Last update
4/9/2026
Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.5
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg
📅 Last updated:

Top Medical Research Studies

7
Selenium boosts antioxidant status
We sought to understand how a mineral-vitamin complex, specifically Selzinc-plus, may help treat chronic abacterial prostatitis, a condition often linked with pelvic pain. In a study involving 47 men, we divided them into two groups: one received standard therapy, and the other received additional Selzinc-plus for two months.

While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.
Read More
We focused on the effects of a dietary supplement combining several natural ingredients, including selenium, on chronic pelvic pain in men with Category IIIA prostatitis.

Patients taking this supplement showed significant reductions in inflammation and pain, as evidenced by lower white blood cell counts in seminal fluid and improved pain scores.

These findings suggest that selenium, along with other nutrients, may play a beneficial role in alleviating pelvic pain associated with chronic prostatitis.
Read More
8
Selenium enhances pelvic pain treatment
We evaluated the effects of a treatment combining Serenoa repens with selenium and lycopene, known as Profluss, against Serenoa repens alone for chronic pelvic pain in 102 men. After an 8-week period, both groups experienced symptom improvements. However, the Profluss group showed a significantly greater reduction in pelvic pain scores and additional benefits in other measures, suggesting that selenium can enhance treatment effectiveness for this condition.

While both treatments offered relief, Profluss was particularly beneficial. This finding indicates that adding selenium to standard therapy might be advantageous in managing pelvic pain.
Read More

Most Useful Reviews

9
Bronchitis relief
Cleans the bronchi effectively. My chronic bronchitis has gradually receded while taking NAC. The chest pain is fading, and I no longer have a cough. I am beginning to return to my normal life. This has been a godsend for me.
Read More
7.5
Eased chronic pain
4 people found this helpful
I began drinking this daily as a preventive measure against Covid. Suffering from chronic nasopharyngitis, I found that taking this could relieve the pain and allowed me to expectorate sputum easily. It's been effective, and I feel less pain, making my daily activities more manageable.
Read More
9
Pain relief noted
1 people found this helpful
It works for some reason. It all started with a gift from my family. There have been several occasions when I took NAC while experiencing pain due to rheumatism, and the pain was surprisingly alleviated the following morning. This has occurred multiple times, leading me to believe it has a positive effect on my body. I take it each time I am in crowded places. As I experience stomach ache when taking capsules, I break them open and consume only the powder inside.
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
  • All Researches
8
Multimodal therapy improves pelvic pain
We examined the potential of a multimodal therapy approach for treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using the UPOINTS phenotyping system. Involving 914 patients, the study combined α-blockers, supplements like selenium, and antibacterial agents among others.

After a six-month course, we noted significant improvements in symptoms, with 77.5% of patients achieving a meaningful reduction in their pain scores. Notably, patients with the inflammatory subtype showed marked symptom relief compared to the non-inflammatory group. This suggests a tailored approach could effectively address the complexities of CP/CPPS.
Read More
8
Selenium enhances pelvic pain treatment
We evaluated the effects of a treatment combining Serenoa repens with selenium and lycopene, known as Profluss, against Serenoa repens alone for chronic pelvic pain in 102 men. After an 8-week period, both groups experienced symptom improvements. However, the Profluss group showed a significantly greater reduction in pelvic pain scores and additional benefits in other measures, suggesting that selenium can enhance treatment effectiveness for this condition.

While both treatments offered relief, Profluss was particularly beneficial. This finding indicates that adding selenium to standard therapy might be advantageous in managing pelvic pain.
Read More
7
Selenium boosts antioxidant status
We sought to understand how a mineral-vitamin complex, specifically Selzinc-plus, may help treat chronic abacterial prostatitis, a condition often linked with pelvic pain. In a study involving 47 men, we divided them into two groups: one received standard therapy, and the other received additional Selzinc-plus for two months.

While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.
Read More
We focused on the effects of a dietary supplement combining several natural ingredients, including selenium, on chronic pelvic pain in men with Category IIIA prostatitis.

Patients taking this supplement showed significant reductions in inflammation and pain, as evidenced by lower white blood cell counts in seminal fluid and improved pain scores.

These findings suggest that selenium, along with other nutrients, may play a beneficial role in alleviating pelvic pain associated with chronic prostatitis.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 11 Reviews
7.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Bronchitis relief
Cleans the bronchi effectively. My chronic bronchitis has gradually receded while taking NAC. The chest pain is fading, and I no longer have a cough. I am beginning to return to my normal life. This has been a godsend for me.
Read More
7.5
Eased chronic pain
4 people found this helpful
I began drinking this daily as a preventive measure against Covid. Suffering from chronic nasopharyngitis, I found that taking this could relieve the pain and allowed me to expectorate sputum easily. It's been effective, and I feel less pain, making my daily activities more manageable.
Read More
9
Pain relief noted
1 people found this helpful
It works for some reason. It all started with a gift from my family. There have been several occasions when I took NAC while experiencing pain due to rheumatism, and the pain was surprisingly alleviated the following morning. This has occurred multiple times, leading me to believe it has a positive effect on my body. I take it each time I am in crowded places. As I experience stomach ache when taking capsules, I break them open and consume only the powder inside.
Read More
7.5
Inflammation decrease
This NAC product is excellent. I have considerable inflammation in my body, and I noticed it reduces inflammation and consequently pain. Additionally, I observed that I am not as congested and wheezing as before.
Read More
2
Improved health issues
8 people found this helpful
Beware of long-term use. While this NAC may be a good quality product, it doesn't suit everyone, particularly those with high inflammation or histamine issues. After two years of daily use, I experienced worsened sleep, elevated blood pressure, and knee pain. Upon discovering that NAC inhibits methylation—an essential biochemical process—I substituted it with a methyl donor, TMG, leading to improvements in my symptoms. It's crucial to be cautious about the duration of NAC consumption, as advice and positive experiences from others may not apply universally.
Read More

