In this study, we investigated the potential of Saccharomyces cerevisiae UFMG A-905 in reducing asthma-like symptoms in a mouse model. The mice were sensitized and then treated daily with the probiotic before and during the allergic challenges.
Our findings revealed that this yeast strain significantly reduced airway hyperresponsiveness and inflammatory markers typically linked to asthma. We noticed decreased airway inflammation, mucus production, and levels of key inflammatory cytokines.
Overall, the results suggest that S. cerevisiae UFMG A-905 could help in preventing allergic asthma, but further research is needed to understand its full potential.
Read More
8
Selenium intake boosts lung function
The correlation between selenium intake and lung function in asthmatic people: a cross-sectional study.
This study explored how selenium intake relates to lung function in people with asthma. We analyzed data from 4,541 participants in a national survey using various statistical methods. Our findings showed a positive connection between higher selenium intake and better lung function, particularly in forced vital capacity and forced expiratory volume. We noted that to potentially enhance respiratory health, asthma patients could benefit from consuming between 137.65 mcg and 200 mcg of selenium daily, while also being cautious of any adverse effects.
Read More
8
Saccharomyces cerevisiae shows asthma prevention
Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice.
We explored the impact of Saccharomyces cerevisiae UFMG A-905 on asthma prevention by giving it to pregnant mice and their offspring. Three groups received the yeast at different times in their development, while two control groups received a saline solution. The results showed that the offspring from the treated groups had significantly less airway hyperresponsiveness and lower levels of asthma-related substances compared to control mice. Interestingly, the strongest benefits were noted when the yeast was administered during lactation. Overall, this suggests that this unique yeast strain could be a promising option for asthma management.
Read More
Most Useful Reviews
7.5
Great asthma relief
2 people found this helpful
Great! I wish I’d known about these sooner. I'm very impressed; my asthma has improved significantly, and as a bonus, my hangovers have greatly decreased as well. I'm extremely happy.
Read More
9
Boosts respiration
NAC is incredible for its effects on allergies, asthma, coughing, detoxification, and general respiratory health. This product promotes liver and lung function because NAC effectively raises glutathione levels, the body's principal antioxidant.
Read More
9
Cleared lungs
I have asthma, and NAC significantly helps clear my lungs. It's also wonderful for detoxification.
In this study, we investigated the potential of Saccharomyces cerevisiae UFMG A-905 in reducing asthma-like symptoms in a mouse model. The mice were sensitized and then treated daily with the probiotic before and during the allergic challenges.
Our findings revealed that this yeast strain significantly reduced airway hyperresponsiveness and inflammatory markers typically linked to asthma. We noticed decreased airway inflammation, mucus production, and levels of key inflammatory cytokines.
Overall, the results suggest that S. cerevisiae UFMG A-905 could help in preventing allergic asthma, but further research is needed to understand its full potential.
Read More
8
Saccharomyces cerevisiae shows asthma prevention
Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice.
We explored the impact of Saccharomyces cerevisiae UFMG A-905 on asthma prevention by giving it to pregnant mice and their offspring. Three groups received the yeast at different times in their development, while two control groups received a saline solution. The results showed that the offspring from the treated groups had significantly less airway hyperresponsiveness and lower levels of asthma-related substances compared to control mice. Interestingly, the strongest benefits were noted when the yeast was administered during lactation. Overall, this suggests that this unique yeast strain could be a promising option for asthma management.
Read More
8
Saccharomyces cerevisiae shows promise
Dose-Response Effect of Saccharomyces cerevisiae UFMG A-905 on the Prevention of Asthma in an Animal Model.
We examined whether saccharomyces cerevisiae UFMG A-905 could help prevent asthma in a mouse model. The study evaluated different doses and regimens, revealing that daily giving of higher doses significantly reduced bronchial hyperresponsiveness—a key asthma symptom.
However, while we noticed improvements in hyperresponsiveness, there wasn’t a significant decrease in airway and lung inflammation with either regimen. Collectively, these findings suggest potential benefits of specific doses of this probiotic, but more research is needed to fully understand its effectiveness against asthma.
Read More
8
Selenium intake boosts lung function
The correlation between selenium intake and lung function in asthmatic people: a cross-sectional study.
