There is limited scientific evidence to support the use of Biotin for preventing or helping with Multiple sclerosis (MS). Biotin, also known as vitamin B7, is involved in various processes in the body, including the production of energy and supporting the health of skin, hair, and nails. Some research suggests that Biotin may have neuroprotective properties and play a role in myelin repair, which is of particular interest in the context of MS, a condition characterized by the damage of the protective covering of nerve fibers.
A small pilot study published in 2015 showed that high-dose Biotin supplementation (300 mg/day) was associated with clinical improvements in MS patients. However, it is important to note that this study had several limitations, including a small sample size and lack of a control group. Moreover, subsequent larger and more rigorous clinical trials failed to demonstrate significant benefits of Biotin in MS. For example, a randomized-controlled trial involving 154 MS patients found no difference in disease progression or disability between those taking high-dose Biotin and those receiving a placebo.
