We explored the connection between vitamin D levels and upper respiratory tract infections (URTIs) among military recruits during their training. This observation spanned across different seasons and included over 1,600 recruits. Our aim was to understand how achieving sufficient vitamin D levels could potentially impact the frequency and severity of colds among physically active individuals.
In an additional phase of the research, we conducted a randomized controlled trial with 250 male recruits. They received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplements during winter. This comparison allowed us to see if these methods effectively increased vitamin D levels to a sufficient status of 25(OH)D at 50 nmol/L or higher.
Notably, our findings showed that only 21% of recruits had adequate vitamin D during winter, yet those who did were 40% less likely to suffer from URTIs. Furthermore, both vitamin D supplementation strategies similarly helped nearly all participants achieve sufficient levels. Vitamin D supplementation notably reduced the severity of URTI symptoms by 15% and the number of days with URTIs by 36% compared to placebo.
While the supplementation strategies did not significantly alter other immune factors, such as salivary secretory immunoglobulin A, the overall reduction in respiratory infections indicates a beneficial effect of maintaining vitamin D sufficiency during military training.
Read More
8
Vitamin D3 aids cold recovery
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored how 25-hydroxyvitamin D3 (25OHD), a form of vitamin D, influences upper respiratory tract infections (URTIs), commonly known as colds. In a carefully designed clinical study, we followed 428 participants aged 45 to 74 over a 16-week period. They were randomly assigned to receive either 10 μg of 25OHD daily or a placebo, all while maintaining a double-blind setup to ensure accurate results.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
Read More
7
Vitamin D's limited cold impact
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 months: a systematic review and meta-analysis.
We evaluated the impact of high-dose vitamin D supplementation, specifically doses exceeding the standard 400 IU, on preventing colds and other infections in children under five years of age. Our analysis included seven studies, involving a total of 5,748 children, which looked into how effective vitamin D might be in reducing the incidence of upper respiratory tract infections.
Interestingly, while our findings showed no significant benefit of high-dose vitamin D on the prevention of upper respiratory tract infections as a whole, we did observe a noteworthy reduction in specific illness occurrences. We noted a 57% reduction in colds, a 56% reduction in coughs, and a 59% decrease in fever rates with daily doses exceeding 1,000 IU.
However, we must approach these findings with caution, as the evidence supporting the reduction in cough and fever was of lower certainty. No significant effects were observed regarding other conditions such as bronchitis or otitis media. Overall, while high-dose vitamin D may help with colds specifically, further research is needed to solidify these conclusions.
Read More
Most Useful Reviews
9
Eases cold symptoms
1 people found this helpful
Best vitamin D ever! Initially, I thought it was dearer than others, but after experiencing relief from a cold and sore throat by taking 2 pills of 10,000, I purchased a second bottle. The symptoms vanished by evening!
Read More
9
Effective against colds
I periodically order this vitamin; it helps during colds. The result is 💯, the taste is pleasant, and it does not irritate my stomach.
Read More
9
Essential supplement
Vit D3 is my go-to supplement to combat colds and flu. The 10,000iu dosage is essential for me in northern climates.
We explored the connection between vitamin D levels and upper respiratory tract infections (URTIs) among military recruits during their training. This observation spanned across different seasons and included over 1,600 recruits. Our aim was to understand how achieving sufficient vitamin D levels could potentially impact the frequency and severity of colds among physically active individuals.
In an additional phase of the research, we conducted a randomized controlled trial with 250 male recruits. They received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplements during winter. This comparison allowed us to see if these methods effectively increased vitamin D levels to a sufficient status of 25(OH)D at 50 nmol/L or higher.
Notably, our findings showed that only 21% of recruits had adequate vitamin D during winter, yet those who did were 40% less likely to suffer from URTIs. Furthermore, both vitamin D supplementation strategies similarly helped nearly all participants achieve sufficient levels. Vitamin D supplementation notably reduced the severity of URTI symptoms by 15% and the number of days with URTIs by 36% compared to placebo.
While the supplementation strategies did not significantly alter other immune factors, such as salivary secretory immunoglobulin A, the overall reduction in respiratory infections indicates a beneficial effect of maintaining vitamin D sufficiency during military training.