This study explored how selenium intake relates to lung function in people with asthma. We analyzed data from 4,541 participants in a national survey using various statistical methods. Our findings showed a positive connection between higher selenium intake and better lung function, particularly in forced vital capacity and forced expiratory volume. We noted that to potentially enhance respiratory health, asthma patients could benefit from consuming between 137.65 mcg and 200 mcg of selenium daily, while also being cautious of any adverse effects.
Read More
8
Prenatal selenium exposure and allergies
Prenatal exposure to selenium, mercury, and manganese during pregnancy and allergic diseases in early childhood: The Japan Environment and Children's study.
We aimed to understand how prenatal exposure to selenium, alongside mercury and manganese, affects the risk of allergic diseases in children up to three years old.
Using data from nearly 95,000 mother-infant pairs from the Japan Environment and Children's Study, we discovered that selenium might help lower the risk of atopic dermatitis, food allergies, allergic rhinitis, and other allergic conditions, particularly when mercury exposure is low.
This suggests that maintaining a healthy level of selenium during pregnancy may be beneficial for children's health regarding allergies.
Great! I wish I’d known about these sooner. I'm very impressed; my asthma has improved significantly, and as a bonus, my hangovers have greatly decreased as well. I'm extremely happy.
Read More
9
Boosts respiration
NAC is incredible for its effects on allergies, asthma, coughing, detoxification, and general respiratory health. This product promotes liver and lung function because NAC effectively raises glutathione levels, the body's principal antioxidant.
Read More
9
Cleared lungs
I have asthma, and NAC significantly helps clear my lungs. It's also wonderful for detoxification.
Read More
8
Eases breathing
Detoxifier, expectorant, thinning phlegm. I ordered NAC for detox, liver, and bronchial cleansing. I began taking it when diagnosed with bronchial asthma and suffering from a lingering cold for two months. It has become much easier; the phlegm started to drain and my coughing ceased. I intend to repeat this medication.
Read More
7
Mucus removal
18 people found this helpful
I recommend this product. I tested it on patients: it effectively removes mucus and aids with ARVI, preventing excess nasal congestion. My health is stable, and I am even working. It has good detoxification and anti-inflammatory effects. There are observations of improvements with bronchial asthma. I rated it four stars for now and will update if I notice more benefits. I hope my review is helpful; stay healthy and happy!
Asthma is a chronic condition that affects the airways in the lungs, resulting in symptoms like wheezing, coughing, shortness of breath, and chest tightness. The airways can become inflamed and narrowed, making it difficult to breathe, especially during physical activities or during an asthma attack triggered by allergens, irritants, or stress. While asthma can affect individuals of any age, it often begins in childhood, and its severity can vary from mild to life-threatening.
Management of asthma involves avoiding known triggers and using medications such as inhalers that contain bronchodilators and corticosteroids to reduce inflammation and improve airflow. Regular check-ups with a healthcare provider can help individuals manage their condition effectively and develop an asthma action plan tailored to their specific needs. With proper management, many individuals with asthma lead active, healthy lives.
N-Acetyl Cysteine (NAC) is a modified form of the amino acid cysteine, known for its role as a powerful antioxidant and mucolytic agent. It has been widely used as a dietary supplement for various health benefits, including supporting respiratory health, detoxification, and enhancing overall immune function. NAC is particularly recognized for its ability to replenish glutathione, one of the body's most important antioxidants, which helps combat oxidative stress and protect cells from damage.
In addition to its antioxidant properties, N-Acetyl Cysteine is commonly leveraged in a clinical setting for its effectiveness in treating acetaminophen (Tylenol) overdoses, as it aids in restoring depleted glutathione levels, thus preventing liver damage. It can also be beneficial for individuals with chronic respiratory conditions, such as COPD or cystic fibrosis, as it helps in thinning mucus, making it easier to expel. While NAC is generally considered safe for most people, it’s important to consult a healthcare professional before starting any new supplement, particularly for those with pre-existing conditions or those already on medication.
