Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.8
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg

Top Medical Research Studies

8
Selenium shows promise for migraines
We explored the effects of selenium supplementation in a double-blinded trial involving 72 patients with migraines. Over 12 weeks, participants received either selenium or a placebo. We observed that those taking selenium experienced reduced headache frequency and severity.

Additionally, selenium improved antioxidant levels and lowered oxidative stress markers. However, it appears that many other factors related to migraine symptoms did not see significant changes. While this research shows promise, further studies are necessary to confirm these findings.
Read More
7
Higher selenium may reduce migraines
We examined how dietary selenium affects the occurrence of migraines, especially looking at age differences. Analyzing data from nearly 10,000 adults in the NHANES survey, we found that higher selenium intake is linked to fewer migraines.

This beneficial effect seems particularly significant for adults aged 20 to 50, where increasing selenium to about 101.9 µg/day appears to help prevent migraines. However, the relationship is complex and influenced by age, highlighting the importance of adequate selenium-rich foods for this age group.
Read More
7
Sodium selenite shows symptom improvement
We explored how sodium selenite affects symptoms in patients with brain tumors. This study included 32 patients who experienced increased intracranial pressure after previous treatments.

Notably, 76% of participants reported significant improvements in their symptoms, including headaches, while 24% experienced slight improvements.

Treatments also positively impacted blood cell counts and enhanced the effects of oxygen therapy. Overall, sodium selenite could be a promising part of supportive care for brain tumor patients experiencing multiple symptoms.
Read More

Most Useful Reviews

9
Headaches gone
37 people found this helpful
I advised my family to take this for the cold season to boost immunity. My mother praises this supplement, stating her headaches have disappeared, and her arterial pressure has normalised. It’s wonderful to see her cheerful and baking pies again!
Read More
10
Cardio without discomfort
4 people found this helpful
I absolutely love this product! I can perform cardio without suffering from headaches now that I’m taking this supplement. Since starting NAC, I’ve not experienced a headache, which I previously dealt with due to side effects from the HPV vaccine.
Read More
9
Headaches gone
I've been taking NAC with selenium for a month, noticing significant improvements! My energy has surged, overall wellbeing has enhanced, constant headaches disappeared, and my skin has cleared up. I appreciate how this supplement helps the body fight toxins. I recommend it for anyone wanting to safeguard their health!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
  • All Researches
8
Selenium shows promise for migraines
We explored the effects of selenium supplementation in a double-blinded trial involving 72 patients with migraines. Over 12 weeks, participants received either selenium or a placebo. We observed that those taking selenium experienced reduced headache frequency and severity.

Additionally, selenium improved antioxidant levels and lowered oxidative stress markers. However, it appears that many other factors related to migraine symptoms did not see significant changes. While this research shows promise, further studies are necessary to confirm these findings.
Read More
7
Higher selenium may reduce migraines
We examined how dietary selenium affects the occurrence of migraines, especially looking at age differences. Analyzing data from nearly 10,000 adults in the NHANES survey, we found that higher selenium intake is linked to fewer migraines.

This beneficial effect seems particularly significant for adults aged 20 to 50, where increasing selenium to about 101.9 µg/day appears to help prevent migraines. However, the relationship is complex and influenced by age, highlighting the importance of adequate selenium-rich foods for this age group.
Read More
7
Sodium selenite shows symptom improvement
We explored how sodium selenite affects symptoms in patients with brain tumors. This study included 32 patients who experienced increased intracranial pressure after previous treatments.

Notably, 76% of participants reported significant improvements in their symptoms, including headaches, while 24% experienced slight improvements.

Treatments also positively impacted blood cell counts and enhanced the effects of oxygen therapy. Overall, sodium selenite could be a promising part of supportive care for brain tumor patients experiencing multiple symptoms.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 16 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Headaches gone
37 people found this helpful
I advised my family to take this for the cold season to boost immunity. My mother praises this supplement, stating her headaches have disappeared, and her arterial pressure has normalised. It’s wonderful to see her cheerful and baking pies again!
Read More
10
Cardio without discomfort
4 people found this helpful
I absolutely love this product! I can perform cardio without suffering from headaches now that I’m taking this supplement. Since starting NAC, I’ve not experienced a headache, which I previously dealt with due to side effects from the HPV vaccine.
Read More
9
Headaches gone
I've been taking NAC with selenium for a month, noticing significant improvements! My energy has surged, overall wellbeing has enhanced, constant headaches disappeared, and my skin has cleared up. I appreciate how this supplement helps the body fight toxins. I recommend it for anyone wanting to safeguard their health!
Read More
7
Sinus headache help
125 people found this helpful
This helped to cure my sinus problems by 80-90%. NAC is a key ingredient in many natural sinus treatments, alleviating sinus headaches, runny nose, and watery eyes. I take 2000mg daily during allergy episodes, which has greatly improved my symptoms.
Read More
7.5
Helps with headaches
2 people found this helpful
An essential supplement for boosting my glutathione levels. It aids in managing intoxication and headaches during illness.
Read More