Read More
8
Vitamin D3 aids cold recovery
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored how 25-hydroxyvitamin D3 (25OHD), a form of vitamin D, influences upper respiratory tract infections (URTIs), commonly known as colds. In a carefully designed clinical study, we followed 428 participants aged 45 to 74 over a 16-week period. They were randomly assigned to receive either 10 μg of 25OHD daily or a placebo, all while maintaining a double-blind setup to ensure accurate results.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
Read More
7
Vitamin D's limited cold impact
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 months: a systematic review and meta-analysis.
We evaluated the impact of high-dose vitamin D supplementation, specifically doses exceeding the standard 400 IU, on preventing colds and other infections in children under five years of age. Our analysis included seven studies, involving a total of 5,748 children, which looked into how effective vitamin D might be in reducing the incidence of upper respiratory tract infections.
Interestingly, while our findings showed no significant benefit of high-dose vitamin D on the prevention of upper respiratory tract infections as a whole, we did observe a noteworthy reduction in specific illness occurrences. We noted a 57% reduction in colds, a 56% reduction in coughs, and a 59% decrease in fever rates with daily doses exceeding 1,000 IU.
However, we must approach these findings with caution, as the evidence supporting the reduction in cough and fever was of lower certainty. No significant effects were observed regarding other conditions such as bronchitis or otitis media. Overall, while high-dose vitamin D may help with colds specifically, further research is needed to solidify these conclusions.
Read More
7
Vitamin D's role in Raynaud management
Serum vitamin B12 and D levels in children with Primary Raynaud Phenomenon: a retrospective cohort study.
We explored the impact of vitamin D and B12 deficiencies in children experiencing primary Raynaud phenomenon (RP), which causes temporary blood flow changes often triggered by cold or stress. Our study aimed to identify how common these vitamin deficiencies are in pediatric patients and whether they influenced the severity of Raynaud symptoms.
Out of 40 young participants, a significant portion—41.5% for vitamin B12 and 39% for vitamin D—showed low serum levels of these vitamins. After providing supplementation, we observed improved symptoms in many cases, particularly through warming techniques. However, it's important to note that while vasodilator treatment needs were generally unchanged regardless of vitamin B12 levels, those who had vitamin D deficiencies and subsequently received vitamin D treatment required significantly less vasodilator therapy.
Overall, while some positive effects of vitamin D were noted, further research is necessary to conclusively determine its role in managing primary RP symptoms and its effectiveness in combating cold-induced episodes.
Read More
7
Vitamin D reduces cold symptoms
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored the effects of 25-hydroxyvitamin D (25OHD) on individuals experiencing upper respiratory tract infections (URTIs), commonly known as colds. In a well-structured study, participants with low vitamin D levels received either a daily dose of 10 micrograms of 25OHD or a placebo for a span of 16 weeks. The participants' symptoms were assessed using the Wisconsin Upper Respiratory Symptom Survey-21, focusing on how the vitamin impacted their cold symptoms.
Our findings showed that those taking 25OHD reported significant reductions in physical symptoms such as runny noses, sneezing, and head congestion compared to those on the placebo. Additionally, the quality of life scores improved for most symptoms, except for ease of breathing. However, it’s important to note that there was no significant difference in the total number of cold events or how often participants used medications like antibiotics or pain relievers.
Collectively, these results suggest that adequate intake of vitamin D can help ease cold symptoms, particularly those affecting the nose, and might enhance overall well-being when a cold strikes. This indicates that vitamin D may play a positive role in managing the discomfort associated with upper respiratory infections.
Best vitamin D ever! Initially, I thought it was dearer than others, but after experiencing relief from a cold and sore throat by taking 2 pills of 10,000, I purchased a second bottle. The symptoms vanished by evening!
Read More
9
Effective against colds
I periodically order this vitamin; it helps during colds. The result is 💯, the taste is pleasant, and it does not irritate my stomach.
Read More
9
Essential supplement
Vit D3 is my go-to supplement to combat colds and flu. The 10,000iu dosage is essential for me in northern climates.
