Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 1 Review
8.4
Top Medical Research Studies
7
We explored the link between serum ferritin levels and androgenetic alopecia (AGA) among individuals at a dermatology clinic in Nigeria. Our study included 114 participants, divided evenly between those with AGA and healthy individuals. We found that people with AGA had significantly lower serum ferritin levels, suggesting that iron deficiency may impact hair growth. However, while low iron might play a role, genetic factors also contribute to AGA.
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7
We explored the connection between iron deficiency and nonscarring alopecia in women through a systematic review of existing studies. Our analysis included 36 studies with over 10,000 participants.
Although we found that women with hair loss had lower ferritin levels, the evidence for iron deficiency directly causing this type of hair loss remains inconclusive. Still, having higher ferritin levels seems beneficial for women experiencing hair loss, suggesting a possible area for further investigation.
Although we found that women with hair loss had lower ferritin levels, the evidence for iron deficiency directly causing this type of hair loss remains inconclusive. Still, having higher ferritin levels seems beneficial for women experiencing hair loss, suggesting a possible area for further investigation.
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9.5
We investigated the effectiveness of a novel microneedle system that uses mesoporous iron oxide to deliver Minoxidil, a hair loss treatment, directly to the scalp.
This method overcomes common barriers in medication delivery while enhancing absorption.
The results were promising, showing an impressive 800% increase in hair density in mice treated with this system after just ten days.
However, additional research is necessary to confirm these findings in humans and assess the treatment's long-term benefits.
This method overcomes common barriers in medication delivery while enhancing absorption.
The results were promising, showing an impressive 800% increase in hair density in mice treated with this system after just ten days.
However, additional research is necessary to confirm these findings in humans and assess the treatment's long-term benefits.
Read More
Most Useful Reviews
7.5
Stops shedding hair
3 people found this helpful
These vitamins are suitable for adults too and available at a great price on Amazon. I discovered I was iron deficient when I started feeling unusually tired and noticed an increase in hair shedding and hair loss on my scalp. At 36, this was alarming for me as a woman. Since I began taking two daily, my iron levels have normalised, I feel more energetic, and I have not seen a worsening in hair loss.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
- All Researches
9.5
We investigated the effectiveness of a novel microneedle system that uses mesoporous iron oxide to deliver Minoxidil, a hair loss treatment, directly to the scalp.
This method overcomes common barriers in medication delivery while enhancing absorption.
The results were promising, showing an impressive 800% increase in hair density in mice treated with this system after just ten days.
However, additional research is necessary to confirm these findings in humans and assess the treatment's long-term benefits.
This method overcomes common barriers in medication delivery while enhancing absorption.
The results were promising, showing an impressive 800% increase in hair density in mice treated with this system after just ten days.
However, additional research is necessary to confirm these findings in humans and assess the treatment's long-term benefits.
Read More
8
We investigated the use of iron chelators in addressing autoimmune-induced hair loss, particularly alopecia areata. By focusing on therapies that stabilize hypoxia-inducible factor 1-alpha, we found that these treatments could significantly enhance hair density, thickness, and elasticity.
In clinical trials, participants experienced a reduction in hair loss by up to 66.8% over six months. These results reveal the potential of iron chelators, like deferoxamine and deferiprone, in supporting hair restoration for those affected by autoimmune conditions.
As we look ahead, combining these chelators with immune-modulating therapies may offer even greater benefits in managing alopecia.
In clinical trials, participants experienced a reduction in hair loss by up to 66.8% over six months. These results reveal the potential of iron chelators, like deferoxamine and deferiprone, in supporting hair restoration for those affected by autoimmune conditions.
As we look ahead, combining these chelators with immune-modulating therapies may offer even greater benefits in managing alopecia.
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We aimed to understand whether an oral supplement with hydrolyzed collagen, amino acids, iron, and selenium could enhance hair growth for those dealing with androgenetic alopecia and chronic telogen effluvium.
In a controlled study with 83 participants, half received the supplement along with their usual treatments, while the other half used only the treatments. After 12 weeks, our findings indicated that the supplement did indeed show improvement in hair loss symptoms compared to treatments alone.
While the results were promising, it’s essential for individuals to consult their healthcare providers before making any changes to their treatment plans.
In a controlled study with 83 participants, half received the supplement along with their usual treatments, while the other half used only the treatments. After 12 weeks, our findings indicated that the supplement did indeed show improvement in hair loss symptoms compared to treatments alone.
While the results were promising, it’s essential for individuals to consult their healthcare providers before making any changes to their treatment plans.
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8
Oral supplement aids hair growth
We aimed to explore the effectiveness of a new oral supplement on hair loss in women experiencing telogen effluvium, some alongside mild to moderate androgenetic alopecia. Our study involved 20 female participants who took a supplement rich in amino acids and important trace elements, including iron.
Over six months, through dermatological tests and photography, we observed significant improvements in hair growth and reduction in hair loss. Importantly, all patients tolerated the treatment well, making it a convenient option for many.