Research suggests that N-Acetyl Cysteine (NAC) may offer some benefits for individuals with asthma, primarily due to its role as a mucolytic agent. It works by thinning mucus in the airways, which can help to improve airflow and potentially alleviate symptoms during asthma attacks. Some studies indicate that NAC may reduce the frequency of exacerbations in those with asthma, particularly when combined with standard asthma medications. However, it’s essential to approach this supplement cautiously, as results can vary, and NAC is not a substitute for prescribed asthma treatments.
While NAC shows promise, it is not universally accepted as a first-line treatment for asthma. If you’re considering adding NAC to your asthma management plan, it's imperative to consult with a healthcare professional first. They can provide guidance based on your specific condition and any other medications you may be taking. Always approach new treatments with care and prioritize evidence-based therapies that are proven to be effective.
Based on user reviews, the timeline for seeing results when using NAC for asthma can vary widely among individuals. Some users report significant improvements shortly after they start taking the supplement. For example, one reviewer noted that their asthma improved significantly and that they were extremely happy with the results after beginning the use of NAC Read Review. Another user experienced noticeable easing of bronchial symptoms and reduced coughing within a short period after starting NAC Read Review.
Other reviewers hinted at a gradual improvement, suggesting that it might take some time to fully experience its benefits. One user mentioned being hopeful for ongoing improvements with their asthma symptoms, implying that while initial benefits were felt, they also anticipated more positive changes over time Read Review. Overall, many users indicate that noticeable benefits can begin within days to weeks, but the full effects may depend on various factors, including individual health and consistency of use.
The scientific research surrounding the use of Saccharomyces cerevisiae, particularly the UFMG A-905 strain, shows promising potential for asthma management, particularly in preclinical models. Studies have demonstrated that administering this yeast to pregnant mice and their offspring resulted in significantly less airway hyperresponsiveness and lower levels of asthma-related substances compared to control groups. Notably, stronger benefits were observed when the yeast was provided during lactation ([1]). Other research support this, indicating that probiotic bread made with UFMG A-905 can decrease airway inflammation and hyperresponsiveness in mice exposed to allergens, highlighting its innovative approach in asthma management ([2]).
While results are promising, they largely stem from animal studies, and more extensive clinical trials involving human subjects are necessary to confirm its effectiveness in asthma treatment. For instance, findings show that high doses of Saccharomyces cerevisiae resulted in reduced bronchial hyperresponsiveness, although the effect on inflammation was not significant ([3]). Thus, while existing animal studies are encouraging, further research is essential to determine the practical applicability of Saccharomyces cerevisiae in treating asthma effectively in humans.
Based on user reviews, many individuals have reported substantial improvements in their asthma symptoms after incorporating NAC into their routines. One user expressed extreme satisfaction, noting a significant reduction in asthma severity and even mentioning a decrease in hangovers as an added benefit Read Review. Similarly, another reviewer highlighted NAC's ability to clear their lungs effectively, emphasizing its role in enhancing detoxification processes Read Review. Users have also pointed to its effectiveness in thinning phlegm and alleviating coughing, which drastically improved their respiratory health Read Review.
Moreover, a reviewer who tested it on patients observed that NAC effectively removes mucus and improves bronchial conditions, showcasing its broad benefits for respiratory health Read Review. While many have experienced positive outcomes, some users, like one who remains hopeful for further improvements, acknowledge that individual results can vary. This underscores that while NAC may provide noticeable relief for some, others might still be in the early stages of experiencing its benefits Read Review. Overall, users emphasize that the benefits extend beyond just asthma relief, contributing to better overall respiratory and liver health.
Based on user reviews, there is a notable synergy reported by individuals combining NAC with other supplements for managing asthma. One user specifically mentioned their intention to combine NAC with glutathione as a cost-effective strategy to enhance their asthma management Read Review. Another reviewer highlighted that NAC not only aids in clearing lungs but also supports detoxification, suggesting its complementary effects, particularly for those with respiratory conditions Read Review.
Users generally report favorable outcomes when using NAC alongside other health-promoting supplements, underlining the importance of raising glutathione levels in the body to improve overall respiratory health and liver function Read Review. For instance, one user observed benefits in detoxification, bronchial cleansing, and reducing phlegm as a result of their NAC use, indicating that multiple supplements can work together for enhanced relief Read Review. Overall, users seem to find that combining NAC with other supplements can contribute to better asthma management and improved general health.
