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Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Total Carbohydrate
<1g
<1%†
Calcium (from calcium magnesium phytate)
131 mg
10%
Phosphorus (from calcium magnesium phytate)
192 mg
15%
Magnesium (from calcium magnesium phytate)
40 mg
10%
IP-6 (inositol hexaphosphate) (from calcium magnesium phytate)
800 mg
**
Inositol
220 mg
**
Maitake Mushroom Extract standardized to 30% pure D-fraction (9 mg)
30 mg
**
Cat's Claw Extract (bark) standardized to 4% alkaloids (0.4 mg)
10 mg
**
The product is found useful for the following medical conditions
Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 33 Researches
7.9
USERS' SCORE
Good
Based on 29 Reviews
8.9
9
Myo-inositol affects prostate cancer cells
Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line.
Most Relevant Research
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
9.5
Remission success
Most Useful Review
READ THIS—MAX3 HELPS KILL GLIOBLASTOMA BRAIN CANCER. This product has put my Mum in remission from glioblastoma brain cancer! With MAX3, MSM, Frankincense pills, and black seed oil, her MRIs have been clear! This cancer was deemed a death sentence, yet here she is happily wearing her beautiful wigs. I have been advised to make her "eat" this all day. Her immune system is functioning exceptionally well and combating cancer. I firmly believe this product, among others, has kept her healthy and alive. While she is undergoing chemotherapy and radiation treatments, she occasionally feels a bit "run down".
Lung Cancer details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.3
USERS' SCORE
Good
Based on 4 Reviews
8.7
9
IP shows potential in lung cancer
Intrathecal pemetrexed improves survival outcomes in previously treated EGFR-mutant advanced non-small-cell lung cancer with leptomeningeal metastases.
Most Relevant Research
We explored the effects of intrathecal pemetrexed (IP) on lung cancer patients facing leptomeningeal metastases (LM), particularly after they had not responded to previous treatments with EGFR-TKIs. The study analyzed 50 patients who received a 50 mg dose of IP after their cancer progressed, looking closely at their clinical responses and survival outcomes over two years.
Remarkably, we observed a 64% clinical response rate, indicating that many patients saw improvements in their neurological symptoms and overall performance. The median intracranial progression-free survival was 5.3 months, while overall survival reached up to 12 months for these patients. Those who responded positively to the treatment experienced significantly longer survival compared to non-responders, which is encouraging for both patients and doctors seeking options after traditional therapies fail.
The treatment was generally well tolerated, with manageable side effects mostly related to myelosuppression and liver functions. Additionally, genetic testing revealed consistency between the tumors and the cerebrospinal fluid, which opens up further investigation into the underlying mechanisms of treatment resistance. Overall, our findings suggest that IP could be a promising option for patients battling advanced lung cancer with LM after existing therapies have stopped working.
Remarkably, we observed a 64% clinical response rate, indicating that many patients saw improvements in their neurological symptoms and overall performance. The median intracranial progression-free survival was 5.3 months, while overall survival reached up to 12 months for these patients. Those who responded positively to the treatment experienced significantly longer survival compared to non-responders, which is encouraging for both patients and doctors seeking options after traditional therapies fail.
The treatment was generally well tolerated, with manageable side effects mostly related to myelosuppression and liver functions. Additionally, genetic testing revealed consistency between the tumors and the cerebrospinal fluid, which opens up further investigation into the underlying mechanisms of treatment resistance. Overall, our findings suggest that IP could be a promising option for patients battling advanced lung cancer with LM after existing therapies have stopped working.
9.5
Notable improvement
Most Useful Review
Last July, my small dog, 9 years old, was diagnosed with lung cancer and given only 4 months to live without treatment. She struggled to breathe, with frequent gagging. Chemotherapy nearly killed her, and it seemed metastasis had begun during treatment. After starting her on Max3 and a grain-free diet, I noticed a marked improvement. Over 10 months later, she is thriving, gagging just once each morning. Unfortunately, my local store switched to a less convenient version of my supplement, but I ordered the original online. I feel this change impacted effectiveness, so I supplemented it with immune boosters.
