Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.2
USERS' SCORE
Good
Based on 6 Reviews
8.3
Supplement Facts
Serving Size: 2 Marine Softgels
Amount Per Serving
%DV
Calories
20
 
Total Fat
2 g
3%**
Fish Oil ConcentrateTotal Omega-3 Fatty Acids as Ethyl EstersEPA (EicosaPentaenoic Acid), min.DHA (DocosaHexaenoic Acid), min.
2000 mg1400 mg800 mg400 mg
††††

Top Medical Research Studies

9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
8
Omega-3s reduce headache frequency
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.

Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.

Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.

While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.

This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Read More

Most Useful Reviews

9
Energy boost
Good composition, quick delivery, high-quality packaging with no damage. The capsules are a bit large, but easy to swallow, and taste like citrus. I take one daily with meals alongside vitamin D3+K2 and magnesium. After 10 days, I’ve noticed benefits; my frequent headaches, nausea, and fatigue have ceased. I’m more energised and my mood is excellent. Perfect for those into sports or on a diet. Omega-3 truly revitalises the body!
Read More
9
Mood enhancement
Great! This is the best Omega-3 I've tried so far. I can feel the effects—I feel energised, have no headaches, and my appetite is good. I was prescribed this dosage for three months, then to reduce it to 1000mg daily.
Read More
7.5
Reduced headaches
5 people found this helpful
Wonderful! This is not the first time I've ordered this Omega-3; it's fantastic! I take one capsule daily as I have high cholesterol. Since starting this Omega, I've felt much better! My headaches have lessened, and my blood pressure is stable. I also give one to my 17-year-old son for prevention. They are easy to swallow despite their size, with no fishy aftertaste. I highly recommend this Omega-3!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.2
  • All Researches
9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
9
Omega-3 diet improves headaches
We examined how adjusting omega-3 and omega-6 fatty acids influences chronic headaches and overall well-being. In a randomized trial with 67 participants suffering from severe headaches, those who increased omega-3 intake while decreasing omega-6 saw significant improvements in their headaches and reductions in psychological distress.

Over 12 weeks, participants in this dietary intervention reported better mental and physical health, which also helped decrease the number of headache days. Overall, this approach not only targets headache relief but also enhances quality of life.
Read More
We conducted a study to understand how changes in the intake of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), can influence chronic headaches. By focusing on one group consuming a high level of omega-3 and low omega-6, while another group maintained a low omega-6 diet, we aimed to identify any significant improvements in headache symptoms over a 12-week period.

Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.

These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
Read More
8
Omega-3s reduce headache frequency
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.

Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.

Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.

While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.

This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Energy boost
Good composition, quick delivery, high-quality packaging with no damage. The capsules are a bit large, but easy to swallow, and taste like citrus. I take one daily with meals alongside vitamin D3+K2 and magnesium. After 10 days, I’ve noticed benefits; my frequent headaches, nausea, and fatigue have ceased. I’m more energised and my mood is excellent. Perfect for those into sports or on a diet. Omega-3 truly revitalises the body!
Read More
9
Mood enhancement
Great! This is the best Omega-3 I've tried so far. I can feel the effects—I feel energised, have no headaches, and my appetite is good. I was prescribed this dosage for three months, then to reduce it to 1000mg daily.
Read More
7.5
Reduced headaches
5 people found this helpful
Wonderful! This is not the first time I've ordered this Omega-3; it's fantastic! I take one capsule daily as I have high cholesterol. Since starting this Omega, I've felt much better! My headaches have lessened, and my blood pressure is stable. I also give one to my 17-year-old son for prevention. They are easy to swallow despite their size, with no fishy aftertaste. I highly recommend this Omega-3!
Read More
7.5
Skin improvement
Pure oil from South Pacific anchovies. I frequently order Omega-3 as it alleviates my headaches and improves my skin's smoothness and hydration. Additionally, it supports heart, eye, and joint health.
Read More
7.5
Pain relief
For many years, I've struggled with musculoskeletal issues, but after starting Fitoliton extract, I’ve experienced great relief. Although I had some pain initially as the stone passed, now my heart no longer hurts, my sleep has improved, and my headaches have disappeared. It’s wonderful that such beneficial products exist with a pleasant taste!
Read More