Based on user reviews, N-Acetyl Cysteine (NAC) appears to be helpful for managing asthma symptoms through various mechanisms such as detoxification and improving lung function. Users report that NAC significantly aids in clearing the lungs and reducing phlegm, leading to noticeable improvements in respiratory health. For instance, one user noted that after starting NAC, their coughing ceased, and they felt much better overall, particularly during a bout of bronchial asthma accompanied by a lingering cold Read Review. Another user mentioned substantial benefits, including a reduction in asthma attacks, attributing their improved condition to the effective maintenance of health provided by NAC Read Review.
While specific dosage information is not provided in the reviews, the general consensus highlights that users advocate for the use of NAC due to its efficacy in alleviating asthma symptoms alongside other health benefits, such as liver detoxification Read Review. Many users express a commitment to continue using NAC, which suggests they may have found a suitable dose through their own experiences, although recommendations vary and could depend on individual health needs. As such, those considering NAC for asthma management should consult with a healthcare professional for personalized dosing recommendations.
7.5
Great asthma relief
2 people found this helpful
Great! I wish I’d known about these sooner. I'm very impressed; my asthma has improved significantly, and as a bonus, my hangovers have greatly decreased as well. I'm extremely happy.
8
Eases breathing
Detoxifier, expectorant, thinning phlegm. I ordered NAC for detox, liver, and bronchial cleansing. I began taking it when diagnosed with bronchial asthma and suffering from a lingering cold for two months. It has become much easier; the phlegm started to drain and my coughing ceased. I intend to repeat this medication.
7.5
Reduced anxiety attacks
7 people found this helpful
I'm hopeful for improvements in my asthma. Although I initially struggled to find NAC, I managed to buy it thanks to my friend. I used to fret about having my suction machine nearby, but lately, I've not had any attacks. The ingredient N-acetylcysteine helps maintain health effectively, and I plan to combine it with glutathione, particularly as it's more cost-effective.
9
Cleared lungs
I have asthma, and NAC significantly helps clear my lungs. It's also wonderful for detoxification.
7
Mucus removal
18 people found this helpful
I recommend this product. I tested it on patients: it effectively removes mucus and aids with ARVI, preventing excess nasal congestion. My health is stable, and I am even working. It has good detoxification and anti-inflammatory effects. There are observations of improvements with bronchial asthma. I rated it four stars for now and will update if I notice more benefits. I hope my review is helpful; stay healthy and happy!
9
Boosts respiration
NAC is incredible for its effects on allergies, asthma, coughing, detoxification, and general respiratory health. This product promotes liver and lung function because NAC effectively raises glutathione levels, the body's principal antioxidant.
8
Saccharomyces cerevisiae shows asthma prevention
Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice.
We explored the impact of Saccharomyces cerevisiae UFMG A-905 on asthma prevention by giving it to pregnant mice and their offspring. Three groups received the yeast at different times in their development, while two control groups received a saline solution. The results showed that the offspring from the treated groups had significantly less airway hyperresponsiveness and lower levels of asthma-related substances compared to control mice. Interestingly, the strongest benefits were noted when the yeast was administered during lactation. Overall, this suggests that this unique yeast strain could be a promising option for asthma management.
7
UFMG A-905 yeast helps asthma
A Functional Bread Fermented with UFMG A-905 Prevents Allergic Asthma in Mice.
We investigated the potential of bread fermented with UFMG A-905 yeast to prevent asthma in mice. The study involved creating three types of breads, and mice were exposed to allergens after consuming them.
Results showed that the UFMG A-905 bread, especially when combined with microcapsules, not only increased yeast counts but also decreased airway inflammation and hyperresponsiveness.
These findings suggest that this innovative probiotic bread could offer a promising approach to asthma management.
8
Saccharomyces cerevisiae shows promise
Dose-Response Effect of Saccharomyces cerevisiae UFMG A-905 on the Prevention of Asthma in an Animal Model.
We examined whether saccharomyces cerevisiae UFMG A-905 could help prevent asthma in a mouse model. The study evaluated different doses and regimens, revealing that daily giving of higher doses significantly reduced bronchial hyperresponsiveness—a key asthma symptom.