Autoimmune Disorder details
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.6
7
Cat's claw shows potential benefits
Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis.
Most Relevant Research
We explored the effectiveness of cat's claw in managing autoimmune disorders, specifically osteoarthritis (OA) and rheumatoid arthritis (RA). Our review included various studies, focusing on its potential as a dietary supplement to reduce inflammation and oxidative stress associated with these conditions.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
8.8
Supports recovery
Most Useful Review
I have been taking Cell Forte MAX3 for a few months after being diagnosed with an autoimmune disorder and starting chemotherapy and immunotherapy. I feel that MAX3 has helped keep my body fit during this process. The product seems to be of good quality, and I believe it has benefitted me alongside a balanced diet. I am on my second batch and will reorder more.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Improved energy levels
Most Useful Review
I highly recommend this product. Since contracting Covid-19, I experienced unstable blood sugar, dizziness, and fatigue, feeling colder than usual. I discovered that IP6 could stabilise various bodily systems, and this formula, enriched with immune-boosting mushrooms, has significantly improved my condition. Within just two days of using it, my energy has restored by more than half from my previous state of chronic fatigue syndrome. I'm incredibly grateful to iHerb for offering such a remarkable product.
Common Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 11 Reviews
8.6
9.5
Relieves cold symptoms
Most Useful Review
I truly like this product and take it regularly for myself and a friend. It effectively alleviates cold symptoms and speeds up recovery without causing drowsiness or other unpleasant side effects. At the first signs of illness, I increase my dose and return to the usual amount the next day. I feel it enhances my immunity. All in all, good health!
Pneumonia details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Effective pneumonia remedy
Most Useful Review
AWESOME! I have been taking this product since 2001 when I had pneumonia and struggled to recover. My chiropractor recommended it, and I felt better almost immediately. Now, whenever I sense something coming on, I take it straight away, and the symptoms vanish within hours. This works brilliantly and is a superb alternative to antibiotics.
Flu details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.6
9.5
Immune system boost
Most Useful Review
I highly recommend this product as it greatly boosted my immune system. I've been around numerous individuals with flu and colds, yet it hasn't affected me at all.
Breast Cancer details
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Maitake polysaccharide shows cancer potential
Polysaccharide isolated from eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T cells responses.
Most Relevant Research
We investigated how a fungal polysaccharide extracted from maitake mushrooms can impact breast cancer. This treatment approach focuses on myeloid-derived suppressor cells, or MDSCs, which are known to help tumors grow by suppressing the immune response in cancer patients.
Our findings revealed that the maitake polysaccharide, referred to as GFI, significantly reduces the number of MDSCs in the bloodstream and tumor tissue in mice, resulting in slower tumor growth. Interestingly, GFI particularly targets a subset of MDSCs known as PMN-MDSCs, while leaving another type, M-MDSCs, largely unaffected.
We also observed that GFI not only clears out these immune suppressing cells but also revives and activates CD8 T cells, which are crucial for attacking tumors. This dual action enhances the body's natural defenses against cancer, suggesting that GFI could serve as a promising treatment option for breast cancer patients.
Altogether, our study sheds light on an innovative approach to battling breast cancer, further emphasizing the potential of natural compounds derived from mushrooms in cancer therapy.
Our findings revealed that the maitake polysaccharide, referred to as GFI, significantly reduces the number of MDSCs in the bloodstream and tumor tissue in mice, resulting in slower tumor growth. Interestingly, GFI particularly targets a subset of MDSCs known as PMN-MDSCs, while leaving another type, M-MDSCs, largely unaffected.
We also observed that GFI not only clears out these immune suppressing cells but also revives and activates CD8 T cells, which are crucial for attacking tumors. This dual action enhances the body's natural defenses against cancer, suggesting that GFI could serve as a promising treatment option for breast cancer patients.
Altogether, our study sheds light on an innovative approach to battling breast cancer, further emphasizing the potential of natural compounds derived from mushrooms in cancer therapy.