Read More
9
Rapid symptom relief
So far, so good! I initially tried this product and found it more expensive than others. However, I purchased a second bottle because I noticed that when I felt a cold and sore throat coming on, taking 2 pills of 10,000 iu in the late morning helped alleviate symptoms by evening.
Read More
9
Boosts immune system
2 people found this helpful
A good product! I used this to enhance my immune system, and remarkably, I haven't experienced any cold or flu symptoms this season.
Cold is a term that refers to a state of low temperature, often associated with a perceptibly chilly environment or the sensation of being cool to the touch. Scientifically, cold is relative to the presence and movement of heat, which is a measure of energy within matter. In everyday terms, we experience cold through weather changes, such as during winter months, and it can also be described in the context of specific temperature ranges – for example, temperatures below 32 degrees Fahrenheit (0 degrees Celsius) generally signify freezing conditions, which can impact outdoor activities, personal comfort, and various ecological systems.
Moreover, the sensation of cold is not solely dependent on temperature; factors like humidity and wind chill can enhance the feeling of coldness. When discussing cold in terms of human health, prolonged exposure to cold conditions can lead to hypothermia or frostbite if body heat is not effectively maintained. Hence, it's crucial to dress appropriately and take necessary precautions during colder months to prevent adverse effects. Understanding the concept of cold can help individuals better prepare for seasonal changes and ensure their comfort and safety.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
Vitamin D is often discussed in relation to immune health, and some studies suggest that it may play a role in reducing the risk of upper respiratory infections, including the common cold. Adequate levels of vitamin D might help enhance your immune response, potentially making your body more effective at fighting off infections. However, the evidence is not entirely conclusive, and while some individuals with low vitamin D levels may experience more frequent colds, it's important to consider that other factors also contribute to overall immunity, such as lifestyle and diet.
If you’re considering using vitamin D supplements to prevent or mitigate the effects of a cold, it’s always best to consult with a healthcare professional. They can provide tailored advice based on your specific health needs and possible deficiencies. While maintaining sufficient vitamin D levels can be beneficial for your immune system, it should not be seen as a guaranteed solution to avoid catching colds, especially during peak cold and flu seasons.
Based on user reviews, the timeline for seeing results from taking this supplement during a cold can vary, but many users report noticeable effects within a relatively short timeframe. For instance, one user indicated that they felt alleviation of symptoms within hours after taking a higher dose during the onset of a cold, stating that they noticed improvements by the evening of the same day (Read Review). Another user mentioned their cold lasted less than 28 hours, attributing this brevity to the supplement's positive impact on their immune system (Read Review).
Overall, users seem to agree that the supplement can provide quick relief from cold symptoms, particularly if taken at the first signs of illness. Many have experienced improved immune response and reduced cold duration, suggesting it is an effective option for bolstering health during cold season.
Vitamin D supplementation has shown some promise in alleviating symptoms associated with colds, though findings vary. Research indicates that individuals with sufficient vitamin D levels are less likely to suffer from upper respiratory tract infections (URTIs). In a study involving military recruits, those with adequate vitamin D were found to be 40% less likely to experience URTIs compared to their vitamin D deficient counterparts. Additionally, when participants were supplemented with vitamin D3, they reported a 15% reduction in the severity of cold symptoms and a 36% decrease in the number of days affected by URTIs [4].
However, the efficacy of vitamin D in preventing colds outright remains ambiguous, as some studies suggest minimal benefits in terms of reducing the incidence of respiratory infections, with findings indicating a notable reduction in cold occurrences when high doses of vitamin D exceeding 1,000 IU were administered [2]. Furthermore, while a variety of studies suggest that vitamin D can improve specific symptoms like runny noses and congestion, there’s limited consensus on its ability to prevent colds entirely. Overall, while incorporating vitamin D into one’s routine could potentially aid in managing cold symptoms and support overall well-being, more research is warranted to fully understand its effectiveness [6].
Users have reported a variety of positive experiences when taking this vitamin D3 supplement, especially during cold episodes. Many individuals highlight the supplement's immune-boosting properties, with one user noting that they have not experienced any cold or flu symptoms this season after incorporating it into their routine (Read Review). Another mentioned significant benefits in immune response during cold episodes, suggesting their symptoms felt lighter and more manageable (Read Review).