Frequently Asked Questions

7.5
Reduced menstrual pain
2 people found this helpful
I've found that this supplement seems beneficial for alleviating menstrual pain and improving overall comfort during my cycles. It has positively influenced my long-term well-being regarding pelvic pain.
9
Bronchitis relief
Cleans the bronchi effectively. My chronic bronchitis has gradually receded while taking NAC. The chest pain is fading, and I no longer have a cough. I am beginning to return to my normal life. This has been a godsend for me.
7
Joint pain relief
Super remedy. I felt almost immediate relief from my joint issues, characterised by increased uric acid. Almost instantly, the redness diminished, and the pain in my joints lessened.
7.5
Bone pain reduction
1 people found this helpful
Effective. I take NAC from a different brand, which was out of stock, but it contains the same ingredients in higher doses. Thanks to that and glutathione, my skin is soft, beautiful, and my hair is magnificent. I feel great, and my mother takes it as well, reporting less bone pain. I highly recommend taking NAC and glutathione; it may be costly, but it is genuinely effective.
2
Improved health issues
8 people found this helpful
Beware of long-term use. While this NAC may be a good quality product, it doesn't suit everyone, particularly those with high inflammation or histamine issues. After two years of daily use, I experienced worsened sleep, elevated blood pressure, and knee pain. Upon discovering that NAC inhibits methylation—an essential biochemical process—I substituted it with a methyl donor, TMG, leading to improvements in my symptoms. It's crucial to be cautious about the duration of NAC consumption, as advice and positive experiences from others may not apply universally.
7
Selenium boosts antioxidant status
We sought to understand how a mineral-vitamin complex, specifically Selzinc-plus, may help treat chronic abacterial prostatitis, a condition often linked with pelvic pain. In a study involving 47 men, we divided them into two groups: one received standard therapy, and the other received additional Selzinc-plus for two months.

While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.
8
Multimodal therapy improves pelvic pain
We examined the potential of a multimodal therapy approach for treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using the UPOINTS phenotyping system. Involving 914 patients, the study combined α-blockers, supplements like selenium, and antibacterial agents among others.

After a six-month course, we noted significant improvements in symptoms, with 77.5% of patients achieving a meaningful reduction in their pain scores. Notably, patients with the inflammatory subtype showed marked symptom relief compared to the non-inflammatory group. This suggests a tailored approach could effectively address the complexities of CP/CPPS.
We focused on the effects of a dietary supplement combining several natural ingredients, including selenium, on chronic pelvic pain in men with Category IIIA prostatitis.

Patients taking this supplement showed significant reductions in inflammation and pain, as evidenced by lower white blood cell counts in seminal fluid and improved pain scores.

These findings suggest that selenium, along with other nutrients, may play a beneficial role in alleviating pelvic pain associated with chronic prostatitis.
8
Selenium enhances pelvic pain treatment
We evaluated the effects of a treatment combining Serenoa repens with selenium and lycopene, known as Profluss, against Serenoa repens alone for chronic pelvic pain in 102 men. After an 8-week period, both groups experienced symptom improvements. However, the Profluss group showed a significantly greater reduction in pelvic pain scores and additional benefits in other measures, suggesting that selenium can enhance treatment effectiveness for this condition.

While both treatments offered relief, Profluss was particularly beneficial. This finding indicates that adding selenium to standard therapy might be advantageous in managing pelvic pain.

References

  1. Shevchenko S Y, Kulchavenya E V, Baranchukova A A. [The possibility of correcting oxidative stress in patients with inflammatory type of chronic abacterial prostatitis (chronic pelvic pain syndrome category IIIa)]. Urologiia. 2023. PubMed
  2. Magri V, Marras E, Restelli A, Wagenlehner FM, Perletti G. Multimodal therapy for category III chronic prostatitis/chronic pelvic pain syndrome in UPOINTS phenotyped patients. Exp Ther Med. 2015;9:658. PubMed
  3. Lombardo F, Fiducia M, Lunghi R, Marchetti L, Palumbo A, et al. Effects of a dietary supplement on chronic pelvic pain syndrome (Category IIIA), leucocytospermia and semen parameters. Andrologia. 2012;44 Suppl 1:672. 10.1111/j.1439-0272.2011.01248.x
  4. Morgia G, Mucciardi G, Galì A, Madonia M, Marchese F, et al. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study. Urol Int. 2010;84:400. 10.1159/000302716
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