We aimed to explore how magnesium ascorbyl phosphate (MAP), a stable form of vitamin C, influences acne by evaluating its impact on inflammatory responses in skin cells known as sebocytes. The study employed a robust methodology, where we treated cultured sebocytes with different solutions: MAP, lipopolysaccharide (LPS), and a combination of both.
Following treatment, we measured the expression of inflammatory markers, cytokines, and proteins involved in skin inflammation and the healing process. Our findings revealed that MAP effectively reduced the heightened inflammatory responses caused by LPS, suggesting it has a calming effect on acne-related inflammation.
Additionally, we observed a notable decrease in lipid peroxidation, a contributor to skin damage, after treatment with MAP. This means that vitamin C may not only help reduce inflammation but could also protect skin cells from oxidative stress, promoting healthier skin overall.
In summary, our study strengthens the idea that using MAP can be a beneficial addition to acne treatments, potentially leading to improved skin conditions.