Additionally, multiple users emphasize quick relief from symptoms. For instance, one individual reported feeling better just hours after taking a higher dose at the onset of their symptoms (Read Review). The supplement's convenience and pleasant taste have also been appreciated, leading to a consistent repurchase among users, thanks to its overall effectiveness and ability to combat feelings of fatigue and enhance mood (Read Review). As always, it's essential to note that individual results may vary.
Users have reported that combining this vitamin D3 supplement with other immune support products can enhance its effectiveness in managing cold symptoms. One user emphasized that their higher dosage of 10,000 IU significantly alleviated their symptoms when a cold struck, highlighting the importance of adjusting the dose during illness (Read Review). Another user noted their positive experience with the supplement, stating it helped them avoid cold or flu symptoms entirely during the season (Read Review), suggesting that when taken alongside good practices and possibly other supplements, the benefits can be more pronounced.
Additionally, a review indicated that the vitamin D3 had a significant impact on immunity, especially during cold episodes, reinforcing the idea that users often use it in conjunction with a comprehensive health strategy to bolster their defenses against seasonal ailments (Read Review). Overall, many users seem to appreciate the supplement's role as part of a wider arsenal against colds, particularly in challenging climates where immune support is crucial.
Research suggests that vitamin D can play a role in alleviating cold symptoms, with doses varying across studies. For instance, one study indicated that a daily dose of 800 IU of vitamin D contributed to fewer mild respiratory symptoms and quicker recovery in children diagnosed with respiratory infections [1]. Another research highlighted that doses exceeding 1,000 IU daily led to significant reductions in the occurrence of colds, coughs, and fevers among younger populations [2].
Additionally, a systematic examination of participants with lower vitamin D levels showed that taking 10 µg (approximately 400 IU) of vitamin D3 for 16 weeks significantly reduced symptoms such as a runny nose and head congestion [5]. Another related study confirmed similar outcomes, noting that the same dose not only reduced symptom severity but also improved overall quality of life during upper respiratory infections [6]. Taken together, while no one-size-fits-all dose has been definitively established, it appears that a range between 400-1,000 IU may be beneficial for managing cold symptoms in varying age groups.
9
Rapid symptom relief
So far, so good! I initially tried this product and found it more expensive than others. However, I purchased a second bottle because I noticed that when I felt a cold and sore throat coming on, taking 2 pills of 10,000 iu in the late morning helped alleviate symptoms by evening.
6
Shortened cold duration
The cold lasted less than 28 hours, and it felt very light. It has positively impacted my immune system.
9
Boosts immune system
Amazing small, convenient for a pill box and easy to swallow. It has the best absorbency, is potent, and makes me feel less fatigued. My moods and energy are better. I love this stuff. I've used it to boost my immune system, and I haven't had any cold or flu symptoms this season. The quality is great—very effective vitamin D that truly aids with seasonal affective disorder!
7.5
Helps during colds
Vitamin D3 boosts immunity significantly and helps a great deal during cold episodes.
8
Vitamin D reduces cold severity
Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.
We explored the connection between vitamin D levels and upper respiratory tract infections (URTIs) among military recruits during their training. This observation spanned across different seasons and included over 1,600 recruits. Our aim was to understand how achieving sufficient vitamin D levels could potentially impact the frequency and severity of colds among physically active individuals.
In an additional phase of the research, we conducted a randomized controlled trial with 250 male recruits. They received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplements during winter. This comparison allowed us to see if these methods effectively increased vitamin D levels to a sufficient status of 25(OH)D at 50 nmol/L or higher.
Notably, our findings showed that only 21% of recruits had adequate vitamin D during winter, yet those who did were 40% less likely to suffer from URTIs. Furthermore, both vitamin D supplementation strategies similarly helped nearly all participants achieve sufficient levels. Vitamin D supplementation notably reduced the severity of URTI symptoms by 15% and the number of days with URTIs by 36% compared to placebo.
While the supplementation strategies did not significantly alter other immune factors, such as salivary secretory immunoglobulin A, the overall reduction in respiratory infections indicates a beneficial effect of maintaining vitamin D sufficiency during military training.