Over six months, through dermatological tests and photography, we observed significant improvements in hair growth and reduction in hair loss. Importantly, all patients tolerated the treatment well, making it a convenient option for many.
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8
We investigated the effects of HIF-1α modulators on hair loss and compared them with traditional treatments like minoxidil and caffeine. Using a specialized method, we cultured dermal papilla cells to resemble their natural structure.
Our findings showed that both HIF-1α stimulators and standard treatments significantly encouraged cell growth. Notably, the HIF-1α compound performed on par with minoxidil, suggesting it could be a viable alternative for hair loss management.
Our findings showed that both HIF-1α stimulators and standard treatments significantly encouraged cell growth. Notably, the HIF-1α compound performed on par with minoxidil, suggesting it could be a viable alternative for hair loss management.
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User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Stops shedding hair
3 people found this helpful
These vitamins are suitable for adults too and available at a great price on Amazon. I discovered I was iron deficient when I started feeling unusually tired and noticed an increase in hair shedding and hair loss on my scalp. At 36, this was alarming for me as a woman. Since I began taking two daily, my iron levels have normalised, I feel more energetic, and I have not seen a worsening in hair loss.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Pagani A, Thor D, Panayi AC, Klein SM, Geis S, et al. Iron Chelators in the Management of Autoimmune-Induced Alopecia: A Focus on Hypoxia-Inducible Factor 1 Modulation and Hair Restoration. J Clin Med. 2025;14. doi:10.3390/jcm14072133
- Wang R, Lin J, Liu Q, Wu W, Wu J, et al. Micronutrients and Androgenetic Alopecia: A Systematic Review. Mol Nutr Food Res. 2024;68:e2400652. doi:10.1002/mnfr.202400652
- Bilik L, Kokcam I, Esen M. Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin B12 levels. North Clin Istanb. 2024;11:38. doi:10.14744/nci.2023.33269
- Wang T, Yang C, Li Z, Li T, Zhang R, et al. Flavonoid 4,4'-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy. Redox Biol. 2024;69:103017. doi:10.1016/j.redox.2023.103017
- Lin CS, Chan LY, Wang JH, Chang CH. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia. Tzu Chi Med J. 2023;35:322. doi:10.4103/tcmj.tcmj_95_23
- Milani M, Colombo F. Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study. Skin Res Technol. 2023;29:e13381. doi:10.1111/srt.13381
- Starace M, Carpanese MA, Alessandrini A, Bruni F, Piraccini BM. Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic treatment. Ital J Dermatol Venerol. 2023;158:55. doi:10.23736/S2784-8671.22.07416-3
- Enitan AO, Olasode OA, Onayemi EO, Ajani AA, Olanrewaju FO, et al. Serum Ferritin Levels amongst Individuals with Androgenetic Alopecia in Ile-Ife, Nigeria. West Afr J Med. 2022;39:1026.
- Treister-Goltzman Y, Yarza S, Peleg R. Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis. Skin Appendage Disord. 2022;8:83. doi:10.1159/000519952
- Beatrix J, Piales C, Berland P, Marchiset E, Gerbaud L, et al. Non-anemic iron deficiency: correlations between symptoms and iron status parameters. Eur J Clin Nutr. 2022;76:835. doi:10.1038/s41430-021-01047-5
- Bukowiecki J, Pförringer D, Thor D, Duscher D, Brett E. HIF-1α Stimulators Function Equally to Leading Hair Loss Agents in Enhancing Dermal Papilla Growth. Skin Pharmacol Physiol. 2020;33:309. doi:10.1159/000512123
- Kondrakhina IN, Verbenko DA, Zatevalov AM, Gatiatulina ER, Nikonorov AA, et al. A Cross-sectional Study of Plasma Trace Elements and Vitamins Content in Androgenetic Alopecia in Men. Biol Trace Elem Res. 2021;199:3232. doi:10.1007/s12011-020-02468-2
- Salinas M, Leiva-Salinas M, Flores E, López-Garrigós M, Leiva-Salinas C. Alopecia and Iron Deficiency: An Interventional Pilot Study in Primary Care to Improve the Request of Ferritin. Adv Hematol. 2020;2020:7341018. doi:10.1155/2020/7341018
- Tamer F, Yuksel ME, Karabag Y. Serum ferritin and vitamin D levels should be evaluated in patients with diffuse hair loss prior to treatment. Postepy Dermatol Alergol. 2020;37:407. doi:10.5114/ada.2020.96251
- Fang JH, Liu CH, Hsu RS, Chen YY, Chiang WH, et al. Transdermal Composite Microneedle Composed of Mesoporous Iron Oxide Nanoraspberry and PVA for Androgenetic Alopecia Treatment. Polymers (Basel). 2020;12. doi:10.3390/polym12061392
- Fernandez-Jimenez MC, Moreno G, Wright I, Shih PC, Vaquero MP, et al. Iron Deficiency in Menstruating Adult Women: Much More than Anemia. Womens Health Rep (New Rochelle). 2020;1:26. doi:10.1089/whr.2019.0011
