' 
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.4
USERS' SCORE
Good
Based on 20 Reviews
8.8
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg
†
Top Medical Research Studies
9
Selenium nanoparticles reduce allergies
Translational Selenium Nanoparticles to Attenuate Allergic Dermatitis through Nrf2-Keap1-Driven Activation of Selenoproteins.
Direct exploration of selenium's effects
We examined how selenium, a trace element known for its role in health, can help those suffering from allergic dermatitis. In our exploration, we focused on how selenium nanoparticles, specifically designed for easier manufacturing and use, can activate the body's natural defenses against allergies.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
Read More
9
Potential asthma management via yeast
Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice.
Moderate relevance to asthma prevention
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Read More
9
Selenium polysaccharides reduce allergies
Se-rich tea polysaccharide extracted by high hydrostatic pressure attenuated anaphylaxis by improving gut microbiota and metabolic regulation.
Study highlights selenium’s allergy potential
We explored the role of selenium-rich tea polysaccharides (Se-TPS) in managing allergies, focusing on how they influence immune responses and gut health. Using a method called high hydrostatic pressure, we extracted Se-TPS at a pressure of 400 MPa for a specific duration. This process allowed us to isolate several polysaccharide components, particularly Se-TPS3-4, which turned out to be the most effective.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Read More
Most Useful Reviews
9.5
Effective breathing aid
This helps with colds, allergies, sinus infections, and bronchitis, allowing me to breathe without side effects. Introduced to acetylcysteine during a bout of bronchitis, I was able to breathe more easily with no adverse effects from usual medications. Now, I can easily handle fall allergies and sinus issues as well, without needing Sudafed or Claritin. I take 2 a day as the maximum dose. It's incredibly beneficial and crucial for my body.
Read More
9.5
Child's improvement
It’s very effective; my child’s nose allergy has improved considerably, and he no longer coughs. The benefits include fighting free radicals and anti-oxidation, despite the slightly unpleasant smell.
Read More
9.5
Relieves sinus pressure
Incredible for sinus pressure and allergies. I'm amazed I'm off Claritin this Spring. I take it every other day; the instant I feel sinus pressure, one dose works like a miracle.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.4
- All Researches
9
Potential asthma management via yeast
Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice.
Moderate relevance to asthma prevention
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Read More
9
Selenium polysaccharides reduce allergies
Se-rich tea polysaccharide extracted by high hydrostatic pressure attenuated anaphylaxis by improving gut microbiota and metabolic regulation.
Study highlights selenium’s allergy potential
We explored the role of selenium-rich tea polysaccharides (Se-TPS) in managing allergies, focusing on how they influence immune responses and gut health. Using a method called high hydrostatic pressure, we extracted Se-TPS at a pressure of 400 MPa for a specific duration. This process allowed us to isolate several polysaccharide components, particularly Se-TPS3-4, which turned out to be the most effective.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Read More
9
Selenium nanoparticles reduce allergies
Translational Selenium Nanoparticles to Attenuate Allergic Dermatitis through Nrf2-Keap1-Driven Activation of Selenoproteins.
Direct exploration of selenium's effects
We examined how selenium, a trace element known for its role in health, can help those suffering from allergic dermatitis. In our exploration, we focused on how selenium nanoparticles, specifically designed for easier manufacturing and use, can activate the body's natural defenses against allergies.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
Read More
9
Selenium influences milk allergy response
Selenium Modulates the Allergic Response to Whey Protein in a Mouse Model for Cow's Milk Allergy.
Highly relevant to selenium and allergies
We investigated the impact of dietary selenium on cow's milk allergy, a common condition affecting infants. In our study, we used a mouse model and sensitized three-week-old female C3H/HeOuJ mice with whey protein and cholera toxin. These mice were then divided into groups and fed diets with varying levels of selenium: control, low, medium, or high.
After subjecting the mice to a whey challenge, we noted some interesting changes. Notably, the body temperature of mice on a medium selenium diet was significantly higher 60 minutes post-challenge, suggesting a less severe allergic reaction. We also observed decreased levels of allergen-specific immunoglobulin E and reduced release of mouse mast cell protease-1, indicating a dampened immune response.
This research points towards selenium supplementation as a potential method to modulate allergic reactions to whey. By lowering specific antibody responses and mast cell activity, selenium might help lessen the severity of allergies associated with cow's milk. Overall, our findings could open up new avenues for managing food allergies effectively.
After subjecting the mice to a whey challenge, we noted some interesting changes. Notably, the body temperature of mice on a medium selenium diet was significantly higher 60 minutes post-challenge, suggesting a less severe allergic reaction. We also observed decreased levels of allergen-specific immunoglobulin E and reduced release of mouse mast cell protease-1, indicating a dampened immune response.
This research points towards selenium supplementation as a potential method to modulate allergic reactions to whey. By lowering specific antibody responses and mast cell activity, selenium might help lessen the severity of allergies associated with cow's milk. Overall, our findings could open up new avenues for managing food allergies effectively.
Read More
9
Selenium compound reduces allergy symptoms
Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators.
Direct relevance to allergy treatment
We explored how a novel water-soluble selenium compound, known as SeTal, impacts atopic dermatitis (AD), a common allergic skin condition. In experiments, we applied 2,4-dinitrochlorobenzene (DNCB) to sensitized mice, creating a model for AD symptoms. By treating these mice with either SeTal or hydrocortisone, we aimed to measure the severity of skin lesions and related inflammation.
The results were compelling. SeTal, at concentrations of 1% and 2%, showed significant effectiveness in reducing the symptoms and inflammatory indicators of AD. In fact, the results were comparable to, and in some cases, even better than the results achieved with hydrocortisone, a traditional steroid treatment often used for such conditions.
This study suggests that SeTal could offer a promising alternative for treating atopic dermatitis, providing a new avenue for those seeking relief from this chronic and often bothersome allergy-related skin issue. With common steroid treatments posing potential side effects, our findings around SeTal support exploring safer, more effective options in the future.
The results were compelling. SeTal, at concentrations of 1% and 2%, showed significant effectiveness in reducing the symptoms and inflammatory indicators of AD. In fact, the results were comparable to, and in some cases, even better than the results achieved with hydrocortisone, a traditional steroid treatment often used for such conditions.
This study suggests that SeTal could offer a promising alternative for treating atopic dermatitis, providing a new avenue for those seeking relief from this chronic and often bothersome allergy-related skin issue. With common steroid treatments posing potential side effects, our findings around SeTal support exploring safer, more effective options in the future.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Effective breathing aid
This helps with colds, allergies, sinus infections, and bronchitis, allowing me to breathe without side effects. Introduced to acetylcysteine during a bout of bronchitis, I was able to breathe more easily with no adverse effects from usual medications. Now, I can easily handle fall allergies and sinus issues as well, without needing Sudafed or Claritin. I take 2 a day as the maximum dose. It's incredibly beneficial and crucial for my body.
Read More
9.5
Child's improvement
It’s very effective; my child’s nose allergy has improved considerably, and he no longer coughs. The benefits include fighting free radicals and anti-oxidation, despite the slightly unpleasant smell.
9.5
Relieves sinus pressure
Incredible for sinus pressure and allergies. I'm amazed I'm off Claritin this Spring. I take it every other day; the instant I feel sinus pressure, one dose works like a miracle.
10
Miracle product
It perfectly cleanses the body! The results are phenomenal as my liver normalised and the allergy vanished, along with improved skin condition. Truly a miracle!
9.5
Immunity boost
A great product from a reputable brand. I use it daily to boost my immune system, and it seems effective, as I rarely get sick or experience respiratory issues with allergies now.