Frequently Asked Questions

10
Cardio without discomfort
4 people found this helpful
I absolutely love this product! I can perform cardio without suffering from headaches now that I’m taking this supplement. Since starting NAC, I’ve not experienced a headache, which I previously dealt with due to side effects from the HPV vaccine.
9
Headaches gone
I've been taking NAC with selenium for a month, noticing significant improvements! My energy has surged, overall wellbeing has enhanced, constant headaches disappeared, and my skin has cleared up. I appreciate how this supplement helps the body fight toxins. I recommend it for anyone wanting to safeguard their health!
2
Not effective for me
I may be an outlier, but I experienced a terrible headache after taking this. It might be a side effect of detox, but it didn’t seem effective for me. Doctor's Best is a reputable brand that I trust, so I don't believe it’s the brand itself. It might simply not suit me, perhaps it works too well, or I could be too sensitive to it.
2
Headaches from dosage
1 people found this helpful
I work in a hospital, so I purchased this for detoxification from vaccine shedding. Although I was meant to take two pills daily, I experienced headaches. Upon researching, I discovered that glutathione can cause headaches occasionally. I paused for a while but resumed with one pill daily, which relieved my headaches. The capsule size is manageable, and I didn’t notice any unpleasant smell, so I recommend it for those concerned about shedding.
6
Assists with headaches
2 people found this helpful
Besides NAC, it includes selenium and molybdenum. It alleviates headaches when detoxification phases falter. I would take NAC and magnesium anywhere.
1
Caused severe headaches
A lot of positive reviews prompted me to buy this for my husband for prevention, but it did not suit him. After a week of use, it caused severe headaches, and we tried it several times.
7.5
Excellent for headaches
Fantastic! A quick remedy for colds and headaches. NAC acts as a precursor to glutathione and plays a role in detoxification.
7
Higher selenium may reduce migraines
We examined how dietary selenium affects the occurrence of migraines, especially looking at age differences. Analyzing data from nearly 10,000 adults in the NHANES survey, we found that higher selenium intake is linked to fewer migraines.

This beneficial effect seems particularly significant for adults aged 20 to 50, where increasing selenium to about 101.9 µg/day appears to help prevent migraines. However, the relationship is complex and influenced by age, highlighting the importance of adequate selenium-rich foods for this age group.
8
Selenium shows promise for migraines
We explored the effects of selenium supplementation in a double-blinded trial involving 72 patients with migraines. Over 12 weeks, participants received either selenium or a placebo. We observed that those taking selenium experienced reduced headache frequency and severity.

Additionally, selenium improved antioxidant levels and lowered oxidative stress markers. However, it appears that many other factors related to migraine symptoms did not see significant changes. While this research shows promise, further studies are necessary to confirm these findings.
7
Sodium selenite shows symptom improvement
We explored how sodium selenite affects symptoms in patients with brain tumors. This study included 32 patients who experienced increased intracranial pressure after previous treatments.

Notably, 76% of participants reported significant improvements in their symptoms, including headaches, while 24% experienced slight improvements.

Treatments also positively impacted blood cell counts and enhanced the effects of oxygen therapy. Overall, sodium selenite could be a promising part of supportive care for brain tumor patients experiencing multiple symptoms.

References

  1. Yu X, Wu L, Zheng H, Wu W, Tian S. Interaction between dietary selenium intake and age on severe headache or migraine in the United States: a population-based study. Front Nutr. 2025;12:1537151. 10.3389/fnut.2025.1537151
  2. Balali A, Sadeghi O, Khorvash F, Rouhani MH, Askari G. The effect of selenium supplementation on oxidative stress, clinical and physiological symptoms in patients with migraine: a double-blinded randomized clinical trial. Front Nutr. 2024;11:1369373. 10.3389/fnut.2024.1369373
  3. Pakdaman A. Symptomatic treatment of brain tumor patients with sodium selenite, oxygen, and other supportive measures. Biol Trace Elem Res. 1998;62:1.
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