Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.8
Supplement Facts
Serving Size: 3 Capsules
Serving Per Container: 120
Amount Per Serving
%DV
MSM (Methylsulfonylmethane) (OptiMSM®)
3,000 mg

Top Medical Research Studies

We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More

Most Useful Reviews

9
Alleviated discomfort
2 people found this helpful
This supplement works wonders for joint discomfort. I bought it for my mum after her minor osteoarthritis diagnosis, and now she no longer feels discomfort in her knees. I’ve since ordered a stronger version, 1500 mg, which continues to prove effective.
Read More
9
Enhanced joint mobility
1 people found this helpful
I ordered MSM alongside Glucosamine and Chondroitin. This natural sulphur compound contributes to healthy connective tissue and aids in maintaining joint health and mobility. I noticed benefits right away; my fingers bend more easily, and I experience less fatigue from walking long distances. The large packaging lasts a long time, and I am pleased with the results.
Read More
9
Gym recovery
1 people found this helpful
After experiencing joint problems from gym workouts, I decided to try this supplement. Within two months, I experienced marked improvement and returned to the gym without any joint issues. I highly recommend this product for joint health and plan to take it every six months for preventative measures.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 14 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Alleviated discomfort
2 people found this helpful
This supplement works wonders for joint discomfort. I bought it for my mum after her minor osteoarthritis diagnosis, and now she no longer feels discomfort in her knees. I’ve since ordered a stronger version, 1500 mg, which continues to prove effective.
Read More
9
Enhanced joint mobility
1 people found this helpful
I ordered MSM alongside Glucosamine and Chondroitin. This natural sulphur compound contributes to healthy connective tissue and aids in maintaining joint health and mobility. I noticed benefits right away; my fingers bend more easily, and I experience less fatigue from walking long distances. The large packaging lasts a long time, and I am pleased with the results.
Read More
9
Gym recovery
1 people found this helpful
After experiencing joint problems from gym workouts, I decided to try this supplement. Within two months, I experienced marked improvement and returned to the gym without any joint issues. I highly recommend this product for joint health and plan to take it every six months for preventative measures.
Read More
7.5
Joint improvement
154 people found this helpful
Super!!!!! I want to leave my honest review about this drug I ordered for my mum. My mum had joint problems and couldn’t raise her left arm. After being diagnosed with supraspinatus tendinosis, I started her on this supplement. Initially, she struggled to raise her hand, but now there have been positive changes. She can raise and lower her arm and even stretches. I recommend this to anyone with joint issues. If my review was helpful, please click YES. Thanks! Wishing everyone good health!
Read More
7.5
Effective joint treatment
6 people found this helpful
I have been taking MSM for years with fantastic results. I ordered this for my granddaughter, and she confirms it works for her too. I first learned about MSM in the 70s when a vet recommended it for my horse; now we give it to people. It takes time but is truly effective; even my older dogs are now taking it. I'm a believer—thank you!
Read More

Frequently Asked Questions

7.5
Joint pain relief
1 people found this helpful
I love this supplement! My husband has joint issues and takes it every six months. After a few weeks, he feels much better. I also began taking it as my back and shoulder pain decreased. I even got half the employees at work to order it after sharing the results—everyone is very pleased. I recommend it for prevention, taking one tablet, while my husband with specific issues takes two daily.
9
Gym recovery
1 people found this helpful
After experiencing joint problems from gym workouts, I decided to try this supplement. Within two months, I experienced marked improvement and returned to the gym without any joint issues. I highly recommend this product for joint health and plan to take it every six months for preventative measures.
7.5
Effective joint treatment
6 people found this helpful
I have been taking MSM for years with fantastic results. I ordered this for my granddaughter, and she confirms it works for her too. I first learned about MSM in the 70s when a vet recommended it for my horse; now we give it to people. It takes time but is truly effective; even my older dogs are now taking it. I'm a believer—thank you!
9
Alleviated discomfort
2 people found this helpful
This supplement works wonders for joint discomfort. I bought it for my mum after her minor osteoarthritis diagnosis, and now she no longer feels discomfort in her knees. I’ve since ordered a stronger version, 1500 mg, which continues to prove effective.
7.5
Joint improvement
154 people found this helpful
Super!!!!! I want to leave my honest review about this drug I ordered for my mum. My mum had joint problems and couldn’t raise her left arm. After being diagnosed with supraspinatus tendinosis, I started her on this supplement. Initially, she struggled to raise her hand, but now there have been positive changes. She can raise and lower her arm and even stretches. I recommend this to anyone with joint issues. If my review was helpful, please click YES. Thanks! Wishing everyone good health!
9
Hair and nails
4 people found this helpful
I ordered Best MSM for hair growth and took it for three months with noteworthy results: my hair became stronger, shinier, and grew faster, while my nails also improved significantly and became less prone to breakage.
0
Strange symptoms experienced
I will not order this again! The product gives me unusual symptoms. I have tried to skip taking it for a few days, and the symptoms disappear.
9
Enhanced joint mobility
1 people found this helpful
I ordered MSM alongside Glucosamine and Chondroitin. This natural sulphur compound contributes to healthy connective tissue and aids in maintaining joint health and mobility. I noticed benefits right away; my fingers bend more easily, and I experience less fatigue from walking long distances. The large packaging lasts a long time, and I am pleased with the results.
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.

References

  1. Arlt FA, Miske R, Machule ML, Broegger Christensen P, Mindorf S, et al. KCNA2 IgG autoimmunity in neuropsychiatric diseases. Brain Behav Immun. 2024;117:399. doi:10.1016/j.bbi.2024.01.220
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