' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 2 Researches
8
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
Supplement Facts
Serving Size: 2 Gummies
Serving Per Container: 30
Amount Per Serving
%DV
Calories
20
Total Carbohydrate
5 g
2%**
Total Sugars
3 g
†
Includes 3 g Added Sugars
6%**
Vitamin C
45 mg
50%
Zinc
7.5 mg
68%
Sodium
15 mg
<1%
Organic Black Elderberry Concentrate (Sambucus nigra) (fruit) (65:1)
150 mg
†
Organic VitaBerry® Fruit BlendStrawberry, Raspberry, Blueberry, Tart Cherry, Elderberry, Cranberry Powders
25 mg
†
Bacillus coagulans (Lactospore®)
10 mg(1 Billion CFU)
†
Top Medical Research Studies
8
Vitamin C's impact on constipation
Feasibility study for a fully decentralized clinical trial in participants with functional constipation symptoms.
Moderate relevance due to vitamin C pairing
We conducted a fully decentralized clinical trial to explore the effects of vitamin C on constipation symptoms. Participants who experienced functional constipation were randomly assigned to receive either Lactobacillus with vitamin C or vitamin C alone over a two-week treatment period. The study allowed us to gather data remotely, which is quite innovative and accessible.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
Read More
8
Zinc may mitigate granisetron constipation
Carbon monoxide contributes to the constipating effects of granisetron in rat colon.
Specific interaction with granisetron
We investigated how zinc might play a role in alleviating the constipation effects caused by granisetron, a medication often used to prevent nausea. In the studies, male rats were treated with varying doses of granisetron, alongside zinc protoporphyrin IX (ZnPPIX), to see how these compounds interacted.
Interestingly, while granisetron was found to increase the time to first defecation in the rats, ZnPPIX alone did not have a notable effect on constipation. However, when combined with granisetron, ZnPPIX successfully reversed the constipation induced by this medication. This suggests that zinc, acting through the heme oxygenase/carbon monoxide (HO/CO) pathway, could potentially mitigate constipation.
Nonetheless, it’s crucial to note that ZnPPIX’s effectiveness was only observed when paired with granisetron; its standalone administration didn’t significantly alter gastrointestinal motility. This highlights a specific interaction rather than a general benefit of zinc in treating constipation.
Interestingly, while granisetron was found to increase the time to first defecation in the rats, ZnPPIX alone did not have a notable effect on constipation. However, when combined with granisetron, ZnPPIX successfully reversed the constipation induced by this medication. This suggests that zinc, acting through the heme oxygenase/carbon monoxide (HO/CO) pathway, could potentially mitigate constipation.
Nonetheless, it’s crucial to note that ZnPPIX’s effectiveness was only observed when paired with granisetron; its standalone administration didn’t significantly alter gastrointestinal motility. This highlights a specific interaction rather than a general benefit of zinc in treating constipation.
Read More
Most Useful Reviews
9.5
Constipation improved
I liked it! Upon opening the jar, a distinct berry aroma is noticeable, while the taste is lighter. I purchased it for its berry mix (elderberry, raspberry, cherry, strawberry, cranberry) and probiotics, as I also provide vitamin C to my children, being cautious with zinc. However, the jellies are stuck together and need separating. Notably, my son, aged 5, who struggled with constipation, has seen a significant improvement after taking these jellies to support his immunity. I'm truly impressed!
Read More
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Medical Researches
SCIENTIFIC SCORE
Most Likely Effective
Based on 2 Researches
8
8
Vitamin C's impact on constipation
Feasibility study for a fully decentralized clinical trial in participants with functional constipation symptoms.
Moderate relevance due to vitamin C pairing
We conducted a fully decentralized clinical trial to explore the effects of vitamin C on constipation symptoms. Participants who experienced functional constipation were randomly assigned to receive either Lactobacillus with vitamin C or vitamin C alone over a two-week treatment period. The study allowed us to gather data remotely, which is quite innovative and accessible.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
Read More
8
Zinc may mitigate granisetron constipation
Carbon monoxide contributes to the constipating effects of granisetron in rat colon.
Specific interaction with granisetron
We investigated how zinc might play a role in alleviating the constipation effects caused by granisetron, a medication often used to prevent nausea. In the studies, male rats were treated with varying doses of granisetron, alongside zinc protoporphyrin IX (ZnPPIX), to see how these compounds interacted.
Interestingly, while granisetron was found to increase the time to first defecation in the rats, ZnPPIX alone did not have a notable effect on constipation. However, when combined with granisetron, ZnPPIX successfully reversed the constipation induced by this medication. This suggests that zinc, acting through the heme oxygenase/carbon monoxide (HO/CO) pathway, could potentially mitigate constipation.
Nonetheless, it’s crucial to note that ZnPPIX’s effectiveness was only observed when paired with granisetron; its standalone administration didn’t significantly alter gastrointestinal motility. This highlights a specific interaction rather than a general benefit of zinc in treating constipation.
Interestingly, while granisetron was found to increase the time to first defecation in the rats, ZnPPIX alone did not have a notable effect on constipation. However, when combined with granisetron, ZnPPIX successfully reversed the constipation induced by this medication. This suggests that zinc, acting through the heme oxygenase/carbon monoxide (HO/CO) pathway, could potentially mitigate constipation.
Nonetheless, it’s crucial to note that ZnPPIX’s effectiveness was only observed when paired with granisetron; its standalone administration didn’t significantly alter gastrointestinal motility. This highlights a specific interaction rather than a general benefit of zinc in treating constipation.
Read More
User Reviews
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9.5
Constipation improved
I liked it! Upon opening the jar, a distinct berry aroma is noticeable, while the taste is lighter. I purchased it for its berry mix (elderberry, raspberry, cherry, strawberry, cranberry) and probiotics, as I also provide vitamin C to my children, being cautious with zinc. However, the jellies are stuck together and need separating. Notably, my son, aged 5, who struggled with constipation, has seen a significant improvement after taking these jellies to support his immunity. I'm truly impressed!
Read More