Frequently Asked Questions

9
Energy boost
Good composition, quick delivery, high-quality packaging with no damage. The capsules are a bit large, but easy to swallow, and taste like citrus. I take one daily with meals alongside vitamin D3+K2 and magnesium. After 10 days, I’ve noticed benefits; my frequent headaches, nausea, and fatigue have ceased. I’m more energised and my mood is excellent. Perfect for those into sports or on a diet. Omega-3 truly revitalises the body!
7.5
Reduced headaches
5 people found this helpful
Wonderful! This is not the first time I've ordered this Omega-3; it's fantastic! I take one capsule daily as I have high cholesterol. Since starting this Omega, I've felt much better! My headaches have lessened, and my blood pressure is stable. I also give one to my 17-year-old son for prevention. They are easy to swallow despite their size, with no fishy aftertaste. I highly recommend this Omega-3!
9
Mood enhancement
Great! This is the best Omega-3 I've tried so far. I can feel the effects—I feel energised, have no headaches, and my appetite is good. I was prescribed this dosage for three months, then to reduce it to 1000mg daily.
7.5
Effective relief
I really liked this Omega-3. I had headaches previously, but now it's brilliant! I also take vitamin D3, and I'm very pleased with the results. Thank you very much!
7
EPA supplementation may reduce migraines
We conducted a randomized, placebo-controlled trial to explore the effects of daily 2000 mg of eicosapentaenoic acid (EPA) on chronic migraines. Over 8 weeks, participants recorded their headache symptoms, with some taking EPA and others receiving a placebo.

Our findings suggest that EPA may significantly reduce the frequency of migraine attacks and improve overall quality of life for chronic migraine sufferers. However, we believe that more research is needed for a clearer understanding of its benefits and dosage.
9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
8
Eicosapentaenoic acid reduces migraine
We aimed to understand how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, may influence the frequency of migraine attacks among individuals suffering from this debilitating condition. In our study, we assessed 105 migraine patients aged between 15 and 50 years. Participants provided information about their typical dietary habits through a food frequency questionnaire, and we recorded the number of migraine attacks they experienced over a month.

Our findings were enlightening; we observed that lower intake of EPA was linked to a higher frequency of migraine attacks. Specifically, the analysis revealed that as EPA consumption decreased, the number of migraine incidents increased significantly, with a beta value of -335.07 and a P-value of 0.006. Additionally, similar patterns were noted for docosahexaenoic acid (DHA), another omega-3 fatty acid, which showed a beta value of -142.51 and a P-value of 0.001.

However, we found no significant connection between saturated fatty acid intake and migraine frequency, suggesting that not all fats play a role in this context. This research indicates a compelling relationship between omega-3 intake and migraine occurrences, urging us to consider dietary adjustments as a potential strategy for managing this condition.

Further studies could build on these findings to deepen our understanding of dietary influences on migraine and explore how specific nutrients like EPA might serve as effective components in treatment plans.
We conducted a study to understand how changes in the intake of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), can influence chronic headaches. By focusing on one group consuming a high level of omega-3 and low omega-6, while another group maintained a low omega-6 diet, we aimed to identify any significant improvements in headache symptoms over a 12-week period.

Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.

These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
We set out to understand how changes in dietary fatty acids could influence headache symptoms, particularly focusing on eicosapentaenoic acid (EPA). In a 12-week study, individuals suffering from chronic headaches followed specific diets: one group reduced their omega-6 fatty acids while maintaining an average intake of omega-3s, and another group increased their omega-3 intake alongside lowering omega-6.

Our results were revealing. Reducing omega-6 fatty acids, such as linoleic acid, led to a notable increase in omega-3 levels, particularly EPA and docosahexaenoic acid (DHA), in the participants' plasma. Interestingly, while dietary changes improved omega-3 availability in the body, they did not significantly affect arachidonic acid (AA) levels, a key omega-6 fatty acid linked to inflammation.