7
Vitamin D's limited cold impact
High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 months: a systematic review and meta-analysis.
We evaluated the impact of high-dose vitamin D supplementation, specifically doses exceeding the standard 400 IU, on preventing colds and other infections in children under five years of age. Our analysis included seven studies, involving a total of 5,748 children, which looked into how effective vitamin D might be in reducing the incidence of upper respiratory tract infections.
Interestingly, while our findings showed no significant benefit of high-dose vitamin D on the prevention of upper respiratory tract infections as a whole, we did observe a noteworthy reduction in specific illness occurrences. We noted a 57% reduction in colds, a 56% reduction in coughs, and a 59% decrease in fever rates with daily doses exceeding 1,000 IU.
However, we must approach these findings with caution, as the evidence supporting the reduction in cough and fever was of lower certainty. No significant effects were observed regarding other conditions such as bronchitis or otitis media. Overall, while high-dose vitamin D may help with colds specifically, further research is needed to solidify these conclusions.
8
Vitamin D3 aids cold recovery
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored how 25-hydroxyvitamin D3 (25OHD), a form of vitamin D, influences upper respiratory tract infections (URTIs), commonly known as colds. In a carefully designed clinical study, we followed 428 participants aged 45 to 74 over a 16-week period. They were randomly assigned to receive either 10 μg of 25OHD daily or a placebo, all while maintaining a double-blind setup to ensure accurate results.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
5
Vitamin D and cold symptoms
The Effects of Vitamin D Supplementation on Respiratory Infections in Children under 6 Years Old: A Systematic Review.
We explored the effects of vitamin D supplementation on respiratory infections, particularly colds, in children under six years old. By examining various studies published until February 2023, we observed diverse findings, with some studies reporting benefits while others found no significant advantage. Overall, eight studies were included, with a total of 2,189 children assessed.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
7
Vitamin D reduces cold symptoms
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored the effects of 25-hydroxyvitamin D (25OHD) on individuals experiencing upper respiratory tract infections (URTIs), commonly known as colds. In a well-structured study, participants with low vitamin D levels received either a daily dose of 10 micrograms of 25OHD or a placebo for a span of 16 weeks. The participants' symptoms were assessed using the Wisconsin Upper Respiratory Symptom Survey-21, focusing on how the vitamin impacted their cold symptoms.
Our findings showed that those taking 25OHD reported significant reductions in physical symptoms such as runny noses, sneezing, and head congestion compared to those on the placebo. Additionally, the quality of life scores improved for most symptoms, except for ease of breathing. However, it’s important to note that there was no significant difference in the total number of cold events or how often participants used medications like antibiotics or pain relievers.
Collectively, these results suggest that adequate intake of vitamin D can help ease cold symptoms, particularly those affecting the nose, and might enhance overall well-being when a cold strikes. This indicates that vitamin D may play a positive role in managing the discomfort associated with upper respiratory infections.
References
Marusca LM, Reddy G, Blaj M, Prathipati R, Rosca O, et al. The Effects of Vitamin D Supplementation on Respiratory Infections in Children under 6 Years Old: A Systematic Review. Diseases. 2023;11. doi:10.3390/diseases11030104
Carboo JA, Dolman-Macleod RC, Malan L, Lombard MJ. High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 months: a systematic review and meta-analysis. Nutr Rev. 2024;82:579. doi:10.1093/nutrit/nuad082
Kisla Ekinci RM, Taskin Karacay IE, Celik U. Serum vitamin B12 and D levels in children with Primary Raynaud Phenomenon: a retrospective cohort study. Eur J Clin Nutr. 2022;76:1615. doi:10.1038/s41430-022-01151-0
Harrison SE, Oliver SJ, Kashi DS, Carswell AT, Edwards JP, et al. Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training. Med Sci Sports Exerc. 2021;53:1505. doi:10.1249/MSS.0000000000002604
Shimizu Y, Ito Y, Uotsu N, Yui K. Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. Nutrients. 2020;12. doi:10.3390/nu12123769
Shimizu Y, Ito Y, Yui K, Egawa K, Orimo H. Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. J Nutr Health Aging. 2018;22:491. doi:10.1007/s12603-017-0952-x