Moreover, they relied less on pain relief medication, indicating that B12 could be a beneficial option for addressing persistent back pain.
Read More
8
Dietary supplement boosts pain relief
We explored the impact of a novel dietary supplement on patients undergoing percutaneous laser disc decompression for lumbar disc herniation.

Patients were divided into two groups: one received just the laser treatment while the other added the supplement.

While both groups reported reduced pain levels post-surgery, the supplement group experienced slightly better outcomes.

Most patients using the supplement noted improved leg pain, with 66.5% reporting significant relief. However, it’s important to mention that the supplement's additional benefits weren’t groundbreaking compared to the laser treatment alone.
Read More
8
Vitamin B12 aids post-surgery recovery
We evaluated the effectiveness of a unique “cocktail treatment,” containing ropivacaine, dexamethasone, and vitamin B12, after percutaneous endoscopic lumbar discectomy (PELD). In our retrospective study at Hong-Hui Hospital, we compared results from 100 patients—50 received the treatment while the other 50 did not.

The findings indicated that this cocktail significantly improved both back and leg pain relief, as well as enhanced functional recovery for those who received it. While promising, we acknowledge the study's single-center design and lack of randomization as limitations.
Read More
5
B12 and ALA assist nerve recovery
We explored the effects of Vitamin B12 and alpha lipoic acid (ALA) on nerve recovery in a rat model of sciatic nerve injury.

Through a rigorous study design involving 40 rats divided into different treatment groups, we assessed functional recovery using various analyses.

Interestingly, while both treatments yielded positive results, ALA showed greater functional improvements compared to B12.

Overall, B12 was effective in enhancing myelination and reducing edema, highlighting its unique benefits alongside ALA’s advantages.
Read More

User Reviews

USERS' SCORE
Good
Based on 13 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Pain relief achieved
29 people found this helpful
It has been 7 months since I began taking vitamin B12 for my sciatica, which was initially so severe that I couldn't walk. After 4 months, the pain had almost disappeared, and now I feel no pain at all. I used to suffer from this hernia-related pain every day for nearly two years. I still take it daily after meals, as it’s a small capsule that's easy to swallow. I highly recommend it for anyone dealing with nerve pain!
Read More
9
Improved symptoms noted
4 people found this helpful
I have suffered from sciatica due to spinal stenosis for over six months. Over-the-counter medications did not help. Upon starting this supplement, my symptoms improved significantly. The numbness and pain in my calf have nearly gone, leading to a more positive mood. The cute pink capsules make me feel better every time I take one.
Read More
9
Significant pain relief
3 people found this helpful
The mother suffers from sciatica, and I am grateful for the significant improvement and pain relief she's experienced. The package size is perfect, and the number of capsules is plentiful. The taste and smell are acceptable, and I find the effectiveness to be excellent and noticeable.
Read More
7.5
Comfortable experience
1 people found this helpful
I began taking this supplement after hearing it helps repair peripheral nerves. I definitely notice a difference; my severe sciatica feels much more manageable. This supplement has become essential for me.
Read More
7.5
Effective for sciatica
I purchased this for my husband, who suffers from heat in his feet and sciatica. He has found it helpful. Thank goodness for this product!
Read More

Frequently Asked Questions

10
Pain relief achieved
29 people found this helpful
It has been 7 months since I began taking vitamin B12 for my sciatica, which was initially so severe that I couldn't walk. After 4 months, the pain had almost disappeared, and now I feel no pain at all. I used to suffer from this hernia-related pain every day for nearly two years. I still take it daily after meals, as it’s a small capsule that's easy to swallow. I highly recommend it for anyone dealing with nerve pain!
7.5
Comfortable experience
1 people found this helpful
I began taking this supplement after hearing it helps repair peripheral nerves. I definitely notice a difference; my severe sciatica feels much more manageable. This supplement has become essential for me.
6
Minimal effect noted
I take vitamin B12 for my sciatica, though I don’t feel a significant effect. However, it’s affordable and easy to continue taking.
9
Improved symptoms noted
4 people found this helpful
I have suffered from sciatica due to spinal stenosis for over six months. Over-the-counter medications did not help. Upon starting this supplement, my symptoms improved significantly. The numbness and pain in my calf have nearly gone, leading to a more positive mood. The cute pink capsules make me feel better every time I take one.
9
Significant pain relief
3 people found this helpful
The mother suffers from sciatica, and I am grateful for the significant improvement and pain relief she's experienced. The package size is perfect, and the number of capsules is plentiful. The taste and smell are acceptable, and I find the effectiveness to be excellent and noticeable.
7.5
Uncertain effectiveness
6 people found this helpful
I bought this twice for my husband, who had numbness in his hands and sciatica. He didn't finish it, but I noticed improvement in his symptoms over time. While I'm uncertain of its effects personally, I think it's a good supplement, especially for neurological symptoms, and it's inexpensive.
7.5
Improved condition noted
I decided to continue using this supplement after it seemed to help me more than the medication prescribed for my sciatica. I look forward to seeing continued improvement.
9
Vitamin B12 effective for back pain
We explored the effectiveness of intramuscular Vitamin B12 for treating low back pain, particularly in those with mechanical sciatica. In a well-structured study involving 60 participants, patients received either Vitamin B12 or a placebo, and we measured pain and disability levels.

By the end of the study, those receiving Vitamin B12 showed a significant decrease in both pain and disability compared to the placebo group. Moreover, they relied less on pain relief medication, indicating that B12 could be a beneficial option for addressing persistent back pain.
5
B12 and ALA assist nerve recovery
We explored the effects of Vitamin B12 and alpha lipoic acid (ALA) on nerve recovery in a rat model of sciatic nerve injury.

Through a rigorous study design involving 40 rats divided into different treatment groups, we assessed functional recovery using various analyses.

Interestingly, while both treatments yielded positive results, ALA showed greater functional improvements compared to B12.

Overall, B12 was effective in enhancing myelination and reducing edema, highlighting its unique benefits alongside ALA’s advantages.

References

  1. Gazzeri R, Leoni MLG, Occhigrossi F. Efficacy of Percutaneous Laser Disc Decompression (PLDD) Combined with an Oral Food Supplement for Lumbar Disc Herniation. J Clin Med. 2024;13. doi:10.3390/jcm13175049
  2. Yang JS, Liu KX, Chu L, Chan YK, Fan H, et al. Cocktail Treatment with a Gelatin Sponge Impregnated with Ropivacaine, Dexamethasone, and Vitamin B12 Promotes Early Postoperative Recovery after Percutaneous Endoscopic Lumbar Discectomy: A Retrospective, Case-Controlled Study. Pain Physician. 2020;23:E211.
  3. Horasanli B, Hasturk AE, Arikan M, Togral G, Helvacioglu F, et al. Comparative evaluation of the electrophysiological, functional and ultrastructural effects of alpha lipoic acid and cyanocobalamin administration in a rat model of sciatic nerve injury. J Back Musculoskelet Rehabil. 2017;30:967. doi:10.3233/BMR-150386
  4. Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4:53.
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