However, while we noticed improvements in hyperresponsiveness, there wasn’t a significant decrease in airway and lung inflammation with either regimen. Collectively, these findings suggest potential benefits of specific doses of this probiotic, but more research is needed to fully understand its effectiveness against asthma.
References
Sandy CM, Guimarães CC, Fonseca VMB, Nicoli JR, Martins FS, et al. Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice. Benef Microbes. 2024;16:125. 10.1163/18762891-bja00044
Calazans APCT, Milani TMS, Prata AS, Clerici MTPS, Nicoli JR, et al. A Functional Bread Fermented with UFMG A-905 Prevents Allergic Asthma in Mice. Curr Dev Nutr. 2024;8:102142. 10.1016/j.cdnut.2024.102142
Milani TMS, Sandy CM, Calazans APCT, Silva RQ, Fonseca VMB, et al. Dose-Response Effect of Saccharomyces cerevisiae UFMG A-905 on the Prevention of Asthma in an Animal Model. Probiotics Antimicrob Proteins. 2024;16:53. 10.1007/s12602-022-10014-w
Fonseca VMB, Milani TMS, Prado R, Bonato VLD, Ramos SG, et al. Oral administration of Saccharomyces cerevisiae UFMG A-905 prevents allergic asthma in mice. Respirology. 2017;22:905. 10.1111/resp.12990
da Silva-Martins CL, Couto SC, Muniz-Junqueira MI. Inhaled corticosteroid treatment for 6 months was not sufficient to normalize phagocytosis in asthmatic children. Clin Transl Allergy. 2013;3:28. 10.1186/2045-7022-3-28
Sarinho E, Medeiros D, Schor D, Rego Silva A, Sales V, et al. Production of interleukin-10 in asthmatic children after Beta-1-3-glucan. Allergol Immunopathol (Madr). 2009;37:188. 10.1016/j.aller.2009.02.005
Ahoon M, Farid-Hosseini R, Tehrani H, Rafat-Panah H, Ahanchian H, et al. Evaluation the Effect of Supplements Containing Vitamin D and Trace Elements in Patients with Moderate to Severe Asthma. Rep Biochem Mol Biol. 2024;13:40. 10.61186/rbmb.13.1.40
Jiang H, Yang G, Chen J, Yuan S, Wu J, et al. The correlation between selenium intake and lung function in asthmatic people: a cross-sectional study. Front Nutr. 2024;11:1362119. 10.3389/fnut.2024.1362119
Miyazaki J, Ikehara S, Tanigawa K, Kimura T, Ueda K, et al. Prenatal exposure to selenium, mercury, and manganese during pregnancy and allergic diseases in early childhood: The Japan Environment and Children's study. Environ Int. 2023;179:108123. 10.1016/j.envint.2023.108123
Kuti BP, Kuti DK, Smith OS. Serum Zinc, Selenium and Total Antioxidant Contents of Nigerian Children with Asthma: Association with Disease Severity and Symptoms Control. J Trop Pediatr. 2020;66:395. 10.1093/tropej/fmz078
Smits JE, Krohn RM, Akhtar E, Hore SK, Yunus M, et al. Food as medicine: Selenium enriched lentils offer relief against chronic arsenic poisoning in Bangladesh. Environ Res. 2019;176:108561. 10.1016/j.envres.2019.108561
Baïz N, Chastang J, Ibanez G, Annesi-Maesano I. Prenatal exposure to selenium may protect against wheezing in children by the age of 3. Immun Inflamm Dis. 2017;5:37. 10.1002/iid3.138
Tenero L, Piazza M, Zanoni L, Bodini A, Peroni D, et al. Antioxidant supplementation and exhaled nitric oxide in children with asthma. Allergy Asthma Proc. 2016;37:e8. 10.2500/aap.2016.37.3920
Min-Chang G, Wei-Hong T, Zhen X, Jie S. Effects of Selenium-Enriched Protein from Ganoderma lucidum on the Levels of IL-1 β and TNF- α , Oxidative Stress, and NF- κ B Activation in Ovalbumin-Induced Asthmatic Mice. Evid Based Complement Alternat Med. 2014;2014:182817. 10.1155/2014/182817