In the group that bumped up their omega-3 intake significantly, there was an even more pronounced increase in the levels of these beneficial fatty acids. However, we did not find evidence suggesting that these changes led to a direct reduction in headache frequency or severity. This indicates that while eicosapentaenoic acid and other omega-3s may enhance bioavailability when omega-6s are lowered, they did not expressly alleviate headaches during the study period.
8
Omega-3 reduces migraine frequency
We explored the effectiveness of omega-3 fatty acids in preventing chronic migraine attacks through a well-structured double-blind study. Sixty patients diagnosed with chronic migraines were split into two groups: one received omega-3 alongside amitriptyline, while the other got a placebo.

After 60 days, we observed that 66.7% of the omega-3 group reported more than an 80% reduction in headache days, compared to only 33.3% in the control group. This shows promise for omega-3 as a migraine preventive, though further study is needed to solidify these findings.

References

  1. Yeh EL, Yang CP, Lin SW, Wang HF. Feasibility of Fish Oil Supplementation on Headache Symptoms and Blood Lipids in Migraine Patients. Brain Behav. 2024;14:e70149. 10.1002/brb3.70149
  2. Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. 10.1111/head.14808
  3. Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. 10.1016/j.bbi.2024.03.019
  4. Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. 10.1016/j.jpain.2022.10.008
  5. Faurot KR, Cole WR, MacIntosh BA, Dunlap M, Moore CB, et al. Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial. Contemp Clin Trials. 2022;119:106851. 10.1016/j.cct.2022.106851
  6. Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. 10.1136/bmj.n1448
  7. Honarvar NM, Soveid N, Abdolahi M, Djalali M, Hatami M, et al. Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano- Curcumin on Migraine Patients from Cellular to Clinical Insight: A Randomized, Double-Blind and Placebo-Controlled Trial. Endocr Metab Immune Disord Drug Targets. 2021;21:365. 10.2174/1871530320666200729144430
  8. Abdolahi M, Jafarieh A, Sarraf P, Sedighiyan M, Yousefi A, et al. The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms. Endocr Metab Immune Disord Drug Targets. 2019;19:874. 10.2174/1871530319666190212170140
  9. Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. 10.1016/j.plefa.2018.06.008
  10. Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, et al. A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol. Prostaglandins Leukot Essent Fatty Acids. 2018;128:41. 10.1016/j.plefa.2017.11.002
  11. Shen T, Xing G, Zhu J, Zhang S, Cai Y, et al. Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol. Lipids Health Dis. 2017;16:253. 10.1186/s12944-017-0617-0
  12. Soveyd N, Abdolahi M, Djalali M, Hatami M, Tafakhori A, et al. The Combined Effects of ω -3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients. CNS Neurol Disord Drug Targets. 2018;16:1120. 10.2174/1871527317666171213154749
  13. Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69:371. 10.1007/s00251-017-0992-8
  14. Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. 10.1080/1028415X.2016.1266133
  15. Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, et al. Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress. J Pain. 2015;16:707. 10.1016/j.jpain.2015.04.007
  16. Ramsden CE, Faurot KR, Zamora D, Palsson OS, MacIntosh BA, et al. Targeted alterations in dietary n-3 and n-6 fatty acids improve life functioning and reduce psychological distress among patients with chronic headache: a secondary analysis of a randomized trial. Pain. 2015;156:587. 10.1097/01.j.pain.0000460348.84965.47
  17. Sadeghi O, Maghsoudi Z, Khorvash F, Ghiasvand R, Askari G. The relationship between different fatty acids intake and frequency of migraine attacks. Iran J Nurs Midwifery Res. 2015;20:334.
  18. Taha AY, Cheon Y, Faurot KF, Macintosh B, Majchrzak-Hong SF, et al. Dietary omega-6 fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools. Prostaglandins Leukot Essent Fatty Acids. 2014;90:151. 10.1016/j.plefa.2014.02.003
  19. Ramsden CE, Faurot KR, Zamora D, Suchindran CM, MacIntosh BA, et al. Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial. Pain. 2013;154:2441. 10.1016/j.pain.2013.07.028
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