8.8
Supports immune system
Most Useful Review
I purchase this product for my mum, a breast cancer survivor at 86. It effectively builds her immune system and keeps her strong. I truly love it!
Liver Disease details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Maitake improves diabetes-related liver health
Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice.
Most Relevant Research
We evaluated the impact of an alpha-glucan extracted from maitake mushrooms on mice with a model of type 2 diabetes. This study specifically focused on various health markers related to liver function and diabetes.
By administering two different doses of the maitake mushroom extract, we observed significant improvements across several measures in diabetic mice. The treatment led to reductions in body weight, fasting blood sugar levels, and harmful substances like triglycerides and cholesterol.
Notably, we found that liver functions improved as evidenced by increased levels of beneficial substances like glycogen and reduced oxidative stress markers. Additionally, we observed enhanced insulin sensitivity, which is crucial for managing diabetes effectively.
These findings suggest that maitake mushrooms may offer tangible benefits not only for diabetes management but specifically for protecting and improving liver health in affected individuals.
By administering two different doses of the maitake mushroom extract, we observed significant improvements across several measures in diabetic mice. The treatment led to reductions in body weight, fasting blood sugar levels, and harmful substances like triglycerides and cholesterol.
Notably, we found that liver functions improved as evidenced by increased levels of beneficial substances like glycogen and reduced oxidative stress markers. Additionally, we observed enhanced insulin sensitivity, which is crucial for managing diabetes effectively.
These findings suggest that maitake mushrooms may offer tangible benefits not only for diabetes management but specifically for protecting and improving liver health in affected individuals.
8.8
Ferritin reduction
Most Useful Review
I initially used Nature's Way products for high ferritin levels, which were concerning due to my fatty liver. After two months on the product, my ferritin significantly decreased, and my liver function tests also improved, surprising me. I later tried IP6 Gold, but the decrease in ferritin became much slower. I plan to return to Nature's Way to see if the results can be replicated.
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.5
USERS' SCORE
Good
Based on 7 Reviews
8.5
8
Inositol enhances rapeseed cold tolerance
Inositol Improves Cold Tolerance Through Inhibiting and Increasing Ca Influx in Rapeseed ( L.).
Most Relevant Research
We explored the impact of inositol on cold stress in rapeseed, an essential oilseed crop affected by low temperatures. Notably, we found that inositol plays a significant role in enhancing cold tolerance in these plants by boosting calcium ion (Ca) influx.
Our study involved identifying various genes associated with inositol and analyzing their expression under cold conditions. Interestingly, inositol appeared to inhibit the expression of calcineurin B-like genes, which are involved in regulating calcium flow, suggesting a unique pathway through which inositol aids in cold resilience.
Additionally, when we overexpressed certain genes linked to calcium flux, we noted a stronger response to cold stress, further emphasizing the importance of the inositol-Ca pathway in facilitating cold tolerance in rapeseed. These findings not only deepen our understanding of how rapeseed copes with cold conditions but also present a potential strategy for enhancing crop resilience in the face of climate challenges.
Our study involved identifying various genes associated with inositol and analyzing their expression under cold conditions. Interestingly, inositol appeared to inhibit the expression of calcineurin B-like genes, which are involved in regulating calcium flow, suggesting a unique pathway through which inositol aids in cold resilience.
Additionally, when we overexpressed certain genes linked to calcium flux, we noted a stronger response to cold stress, further emphasizing the importance of the inositol-Ca pathway in facilitating cold tolerance in rapeseed. These findings not only deepen our understanding of how rapeseed copes with cold conditions but also present a potential strategy for enhancing crop resilience in the face of climate challenges.
8.8
Light colds only
Most Useful Review
Don’t let any cold get you down. I have read many reviews but this product truly deserves high praise. When I sense a cold coming on, I start taking it as per the instructions, which makes the cold feel light. Sometimes, I forget I even had a cold when I neglect to take it. It’s a standard item in my home and for my loved ones.
